المؤلفون: M. Aiman Mohtar, Reynald Gillet, Daniel Thomas, Pierre-Jean Le Reste, Federica G. Centonze, Sophie Chat, Ted R. Hupp, Luc Negroni, Aeid Igbaria, Raphael Pineau, Daria Sicari, Eric Chevet

المساهمون: Chemistry, Oncogenesis, Stress and Signaling (COSS), Université de Rennes (UR)-CRLCC Eugène Marquis (CRLCC)-Institut National de la Santé et de la Recherche Médicale (INSERM), CRLCC Eugène Marquis (CRLCC), CHU Pontchaillou [Rennes], Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Institut de Génétique et Développement de Rennes (IGDR), Université de Rennes (UR)-Centre National de la Recherche Scientifique (CNRS)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), University of Edinburgh, Ben-Gurion University of the Negev (BGU), This work was funded by grants from Institut National de la Santé et de la Recherche Médicale (INSERM‐U1242), Institut National du Cancer (INCa, PLBIO18, PLBIO19, PLBIO20), Fondation pour la Recherche Médicale (FRM, équipe labellisée 2018, DEQ20180339169), Agence National de la Recherche (ANR, ERANET ERAAT), MSCA RISE‐734749 (INSPIRED), Cancéropôle Grand Ouest (Gliotreat) grants to EC, the BBSRC UK (EM, BB/C511599/1, and BB/J00751X/1) and UKM Fellowship and Ministry of Higher Education (MOHE) of Malaysia KPT(BS)870809015063 (MAM). DS was supported by an AIRC #22319 fellowship for abroad., ANR-17-RAR3-0003,ERAAT,Enhancing Endoplasmic Reticulum Proteostasis to Rescue Alpha1 Antitrypsin Deficiency(2017), Institut National de la Santé et de la Recherche Médicale (INSERM)-CRLCC Eugène Marquis (CRLCC)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES), Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )-Centre National de la Recherche Scientifique (CNRS)-Université de Rennes 1 (UR1), HAL UR1, Admin, Enhancing Endoplasmic Reticulum Proteostasis to Rescue Alpha1 Antitrypsin Deficiency - - ERAAT2017 - ANR-17-RAR3-0003 - E-RARE - VALID

المصدر: EMBO Reports
EMBO Reports, 2021, 22 (5), pp.e51412. ⟨10.15252/embr.202051412⟩
EMBO Reports, EMBO Press, 2021, 22 (5), pp.e51412. ⟨10.15252/embr.202051412⟩
Sicari, D, Centronze, F G, Pineau, R, Le Reste, P-J, Negroni, L, Chat, S, Mohtar, M A, Thomas, D, Gillet, R, Hupp, T R, Chevet, E & Igbaria, A 2021, ' Reflux of Endoplasmic Reticulum proteins to the cytosol inactivates tumor suppressors ', EMBO Reports . https://doi.org/10.15252/embr.202051412Test

مصطلحات موضوعية: AGR2, [SDV.CAN]Life Sciences [q-bio]/Cancer, Endoplasmic-reticulum-associated protein degradation, Biochemistry, Article, law.invention, 03 medical and health sciences, Mice, 0302 clinical medicine, Cytosol, [SDV.CAN] Life Sciences [q-bio]/Cancer, law, Genetics, Selective advantage, [SDV.BBM] Life Sciences [q-bio]/Biochemistry, Molecular Biology, Animals, cancer, Translation & Protein Quality, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, Molecular Biology, 030304 developmental biology, Organelles, 0303 health sciences, Chemistry, Endoplasmic reticulum, Proteins, Endoplasmic Reticulum-Associated Degradation, Articles, ERAD, Endoplasmic Reticulum Stress, 3. Good health, Cell biology, endoplasmic reticulum, Proteostasis, Unfolded protein response, Suppressor, reflux, ER stress, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c16e1dca854f240c2c0540dbaec04d47Test
https://hal.science/hal-03194503Test

المؤلفون: Daniel Thomas, Reynald Gillet, M. Aiman Mohtar, Daria Sicari, Sophie Chat, Luc Negroni, M. Ted Hupp, Raphael Pineau, Pierre-Jean Le Reste, Aeid Igbaria, Eric Chevet

مصطلحات موضوعية: 0303 health sciences, Chemistry, Endoplasmic reticulum, AGR2, Tumor cells, medicine.disease, Cell biology, law.invention, 03 medical and health sciences, Cytosol, 0302 clinical medicine, Proteostasis, law, 030220 oncology & carcinogenesis, medicine, Selective advantage, Suppressor, 030304 developmental biology, Glioblastoma

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::729a360cf526c80237de80d16cc95f2cTest
https://doi.org/10.1101/2020.04.13.038935Test