نتائج البحث

1

Mechanistic insights into immune checkpoint inhibitor-related hypophysitis: a form of paraneoplastic syndrome

المؤلفون: Ryusaku Matsumoto, Masaaki Yamamoto, Genzo Iguchi, Shin Urai, Hidenori Fukuoka, Wataru Ogawa, Kentaro Suda, Hiroki Shichi, Keitaro Kanie, Yutaka Takahashi, Hironori Bando, Yasunori Fujita

المصدر: Cancer Immunology, Immunotherapy

مصطلحات موضوعية: Male, Cancer Research, Pro-Opiomelanocortin, Paraneoplastic Syndromes, Programmed Cell Death 1 Receptor, Autoimmunity, Hypopituitarism, Immune checkpoint inhibitor, medicine.disease_cause, B7-H1 Antigen, Mice, 0302 clinical medicine, Neoplasms, Immunology and Allergy, CTLA-4 Antigen, Corticotrophs, Immune Checkpoint Inhibitors, Aged, 80 and over, biology, Middle Aged, Oncology, 030220 oncology & carcinogenesis, Paraneoplastic syndrome, Female, Original Article, Immunotherapy, Antibody, hormones, hormone substitutes, and hormone antagonists, Adult, endocrine system, Hypophysitis, Immunology, 030209 endocrinology & metabolism, Adrenocorticotropic hormone, 03 medical and health sciences, Antigen, medicine, Animals, Humans, Aged, Retrospective Studies, business.industry, medicine.disease, biology.protein, Ectopic expression, Corticotropic cell, business, Adrenal Insufficiency

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3acc181a81511e7fe6b828ea748faa32Test
https://hdl.handle.net/20.500.14094/90008773Test

2

SAMHD1 expression is associated with low immune activation but not correlated with HIV‑1 DNA levels in CD4+ T cells of patients with HIV‑1

المؤلفون: Jie Li, Longteng Jin, Shanshan Huang, Chuanhua Gao, Changzhong Jin

المصدر: Molecular Medicine Reports

مصطلحات موضوعية: Adult, CD4-Positive T-Lymphocytes, Male, 0301 basic medicine, Cancer Research, HIV Infections, HIV-1 DNA, Biology, Biochemistry, Peripheral blood mononuclear cell, Gene Expression Regulation, Enzymologic, elite controllers, immune activation, SAM Domain and HD Domain-Containing Protein 1, 03 medical and health sciences, 0302 clinical medicine, Genetics, Humans, sterile α motif and histidine/aspartic acid domain-containing protein 1, Molecular Biology, Gene, Regulation of gene expression, Oncogene, Interferon-alpha, Articles, Middle Aged, Viral Load, Cell cycle, Reverse transcriptase, 030104 developmental biology, Anti-Retroviral Agents, Oncology, Apoptosis, 030220 oncology & carcinogenesis, DNA, Viral, Immunology, HIV-1, Leukocytes, Mononuclear, RNA, Viral, Molecular Medicine, Female, SAMHD1

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::779b8ae7dcad85cf36332ff19bee6b43Test
https://doi.org/10.3892/mmr.2020.11153Test

3

Association of cancer progression with elevated expression of programmed cell death protein 1 ligand 1 by upper tract urothelial carcinoma and increased tumor-infiltrating lymphocyte density

المؤلفون: Kyoko Arai, Takao Kamai, Akinori Nukui, Minoru Kobayashi, Hideo Yuki, Takahiro Narimatsu, Yoshitatsu Fukabori, Toshiki Kijima, Ken-Ichiro Yoshida, Hideyuki Abe, Tsunehito Kambara, Hironori Betsunoh, Masahiro Yashi

المصدر: Cancer Immunology, Immunotherapy

مصطلحات موضوعية: Male, Cancer Research, Lymphocyte, Kidney, Nephroureterectomy, B7-H1 Antigen, Immune tolerance, 0302 clinical medicine, Tumor Microenvironment, Neutrophil-to-lymphocyte ratio (NLR), Immunology and Allergy, Stage (cooking), Aged, 80 and over, 0303 health sciences, Univariate analysis, Middle Aged, Prognosis, Kidney Neoplasms, Progression-Free Survival, Programmed cell death 1 ligand 1 (PD-L1), medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, Upper tract urothelial carcinoma (UTUC), Disease Progression, Immunohistochemistry, Female, Original Article, Tumor-infiltrating lymphocyte (TIL), Adult, Immunology, 03 medical and health sciences, Lymphocytes, Tumor-Infiltrating, medicine, Humans, Aged, Retrospective Studies, 030304 developmental biology, Carcinoma, Transitional Cell, Tumor microenvironment, Ureteral Neoplasms, Tumor-infiltrating lymphocytes, business.industry, Cancer, medicine.disease, Cancer research, Neoplasm Grading, Ureter, business, Follow-Up Studies

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a089064114954a8996f5b69f009caefTest
https://doi.org/10.1007/s00262-020-02499-7Test

4

Exhaustion in tumor-infiltrating Mucosal-Associated Invariant T (MAIT) cells from colon cancer patients

المؤلفون: William Rodin, Filip Ahlmanner, Elinor Bexe Lindskog, Yvonne Wettergren, Louis Szeponik, Kamil Kajetan Zajt, Marianne Quiding Järbrink, Patrik Sundström

المصدر: Cancer Immunology, Immunotherapy

مصطلحات موضوعية: Adult, Male, Cancer Research, Exhaustion, Immunology, Programmed Cell Death 1 Receptor, Tim-3, Lymphocyte Activation, Mucosal-Associated Invariant T Cells, Flow cytometry, 03 medical and health sciences, 0302 clinical medicine, Immunity, Antigens, CD, Blocking antibody, PD-1, medicine, Tumor Microenvironment, Immunology and Allergy, Cytotoxic T cell, Humans, Secretion, Hepatitis A Virus Cellular Receptor 2, MAIT cell, 030304 developmental biology, Aged, Cell Proliferation, Aged, 80 and over, 0303 health sciences, Tumor microenvironment, CD39, medicine.diagnostic_test, Effector, Chemistry, Apyrase, Middle Aged, Colorectal cancer, In vitro, Phenotype, Oncology, Colonic Neoplasms, Cancer research, Cytokines, Original Article, Female, Biomarkers, 030215 immunology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8846e11fd7e69e73f9cd68dd02080acTest
http://europepmc.org/articles/PMC8571139Test

5

Human leukocyte antigen I is significantly downregulated in patients with myxoid liposarcomas

المؤلفون: Masanori Hayashi, Tetsuro Yamagishi, Chihaya Imai, Hajime Umezu, Takashi Ariizumi, Yudai Murayama, Akira Ogose, Naoki Oike, Hiroyuki Kawashima, Hiroshi Hatano, Naoto Endo

المصدر: Cancer Immunology, Immunotherapy

مصطلحات موضوعية: Male, Cancer Research, Pathology, medicine.medical_treatment, Liposarcomas, B7-H1 Antigen, 0302 clinical medicine, HLA Antigens, Tumor Microenvironment, Immunology and Allergy, Programmed death ligand 1, Aged, 80 and over, 0303 health sciences, Middle Aged, Prognosis, Immunohistochemistry, Liposarcoma, Myxoid, Progression-Free Survival, Oncology, 030220 oncology & carcinogenesis, Original Article, Female, Human leukocyte antigen I, Adult, medicine.medical_specialty, Adolescent, Tumor immune microenvironment, Immunology, Down-Regulation, Human leukocyte antigen, Liposarcoma, Pleomorphic Liposarcoma, 03 medical and health sciences, Young Adult, Lymphocytes, Tumor-Infiltrating, medicine, Humans, neoplasms, 030304 developmental biology, Aged, Myxoid liposarcoma, Tumor-infiltrating lymphocytes, business.industry, Macrophages, Histocompatibility Antigens Class I, Immunotherapy, medicine.disease, body regions, CD163+ macrophages, business, CD163

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80679c1ba2c44a0ce4ca344ffcd402aeTest
http://europepmc.org/articles/PMC8571150Test

6

First-line treatment of advanced/metastatic melanoma with anti-PD-1 antibodies: multicenter experience in Poland

المصدر: Immunotherapy. 13:297-307

مصطلحات موضوعية: Adult, Male, Oncology, medicine.medical_specialty, Multivariate analysis, Drug-Related Side Effects and Adverse Reactions, medicine.medical_treatment, Programmed Cell Death 1 Receptor, Immunology, Pembrolizumab, Antibodies, Monoclonal, Humanized, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Humans, Immunology and Allergy, Medicine, 030212 general & internal medicine, Stage (cooking), Adverse effect, Immune Checkpoint Inhibitors, Melanoma, Aged, Retrospective Studies, Aged, 80 and over, business.industry, Immunotherapy, Middle Aged, Prognosis, medicine.disease, Progression-Free Survival, Survival Rate, Clinical trial, Nivolumab, Treatment Outcome, 030220 oncology & carcinogenesis, Female, Poland, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75481f1f9c5cc0cca549a49f8bad084dTest
https://doi.org/10.2217/imt-2020-0217Test

7

Development and validation of a PD-L1/PD-1/CD8 axis-based classifier to predict cancer survival of upper tract urothelial carcinoma after radical nephroureterectomy

المؤلفون: Weibin Hou, Jian Huang, Kun Xia, Meihua Yang, Meng Yang, Junyu Chen, Bo Wang, Tianxin Lin, Wenlong Zhong, Bingkun Zhou, Xiaofei Wang, Hao Yu

المصدر: Cancer Immunology, Immunotherapy. 70:2657-2668

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bec96ee69828b45ab4f3871ce3fc8c4bTest
https://doi.org/10.1007/s00262-020-02827-xTest

8

Impacts of pembrolizumab therapy on immune phenotype in patients with high-grade neuroendocrine neoplasms

المؤلفون: Kerry S. Campbell, R. Katherine Alpaugh, Alexander W. MacFarlane, Ho Man Yeung, Paul F. Engstrom, Essel Dulaimi, Arvind Dasari, Namrata Vijayvergia

المصدر: Cancer Immunol Immunother

مصطلحات موضوعية: Adult, Male, Oncology, Cancer Research, medicine.medical_specialty, Programmed Cell Death 1 Receptor, Immunology, Pembrolizumab, Antibodies, Monoclonal, Humanized, Article, Flow cytometry, Antineoplastic Agents, Immunological, Lymphocytes, Tumor-Infiltrating, TIGIT, Internal medicine, Biomarkers, Tumor, medicine, Humans, Immunology and Allergy, Prospective Studies, Receptors, Immunologic, Aged, biology, medicine.diagnostic_test, Tumor-infiltrating lymphocytes, business.industry, CD69, Middle Aged, Prognosis, medicine.disease, Peripheral, Gene Expression Regulation, Neoplastic, Survival Rate, Neuroendocrine Tumors, biology.protein, Female, Antibody, business, Progressive disease, Follow-Up Studies

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::427872e9fa04075bcec253b57f12b396Test
https://doi.org/10.1007/s00262-020-02811-5Test

9

Genetic profile of adult T‐cell leukemia/lymphoma in Okinawa: Association with prognosis, ethnicity, and HTLV‐1 strains

المؤلفون: Kazuho Morichika, Shugo Sakihama, Hiroaki Masuzaki, Sawako Nakachi, Jun-Nosuke Uchihara, Kennosuke Karube, Shingo Nakayama, Kazuko Sakai, Satoko Morishima, Kazuto Nishio, Masaki Hayashi, Rumiko Saito, Takeaki Tomoyose, Takuya Fukushima, Megumi Miyara, Takashi Miyagi, Kazuiku Ohshiro

المصدر: Cancer Science

مصطلحات موضوعية: 0301 basic medicine, Genetics, Genomics and Proteomics, Male, Cancer Research, RHOA, Genotyping Techniques, Kaplan-Meier Estimate, Gene mutation, medicine.disease_cause, Genetic analysis, 0302 clinical medicine, Japan, immune system diseases, hemic and lymphatic diseases, Ethnicity, Leukemia-Lymphoma, Adult T-Cell, geographical mutation heterogeneity, Aged, 80 and over, Mutation, Human T-lymphotropic virus 1, biology, High-Throughput Nucleotide Sequencing, General Medicine, Gene Products, tax, Genetic Profile, Middle Aged, Prognosis, Leukemia, Oncology, 030220 oncology & carcinogenesis, Original Article, Female, Adult, integrated clinico‐genetic analysis, DNA Copy Number Variations, Polymorphism, Single Nucleotide, Adult T-cell leukemia/lymphoma, 03 medical and health sciences, PRDM1, medicine, Biomarkers, Tumor, adult T‐cell leukemia/lymphoma, Humans, Aged, human T‐cell leukemia virus type I, Original Articles, medicine.disease, tax subgroup, HTLV-I Infections, Lymphoma, 030104 developmental biology, Immunology, biology.protein, Follow-Up Studies

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d517e8449311ef95a6ecc2bd5d2502d6Test
http://europepmc.org/articles/PMC7935801Test

10

High tumor mutational burden and T-cell activation are associated with long-term response to anti-PD1 therapy in Lynch syndrome recurrent glioblastoma patient

المؤلفون: Elena Anghileri, Junfei Zhao, Valeria Cuccarini, Gaetano Finocchiaro, Monica Patanè, Natalia Di Ianni, Marica Eoli, Tiziana Langella, Antonio Iavarone, Serena Pellegatta, Raul Rabadan, Bianca Pollo, Rosina Paterra

المصدر: Cancer Immunology, Immunotherapy. 70:831-842

مصطلحات موضوعية: Adult, Cancer Research, Biopsy, T-Lymphocytes, T cell, Programmed Cell Death 1 Receptor, Immunology, Neuroimaging, Germline, 03 medical and health sciences, 0302 clinical medicine, Immunophenotyping, Immune system, Exome Sequencing, Biomarkers, Tumor, Humans, Immunology and Allergy, Medicine, Molecular Targeted Therapy, Immune Checkpoint Inhibitors, Temozolomide, business.industry, medicine.disease, Colorectal Neoplasms, Hereditary Nonpolyposis, Combined Modality Therapy, Immunohistochemistry, Magnetic Resonance Imaging, Lynch syndrome, Treatment Outcome, medicine.anatomical_structure, Oncology, MSH2, Mutation, Retreatment, Cancer research, Female, Neoplasm Recurrence, Local, Nivolumab, Glioblastoma, business, 030215 immunology, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91e9d6d866c397beb05c63097c4dbcb1Test
https://doi.org/10.1007/s00262-020-02769-4Test

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