المؤلفون: Myrna C.B. Godoy, Jean Pierre J. Issa, Hoa H.N. Pham, Humam Kadara, Alexandre Reuben, Paul Scheet, Ignacio I. Wistuba, Dan Su, Ara A. Vaporciyan, Chi Wan Chow, P. Andrew Futreal, Xin Hu, Runzhe Chen, Linghua Wang, Lisha Ying, J. Jack Lee, Jianhua Zhang, Boris Sepesi, Harvey I. Pass, John V. Heymach, Jian Carrot-Zhang, Carmen Behrens, Junya Fujimoto, Junya Fukuoka, Marcos R. Estecio, Jianjun Zhang, Brett W. Carter, Nicholas McGranahan, Yue Lu, Mara B. Antonoff

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications

مصطلحات موضوعية: Male, Epigenomics, 0301 basic medicine, Lung Neoplasms, Carcinogenesis, General Physics and Astronomy, medicine.disease_cause, Epigenome, 0302 clinical medicine, Mutation Rate, Chromosome instability, Tumor Microenvironment, Cancer genomics, Copy-number variation, Lung, Aged, 80 and over, Mutation, Multidisciplinary, Methylation, Middle Aged, 030220 oncology & carcinogenesis, Reduced representation bisulfite sequencing, DNA methylation, Disease Progression, Adenocarcinoma, Female, Adult, DNA Copy Number Variations, Tumour heterogeneity, Science, Adenocarcinoma of Lung, Biology, Article, General Biochemistry, Genetics and Molecular Biology, Genetic Heterogeneity, 03 medical and health sciences, Chromosomal Instability, medicine, Humans, Atypical adenomatous hyperplasia, Aged, Hyperplasia, General Chemistry, DNA Methylation, medicine.disease, Survival Analysis, 030104 developmental biology, Mutagenesis, Cancer research, Precancerous Conditions, Non-small-cell lung cancer

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c28d5ae9768cd6c19fb4d9d6edb29718Test
https://doaj.org/article/031719f1a9f8488a91a5917acd62743fTest

المؤلفون: Mohammad Azab, Scott D. Lunin, Patricia Kropf, Nikolai A. Podoltsev, Jesus G. Berdeja, Michael R. Savona, Todd L. Rosenblat, Harold N. Keer, Hagop M. Kantarjian, Katherine Walsh, Guillermo Garcia-Manero, Wendy Stock, Elias Jabbour, Raoul Tibes, Jean Pierre J. Issa, Karen Yee, Joseph R. Mace, Ellen K. Ritchie, Elizabeth A. Griffiths, Casey O'Connell, Gail J. Roboz, Yong Hao

المصدر: The Lancet Haematology. 6:e317-e327

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Neutropenia, Adolescent, Decitabine, Antineoplastic Agents, Severity of Illness Index, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, medicine, Clinical endpoint, Humans, Adverse effect, Survival rate, Aged, Aged, 80 and over, Dose-Response Relationship, Drug, business.industry, Myelodysplastic syndromes, Hematology, Middle Aged, medicine.disease, Thrombocytopenia, Survival Rate, Treatment Outcome, Tolerability, Hypomethylating agent, International Prognostic Scoring System, Myelodysplastic Syndromes, 030220 oncology & carcinogenesis, Azacitidine, Female, business, 030215 immunology, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::020d3a14be9a90c2cbe74c5f5714074dTest
https://doi.org/10.1016/s2352-3026Test(19)30029-8

المؤلفون: Charly R. Good, Andrew Kelly, Jozef Madzo, Jean Pierre J. Issa, Patricia Kropf, Priyanka Madireddi, Jaroslav Jelinek

المصدر: Leukemia

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Cancer Research, medicine.medical_specialty, NPM1, Biology, Article, Epigenesis, Genetic, 03 medical and health sciences, AML, medicine, Humans, DNA (Cytosine-5-)-Methyltransferases, DMP, Epigenetics, Aged, Aged, 80 and over, DNA methylation, CIMP, Cytogenetics, Nuclear Proteins, demethylation, Myeloid leukemia, Hematology, Middle Aged, Prognosis, Phenotype, Up-Regulation, 3. Good health, Leukemia, Myeloid, Acute, 030104 developmental biology, fms-Like Tyrosine Kinase 3, Oncology, CpG site, Mutation, Fms-Like Tyrosine Kinase 3, Cancer research, DNMT3A, CpG Islands, Female, Nucleophosmin, hypomethylation

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e406302f22dd4376a5c76741af9c5a4bTest
https://doi.org/10.1038/s41375-018-0084-2Test

المؤلفون: Karen W.L. Yee, Wendy Stock, Mohammad Azab, Katherine Walsh, Patricia Kropf, Michael R. Savona, Raoul Tibes, Todd L. Rosenblat, Elias Jabbour, Edwin P. Rock, Nikolai A. Podoltsev, Jesus G. Berdeja, Jean Pierre J. Issa, Farhad Ravandi, Hagop M. Kantarjian, Guillermo Garcia-Manero, David A. Rizzieri, Yong Hao, Casey O'Connell, Gail J. Roboz, Elizabeth A. Griffiths

المصدر: The Lancet Oncology. 18:1317-1326

مصطلحات موضوعية: Adult, 0301 basic medicine, medicine.medical_specialty, Maximum Tolerated Dose, Population, Phases of clinical research, Decitabine, Kaplan-Meier Estimate, Neutropenia, Risk Assessment, Disease-Free Survival, Drug Administration Schedule, Article, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, medicine, Humans, Neoplasm Invasiveness, Prospective Studies, Infusions, Intravenous, education, Prospective cohort study, Aged, Neoplasm Staging, Aged, 80 and over, education.field_of_study, Dose-Response Relationship, Drug, business.industry, Myelodysplastic syndromes, Remission Induction, Age Factors, Middle Aged, Prognosis, medicine.disease, Survival Analysis, Surgery, Leukemia, Myeloid, Acute, Regimen, Treatment Outcome, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, Azacitidine, Patient Safety, business, Febrile neutropenia, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::831965ab308b57b5ad258bda3c291389Test
https://doi.org/10.1016/s1470-2045Test(17)30576-4

المؤلفون: Yue Lu, Ricki J. Colman, Jozef Madzo, Jean Pierre J. Issa, Jaroslav Jelinek, Shoudan Liang, Shinji Maegawa, Justin T. Lee, Tomomitsu Tahara

المصدر: Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, Adult, Male, medicine.medical_specialty, Aging, Adolescent, Science, Longevity, General Physics and Astronomy, Biology, General Biochemistry, Genetics and Molecular Biology, Article, Epigenesis, Genetic, 03 medical and health sciences, Mice, Internal medicine, Age related, Gene expression, medicine, Animals, Humans, Epigenetics, Child, lcsh:Science, Epigenesis, Aged, Caloric Restriction, Genetics, Regulation of gene expression, Aged, 80 and over, Multidisciplinary, Infant, Newborn, Caloric theory, Infant, General Chemistry, Methylation, DNA Methylation, Middle Aged, Macaca mulatta, 030104 developmental biology, Endocrinology, Gene Expression Regulation, Child, Preschool, DNA methylation, Female, lcsh:Q

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10213650dd6d5a10433df4d58d584f00Test
https://doaj.org/article/7df8716f28e94df0a4d186d22d31c1a2Test

المؤلفون: Jean Pierre J. Issa, Hagop M. Kantarjian, Jaroslav Jelinek, Henry C. Fung, Mohammad Azab, Patricia Kropf, Woonbok Chung, Xiang Yao Su, Gail J. Roboz, Andrew Kelly

المصدر: Clinical Epigenetics

مصطلحات موضوعية: 0301 basic medicine, Oncology, Neuroblastoma RAS viral oncogene homolog, Male, medicine.disease_cause, 0302 clinical medicine, AML, CDKN2B, Genetics (clinical), Aged, 80 and over, Myeloid leukemia, Genomics, Guadecitabine, Middle Aged, 3. Good health, Leukemia, Leukemia, Myeloid, Acute, Treatment Outcome, 030220 oncology & carcinogenesis, DNA methylation, Azacitidine, Female, KRAS, Mutations, Adult, medicine.medical_specialty, DNA methyltransferase, 03 medical and health sciences, Young Adult, DNA methylation inhibitor, Internal medicine, Genetics, medicine, Biomarkers, Tumor, Humans, Molecular Biology, Survival rate, Aged, business.industry, Research, DNA Methylation, medicine.disease, Survival Analysis, 030104 developmental biology, Drug resistance, Mutation, Gene expression, Neoplasm Recurrence, Local, business, Developmental Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fba87adcbd903da019b3a83670791cfaTest
http://europepmc.org/articles/PMC6647096Test

المؤلفون: Elias J. Jabbour, Katherine Walsh, Pietro Taverna, Yong Hao, Wendy Stock, Jean Pierre J. Issa, Woonbok Chung, James N. Lowder, David A. Rizzieri, Elizabeth A. Griffiths, Casey O'Connell, Gail J. Roboz, Aram Oganesian, Karen Yee, Mohammad Azab, Sue Naim, Hagop M. Kantarjian, Raoul Tibes, Naval Daver

المصدر: The Lancet Oncology. 16:1099-1110

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Maximum Tolerated Dose, Azacitidine, Decitabine, Gastroenterology, Disease-Free Survival, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Aged, Neoplasm Staging, Dose-Response Relationship, Drug, business.industry, Myelodysplastic syndromes, Standard treatment, Middle Aged, Prognosis, medicine.disease, Effective dose (pharmacology), Leukemia, Myeloid, Acute, Regimen, Oncology, Tolerability, Myelodysplastic Syndromes, Immunology, Female, business, Febrile neutropenia, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bf7f6496beb4b783b51523e78219598Test
https://doi.org/10.1016/s1470-2045Test(15)00038-8

المؤلفون: S. Yu, C. E. Bueso-Ramos, Steve Kornblau, Jaroslav Jelinek, Andrew Kelly, Rong He, Yue Lu, Justin T. Lee, Matteo Cesaroni, Rodolphe Taby, Farhad Ravandi, Shoudan Liang, Sherry Pierce, Y. Li, Frank Neumann, Jean Pierre J. Issa, Bela Patel, Jumpei Yamazaki, Heike Kroeger, Hagop M. Kantarjian

المصدر: Leukemia

مصطلحات موضوعية: 0301 basic medicine, Adult, Male, Risk, Cancer Research, IDH1, Adolescent, Datasets as Topic, Pilot Projects, Biology, Gene mutation, Article, 03 medical and health sciences, Young Adult, 0302 clinical medicine, AML, CEBPA, Humans, Epigenetics, neoplasms, Aged, Retrospective Studies, DNA methylation, CpG Island Methylator Phenotype, CIMP, Myeloid leukemia, Hematology, DNA, Neoplasm, Middle Aged, Prognosis, Survival Analysis, digestive system diseases, Isocitrate Dehydrogenase, 3. Good health, Leukemia, Myeloid, Acute, 030104 developmental biology, Phenotype, Oncology, CpG site, 030220 oncology & carcinogenesis, Mutation, Cancer research, CpG Islands, Female, IDH2

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fcbf18e2f1a2c29a53538ffc554bd31Test
https://pubmed.ncbi.nlm.nih.gov/28074068Test

المؤلفون: Judith Garriga, Jaroslav Jelinek, Tomoyuki Shibata, Ichiro Hirata, Woonbok Chung, Tomomitsu Tahara, Marcos R. Estecio, Jean Pierre J. Issa, Tomiyasu Arisawa, Shinji Maegawa

المصدر: Cancer Prevention Research. 6:1093-1100

مصطلحات موضوعية: Adult, Male, Risk, Oncology, Cancer Research, medicine.medical_specialty, Biology, Article, CDH1, Young Adult, Stomach Neoplasms, Internal medicine, Biomarkers, Tumor, medicine, Humans, Aged, Whole blood, Case-control study, Cancer, Promoter, DNA, Sequence Analysis, DNA, Methylation, DNA Methylation, Middle Aged, Telomere, medicine.disease, Molecular biology, CpG site, Case-Control Studies, DNA methylation, biology.protein, CpG Islands, Female

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8859aecef176c92025fb91cfdea4a52fTest
https://doi.org/10.1158/1940-6207.capr-13-0034Test

المؤلفون: Vladimir Divoky, Karel Indrak, Lucie Lanikova, Martina Divoka, Jana Kucerova, Josef T. Prchal, Jean Pierre J. Issa, Thalia Papayannopoulou

المصدر: Human Mutation. 34:1361-1365

مصطلحات موضوعية: Adult, Transcription, Genetic, medicine.drug_class, RNA Stability, beta-Globins, Biology, Article, Transcription (biology), hemic and lymphatic diseases, Gene Order, Genetics, medicine, Humans, Gene Silencing, Allele, Promoter Regions, Genetic, Enhancer, Gene, Alleles, Genetics (clinical), Messenger RNA, beta-Thalassemia, Histone deacetylase inhibitor, DNA Methylation, Molecular biology, Introns, Chromatin, Alternative Splicing, Mutagenesis, Insertional, Long Interspersed Nucleotide Elements, Gene Expression Regulation, DNA methylation, CpG Islands, Female

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::807dec0f56a00e0a33e4d24685da6de3Test
https://doi.org/10.1002/humu.22383Test