التفاصيل البيبلوغرافية
| العنوان: |
Psychosocial Effects of Vitiligo: A Systematic Literature Review. |
| المؤلفون: |
Ezzedine, Khaled1 khaled.ezzedine@aphp.fr, Eleftheriadou, Viktoria2, Jones, Heather3, Bibeau, Kristen3, Kuo, Fiona I.3, Sturm, Daniel3, Pandya, Amit G.4,5 |
| المصدر: |
American Journal of Clinical Dermatology. Nov2021, Vol. 22 Issue 6, p757-774. 18p. |
| مصطلحات موضوعية: |
*ONLINE information services, *MEDICAL information storage & retrieval systems, *MEDICAL databases, *INFORMATION storage & retrieval systems, *SYSTEMATIC reviews, *AGE distribution, *BURDEN of care, *SOCIAL stigma, *ATTITUDES toward illness, *SLEEP disorders, *AVOIDANCE (Psychology), *SEX distribution, *BODY surface area, *QUALITY of life, *MENTAL depression, *DESCRIPTIVE statistics, *PSYCHOLOGY of the sick, *PSYCHOLOGICAL adaptation, *MEDLINE, *ANXIETY, *VITILIGO, *COMORBIDITY, *ADJUSTMENT disorders |
| مستخلص: |
Background: Patients with vitiligo experience reduced quality of life. Objective: To comprehensively describe the available evidence for psychosocial burden in vitiligo. Methods: A systematic review of observational studies and clinical trials identified using PubMed, EMBASE, Scopus, and the Cochrane databases was performed through 1 March, 2021, to assess psychosocial comorbidities in vitiligo. Two independent reviewers performed an assessment of articles and extracted data for qualitative synthesis. Results: Included studies (N = 168) were published between 1979 and 1 March, 2021; 72.6% were published since 2010. Disorders including or related to depression (41 studies, 0.1–62.3%) and anxiety (20 studies, 1.9–67.9%) were the most commonly reported. The most prevalent psychosocial comorbidities were feelings of stigmatization (eight studies, 17.3–100%), adjustment disorders (12 studies, 4–93.9%), sleep disturbance (seven studies, 4.6–89.0%), relationship difficulties including sexual dysfunction (ten studies, 2.0–81.8%), and avoidance or restriction behavior (12.5–76%). The prevalence of most psychosocial comorbidities was significantly higher vs healthy individuals. Factors associated with a significantly higher burden included female sex, visible or genital lesions, age < 30 years (particularly adolescents), and greater body surface area involvement, among others. The most commonly reported patient coping strategy was lesion concealment. Limitations: Available studies were heterogeneous and often had limited details; additionally, publication bias is possible. Conclusions: The results of this systematic review show that vitiligo greatly affects psychosocial well-being. The extent of psychosocial comorbidities supports the use of multidisciplinary treatment strategies and education to address the vitiligo-associated burden of disease. Protocol Registration: PROSPERO (CRD42020162223). [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
Academic Search Index |
