المؤلفون: Leino, Teppo O., Turku, Ainoleena, Urvas, Lauri, Adhikari, Karuna, Oksanen, Jouni, Steynen, Yana, Yli-Kauhaluoma, Jari, Xhaard, Henri, Kukkonen, Jyrki P., Wallén, Erik A. A.

المساهمون: Divisions of Faculty of Pharmacy, Division of Pharmaceutical Chemistry and Technology, Drug Research Program, Pharmaceutical Design and Discovery group, Veterinary Biosciences, Faculty of Veterinary Medicine, Faculty of Pharmacy, Department of Pharmacology, Jari Yli-Kauhaluoma / Principal Investigator, Computational Adme, Henri Xhaard / Principal Investigator, Division of Pharmaceutical Biosciences, Erik Wallen / Principal Investigator, Medicinal Chemistry research group

مصطلحات موضوعية: Agonist, Azulene, Medicinal chemistry, Orexin receptor, Sulfonamides, 3111 Biomedicine, 1182 Biochemistry, cell and molecular biology, 317 Pharmacy

وصف الملف: application/pdf

العلاقة: Leino , T O , Turku , A , Urvas , L , Adhikari , K , Oksanen , J , Steynen , Y , Yli-Kauhaluoma , J , Xhaard , H , Kukkonen , J P & Wallén , E A A 2023 , ' Azulene as a biphenyl mimetic in orexin/hypocretin receptor agonists ' , Bioorganic & Medicinal Chemistry , vol. 88-89 , 117325 . https://doi.org/10.1016/j.bmc.2023.117325Test; ORCID: /0000-0002-6989-1564/work/137437590; ORCID: /0000-0003-0370-7653/work/137437764; ORCID: /0000-0003-0959-7221/work/137438818; ORCID: /0000-0003-2582-7971/work/137440251; http://hdl.handle.net/10138/359559Test; c9572f10-7a1b-42fd-9f32-fe162591a425; 001001557400001

الإتاحة: http://hdl.handle.net/10138/359559Test

المؤلفون: Leino, Teppo O., Turku, Ainoleena, Yli-Kauhaluoma, Jari Tapani, Kukkonen, Jyrki P., Xhaard, Henri, Wallén, Erik A. A.

المساهمون: Faculty of Pharmacy, Pharmaceutical Design and Discovery group, Division of Pharmaceutical Chemistry and Technology, Drug Research Program, Jari Yli-Kauhaluoma / Principal Investigator, Jyrki Kukkonen / Principal Investigator, Veterinary Biochemistry and Cell Biology, Veterinary Biosciences, Departments of Faculty of Veterinary Medicine, Faculty of Veterinary Medicine, Department of Physiology, Medicum, Henri Xhaard / Principal Investigator, Erik Wallen / Principal Investigator, Medicinal Chemistry research group

مصطلحات موضوعية: 317 Pharmacy, 116 Chemical sciences, Azulene, Orexin receptor, Potentiator, Agonist, Antagonist, Sleep-wake regulation, PROTEIN-COUPLED RECEPTORS, HAMSTER OVARY CELLS, SIGNAL-TRANSDUCTION, CA2+ INFLUX, OX1, DERIVATIVES, INHIBITORS, PEPTIDES, LIGANDS, KINASE

وصف الملف: application/pdf

العلاقة: Leino , T O , Turku , A , Yli-Kauhaluoma , J T , Kukkonen , J P , Xhaard , H & Wallén , E A A 2018 , ' Azulene-based compounds for targeting orexin receptors ' , European Journal of Medicinal Chemistry , vol. 157 , pp. 88-100 . https://doi.org/10.1016/j.ejmech.2018.07.040Test; ORCID: /0000-0003-0370-7653/work/50286680; ORCID: /0000-0003-0959-7221/work/50289879; ORCID: /0000-0003-2582-7971/work/50290708; ORCID: /0000-0002-6989-1564/work/63349244; http://hdl.handle.net/10138/319069Test; be64b9c4-f27c-4b99-9902-88569234386b; 85050849346; 000447480000008

الإتاحة: http://hdl.handle.net/10138/319069Test

المؤلفون: Leino, Teppo O.¹ teppo.leino@helsinki.fi, Turku, Ainoleena^1,2, Yli-Kauhaluoma, Jari¹, Kukkonen, Jyrki P.^2,3, Xhaard, Henri¹, Wallén, Erik A.A.¹

المصدر: European Journal of Medicinal Chemistry. Sep2018, Vol. 157, p88-100. 13p.

مصطلحات موضوعية: *AZULENE, *OREXINS, *ORGANIC synthesis, *SLEEP-wake cycle, *CHEMICAL derivatives