Dosimetric accuracy of dynamic couch rotation during volumetric modulated arc therapy (DCR-VMAT) for primary brain tumours

التفاصيل البيبلوغرافية
العنوان: Dosimetric accuracy of dynamic couch rotation during volumetric modulated arc therapy (DCR-VMAT) for primary brain tumours
المؤلفون: Smyth, Gregory, Evans, Philip M., Bamber, Jeffrey C, Mandeville, Henry C, Rollo Moore, A, Welsh, Liam C, Saran, Frank H, Bedford, James L
سنة النشر: 2019
مصطلحات موضوعية: Organs at Risk, Rotation, Brain Neoplasms, Radiotherapy Planning, Computer-Assisted, Humans, Radiotherapy Dosage, Radiotherapy, Intensity-Modulated, Particle Accelerators, Article, Algorithms, Patient Positioning
الوصف: Radiotherapy treatment plans using dynamic couch rotation during volumetric modulated arc therapy (DCR-VMAT) reduce the dose to organs at risk (OARs) compared to coplanar VMAT, while maintaining the dose to the planning target volume (PTV). This paper seeks to validate this finding with measurements. DCR-VMAT treatment plans were produced for five patients with primary brain tumours and delivered using a commercial linear accelerator (linac). Dosimetric accuracy was assessed using point dose and radiochromic film measurements. Linac-recorded mechanical errors were assessed by extracting deviations from log files for multi-leaf collimator (MLC), couch, and gantry positions every 20 ms. Dose distributions, reconstructed from every fifth log file sample, were calculated and used to determine deviations from the treatment plans. Median (range) treatment delivery times were 125 s (123–133 s) for DCR-VMAT, compared to 78 s (64–130 s) for coplanar VMAT. Absolute point doses were 0.8% (0.6%–1.7%) higher than prediction. For coronal and sagittal films, respectively, 99.2% (96.7%–100%) and 98.1% (92.9%–99.0%) of pixels above a 20% low dose threshold reported gamma
وصف الملف: text
اللغة: English
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::00b12a608860e65a21c3304b68a51bc9Test
https://europepmc.org/articles/PMC6877349Test/
حقوق: OPEN
رقم الانضمام: edsair.pmid.dedup....00b12a608860e65a21c3304b68a51bc9
قاعدة البيانات: OpenAIRE