التفاصيل البيبلوغرافية
| العنوان: |
Risk Factors for Human T-Cell Lymphotropic Virus Types I and II (HTLV-I and -II) in Blood Donors |
| المؤلفون: |
Schreiber, GB, Murphy†, EL, Horton*, JA, Wright*, DJ, Garfein*, R, Chien*, H Co, Nass‡, CC |
| المصدر: |
JAIDS Journal of Acquired Immune Deficiency Syndromes, vol 14, iss 3 |
| بيانات النشر: |
eScholarship, University of California |
| سنة النشر: |
1997 |
| المجموعة: |
University of California: eScholarship |
| مصطلحات موضوعية: |
Biomedical and Clinical Sciences, Clinical Sciences, Drug Abuse (NIDA only), Rare Diseases, Substance Misuse, Infectious Diseases, Aetiology, 2.2 Factors relating to the physical environment, Reproductive health and childbirth, Good Health and Well Being, Adult, Behavior, Blood Donors, Deltaretrovirus Infections, Demography, Female, Human T-lymphotropic virus 1, Human T-lymphotropic virus 2, Humans, Male, Middle Aged, Multivariate Analysis, Risk Factors, United States, HTLV-I, HTLV-II, epidemiology, transfusion, injection drug use, sexual transmission |
| جغرافية الموضوع: |
263 - 271 |
| الوصف: |
In the United States, blood donors have been routinely screened for human T-cell lymphotropic virus (HTLV) since 1988. HTLV-I and -II seropositive blood donors have been identified through confirmatory testing at five participating blood centers and frequency-matched seronegative controls provided information on potential HTLV sociodemographic, parenteral, and sexual risk factors during structured interviews. After adjustment, low educational attainment; accidental needlesticks or cuts; prior blood transfusion; > or = 7 sex partners; and a sex partner from an HTLV-I endemic area were significantly associated with both HTLV-I and -II. Gender did not modify the odds ratios (OR) in the final logistic regression models, despite apparent male-female differences in gender-specific bivariable analysis. Injection drug use (IDU) or having sex with an IDUs were significant risks for HTLV-II, but not for HTLV-I. The OR for donors who had IDU sex partners was 20.6 times higher than those who did not. For IDUs, the OR was increased 10.5 times over nonusers. Abortion was a significant HTLV-II risk factor for women. Our findings indicate that IDU and sex with IDUs are important risk factors for HTLV-II transmission, even among low-risk populations such as blood donors. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
unknown |
| العلاقة: |
qt55k6s9f4; https://escholarship.org/uc/item/55k6s9f4Test |
| الإتاحة: |
https://escholarship.org/uc/item/55k6s9f4Test |
| حقوق: |
public |
| رقم الانضمام: |
edsbas.19F1EA49 |
| قاعدة البيانات: |
BASE |
