دورية أكاديمية
The Urban-Rural Gradient In Asthma: A Population-Based Study in Northern Europe.
| العنوان: | The Urban-Rural Gradient In Asthma: A Population-Based Study in Northern Europe. |
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| المؤلفون: | Timm, Signe, Frydenberg, Morten, Janson, Christer, Campbell, Brittany, Forsberg, Bertil, Gislason, Thorarinn, Holm, Mathias, Jogi, Rain, Omenaas, Ernst, Sigsgaard, Torben, Svanes, Cecilie, Schlünssen, Vivi |
| المساهمون: | 1 Aarhus Univ, Danish Ramazzini Ctr, Dept Publ Hlth, DK-8000 Aarhus C, Denmark 2 Uppsala Univ, Dept Med Sci Resp Allergy & Sleep Res, S-75105 Uppsala, Sweden 3 Univ Melbourne, Melbourne Sch Populat & Global Hlth, Ctr Epidemiol & Biostat, Allergy & Lung Hlth Unit, Melbourne, Vic 3010, Australia 4 Umea Univ, Dept Publ Hlth & Clin Med, Div Occupat & Environm Med, S-90187 Umea, Sweden 5 Landspitali Univ Hosp, Dept Resp Med & Sleep, IS-108 Reykjavik, Iceland Organization-Enhanced Name(s) Landspitali National University Hospital 6 Univ Iceland, Fac Med, IS-101 Reykjavik, Iceland 7 Sahlgrens Univ Hosp, Dept Occupat & Environm Med, S-40530 Gothenburg, Sweden 8 Tartu Univ Hosp, Lung Clin, EE-50406 Tartu, Estonia 9 Univ Bergen, Inst Clin Sci, N-5020 Bergen, Norway 10 Natl Res Ctr Working Environm, DK-2100 Copenhagen, Denmark |
| بيانات النشر: | MDPI AG |
| سنة النشر: | 2016 |
| المجموعة: | Hirsla - Landspítali University Hospital research archive |
| مصطلحات موضوعية: | Asma, Umhverfisáhrif, Tíðni, Áhættuþættir, PAD12, Adult, Asthma, Cross-Sectional Studies, Europe, Female, Health Surveys, Humans, Incidence, Male, Middle Aged, Prevalence, Proportional Hazards Models, Protective Factors, Residence Characteristics, Risk Factors, Rural Health, Surveys and Questionnaires, Urban Health |
| الوصف: | To access publisher's full text version of this article, please click on the hyperlink in Additional Links field or click on the hyperlink at the top of the page marked Files. This article is open access. ; The early life environment appears to have a persistent impact on asthma risk. We hypothesize that environmental factors related to rural life mediate lower asthma prevalence in rural populations, and aimed to investigate an urban-rural gradient, assessed by place of upbringing, for asthma. The population-based Respiratory Health In Northern Europe (RHINE) study includes subjects from Denmark, Norway, Sweden, Iceland and Estonia born 1945-1973. The present analysis encompasses questionnaire data on 11,123 RHINE subjects. Six categories of place of upbringing were defined: farm with livestock, farm without livestock, village in rural area, small town, city suburb and inner city. The association of place of upbringing with asthma onset was analysed with Cox regression adjusted for relevant confounders. Subjects growing up on livestock farms had less asthma (8%) than subjects growing up in inner cities (11%) (hazard ratio 0.72 95% CI 0.57-0.91), and a significant urban-rural gradient was observed across six urbanisation levels (p = 0.02). An urban-rural gradient was only evident among women, smokers and for late-onset asthma. Analyses on wheeze and place of upbringing revealed similar results. In conclusion, this study suggests a protective effect of livestock farm upbringing on asthma development and an urban-rural gradient in a Northern European population. ; Faculty of Health, Aarhus University, Denmark 240008 Wood Dust Foundation 444508795 Danish Lung Association Swedish Heart and Lung Foundation Swedish Association Against Asthma and Allergy Swedish Association against Heart and Lung Disease Swedish Council for Working Life and Social Research Bror Hjerpstedt Foundation Vardal Foundation for Health Care and Allergic Researce Norwegian Research Council 135773/330 Norwegian Asthma and Allergy Association ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 1660-4601 |
| العلاقة: | http://dx.doi.orgTest/ 10.3390/ijerph13010093; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730484Test/; The Urban-Rural Gradient In Asthma: A Population-Based Study in Northern Europe. 2016, 13 (1):93 Int J Environ Res Public Health; http://hdl.handle.net/2336/618525Test; International journal of environmental research and public health |
| DOI: | 10.3390/ijerph13010093 |
| الإتاحة: | https://doi.org/10.3390/ijerph13010093Test http://hdl.handle.net/2336/618525Test |
| حقوق: | Archived with thanks to International journal of environmental research and public health ; Open Access |
| رقم الانضمام: | edsbas.E76CBF87 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 16604601 |
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| DOI: | 10.3390/ijerph13010093 |