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1
المؤلفون: Diana Tuskova, James T. Lynch, German Ott, Kevin Hudson, Wolfgang E. Berdel, Myroslav Zapukhlyak, Barry R. Davies, Simon T. Barry, Matthias Pfeifer, Jan Molinsky, Peter Lenz, Michele Mayo, Kristian Erdmann, Michael Grau, Petra Vockova, Pavel Klener, Marek Trneny, Annette M. Staiger, Daniela Schwammbach, Beiying Dai, Tabea Erdmann, Francisco Cruzalegui, Georg Lenz, Urszula M. Polanska, Michael Grondine
المصدر: Blood. 130(3)
مصطلحات موضوعية: 0301 basic medicine, Apoptosis, Pharmacology, Biochemistry, Tyrosine-kinase inhibitor, chemistry.chemical_compound, Mice, Phosphatidylinositol 3-Kinases, 0302 clinical medicine, Piperidines, hemic and lymphatic diseases, Agammaglobulinaemia Tyrosine Kinase, Phosphoinositide-3 Kinase Inhibitors, Oxadiazoles, biology, NF-kappa B, Drug Synergism, Hematology, Protein-Tyrosine Kinases, Gene Expression Regulation, Neoplastic, Drug Combinations, Organ Specificity, 030220 oncology & carcinogenesis, Ibrutinib, Lymphoma, Large B-Cell, Diffuse, Signal transduction, Signal Transduction, medicine.drug_class, Immunology, Antineoplastic Agents, Proto-Oncogene Proteins c-myc, 03 medical and health sciences, medicine, Animals, Humans, Pyrroles, Protein kinase B, Protein Kinase Inhibitors, PI3K/AKT/mTOR pathway, Phosphoinositide 3-kinase, Akt inhibitor AZD5363, Adenine, PTEN Phosphohydrolase, Germinal center, Cell Biology, Xenograft Model Antitumor Assays, 030104 developmental biology, Pyrimidines, chemistry, biology.protein, Cancer research, Pyrazoles, Drug Screening Assays, Antitumor, Proto-Oncogene Proteins c-akt
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15b7729777f360eff7908ecbecbfbd4dTest
https://pubmed.ncbi.nlm.nih.gov/28729335Test -
2
المؤلفون: Sally-Ann Ricketts, Christelle Gendrin, Phillippa Dudley, Barry R. Davies, Juliana Maynard
المصدر: Molecular Imaging and Biology. 15:476-485
مصطلحات موضوعية: Cancer Research, Pathology, medicine.medical_specialty, Time Factors, Mice, Nude, Phases of clinical research, Antineoplastic Agents, Mice, Fluorodeoxyglucose F18, Predictive Value of Tests, Cell Line, Tumor, Biomarkers, Tumor, medicine, Animals, Humans, Pyrroles, Radiology, Nuclear Medicine and imaging, Phosphorylation, Protein Kinase Inhibitors, Protein kinase B, PI3K/AKT/mTOR pathway, Dose-Response Relationship, Drug, medicine.diagnostic_test, Akt inhibitor AZD5363, business.industry, Xenograft Model Antitumor Assays, Tumor Burden, Enzyme Activation, Dose–response relationship, Glucose, Pyrimidines, Treatment Outcome, Oncology, Drug development, Positron emission tomography, Positron-Emission Tomography, Cancer research, Biomarker (medicine), Female, business, Proto-Oncogene Proteins c-akt
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d39c5044cbb3d1886f82bafb10e70d8Test
https://doi.org/10.1007/s11307-013-0613-3Test -
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المؤلفون: Hannah Greenwood, Jingchuan Zhang, Jing Li, Rebecca Watson, Juliana Maynard, James W.T. Yates, Claire Crafter, Beirong Gao, Sally-Ann Ricketts, Darren Cross, Martin Pass, Clare Lane, Christine M. Chresta, Barry R. Davies, Sabina Cosulich, Ken M Page, Philippa Dudley, Qunsheng Ji, Richard W. A. Luke, De-Hua Yu, Donald J. Ogilvie
المصدر: Molecular Cancer Therapeutics. 11:873-887
مصطلحات موضوعية: Male, Cancer Research, Mice, Nude, Breast Neoplasms, Mice, SCID, Pharmacology, Lapatinib, Mice, chemistry.chemical_compound, Trastuzumab, Cell Line, Tumor, medicine, Animals, Humans, Potency, PTEN, Pyrroles, Protein kinase B, Cell Proliferation, biology, Akt inhibitor AZD5363, Prostatic Neoplasms, Xenograft Model Antitumor Assays, Pyrimidines, Oncology, chemistry, Docetaxel, biology.protein, Female, Growth inhibition, Proto-Oncogene Proteins c-akt, Signal Transduction, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e98875526525d3b19c1c9f1c3c90aab9Test
https://doi.org/10.1158/1535-7163.mct-11-0824-tTest -
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المؤلفون: Emma Jenkins, Neil H. James, Justin P.O. Lindemann, Vivien Jacobs, Makoto Kodaira, Brendon Ladd, Nin Guan, Philippa Dudley, Claire Crafter, Kelly Jacques, Kenji Tamura, Michael Zinda, Lyndsey Hanson, Barry R. Davies, Armelle Logie, Celina M. D'Cruz
المصدر: Molecular cancer therapeutics. 14(11)
مصطلحات موضوعية: Male, Cancer Research, Blotting, Western, Mutation, Missense, AKT1, Mice, Nude, Biology, medicine.disease_cause, Cell Line, chemistry.chemical_compound, Breast cancer, Cell Line, Tumor, Neoplasms, Antineoplastic Combined Chemotherapy Protocols, medicine, Animals, Humans, Pyrroles, Phosphorylation, Protein kinase B, Cell Proliferation, Mutation, Akt inhibitor AZD5363, FGFR Inhibitor AZD4547, medicine.disease, Molecular biology, Xenograft Model Antitumor Assays, Pyrimidines, Oncology, chemistry, Doxycycline, embryonic structures, Female, Growth inhibition, Ovarian cancer, Heterocyclic Compounds, 3-Ring, Proto-Oncogene Proteins c-akt, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50972a63abd1b6d424587455bbadeedcTest
https://pubmed.ncbi.nlm.nih.gov/26351323Test -
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المؤلفون: Jan Trapman, Corrina M.A. de Ridder, Rebecca Ellston, Ashraf Aghai, Rute B. Marques, Wytske M. van Weerden, Debra Stuurman, Simon T. Barry, Sander Hoeben, Agnes Boer, Barry R. Davies
المساهمون: Urology, Erasmus MC other, Pathology
المصدر: European Urology, 67(6), 1177-1185. Elsevier
مصطلحات موضوعية: Male, medicine.medical_specialty, Combination therapy, Urology, TMPRSS2, Prostate cancer, SDG 3 - Good Health and Well-being, Cell Line, Tumor, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, PTEN, Pyrroles, Castration, Protein kinase B, PI3K/AKT/mTOR pathway, Cell Proliferation, Phosphoinositide-3 Kinase Inhibitors, Aniline Compounds, Akt inhibitor AZD5363, biology, business.industry, PTEN Phosphohydrolase, Prostatic Neoplasms, medicine.disease, Xenograft Model Antitumor Assays, Androgen receptor, Pyrimidines, Treatment Outcome, Endocrinology, Chromones, Receptors, Androgen, Cancer research, biology.protein, business, Proto-Oncogene Proteins c-akt, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd6de216ec9fabd4915e804bff99f341Test
https://pure.eur.nl/en/publications/a16d5e4a-16b7-4da1-bf21-0c7f2f297896Test -
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المؤلفون: David C. Linch, Rob S. Sellar, Rosemary E. Gale, Asim Khwaja, Dennis Huszar, Koremu Meja, Chloe Stengel, Barry R. Davies
المصدر: British journal of haematology. 167(1)
مصطلحات موضوعية: Adult, Myeloid, Adolescent, Cell Survival, PIM1, Gene Expression, Antineoplastic Agents, Young Adult, Proto-Oncogene Proteins c-pim-1, hemic and lymphatic diseases, Cell Line, Tumor, medicine, Humans, Protein kinase B, Protein Kinase Inhibitors, PI3K/AKT/mTOR pathway, Aged, Cell Proliferation, Phosphoinositide 3-kinase, biology, Akt inhibitor AZD5363, Dose-Response Relationship, Drug, Cell growth, Kinase, TOR Serine-Threonine Kinases, Drug Synergism, Hematology, Middle Aged, Leukemia, Myeloid, Acute, medicine.anatomical_structure, Immunology, Mutation, biology.protein, Cancer research, Myeloid Cell Leukemia Sequence 1 Protein, Proto-Oncogene Proteins c-akt, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bceaeb93410fbf5ff563486e16472ae3Test
https://pubmed.ncbi.nlm.nih.gov/24975213Test -
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المؤلفون: De-Hua Yu, Sufang Han, Barry R. Davies, Xiaolu Yin, Yuan Jie Liu, Jingchuan Zhang, Jing Li, Qunsheng Ji, Huiying Wang, Lily Tang, Yu Bai, Minhua Zhou, Yan Xu
المصدر: Journal of Translational Medicine
مصطلحات موضوعية: China, Mutant, Mice, Nude, Antineoplastic Agents, Docetaxel, Biology, medicine.disease_cause, General Biochemistry, Genetics and Molecular Biology, Receptor tyrosine kinase, Mice, Asian People, Stomach Neoplasms, Cell Line, Tumor, Antineoplastic Combined Chemotherapy Protocols, medicine, PTEN, Animals, Humans, Pyrroles, Protein kinase B, Protein Kinase Inhibitors, PI3K/AKT/mTOR pathway, Cell Proliferation, Medicine(all), Mutation, Akt inhibitor AZD5363, Biochemistry, Genetics and Molecular Biology(all), Research, PTEN Phosphohydrolase, Cancer, Nuclear Proteins, General Medicine, medicine.disease, Molecular biology, Immunohistochemistry, Xenograft Model Antitumor Assays, Disease Models, Animal, Pyrimidines, Treatment Outcome, biology.protein, Female, Taxoids, Proto-Oncogene Proteins c-akt, Transcription Factors
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd1427e688ec41a9aa65b4e02b85f6beTest
https://pubmed.ncbi.nlm.nih.gov/24088382Test -
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المؤلفون: Claire Crafter, Francois Lamoureux, Fan Zhang, Martin E. Gleave, Amina Zoubeidi, Christian Thomas, Masafumi Kumano, Barry R. Davies
المصدر: Clinical cancer research : an official journal of the American Association for Cancer Research. 19(4)
مصطلحات موضوعية: Male, Cancer Research, Programmed cell death, Pharmacology, DU145, Cell Line, Tumor, Autophagy, PTEN, Humans, Pyrroles, Protein kinase B, PI3K/AKT/mTOR pathway, Cell Proliferation, Phosphoinositide 3-kinase, biology, Akt inhibitor AZD5363, Cell Cycle, PTEN Phosphohydrolase, Prostatic Neoplasms, Chloroquine, Drug Synergism, Oncogene Protein v-akt, Pyrimidines, Oncology, Tumor progression, Drug Resistance, Neoplasm, biology.protein, Lysosomes, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9e842b39c3b3cd4dddd4473ab7aaed5Test
https://pubmed.ncbi.nlm.nih.gov/23258740Test -
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المؤلفون: Duncan Forster, Brian A. Telfer, Barry R. Davies, Kaye J. Williams, Ian J. Stratford, Timothy M Illidge, E. Searle
المصدر: Cancer Research. 76:3042-3042
مصطلحات موضوعية: Cancer Research, Pathology, medicine.medical_specialty, Akt inhibitor AZD5363, business.industry, medicine.medical_treatment, Head and neck cancer, Cancer, medicine.disease, Tumor control, Atp competitive, Radiation therapy, Oncology, Cancer research, Medicine, Radiosensitivity, business, Protein kinase B
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::24ba33cf8c8defe53757567e7ed420eeTest
https://doi.org/10.1158/1538-7445.am2016-3042Test -
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المؤلفون: Brian A. Telfer, Timothy M Illidge, Duncan Forster, Ian J. Stratford, Barry R. Davies, Kaye J. Williams, E. Searle
المصدر: Searle, E, Telfer, B, Forster, D, Davies, B R, Stratford, I, Illidge, T & Williams, K 2016, ' Treatment with the novel Akt inhibitor AZD5363 following radiotherapy improves tumour control in mouse models of head and neck cancer ', European Journal of Cancer, vol. 61, no. Supplement 1, pp. S162 . https://doi.org/10.1016/S0959-8049Test(16)61573-3
مصطلحات موضوعية: Oncology, Cancer Research, medicine.medical_specialty, Manchester Cancer Research Centre, Akt inhibitor AZD5363, business.industry, ResearchInstitutes_Networks_Beacons/mcrc, medicine.medical_treatment, Head and neck cancer, medicine.disease, Radiation therapy, Internal medicine, medicine, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dea2387ff82b01626f314c058b8f7550Test
https://doi.org/10.1016/s0959-8049Test(16)61573-3