دورية أكاديمية
Dependence of the allergic status markers on the level of vitamin D in the serum
| العنوان: | Dependence of the allergic status markers on the level of vitamin D in the serum |
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| المؤلفون: | Dajić Katerina, Stojković Nebojša, Novković Ljiljana, Vujić Ana, Stojković Anđelka |
| المصدر: | Srpski Arhiv za Celokupno Lekarstvo, Vol 147, Iss 9-10, Pp 560-566 (2019) |
| بيانات النشر: | Serbian Medical Society, 2019. |
| سنة النشر: | 2019 |
| المجموعة: | LCC:Medicine |
| مصطلحات موضوعية: | immunoglobulin e, vitamin d, child, allergen, Medicine |
| الوصف: | Introduction/Objective. Recent researches show a link between low vitamin D serum levels and increased prevalence of allergic disease. The objective of this study was to show whether there is any dependence of the allergic status markers: skin prick test (SPT), total immunoglobulin E IgE (tIgE), and allergen-specific IgE (sIgE ≥ 3 class) in serum from the serum 25(OH)D (vitDs) level in children with allergic disease/s. Methods. A total of 150 children with allergic disease/s were enrolled into this study. The vitDs, tIgE, SPT, and sIgE ≥ 3 class for aeroallergens and common food allergens were simultaneously assessed. Results. We found a negative correlation between vitDs level and age groups and a statistically significant positive correlation between vitDs level and tIgE, sIgE ≥ 3 class for hen’s egg yolk and hen’s egg white. A statistically significant positive correlation was determined between vitDs level and SPT on Dermatophagoides pteronyssinus, and a negative correlation between tIgE and SPT on Dermatophagoides pteronyssinus, as well as between vitDs level and sIgE ≥ 3 class for Cladosporium and Alternaria molds. We confirmed the dependence of nettle rash and comorbidity asthma from the vitamin D insufficiency and vitamin D deficiency. We did not find any dependence of serum tIgE on vitDs level for the sample. Conclusion. In order to get an adequate insight into the allergic status in children, we must take into account the pleotropic effects of vitamin D, according to which we suggest that, in the future, vitDs level should be determined synchronously with known markers of allergic status. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English Serbian |
| تدمد: | 0370-8179 |
| العلاقة: | https://doaj.org/toc/0370-8179Test |
| DOI: | 10.2298/SARH180822025D |
| الوصول الحر: | https://doaj.org/article/43589d1e6f2548289348d58e1339f8cdTest |
| رقم الانضمام: | edsdoj.43589d1e6f2548289348d58e1339f8cd |
| قاعدة البيانات: | Directory of Open Access Journals |
| تدمد: | 03708179 |
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| DOI: | 10.2298/SARH180822025D |