دورية أكاديمية

Alteration in flow (shear stress)-induced remodelling in rat resistance arteries with aging: improvement by a treatment with hydralazine.

التفاصيل البيبلوغرافية
العنوان: Alteration in flow (shear stress)-induced remodelling in rat resistance arteries with aging: improvement by a treatment with hydralazine.
المؤلفون: Dumont, Odile, Pinaud, Frederic, Guihot, Anne-Laure, Baufreton, Christophe, Loufrani, Laurent, Henrion, Daniel
المصدر: Cardiovascular Research; Feb2008, Vol. 77 Issue 3, p600-608, 9p, 6 Graphs
مصطلحات موضوعية: VASCULAR diseases, AGING, HYDRALAZINE, LABORATORY rats, BLOOD flow
مستخلص: Aims: The link between aging and vascular diseases remains unclear, especially in resistance arteries. As a decreased vasodilator capacity of the endothelium is usually described in aging, we hypothesized that arteriolar remodelling in response to a chronic increase in blood flow might be altered. In addition, we tested the capacity of a vasodilator treatment with hydralazine to restore remodelling, as we have previously shown that hydralazine has a potent effect on the process. [ABSTRACT FROM PUBLISHER]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:00086363
DOI:10.1093/cvr/cvm055