المؤلفون: Adolfo Correa, Jai G. Broome, Chunyan Ren, Kari E. North, Nancy L. Heard-Costa, Yao Yao, Brian D. Hobbs, Mary Cushman, Leslie A. Lange, Daniel E. Bauer, Xiuwen Zheng, Braxton D. Mitchell, Yun Li, Quan Sun, Sébastian Méric de Bellefon, Terri H. Beaty, Paul S. de Vries, Ruth J. F. Loos, Adrienne M. Stilp, Albert V. Smith, Paul L. Auer, Deepti Jain, Lifang Hou, Robert C. Kaplan, Jee-Young Moon, Michael Preuss, Stephen S. Rich, Guillaume Lettre, Nicole Soranzo, Eric Boerwinkle, Kousik Kundu, Laura Almasy, Marsha M. Wheeler, Thomas W. Blackwell, Nancy Min, Nicholas L. Smith, Bruce M. Psaty, Lisa R. Yanek, Joanne E. Curran, Stacey Gabriel, Kathleen A. Ryan, Alanna C. Morrison, Lynette Ekunwe, Caitlin P. McHugh, Laura M. Raffield, Adam S. Butterworth, Deborah A. Nickerson, Ravindranath Duggirala, Gonçalo R. Abecasis, John Lane, Hélène Choquet, Andrew D. Johnson, Nauder Faraday, Russell T. Walton, Praveen Surendran, Jennifer A. Brody, Yao Hu, Alexander P. Reiner, Jerome I. Rotter, Donald M. Lloyd-Jones, Cathy C. Laurie, Zhe Wang, Hua Tang, Charles Kooperberg, Eric Jorgenson, Jeffrey R. O'Connell, Shuquan Rao, Nathalie Chami, Rasika A. Mathias, Matthew P. Conomos, Myriam Fornage, Ramachandran S. Vasan, Nathan Pankratz, Joshua P. Lewis, Lewis C. Becker, Benjamin P. Kleinstiver, Cecelia A. Laurie, Ming-Huei Chen, John Blangero

المصدر: Am J Hum Genet

مصطلحات موضوعية: Adult, Male, Quality Control, 0301 basic medicine, Erythrocytes, Population, Datasets as Topic, Genome-wide association study, Biology, Quantitative trait locus, Article, 03 medical and health sciences, 0302 clinical medicine, Genetics, Humans, Indel, education, Gene, Genetics (clinical), Aged, Genetic association, Gene Editing, Whole genome sequencing, education.field_of_study, Genetic Variation, Reproducibility of Results, Correction, Middle Aged, United States, Genetic architecture, HEK293 Cells, Phenotype, 030104 developmental biology, 030220 oncology & carcinogenesis, Female, National Heart, Lung, and Blood Institute (U.S.), Chromosomes, Human, Pair 16, Genome-Wide Association Study

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b87edb710dac1b94b0361a1b7107d06Test
https://doi.org/10.1016/j.ajhg.2021.04.003Test

المؤلفون: Melissa E. Garcia, Majken K. Jensen, Margaux F. Keller, Joachim H. Ix, Richard A. Jensen, Vasan S. Ramachandran, Jie Yao, Kenneth J. Mukamal, Anne B. Newman, Tamara B. Harris, Frank B. Hu, Ming-Huei Chen, Jorge R. Kizer, Bruce M. Psaty, Alice M. Arnold, James S. Pankow, Jerome I. Rotter, Ronit Katz, Luc Djoussé, David S. Siscovick, Xiuqing Guo, Mike A. Nalls, Ida Chen, Yongmei Liu, Ron C. Hoogeveen, Qi Sun, Eric B. Rimm, Mark O. Goodarzi, Marilyn C. Cornelis, Joseph M. Zmuda, Kathryn M. Rexrode

المصدر: Human molecular genetics, vol 26, iss 11

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Genotype, alpha-2-HS-Glycoprotein, Population, 030209 endocrinology & metabolism, Locus (genetics), Single-nucleotide polymorphism, Genome-wide association study, Biology, Polymorphism, Single Nucleotide, Medical and Health Sciences, White People, 03 medical and health sciences, Exon, 0302 clinical medicine, Diabetes Mellitus, Genetics, Humans, 2.1 Biological and endogenous factors, SNP, Polymorphism, Aetiology, education, Molecular Biology, Gene, Metabolic and endocrine, Genetics (clinical), Aged, Metabolic Syndrome, Genetics & Heredity, education.field_of_study, Association Studies Articles, Human Genome, Single Nucleotide, General Medicine, Middle Aged, Biological Sciences, Black or African American, 030104 developmental biology, Diabetes Mellitus, Type 2, Genetic Loci, Female, Type 2, Genome-Wide Association Study

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fb5b598bf38b9e518ce5be416e1c53fTest
https://doi.org/10.1093/hmg/ddx091Test

المؤلفون: Nauder Faraday, Lisa R. Yanek, Richard A. Gibbs, Narayanan Veeraraghavan, Rasika A. Mathias, John D. Eicher, Lewis C. Becker, Eric Boerwinkle, Jennifer A. Brody, Honghuang Lin, Donna M. Muzny, L. Adrienne Cupples, Ginger A. Metcalf, Andrew D. Johnson, Diane M. Becker, Achilleas N. Pitsillides, Ming-Huei Chen

المصدر: Thrombosis and Haemostasis. 117:1083-1092

مصطلحات موضوعية: Adult, Blood Platelets, Male, 0301 basic medicine, Epinephrine, Genotype, Platelet Aggregation, Population, Hyaluronoglucosaminidase, Disease, Gene mutation, GSTZ1, Biology, GPI-Linked Proteins, Cohort Studies, 03 medical and health sciences, Framingham Heart Study, Population Groups, Exome Sequencing, Humans, Missense mutation, Exome, education, Gene, Alleles, Exome sequencing, Genetics, education.field_of_study, Polymorphism, Genetic, Membrane Proteins, Hematology, Middle Aged, Phosphoproteins, Adenosine Diphosphate, Protein Transport, 030104 developmental biology, Massachusetts, Cardiovascular Diseases, Mutation, Female, Cell Adhesion Molecules

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53a7304d7a29263b018de9266acd175cTest
https://doi.org/10.1160/th16-09-0677Test

المؤلفون: Honghuang Lin, Henry Völzke, Manja Koch, Ming-Huei Chen, Holly M. Smith, Henri Wallaschofski, Radwan Safa, Roberto Lorbeer, Matthias Nauck, Douglas B. Sawyer, Martin G. Larson, Uwe Völker, Alexander Teumer, Wolfgang Lieb, Sebastian E. Baumeister, Ramachandran S. Vasan

المصدر: Circulation: Cardiovascular Genetics. 8:389-397

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Angiogenesis, medicine.medical_treatment, Vesicular Transport Proteins, Genome-wide association study, Biology, Polymorphism, Single Nucleotide, Article, Framingham Heart Study, Neoplasms, Internal medicine, Genetic variation, Genetics, medicine, Humans, Genetic Predisposition to Disease, Genetics (clinical), Models, Genetic, Hepatocyte Growth Factor, Growth factor, Middle Aged, Receptor, TIE-2, Endocrinology, Study of Health in Pomerania, Biomarker (medicine), Female, Hepatocyte growth factor, Cardiology and Cardiovascular Medicine, Genome-Wide Association Study, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::484789f48605af584d677c8ae2b7ec4bTest
https://doi.org/10.1161/circgenetics.114.000597Test

المؤلفون: Arne Schillert, Vanessa Xanthakis, Isabel Bernges, Stefan Blankenberg, Peter J. Grant, Heribert Schunkert, Kathryn L. Lunetta, Lisa M. Sullivan, Anja Kittel, Nicholas L. Smith, Mohammad Arfan Ikram, Philipp S. Wild, Heinrich Sticht, Nicole L. Glazer, Myriam Fornage, Thomas Münzel, Angela M. Carter, Renke Maas, H.-Erich Wichmann, Wolfgang Lieb, Bruce M. Psaty, Kerri L. Wiggins, William T. Longstreth, Thomas Illig, Christina Loley, Ming-Huei Chen, Nicole Lüneburg, Susan R. Heckbert, Jörg König, Andreas Ziegler, Francisco Ojeda, Sudha Seshadri, Thomas J. Wang, Jeanette Erdmann, Tanja Zeller, Ramachandran S. Vasan, Karl J. Lackner, Maike Anderssohn, Edzard Schwedhelm, Inke R. König, Christa Meisinger, Rainer H. Böger, Emelia J. Benjamin, Christian Gieger

المصدر: Circ. Cardiovasc. Genet. 7, 864-872 (2014)

مصطلحات موضوعية: Adult, Male, Genotype, Arginine, Cell, Genome Wide Association Study, Biomarker, Endothelial Function, Nitric Oxide, Genome-wide association study, Polymorphism, Single Nucleotide, Article, Amidohydrolases, Substrate Specificity, Nitric oxide, Cohort Studies, chemistry.chemical_compound, Risk Factors, Genetics, medicine, Humans, Binding site, Transaminases, Genetics (clinical), Aged, Binding Sites, Mediator Complex, biology, HEK 293 cells, Middle Aged, Protein Structure, Tertiary, Stroke, Nitric oxide synthase, Metabolic pathway, HEK293 Cells, medicine.anatomical_structure, chemistry, Biochemistry, Genetic Loci, biology.protein, Female, Cardiology and Cardiovascular Medicine, Genome-Wide Association Study

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e36b3f765d56c0255b25fee73c9970dTest
https://doi.org/10.1161/circgenetics.113.000264Test

المؤلفون: Ching-Yu Cheng, Alexander Teumer, Cristian Pattaro, Peter Vollenweider, Heribert Schunkert, Lenore J. Launer, Reinhold Schmidt, Josef Coresh, Joshua C. Bis, Christopher J. O'Donnell, Stephen T. Turner, W. H. Linda Kao, François Bastardot, Matthias Olden, Rainer Rettig, Conall M. O'Seaghdha, Germaine C. Verwoert, David S. Siscovick, Abbas Dehghan, Myriam Fornage, Ming-Huei Chen, Xueling Sim, Anna Köttgen, Muredach P. Reilly, Caroline S. Fox, Murielle Bochud, Gary F. Mitchell

المساهمون: Epidemiology, CKDGen Consortia, AortaGen CARDIoGRAM CHARGE Eye CHARGE IMT ICBP, NeuroCHARGE

المصدر: American Journal of Kidney Diseases, 61(6), 889-898. W.B. Saunders
American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation, vol. 61, no. 6, pp. 889-898

مصطلحات موضوعية: Adult, Male, Oncology, Pathology, medicine.medical_specialty, Population, Renal function, Blood Pressure, Single-nucleotide polymorphism, Genome-wide association study, Carotid Intima-Media Thickness, Polymorphism, Single Nucleotide, Coronary artery disease, SDG 3 - Good Health and Well-being, Internal medicine, medicine, Humans, Renal Insufficiency, Chronic, education, Adaptor Proteins, Signal Transducing, Aged, education.field_of_study, business.industry, Intracellular Signaling Peptides and Proteins, Proteins, Middle Aged, medicine.disease, Blood pressure, Cardiovascular Diseases, Nephrology, Albuminuria, Female, medicine.symptom, business, Genome-Wide Association Study, Glomerular Filtration Rate, Kidney disease

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8b5e84690406c5c66805d5f2d361019Test
https://doi.org/10.1053/j.ajkd.2012.12.024Test

المؤلفون: Nicole L. Glazer, Cheryl Ingram, John F. Keaney, Vanessa Xanthakis, Christopher J. O'Donnell, Danielle Enserro, David D. McManus, Lisa M. Sullivan, Bernhard M. Kaess, Ramachandran S. Vasan, Ming-Huei Chen

المصدر: The Journal of Clinical Endocrinology & Metabolism. 97:E1943-E1947

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, alpha-2-HS-Glycoprotein, Endocrinology, Diabetes and Metabolism, Clinical Biochemistry, Context (language use), Fatty Acid-Binding Proteins, Biochemistry, Body Mass Index, Endocrinology, Insulin resistance, Framingham Heart Study, Risk Factors, Internal medicine, Diabetes mellitus, medicine, Humans, Sex Distribution, Adiposity, Metabolic Syndrome, Sex Characteristics, Retinol binding protein 4, biology, Biochemistry (medical), JCEM Online: Brief Reports, Middle Aged, medicine.disease, Retinol binding protein, C-Reactive Protein, Massachusetts, Cardiovascular Diseases, Multivariate Analysis, biology.protein, Female, Insulin Resistance, Metabolic syndrome, Retinol-Binding Proteins, Plasma, alpha-2-HS-glycoprotein, Biomarkers

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dff95830e0b2b0a6d9989fb643f14817Test
https://doi.org/10.1210/jc.2012-1458Test

المؤلفون: Joshua C. Bis, Jens Baumert, Bruce M. Psaty, Barbara McKnight, Saonli Basu, Albert Hofman, Kent D. Taylor, Ming-Huei Chen, Maryam Kavousi, Christopher J. O'Donnell, Susana Eyhermendy, Moniek P.M. de Maat, Nicholas L. Smith, David Couper, Andrew D. Johnson, David P. Strachan, Wolfgang Koenig, Gordon D.O. Lowe, Christian Gieger, Wendy L. McArdle, Jacqueline C.M. Witteman, Martin G. Larson, Yurii S. Aulchenko, James S. Pankow, Fernando Rivadeneira, Thomas Lumley, Aaron R. Folsom, Qiong Yang, Eric Boerwinkle, Cornelia M. van Duijn, Weihong Tang, Joseph M. Massaro, Annette Peters, Alicja R Rudnicka, André G. Uitterlinden, Kelly A. Volcik, Thomas Illig, Geoffrey H. Tofler, Abbas Dehghan, Melanie Kolz, Sekar Kathiresan

المساهمون: Epidemiology, Internal Medicine

المصدر: Dehghan, A, Yang, Q, Peters, A, Basu, S, Bis, J C, Rudnicka, A R, Kavousi, M, Chen, M-H, Baumert, J, Lowe, G D O, McKnight, B, Tang, W, de Maat, M, Larson, M G, Eyhermendy, S, McArdle, W L, Lumley, T, Pankow, J S, Hofman, A, Massaro, J M, Rivadeneira, F, Kolz, M, Taylor, K D, van Duijn, C M, Kathiresan, S, Illig, T, Aulchenko, Y S, Volcik, K A, Johnson, A D, Uitterlinden, A G, Tofler, G H, Gieger, C, Psaty, B M, Couper, D J, Boerwinkle, E, Koenig, W, O'Donnell, C J, Witteman, J C, Strachan, D P, Smith, N L, Folsom, A R 2009, ' Association of novel genetic Loci with circulating fibrinogen levels : a genome-wide association study in 6 population-based cohorts ', Circulation: Cardiovascular Genetics, vol. 2, no. 2, pp. 125-33 . https://doi.org/10.1161/CIRCGENETICS.108.825224Test
Circulation-cardiovascular genetics, 2(2), 125-133. Lippincott Williams & Wilkins

مصطلحات موضوعية: Adult, Male, Genome-wide association study, Population based, Biology, Fibrinogen, Polymorphism, Single Nucleotide, White People, Article, Cohort Studies, Young Adult, Fibrinogen levels, Polymorphism (computer science), Genetics, medicine, Humans, Gene, Genetics (clinical), Aged, Aged, 80 and over, Medicine(all), Middle Aged, Pedigree, Coagulation, Cardiovascular Diseases, Genetic Loci, Meta-analysis, Female, Cardiology and Cardiovascular Medicine, Genome-Wide Association Study, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6206afc7b50db90ede0dbebb4febbefTest
https://doi.org/10.1161/circgenetics.108.825224Test

المؤلفون: Riccardo E. Marioni, Christopher J. O'Donnell, Oscar H. Franco, Johan G. Eriksson, Francesco Cucca, Jonathan Marten, Alexander P. Reiner, Tim D. Spector, Philipp S. Wild, Paul Mitchell, Wolfgang Koenig, Barbara McKnight, J. Wouter Jukema, Alan F. Wright, Maria Sabater-Lleal, Charles Kooperberg, Albert Hofman, Talin Haritunians, Martina Müller-Nurasyid, Jie Huang, Jie Yao, Marcus E. Kleber, Pau Navarro, Nicholas L. Smith, Jennifer E. Huffman, Lynda M. Rose, Russell P. Tracy, Antti-Pekka Sarin, Stefania Bandinelli, Ian J. Deary, Aarno Palotie, Saonli Basu, Caroline Hayward, Kent D. Taylor, Winfried März, Aaron R. Folsom, Anne Grotevendt, Lawrence F. Bielak, Tarunveer S. Ahluwalia, Ming-Huei Chen, Alexander Teumer, Graciela E. Delgado, Sharon L.R. Kardia, Peter K. Joshi, Wendy L. McArdle, Toshiko Tanaka, Jing Hua Zhao, Diane M. Becker, Pierre-Emmanuel Morange, Alanna C. Morrison, Annette Kifley, Igor Rudan, Lorna M. Lopez, Kay-Tee Khaw, Nicholas J. Wareham, Eco J. C. de Geus, Mohsen Ghanbari, Jari Lahti, Tatijana Zemunik, John M. Starr, Magdalena Zoledziewska, Anuj Goel, Dena G. Hernandez, Abbas Dehghan, Ozren Polasek, Melanie Waldenberger, Helene Riess, Rodney J. Scott, Qiong Yang, Robert A. Scott, Nancy S. Jenny, Johanna Mazur, Weihong Tang, Paul M. Ridker, Torben Hansen, Anders Hamsten, James F. Wilson, Jouke J. Hottenga, Cristina Venturini, Paul L. Auer, Geoffrey H. Tofler, Pirro G. Hysi, Mark G. Mcevoy, Ann Rumley, Fernando Rivadeneira, Naveed Sattar, Ivana Kolcic, Jie Jin Wang, Jingmin Liu, Stella Trompet, Elizabeth G. Holliday, Sarah H. Wild, Maristella Steri, Uwe Völker, Tanja Zeller, Patricia A. Peyser, P. Eline Slagboom, Massimo Mangino, André G. Uitterlinden, Paul S. de Vries, Dorret I. Boomsma, Harry Campbell, Vera Grossmann, Gonneke Willemsen, Katri Räikkönen, Edoardo Fiorillo, Ares Rocanin-Arjo, Gordon D.O. Lowe, David P. Strachan, Anton J. M. de Craen, Moniek P.M. de Maat, David-Alexandre Trégouët, Jennifer A. Brody, Rehan Qayyum, Lisa R. Yanek, Luigi Ferrucci, Andreas Greinacher, Lewis C. Becker, Hugh Watkins, David J. Stott, Min A. Jhun, Tina L. Berentzen, Annette Peters, Bengt Sennblad, Daniel I. Chasman, Lihong Qi, Christopher Oldmeadow, Harald Binder, Xiuqing Guo, John Attia, Bruce M. Psaty

المساهمون: Nutrition, obésité et risque thrombotique (NORT), Institut National de la Recherche Agronomique (INRA)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Biological Psychology, EMGO+ - Quality of Care, Amsterdam Neuroscience - Mood, Anxiety, Psychosis, Stress & Sleep, Aix Marseille Université (AMU)-Institut National de la Recherche Agronomique (INRA)-Institut National de la Santé et de la Recherche Médicale (INSERM), Epidemiology, Hematology, Internal Medicine

المصدر: Human Molecular Genetics, 25(2), 358-370
Human Molecular Genetics
Human Molecular Genetics, Oxford University Press (OUP), 2015, 25 (2), pp.358-370. ⟨10.1093/hmg/ddv454⟩
Human Molecular Genetics, 25(2), 358-370. Oxford University Press
de Vries, P S, Chasman, D I, Sabater-Lleal, M, Chen, M H, Huffman, J E, Steri, M, Tang, W, Teumer, A, Marioni, R E, Grossmann, V, Hottenga, J J, Willemsen, G, de Geus, E J C, Boomsma, D I, Cucca, F, Tracy, R, Watkins, H, Reiner, A P, Folsom, A R, Ridker, P M, O'Donnell, C J, Smith, N L, Strachan, D P & Dehghan, A 2016, ' A meta-analysis of 120,246 individuals identifies 18 new loci for fibrinogen concentration ', Human Molecular Genetics, vol. 25, no. 2, pp. 358-370 . https://doi.org/10.1093/hmg/ddv454Test

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Netherlands Twin Register (NTR), Single-nucleotide polymorphism, Genome-wide association study, Biology, Polymorphism, Single Nucleotide, White People, 03 medical and health sciences, INDEL Mutation, Genetics, Humans, 1000 Genomes Project, International HapMap Project, Indel, Molecular Biology, Genetics (clinical), ComputingMilieux_MISCELLANEOUS, Aged, Genetic association, Aged, 80 and over, Association Studies Articles, Fibrinogen, [SDV.MHEP.HEM]Life Sciences [q-bio]/Human health and pathology/Hematology, General Medicine, Middle Aged, Genetic architecture, 030104 developmental biology, Genetic Loci, Female, GENOME-WIDE ASSOCIATION, C-REACTIVE PROTEIN, CARDIOVASCULAR-DISEASE, CIRCULATING FIBRINOGEN, GENETIC ARCHITECTURE, VARIANTS, DESIGN, HEMOSTASIS, RESOURCE, HEALTH, Imputation (genetics), Genome-Wide Association Study

وصف الملف: text; application/vnd.openxmlformats-officedocument.wordprocessingml.document

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdd6ce9c52e253d0a5d0162a8a3295ccTest
http://hdl.handle.net/1887/112436Test

المؤلفون: Thomas J. Wang, Jennifer E. Ho, Eugene P. Rhee, Anahita Ghorbani, Ming-Huei Chen, Robert E. Gerszten, Martin G. Larson, Ramachandran S. Vasan, Susan Cheng, Clary B. Clish, Michelle J. Keyes

المصدر: PLoS ONE
PLoS ONE, Vol 11, Iss 2, p e0148361 (2016)

مصطلحات موضوعية: 0301 basic medicine, Blood Glucose, Male, Physiology, lcsh:Medicine, Blood Pressure, Biochemistry, Vascular Medicine, Body Mass Index, Framingham Heart Study, Endocrinology, Glucose Metabolism, Drug Metabolism, Metabolites, Medicine and Health Sciences, Prospective Studies, lcsh:Science, 2. Zero hunger, Multidisciplinary, Fasting, Phenotype, Physiological Parameters, Metabolome, Carbohydrate Metabolism, Female, Metabolic Networks and Pathways, Research Article, Adult, medicine.medical_specialty, Endocrine Disorders, Computational biology, Biology, 03 medical and health sciences, Insulin resistance, Metabolomics, Diabetes mellitus, Internal medicine, medicine, Diabetes Mellitus, Humans, Pharmacokinetics, Obesity, Dyslipidemias, Pharmacology, Endocrine Physiology, Myocardium, lcsh:R, Body Weight, Biology and Life Sciences, medicine.disease, 030104 developmental biology, Metabolism, Metabolic Disorders, lcsh:Q, Insulin Resistance, Body mass index

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20db639ad7387f0b0660662be8428619Test
https://pubmed.ncbi.nlm.nih.gov/26863521Test