| المؤلفون: |
Jonathan Kjær Grønbæk, Morten Wibroe, Sebastian Toescu, Radek Frič, Birthe Lykke Thomsen, Lisbeth Nørgaard Møller, Pernilla Grillner, Bengt Gustavsson, Conor Mallucci, Kristian Aquilina, Greg Adam Fellows, Emanuela Molinari, Magnus Aasved Hjort, Mia Westerholm-Ormio, Rosita Kiudeliene, Katalin Mudra, Peter Hauser, Kirsten van Baarsen, Eelco Hoving, Julian Zipfel, Karsten Nysom, Kjeld Schmiegelow, Astrid Sehested, Marianne Juhler, René Mathiasen, Mimi Kjærsgaard, Lars Bøgeskov, Jane Skjøth-Rasmussen, John Hauerberg Tamm, Lars Poulsgaard, Thora Gudrunardottir, Sylvester Kløcker Grønbæk, Alberte Blichfeldt, Felix Nicolai Raben-Levetzau, Michael Thude Callesen, Mathias Rathe, Rikke Bassø Klokker, Gorm von Oettingen, Torben Mikkelsen, Louise Tram Henriksen, Søren Cortnum, Kamilla Tofting-Olesen, Atte Karppinen, Kristin Solem, Ingrid Kristin Torsvik, Ann-Karin Mosand, Line Rapp Simonsen, Christoffer Ehrstedt, Ingela Kristiansen, Karin Fritzson, Line Balestrand Haga, Hege Kristine Fagerholt, Helene Stømqvist Blixt, Hanna Sundgren, Yvonne Håkansson, Charlotte Castor, Per Nyman, Anne Wretman, Pelle Nilsson, Ann-Christin Bjørklund, Magnus Sabel, Inga-Lill Haij, Frans Nilsson, Hanna Olausson, Claire Cummings, Jade Flemming, Deborah Afolabi, Kim Phipps, Ian Kamaly, Sharon Williams, Noor-ul-Owase Jeelani, Donald McArthur, Elisabeth Wiles, David Walker, Rebecca Cooper, Greg Fellows, Lizzy Hoole, Kirsty Slater, Jothy Kandasamy, Rachel McAndrew, Katie McLaughlin, Martin Schumann, Shivaram Avula, Barry Pizer, Giedre Rutkauskiene, Algimantas Matukevicius, Leonie van den Abbeele, Balázs Markia, Beatrix Pálmafy, Niels Clausen, Karen Margrethe Ottosen Møller, Harald Thomassen, Johan Cappelen, Einar Stensvold, Irene Devennay, Tuula Lønnqvist, Kristiina Nordfors, Päivi Lähteenmäki |
| المصدر: |
Grønbæk, J K, Wibroe, M, Toescu, S, Frič, R, Thomsen, B L, Møller, L N, Grillner, P, Gustavsson, B, Mallucci, C, Aquilina, K, Fellows, G A, Molinari, E, Hjort, M A, Westerholm-Ormio, M, Kiudeliene, R, Mudra, K, Hauser, P, van Baarsen, K, Hoving, E, Zipfel, J, Nysom, K, Schmiegelow, K, Sehested, A, Juhler, M, Mathiasen, R & CMS study group 2021, ' Postoperative speech impairment and surgical approach to posterior fossa tumours in children : a prospective European multicentre cohort study ', The Lancet Child & Adolecent Health, vol. 5, no. 11, pp. 814-824 . https://doi.org/10.1016/S2352-4642Test(21)00274-1 |
| الوصف: |
BACKGROUND: Brain tumours are the most common solid tumours in childhood. Half of these tumours occur in the posterior fossa, where surgical removal is complicated by the risk of cerebellar mutism syndrome, of which postoperative speech impairment (POSI) is a cardinal symptom, in up to 25% of patients. The surgical approach to midline tumours, mostly undertaken by transvermian or telovelar routes, has been proposed to influence the risk of POSI. We aimed to investigate the risk of developing POSI, the time course of its resolution, and its association with surgical approach and other clinical factors. METHODS: In this observational prospective multicentre cohort study, we included children (aged |
