المؤلفون: Victoria Atkinson, Céleste Lebbé, Jessica C. Hassel, Catalin Mihalcioiu, Cornelia Mauch, Ewa Kalinka-Warzocha, Ian M. Waxman, Ana Arance, Piotr Rutkowski, Kerry J. Savage, Vanna Chiarion-Sileni, Caroline Dutriaux, Micaela Hernberg, Abstr Act, Laurent Mortier, Catriona M. McNeil, Brian Sharkey, Caroline Robert, Dirk Schadendorf, Michele Maio, Christine Horak, Georgina V. Long, Lotta Lundgren-Eriksson, Benjamin Brady, Helen Gogas, Francesco Cognetti, Henrik Schmidt, Paolo A. Ascierto, Julie Charles

المصدر: Robert, C, Long, G V, Brady, B, Dutriaux, C, Maio, M, Mortier, L, Hassel, J C, Rutkowski, P, McNeil, C, Kalinka-Warzocha, E, Savage, K J, Hernberg, M M, Lebbé, C, Charles, J, Mihalcioiu, C, Chiarion-Sileni, V, Mauch, C, Cognetti, F, Arance, A, Schmidt, H, Schadendorf, D, Gogas, H, Lundgren-Eriksson, L, Horak, C, Sharkey, B, Waxman, I M, Atkinson, V & Ascierto, P A 2015, ' Nivolumab in previously untreated melanoma without BRAF mutation ', The New England Journal of Medicine, vol. 372, no. 4, pp. 320-30 . https://doi.org/10.1056/NEJMoa1412082Test
New England Journal of Medicine; 372(4), pp 320-330 (2015)

مصطلحات موضوعية: Adult, Male, Proto-Oncogene Proteins B-raf, medicine.medical_specialty, Adolescent, Dacarbazine, Programmed Cell Death 1 Receptor, Medizin, Phases of clinical research, Ipilimumab, Antineoplastic Agents, Pembrolizumab, ipilimumab-refractory metastatic melanoma, Gastroenterology, Disease-Free Survival, Young Adult, Double-Blind Method, Nivolumab, melanoma, ipilimumab-refractory metastatic melanoma, Internal medicine, Medicine, Humans, Survival rate, Melanoma, Aged, Aged, 80 and over, business.industry, Hazard ratio, Antibodies, Monoclonal, General Medicine, Middle Aged, medicine.disease, Surgery, Survival Rate, Nivolumab, Cancer and Oncology, Female, business, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07253c758028e0b62a420832a391b6ecTest
https://pubmed.ncbi.nlm.nih.gov/25511188Test

المؤلفون: Stéphan Vagner, Alexander M.M. Eggermont, Lise Boussemart, Yungan Tao, Laurence Vilcot, Pierre Blanchard, Caroline Robert, Brigitte Dréno, Barouyr Baroudjian, Frédéric Dhermain, Christine Mateus, Eric Deutsch, Emilie Routier

المصدر: European journal of dermatology : EJD. 24(2)

مصطلحات موضوعية: Adult, Male, Proto-Oncogene Proteins B-raf, Radiosensitizer, Pathology, medicine.medical_specialty, Radiation-Sensitizing Agents, Indoles, Skin Neoplasms, medicine.medical_treatment, Dermatology, Remission induction, medicine, Combined Modality Therapy, Humans, Vemurafenib, Melanoma, Aged, 80 and over, Sulfonamides, business.industry, Remission Induction, Antitumor response, medicine.disease, Clinical trial, Radiation therapy, Cancer research, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59d40e250153d141af1fea8d646604c0Test
https://pubmed.ncbi.nlm.nih.gov/24721778Test

المؤلفون: Daniil Stroyakovskiy, Jochen Utikal, Keith T. Flaherty, Daniele Ouellet, Virginia Ferraresi, Michelle Casey, Claus Garbe, Axel Hauschild, V. Chiarion Sileni, Caroline Robert, Helen Gogas, Antoni Ribas, Michael Millward, Nadezhda Kovalenko, Jean-Jacques Grob, Jhangir G. Irani, Paul Nathan, Dirk Schadendorf, John B. A. G. Haanen, V. Probachai, Mario Mandalà, F. de Braud, Johan Hansson, Georgina V. Long, Igor Bondarenko, Kiran Patel, Ngocdiep T. Le, Anne-Marie Martin, James Larkin, Ana Arance, T. Jouary, Peter Mohr, Douglas J. DeMarini, Céleste Lebbé, Evgeny Levchenko

مصطلحات موضوعية: Adult, Male, Proto-Oncogene Proteins B-raf, medicine.medical_specialty, Fever, Pyridones, Medizin, Kaplan-Meier Estimate, Pyrimidinones, Gastroenterology, Disease-Free Survival, chemistry.chemical_compound, Double-Blind Method, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, Oximes, Carcinoma, medicine, Clinical endpoint, Humans, Melanoma, Aged, Mitogen-Activated Protein Kinase Kinases, Cobimetinib, Trametinib, business.industry, Hazard ratio, Imidazoles, Binimetinib, Dabrafenib, General Medicine, Middle Aged, medicine.disease, Surgery, chemistry, Mutation, Female, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::266d13e0581ba3c486d28c2d159ca1daTest
http://hdl.handle.net/11391/1480877Test

المؤلفون: Kerstin Trunzer, Antoni Ribas, C. Lebbé, Dirk Schadendorf, Paul B. Chapman, Jeffrey A. Sosman, Axel Hauschild, Alessandro Testori, Omid Hamid, Paolo A. Ascierto, Grant A. McArthur, Michele Maio, John M. Kirkwood, Thomas Jouary, Brigitte Dréno, Alexander M.M. Eggermont, John B. A. G. Haanen, James Larkin, Claus Garbe, Reinhard Dummer, Ivor Caro, Ming Yin, Paul Lorigan, Stephen J O'Day, Suzanne Cheng, David Hogg, Keith T. Flaherty, Caroline Robert

المساهمون: University of Zurich, McArthur, Grant A

المصدر: The Lancet. Oncology, vol 15, iss 3

مصطلحات موضوعية: Male, Indoles, Medizin, Gastroenterology, chemistry.chemical_compound, Vemurafenib, Melanoma, Cancer, Sulfonamides, education.field_of_study, Hazard ratio, 10177 Dermatology Clinic, Binimetinib, Middle Aged, Dacarbazine, Oncology, 2730 Oncology, Female, medicine.drug, Adult, Proto-Oncogene Proteins B-raf, medicine.medical_specialty, Clinical Trials and Supportive Activities, Oncology and Carcinogenesis, Population, 610 Medicine & health, Disease-Free Survival, Clinical Research, Internal medicine, Genetics, medicine, Humans, Oncology & Carcinogenesis, education, Protein Kinase Inhibitors, Aged, Cobimetinib, Performance status, business.industry, Prevention, medicine.disease, Surgery, Good Health and Well Being, chemistry, Mutation, business, Follow-Up Studies

وصف الملف: 573_McArthur_GA_et_al._-_Lancet_Oncol_2014.pdf - application/pdf; application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::377d825d8360489bb92f735b7e5e1cb4Test
http://hdl.handle.net/11365/1081256Test

المؤلفون: Eric Deutsch, Christine Mateus, Gorana Tomasic, Catherine Boivin, Caroline Robert, Yun Gan Tao, Emilie Routier, Joël Claveau, Lise Boussemart

المصدر: JAMA dermatology. 149(7)

مصطلحات موضوعية: Adult, Male, Proto-Oncogene Proteins B-raf, Radiosensitizer, medicine.medical_specialty, Indoles, Skin Neoplasms, medicine.medical_treatment, Folliculitis, Dermatology, Radiation Tolerance, medicine, Radiodermatitis, Humans, Vemurafenib, Adverse effect, Melanoma, Protein Kinase Inhibitors, Sulfonamides, business.industry, Middle Aged, medicine.disease, Radiation therapy, Radiation Recall Dermatitis, Female, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae431471b2e37a6b631505cdcfaceea6Test
https://pubmed.ncbi.nlm.nih.gov/23699661Test

المؤلفون: Marta Nyakas, Stuart Spencer, Mireille Cantarini, Reinhard Dummer, Gabriella Liszkay, Paul Lorigan, Ana Arance, Caroline Robert, Mark R. Middleton, Dirk Schadendorf, Ralf Gutzmer, Kevin B. Kim

المساهمون: University of Zurich, Robert, Caroline

مصطلحات موضوعية: Male, Skin Neoplasms, Time Factors, medicine.medical_treatment, DNA Mutational Analysis, Medizin, Phases of clinical research, Kaplan-Meier Estimate, Gastroenterology, Antineoplastic Combined Chemotherapy Protocols, Melanoma, 10177 Dermatology Clinic, Middle Aged, Dacarbazine, Europe, Phenotype, Treatment Outcome, Oncology, Tolerability, Female, 2730 Oncology, Brazil, medicine.drug, Adult, Proto-Oncogene Proteins B-raf, medicine.medical_specialty, 610 Medicine & health, Neutropenia, Placebo, Disease-Free Survival, Drug Administration Schedule, Double-Blind Method, Internal medicine, medicine, Humans, Genetic Predisposition to Disease, Antineoplastic Agents, Alkylating, Protein Kinase Inhibitors, Aged, Proportional Hazards Models, Chemotherapy, Intention-to-treat analysis, business.industry, medicine.disease, United States, Surgery, Logistic Models, Mutation, Selumetinib, Neoplasms, Unknown Primary, Benzimidazoles, business

وصف الملف: 555_Robert_C_et_al._-_Lancet_Oncol_2013.pdf - application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c63162f2b90b77be9846693c33b4197Test
https://www.ncbi.nlm.nih.gov/pubmed/23735514Test

المؤلفون: Julie Switzky, Dirk Schadendorf, Tabea Wilhelm, Mary E. Guckert, Richard F. Kefford, Vicki L. Goodman, Laurent Mortier, Paul B. Chapman, Michael R. W. Streit, Lisa Zimmer, Suzanne Swann, Georgina V. Long, Alain Algazi, Uwe Trefzer, Anne-Marie Martin, Caroline Robert, Michael A. Davies, Igor Puzanov, John M. Kirkwood, Hussein Tawbi, Axel Hauschild, Paolo A. Ascierto

المصدر: The Lancet. Oncology. 13(11)

مصطلحات موضوعية: Adult, Male, Proto-Oncogene Proteins B-raf, medicine.medical_specialty, Medizin, Neutropenia, Disease-Free Survival, Internal medicine, Oximes, medicine, Clinical endpoint, Humans, Adverse effect, Melanoma, Neoplasm Staging, business.industry, Brain Neoplasms, Imidazoles, Dabrafenib, Middle Aged, medicine.disease, Surgery, Oncology, Response Evaluation Criteria in Solid Tumors, Cohort, Mutation, Female, business, medicine.drug, Brain metastasis

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::336c875fae193c757be84091ff5a92e0Test
https://pubmed.ncbi.nlm.nih.gov/23116995Test

المؤلفون: Keith T, Flaherty, Caroline, Robert, Peter, Hersey, Paul, Nathan, Claus, Garbe, Mohammed, Milhem, Lev V, Demidov, Jessica C, Hassel, Piotr, Rutkowski, Peter, Mohr, Reinhard, Dummer, Uwe, Trefzer, James M G, Larkin, Jochen, Utikal, Brigitte, Dreno, Marta, Nyakas, Mark R, Middleton, Jürgen C, Becker, Michelle, Casey, Laurie J, Sherman, Frank S, Wu, Daniele, Ouellet, Anne-Marie, Martin, Kiran, Patel, Dirk, Schadendorf, Mary, Richardson

المصدر: The New England journal of medicine. 367(2)

مصطلحات موضوعية: Oncology, Adult, Male, Proto-Oncogene Proteins B-raf, medicine.medical_specialty, Pyridones, Dacarbazine, MAP Kinase Kinase 2, Medizin, MAP Kinase Kinase 1, Antineoplastic Agents, Kaplan-Meier Estimate, Pyrimidinones, Disease-Free Survival, chemistry.chemical_compound, Young Adult, Internal medicine, medicine, Humans, Vemurafenib, Melanoma, Protein Kinase Inhibitors, Aged, Trametinib, Cobimetinib, Aged, 80 and over, business.industry, MEK inhibitor, Hazard ratio, Dabrafenib, General Medicine, Middle Aged, medicine.disease, Surgery, Intention to Treat Analysis, chemistry, Mutation, Female, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::778f247f586f7abe700c37ec7f75715aTest
http://ora.ox.ac.uk/objects/uuid:17a4cd0c-72ea-46f7-ab36-457c375b3557Test

المؤلفون: Levi A. Garraway, Antje Sucker, Emanuele Palescandolo, Piotr Dziunycz, Damien Kee, Nyam Kamsu-Kom, Patrick A. Oberholzer, Günther F.L. Hofbauer, Grant A. McArthur, Clinton J. Chalk, Caroline Robert, Adriano Piris, Robert T. Jones, Kristin G. Ardlie, Dirk Schadendorf, Christine Roden, Laura E. MacConaill

المساهمون: University of Zurich, Garraway, L A

المصدر: Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 30(3)

مصطلحات موضوعية: Sorafenib, Adult, Male, Niacinamide, Proto-Oncogene Proteins B-raf, Cancer Research, Indoles, Skin Neoplasms, Genotype, Pyridines, Medizin, 610 Medicine & health, medicine.disease_cause, Mass Spectrometry, CDKN2A, Original Reports, Carcinoma, medicine, Humans, 1306 Cancer Research, HRAS, Vemurafenib, Protein Kinase Inhibitors, Aged, Aged, 80 and over, Mitogen-Activated Protein Kinase Kinases, Mutation, Sulfonamides, business.industry, Phenylurea Compounds, Benzenesulfonates, 10177 Dermatology Clinic, Middle Aged, medicine.disease, Gene Expression Regulation, Neoplastic, Oncology, Cancer research, Carcinoma, Squamous Cell, 2730 Oncology, Female, KRAS, business, medicine.drug

وصف الملف: RAS_Mutations_Are_Associated_With_the_Development_of_Cutaneous_Squamous_Cell_Tumors_in_Patients_Treated_With_RAF_Inhibitors_JCO_2011.pdf - application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3567cff10b5be5b331260c345ce8a46Test
https://pubmed.ncbi.nlm.nih.gov/22067405Test

المؤلفون: Sabine Druillennec, Alain Spatz, Vladimir Lazar, Philippe Dessen, Joost van den Oord, Caroline Robert, Brigitte Bressac-de Paillerets, Caroline Kannengiesser, Stefan Michiels, Alain Sarasin, Fabienne Lesueur, V. Winnepenninckx, Alain Eychène

المصدر: Molecular oncology. 1(4)

مصطلحات موضوعية: Neuroblastoma RAS viral oncogene homolog, Adult, Male, Proto-Oncogene Proteins B-raf, Cancer Research, Skin Neoplasms, Adolescent, Ultraviolet Rays, DNA Mutational Analysis, Mutation, Missense, Biology, medicine.disease_cause, Young Adult, Cell Movement, Gene expression, Genetics, medicine, Humans, Child, neoplasms, Melanoma, Aged, Regulation of gene expression, Aged, 80 and over, Mutation, Melanosomes, Gene Expression Profiling, Immunity, Infant, General Medicine, Middle Aged, medicine.disease, Microphthalmia-associated transcription factor, Molecular biology, digestive system diseases, Gene expression profiling, Gene Expression Regulation, Neoplastic, Genes, ras, Oncology, Child, Preschool, Cutaneous melanoma, Papers, Cancer research, Molecular Medicine, Female, DNA Probes

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aa656a369a59863ffb03c4699bc7235Test
https://pubmed.ncbi.nlm.nih.gov/19383316Test