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1

دورية أكاديمية

Development of MK-8353, an orally administered ERK1/2 inhibitor, in patients with advanced solid tumors

المصدر: JCI Insight. 3(4)

مصطلحات موضوعية: Pharmacology and Pharmaceutical Sciences, Biomedical and Clinical Sciences, Clinical Sciences, Oncology and Carcinogenesis, Clinical Research, Cancer, Clinical Trials and Supportive Activities, 6.1 Pharmaceuticals, Evaluation of treatments and therapeutic interventions, Administration, Oral, Adult, Animals, Biological Availability, Cell Line, Tumor, Diarrhea, Dogs, Dose-Response Relationship, Drug, Drug Eruptions, Drug Evaluation, Preclinical, Fatigue, Female, Humans, Indazoles, MAP Kinase Signaling System, Male, Maximum Tolerated Dose, Mice, Middle Aged, Mitogen-Activated Protein Kinase 1, Mitogen-Activated Protein Kinase 3, Nausea, Neoplasm Staging, Neoplasms, Protein Kinase Inhibitors, Pyridines, Pyrrolidines, Rats, Triazoles, Xenograft Model Antitumor Assays, Young Adult, Clinical Trials, Melanoma, Oncology, Signal transduction, Biomedical and clinical sciences, Health sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/9552v98dTest

View record in eScholarship

2

دورية أكاديمية

Frequent discordance in PD-1 and PD-L1 expression between primary breast tumors and their matched distant metastases

المؤلفون: Manson, Quirine F., Schrijver, Willemijne A.M.E., ter Hoeve, Natalie D., Moelans, Cathy B., van Diest, Paul J.

المساهمون: Pathologie Groep Van Diest, Pathologie patiënten zorg, Heelkunde Opleiding, Cancer, Pathologie

وصف الملف: image/pdf

العلاقة: https://dspace.library.uu.nl/handle/1874/392039Test

الإتاحة: https://dspace.library.uu.nl/handle/1874/392039Test

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3

miR-3156-5p is downregulated in serum of MEN1 patients and regulates expression of MORF4L2

المؤلفون: Kreepa G Kooblall, Victoria J Stokes, Omair A Shariq, Katherine A English, Mark Stevenson, John Broxholme, Benjamin Wright, Helen E Lockstone, David Buck, Simona Grozinsky-Glasberg, Christopher J Yates, Rajesh V Thakker, Kate E Lines

المصدر: Endocrine-Related Cancer. 29:557-568

مصطلحات موضوعية: Adult, Aged, 80 and over, Cancer Research, Adolescent, Endocrinology, Diabetes and Metabolism, Middle Aged, MicroRNAs, Young Adult, Endocrinology, Oncology, Child, Preschool, Mutation, Multiple Endocrine Neoplasia Type 1, Quality of Life, Humans, Child, Aged, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da6064ac844ac3ef5945d7eafc8f9477Test
https://doi.org/10.1530/erc-22-0045Test

4

PD‐L1 expression is associated with the spontaneous regression of patients with methotrexate‐associated lymphoproliferative disorders

المؤلفون: Tadashi Yoshino, Naoya Nakamura, Misa Sakamoto, Tomoka Ikeda, Yuria Egusa, Yoshito Nishimura, Yasuharu Sato, Azusa Fujita, Misato Doi, Noriko Iwaki, Asami Nishikori, Midori Filiz Nishimura, Yuka Gion

المصدر: Cancer Medicine, Vol 11, Iss 2, Pp 417-432 (2022)
Cancer Medicine

مصطلحات موضوعية: Male, rheumatoid arthritis, Cancer Research, medicine.medical_treatment, Remission, Spontaneous, Spontaneous remission, Kaplan-Meier Estimate, Gastroenterology, B7-H1 Antigen, Arthritis, Rheumatoid, Pathogenesis, programmed cell death‐ligand 1, rheumatoid arthritis, immune system diseases, hemic and lymphatic diseases, heterocyclic compounds, skin and connective tissue diseases, Research Articles, classic Hodgkin lymphoma, RC254-282, Aged, 80 and over, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Middle Aged, Hodgkin Disease, Oncology, Antirheumatic Agents, Female, Lymphoma, Large B-Cell, Diffuse, Research Article, medicine.drug, Adult, musculoskeletal diseases, medicine.medical_specialty, methotrexate‐associated lymphoproliferative disorder, diffuse large B-cell lymphoma, Lymphoproliferative disorders, programmed cell death-ligand 1, Internal medicine, medicine, Humans, methotrexate-associated lymphoproliferative disorder, Radiology, Nuclear Medicine and imaging, Aged, Chemotherapy, business.industry, diffuse large B‐cell lymphoma, Clinical Cancer Research, medicine.disease, Lymphoma, Discontinuation, Methotrexate, business, Diffuse large B-cell lymphoma

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0febac51292e55b26e6f5b3df183fcd5Test
https://doaj.org/article/6e2da9f68eeb4074af0bba01de8c7953Test

5

Dual PD-1 and CTLA-4 Checkpoint Blockade Using Balstilimab and Zalifrelimab Combination as Second-Line Treatment for Advanced Cervical Cancer: An Open-Label Phase II Study

المؤلفون: David M. O'Malley, Maryna Neffa, Bradley J. Monk, Tamar Melkadze, Marilyn Huang, Anna Kryzhanivska, Iurie Bulat, Tarek M. Meniawy, Andrea Bagameri, Edward W. Wang, Bernard Doger de Speville Uribe, Roberto Hegg, Waldo Ortuzar Feliu, Marek Ancukiewicz, Iwona Lugowska

المصدر: Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 40(7)

مصطلحات موضوعية: Adult, Cancer Research, Programmed Cell Death 1 Receptor, Uterine Cervical Neoplasms, Middle Aged, Antibodies, Monoclonal, Humanized, Prognosis, Survival Rate, Young Adult, Oncology, Antineoplastic Combined Chemotherapy Protocols, Humans, CTLA-4 Antigen, Female, Neoplasm Recurrence, Local, Immune Checkpoint Inhibitors, Aged, Follow-Up Studies

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c78f165fe897f0fc91d786a7a3628a54Test
https://pubmed.ncbi.nlm.nih.gov/35486885Test

6

Tumor immunity is related to 18F‐FDG uptake in thymic epithelial tumor

المؤلفون: Kyoichi Kaira, Ou Yamaguchi, Hiroyuki Nitanda, Hirozo Sakaguchi, Akitoshi Yanagihara, Hiroshi Kagamu, Tomonori Kawasaki, Tetsuya Umesaki, Kunihiko Kobayashi, Atsuto Mouri, Hisao Imai, Kosuke Hashimoto, Ryo Taguchi, Ichiei Kuji, Masanori Yasuda

المصدر: Cancer Medicine, Vol 10, Iss 18, Pp 6317-6326 (2021)
Cancer Medicine

مصطلحات موضوعية: Male, Cancer Research, Pathology, Biopsy, B7-H1 Antigen, Warburg Effect, Oncologic, Neoplasms, Glandular and Epithelial, Thymic carcinoma, Research Articles, RC254-282, Aged, 80 and over, Glucose Transporter Type 1, medicine.diagnostic_test, biology, HIF‐1α, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Middle Aged, Thymectomy, Oncology, Positron emission tomography, thymic epithelial tumor, immunohistochemistry, Immunohistochemistry, Female, medicine.symptom, Research Article, Adult, medicine.medical_specialty, Thymoma, Thymus Gland, Fluorodeoxyglucose F18, PD-L1, medicine, Humans, Radiology, Nuclear Medicine and imaging, Aged, Retrospective Studies, Performance status, business.industry, Clinical Cancer Research, Thymus Neoplasms, Hypoxia (medical), medicine.disease, Hypoxia-Inducible Factor 1, alpha Subunit, Programmed Cell Death 1 Ligand 2 Protein, PD‐L1, Positron-Emission Tomography, PD‐L2, biology.protein, Tumor Hypoxia, GLUT1, 18F‐FDG uptake, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15261651d62bd866f1c6478c8c6c3373Test
https://doaj.org/article/a8142366e6a1438799401c111ae0c803Test

7

Pembrolizumab Plus Ipilimumab Following Anti-PD-1/L1 Failure in Melanoma

المصدر: J Clin Oncol

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f53f50387d5994f75ceeba750e8bc2f9Test
https://doi.org/10.1200/jco.21.00079Test

8

Investigation of the relationship between immune checkpoints and mismatch repair deficiency in recurrent and nonrecurrent glioblastoma

المؤلفون: Mustafa Emre Ercin, Ismail Saygin, Emel Çakir

المصدر: Turkish Journal of Medical Sciences

مصطلحات موضوعية: Oncology, Adult, Male, medicine.medical_specialty, Programmed cell death, Adolescent, medicine.medical_treatment, Programmed Cell Death 1 Receptor, DNA Mismatch Repair, Article, B7-H1 Antigen, Young Adult, Immune system, Neoplastic Syndromes, Hereditary, Internal medicine, PMS2, programmed cell death protein ligand 1 (PD-L1), Medicine, Humans, Child, Immune Checkpoint Inhibitors, Aged, Aged, 80 and over, business.industry, Brain Neoplasms, Microsatellite instability, General Medicine, Immunotherapy, Middle Aged, medicine.disease, Immune checkpoint, mismatch repair, programmed cell death protein 1 (PD-1), Child, Preschool, Immunohistochemistry, DNA mismatch repair, Female, Microsatellite Instability, Neoplasm Recurrence, Local, business, Glioblastoma, Colorectal Neoplasms

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a44b4cb671bcd3f1641f45f158cabf5bTest
http://europepmc.org/articles/PMC8569775Test

9

Massive digital gene expression analysis reveals different predictive profiles for immune checkpoint inhibitor therapy between adenocarcinoma and squamous cell carcinoma of advanced lung cancer

المؤلفون: Tomoko Yoshida, Kazuhiko Takeda, Toshihiko Kaneda, Hiroaki Yanagimoto, Takao Yoshida, Kayoko Kibata, Koji Tsuta, Takayasu Kurata, Hiroshige Yoshioka

المصدر: BMC Cancer, Vol 22, Iss 1, Pp 1-10 (2022)

مصطلحات موضوعية: Adult, Male, Cancer Research, Lung Neoplasms, Immune checkpoint inhibitors, Programmed Cell Death 1 Receptor, Gene Expression, Adenocarcinoma, GPI-Linked Proteins, Antigens, CD, Antigens, Neoplasm, Predictive Value of Tests, Carcinoma, Non-Small-Cell Lung, Proto-Oncogene Proteins, Gene expression, medicine, Biomarkers, Tumor, Genetics, Humans, Basal cell, RNA, Messenger, Anti PD-1 antibody, Lung cancer, Immune Checkpoint Inhibitors, HLA-DP beta-Chains, RC254-282, Adaptor Proteins, Signal Transducing, Aged, Retrospective Studies, Aged, 80 and over, business.industry, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Middle Aged, medicine.disease, Cadherins, Neoplasm Proteins, Treatment Outcome, Nivolumab, Oncology, Drug Resistance, Neoplasm, Cancer research, Carcinoma, Squamous Cell, Female, Advanced non-small cell lung cancer, business, Apoptosis Regulatory Proteins, Transcriptome

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c799aa8ffcd78d88cbc59de6ae181520Test
https://doaj.org/article/42a2cfeec3fa448fb601a19458098818Test

10

دورية أكاديمية

Human Islet Response to Selected Type 1 Diabetes-Associated Bacteria: A Transcriptome-Based Study

المؤلفون: Abdellatif, Ahmed M., Jensen Smith, Heather, Harms, Robert Z., Sarvetnick, Nora

المصدر: Journal Articles: Eppley Institute

مصطلحات موضوعية: Adult, Bacteroides, Clostridiales, Cytokines, Diabetes Mellitus, Type 1, Gastrointestinal Microbiome, Gene Expression Regulation, Bacterial, Humans, Islets of Langerhans, Middle Aged, RNA-Seq, Transcriptome, Young Adult, Neoplasms, Oncology

وصف الملف: application/pdf

View record in BASE

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