نتائج البحث

1

Expression of immunoreactive inducible nitric oxide synthase in pancreatic islet cells from newly diagnosed and long-term type 1 diabetic donors is heterogeneous and not disease-associated

المؤلفون: Knut Dahl-Jørgensen, Shiva Reddy, Lars Krogvold, Owen Martin, Charlton Martin, Kevin Xueying Sun, Aamenah Al-Ani

المصدر: Cell and Tissue Research. 384:655-674

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, endocrine system, medicine.medical_specialty, Histology, Adolescent, endocrine system diseases, Nitric Oxide Synthase Type II, Nitric Oxide, Glucagon, Pathology and Forensic Medicine, Proinflammatory cytokine, Nitric oxide, Islets of Langerhans, Young Adult, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Internal medicine, medicine, Humans, Beta (finance), Cells, Cultured, Type 1 diabetes, geography, geography.geographical_feature_category, biology, Chemistry, Cell Biology, medicine.disease, Islet, Nitric oxide synthase, Diabetes Mellitus, Type 1, 030104 developmental biology, Endocrinology, biology.protein, Female, Beta cell, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6728a9832de8ac370bf9e4176fa86c25Test
https://doi.org/10.1007/s00441-020-03340-4Test

2

The Regulatory Effect of MicroRNA-101-3p on Disc Degeneration by the STC1/VEGF/MAPK Pathway

المؤلفون: Yueming Song, Xin He, Xi Yang, Kun Shi, Yong Huang, Juehan Wang, Limin Liu, Ce Zhu, Ganjun Feng, Jingcheng Wang, Leizhen Huang

المصدر: Oxidative Medicine and Cellular Longevity, Vol 2021 (2021)
Oxidative Medicine and Cellular Longevity

وصف الملف: text/xhtml

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b819441873b03d859c1f092c406c12d5Test
https://doi.org/10.1155/2021/1073458Test

3

Methionine Commits Cells to Differentiate Into Plasmablasts Through Epigenetic Regulation ofBTBandCNCHomolog 2 by the MethyltransferaseEZH2

المؤلفون: Shingo Nakayamada, Masanobu Ueno, Tong Zhang, Mingzeng Zhang, Maiko Hajime, Naoaki Ohkubo, Shigeru Iwata, Hiroko Miyata, Jie Fan, Kaoru Yamagata, Yasuyuki Todoroki, He Hao, Yoshiya Tanaka

المصدر: Arthritis & Rheumatology. 72:1143-1153

مصطلحات موضوعية: Adult, Male, X-Box Binding Protein 1, 0301 basic medicine, Methyltransferase, Plasma Cells, Immunology, B-cell receptor, mTORC1, Mechanistic Target of Rapamycin Complex 1, CD19, Epigenesis, Genetic, 03 medical and health sciences, chemistry.chemical_compound, Methionine, 0302 clinical medicine, Rheumatology, Interferon, medicine, Humans, Lupus Erythematosus, Systemic, Syk Kinase, Immunology and Allergy, Enhancer of Zeste Homolog 2 Protein, Amino Acids, Cells, Cultured, B cell, Autoantibodies, chemistry.chemical_classification, biology, Precursor Cells, B-Lymphoid, Cell Differentiation, Middle Aged, Amino acid, Cell biology, Basic-Leucine Zipper Transcription Factors, 030104 developmental biology, medicine.anatomical_structure, Gene Expression Regulation, chemistry, Case-Control Studies, biology.protein, Female, Positive Regulatory Domain I-Binding Factor 1, 030215 immunology, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47f83c76a30bddc46586697dcc78ae03Test
https://doi.org/10.1002/art.41208Test

4

Salidroside can target both P4HB-mediated inflammation and melanogenesis of the skin

المؤلفون: Jing Jin, Cheng Yao, Cai-Bin Zhu, Hongqi Wang, Yuyan Yang, Huijuan Liu, Tao Sun, Jingxia Han, Zhi-Yuan Zhang, Yan Wang, Xintong Dai, Xiujuan Ding, Kai Yang

المصدر: Theranostics

مصطلحات موضوعية: Male, Tyrosinase, Skin Lightening Preparations, Skin Cream, Medicine (miscellaneous), Skin Pigmentation, Proximity ligation assay, Melanin, Mice, chemistry.chemical_compound, prolyl 4-hydroxylase beta polypeptide (P4HB), Glucosides, Hyperpigmentation, Pharmacology, Toxicology and Pharmaceutics (miscellaneous), Skin, integumentary system, medicine.diagnostic_test, Monophenol Monooxygenase, Chemistry, interferon regulatory factor 1 (IRF1), Salidroside, P4HB, Healthy Volunteers, Cell biology, Molecular Docking Simulation, Melanocytes, Female, medicine.symptom, Research Paper, Adult, Transcriptional Activation, Ultraviolet Rays, Procollagen-Proline Dioxygenase, Protein Disulfide-Isomerases, Inflammation, tyrosinase, upstream stimulatory factor 1 (USF1), Young Adult, Phenols, Western blot, Cell Line, Tumor, parasitic diseases, medicine, Animals, Humans, Melanins, Ubiquitination, Skin Aging, Disease Models, Animal, IRF1, Upstream Stimulatory Factors, Interferon Regulatory Factor-1

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aad408fac1a91ab323152981fbb84ac6Test
https://doi.org/10.7150/thno.47413Test

5

ABCA1- and ABCG1-mediated cholesterol efflux capacity of cerebrospinal fluid is impaired in Alzheimer's disease

المؤلفون: Franco Bernini, Maria Pia Adorni, Francesca Zimetti, Daniela Galimberti, Paolo Caffarra, Cinzia Marchi, Marco Spallazzi, Nicoletta Ronda, Federica Barocco

المصدر: Journal of Lipid Research, Vol 60, Iss 8, Pp 1449-1456 (2019)
J Lipid Res

مصطلحات موضوعية: 0301 basic medicine, Apolipoprotein E, Adult, Male, medicine.medical_specialty, apolipoprotein A-I, QD415-436, 030204 cardiovascular system & hematology, Biochemistry, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Endocrinology, Cerebrospinal fluid, Alzheimer Disease, Internal medicine, medicine, Dementia, Humans, ATP Binding Cassette Transporter, Subfamily G, Member 1, Aged, apolipoprotein E, ATP-binding cassette A1, Amyloid beta-Peptides, biology, Cholesterol, business.industry, Neurodegeneration, ATP-binding cassette G1, Cell Biology, Middle Aged, apolipoprotein E4, medicine.disease, Pathophysiology, Peptide Fragments, 030104 developmental biology, chemistry, ABCA1, biology.protein, cardiovascular system, Female, lipids (amino acids, peptides, and proteins), Efflux, business, Patient-Oriented and Epidemiological Research, apolipoproteins, ATP Binding Cassette Transporter 1

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c32af647e6d95ae13ea957fc028bbe95Test
http://www.sciencedirect.com/science/article/pii/S0022227520322392Test

6

Activation of angiotensin type 2 receptor attenuates testosterone-induced hypertension and uterine vascular resistance in pregnant rats

المؤلفون: Sathish Kumar, Jay S. Mishra

المصدر: Biol Reprod

مصطلحات موضوعية: Adult, 0301 basic medicine, Gestational hypertension, medicine.medical_specialty, Nitric Oxide Synthase Type III, Endothelium, Bradykinin, Vasodilation, 030204 cardiovascular system & hematology, Biology, Receptor, Angiotensin, Type 2, Receptor, Angiotensin, Type 1, Preeclampsia, Rats, Sprague-Dawley, Young Adult, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Enos, Internal medicine, medicine, Animals, Humans, Testosterone, Uterus, Cell Biology, General Medicine, medicine.disease, biology.organism_classification, Angiotensin II, Rats, 030104 developmental biology, Endocrinology, medicine.anatomical_structure, Reproductive Medicine, chemistry, Hypertension, Vascular resistance, Female, Vascular Resistance, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8311c4622599810c922ef90122b202d3Test
https://doi.org/10.1093/biolre/ioab051Test

7

Intracellular immune sensing promotes inflammation via gasdermin D–driven release of a lectin alarmin

المصدر: Nat Immunol

مصطلحات موضوعية: Lipopolysaccharides, Male, 0301 basic medicine, Galectin 1, Lipopolysaccharide, Mice, chemistry.chemical_compound, 0302 clinical medicine, Alarmins, Immunology and Allergy, Caspase, Aged, 80 and over, Mice, Knockout, biology, Intracellular Signaling Peptides and Proteins, Pyroptosis, Middle Aged, Up-Regulation, Cell biology, Necroptosis, Female, Inflammation Mediators, medicine.symptom, Signal transduction, Intracellular, Signal Transduction, Adult, animal structures, Immunology, Inflammation, PTPRC, Article, 03 medical and health sciences, Sepsis, otorhinolaryngologic diseases, medicine, Animals, Humans, Aged, Macrophages, Phosphate-Binding Proteins, Endotoxemia, Mice, Inbred C57BL, Disease Models, Animal, stomatognathic diseases, RAW 264.7 Cells, 030104 developmental biology, chemistry, Case-Control Studies, biology.protein, Leukocyte Common Antigens, HeLa Cells, 030215 immunology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcd368de112bdf46f79b07a7aa7e0a0dTest
https://doi.org/10.1038/s41590-020-00844-7Test

8

snRNA-seq reveals a subpopulation of adipocytes that regulates thermogenesis

المؤلفون: Aviv Regev, Eugene Drokhlyansky, Jozef Ukropec, Christian Wolfrum, Lucia Balazova, Gottfried Rudofsky, Wenfei Sun, Antonio Giordano, Lianggong Ding, Miroslav Balaz, Anna Sofie Husted, Patrik Stefanicka, Georgia Colleluori, Michal Slyper, Saverio Cinti, Zuzana Kovanicova, Thue W. Schwartz, Hua Dong

المصدر: Cell Metab

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04d0e829fb1d588b5e9be24e980e95e0Test
https://doi.org/10.1038/s41586-020-2856-xTest

9

Association of high HIF-1α levels in serous periodontitis with external root resorption by the NFATc1 pathway

المؤلفون: Chang-Jie Xiao, Xijiao Yu, Yanmei Du, Huan Jiang, Guangliang Bai

المصدر: Journal of Molecular Histology. 51:649-658

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Pathology, medicine.medical_specialty, Histology, Lipopolysaccharide, Physiology, Gene Expression, Osteoclasts, Severity of Illness Index, Severe periodontitis, Bone resorption, Mice, 03 medical and health sciences, chemistry.chemical_compound, medicine, Animals, Humans, Hypoxia, Periodontitis, Porphyromonas gingivalis, Aged, NFATC Transcription Factors, 030102 biochemistry & molecular biology, biology, business.industry, Cell Differentiation, Cell Biology, General Medicine, Middle Aged, Hypoxia (medical), Hypoxia-Inducible Factor 1, alpha Subunit, medicine.disease, biology.organism_classification, Resorption, Disease Models, Animal, 030104 developmental biology, medicine.anatomical_structure, chemistry, Female, Disease Susceptibility, Bone marrow, medicine.symptom, business, Biomarkers, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24824204692ccc6569f2ab0654ca45aeTest
https://doi.org/10.1007/s10735-020-09911-7Test

10

Palmitic acid induces inflammation in placental trophoblasts and impairs their migration toward smooth muscle cells through plasminogen activator inhibitor-1

المؤلفون: Stephen J. Lye, Caroline Dunk, Amanda M Rampersaud, Stephen J. Renaud

المصدر: Paediatrics Publications
Mol Hum Reprod

مصطلحات موضوعية: 0301 basic medicine, Embryology, Vascular smooth muscle, Placenta, Palmitic Acid, Palmitic acid, chemistry.chemical_compound, 0302 clinical medicine, Cell Movement, Pregnancy, Cells, Cultured, 0303 health sciences, Decidua, Obstetrics and Gynecology, Cell migration, Trophoblasts, Extravillous trophoblasts, medicine.anatomical_structure, Smooth muscle cells, Plasminogen activator inhibitor-1, 030220 oncology & carcinogenesis, Saturated fatty acid, Female, Inflammation Mediators, medicine.symptom, Adult, Myocytes, Smooth Muscle, Inflammation, Biology, Andrology, Young Adult, 03 medical and health sciences, Plasminogen Activator Inhibitor 1, Genetics, medicine, Humans, Interleukin 8, Obesity, Molecular Biology, 030304 developmental biology, Trophoblast, Original Articles, Cell Biology, Placentation, Pregnancy Complications, HEK293 Cells, 030104 developmental biology, Reproductive Medicine, chemistry, Developmental Biology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::add428a3d955bd0f1b31968efa47cc7bTest
https://doi.org/10.1093/molehr/gaaa061Test

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