نتائج البحث

1

Clonally expanded EOMES+ Tr1-like cells in primary and metastatic tumors are associated with disease progression

المؤلفون: Salvatore Siena, Emilia Maria Cristina Mazza, Giulia Della Chiara, Chiara Godano, Nicola Zucchini, Valeria Ranzani, Stefania Oliveto, Paola Gruarin, Jens Geginat, Roberto Bosotti, Claudia D'Oria, Elena Carelli, Pierluigi Novellis, Saveria Mazzara, Ylenia Silvestri, Marco Passaro, Alessio Amatu, Marco Alloisio, Antonio Lanzavecchia, Stefano Biffo, Giorgia Alvisi, Federica Gervasoni, Maria Lucia Sarnicola, N. Mariani, Alberto Bardelli, Ramona Bason, Jolanda Brummelman, Mariangela Lorenzo, Giulia Veronesi, Emanuela Bonoldi, Massimiliano Pagani, Daniele Prati, Enrico Opocher, Lorenzo Drufuca, Martina Martinovic, Andrea Sartore-Bianchi, Sergio Abrignani, Alessandro Giani, Marco De Simone, Enrico Lugli, Chiara Cordiglieri, Serena Curti, Grazisa Rossetti, Valeria Bevilacqua, Andrea Pisani Ceretti, Raoul J. P. Bonnal

المساهمون: Bonnal, R. J. P., Rossetti, G., Lugli, E., De Simone, M., Gruarin, P., Brummelman, J., Drufuca, L., Passaro, M., Bason, R., Gervasoni, F., Della Chiara, G., D'Oria, C., Martinovic, M., Curti, S., Ranzani, V., Cordiglieri, C., Alvisi, G., Mazza, E. M. C., Oliveto, S., Silvestri, Y., Carelli, E., Mazzara, S., Bosotti, R., Sarnicola, M. L., Godano, C., Bevilacqua, V., Lorenzo, M., Siena, S., Bonoldi, E., Sartore-Bianchi, A., Amatu, A., Veronesi, G., Novellis, P., Alloisio, M., Giani, A., Zucchini, N., Opocher, E., Ceretti, A. P., Mariani, N., Biffo, S., Prati, D., Bardelli, A., Geginat, J., Lanzavecchia, A., Abrignani, S., Pagani, M.

المصدر: Nature Immunology, 22, 735-745
Nature Immunology, 22, 6, pp. 735-745

مصطلحات موضوعية: Male, 0301 basic medicine, Lung Neoplasms, T-Lymphocytes, Cancer development and immune defence Radboud Institute for Molecular Life Sciences [Radboudumc 2], medicine.medical_treatment, Programmed Cell Death 1 Receptor, Drug Resistance, Datasets as Topic, Kaplan-Meier Estimate, Granzymes, 0302 clinical medicine, Cancer immunotherapy, Single-cell analysis, 80 and over, Immunology and Allergy, RNA-Seq, Non-Small-Cell Lung, Immune Checkpoint Inhibitors, Adjuvant, Colectomy, Chitinases, Cell Differentiation, Forkhead Transcription Factors, Middle Aged, Flow Cytometry, Regulatory, Adult, Aged, Aged, 80 and over, Carcinoma, Non-Small-Cell Lung, Cell Proliferation, Chemotherapy, Adjuvant, Clonal Hematopoiesis, Colon, Colorectal Neoplasms, Disease Progression, Drug Resistance, Neoplasm, Female, Gene Expression Regulation, Neoplastic, Humans, Primary Cell Culture, Single-Cell Analysis, T-Box Domain Proteins, T-Lymphocytes, Regulatory, Immunology, Biology, 03 medical and health sciences, Immune system, medicine, Chemotherapy, Neoplastic, Carcinoma, Immunotherapy, 030104 developmental biology, Gene Expression Regulation, Cell culture, Cancer research, Neoplasm, Granzyme K, Eomesodermin Homolog, Checkpoint Blockade Immunotherapy, 030215 immunology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73e12ccb9271b3892eb83d8342962f9dTest
https://doi.org/10.1038/s41590-021-00930-4Test

2

Human Wharton’s Jelly-Derived Mesenchymal Stromal Cells Primed by Tumor Necrosis Factor-α and Interferon-γ Modulate the Innate and Adaptive Immune Cells of Type 1 Diabetic Patients

المؤلفون: Mairvat Al- Mrahleh, Suzan Matar, Hanan Jafar, Suha Wehaibi, Nazneen Aslam, Abdalla Awidi

المصدر: Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2021)

مصطلحات موضوعية: Adult, Male, Adolescent, Regulatory T cell, type 1 diabetes, T-Lymphocytes, Immunology, Cell Communication, Biology, Adaptive Immunity, Lymphocyte Activation, regulatory T cells, Wharton’s jelly-derived mesenchymal stromal cells, Immunomodulation, Interferon-gamma, Young Adult, Immune system, Downregulation and upregulation, Immunity, Pregnancy, Wharton's jelly, medicine, Immunology and Allergy, Humans, Wharton Jelly, priming, Cells, Cultured, Original Research, Cell Proliferation, Tumor Necrosis Factor-alpha, Mesenchymal stem cell, tolerogenic dendritic cells, FOXP3, Cell Differentiation, Mesenchymal Stem Cells, Dendritic Cells, RC581-607, Coculture Techniques, Immunity, Innate, Interleukin 10, medicine.anatomical_structure, Diabetes Mellitus, Type 1, Gene Expression Regulation, Cancer research, Female, Immunologic diseases. Allergy

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::768c359149fa0ca19e8985b45f08795dTest
http://europepmc.org/articles/PMC8506215Test

3

High tumor mutational burden and T-cell activation are associated with long-term response to anti-PD1 therapy in Lynch syndrome recurrent glioblastoma patient

المؤلفون: Elena Anghileri, Junfei Zhao, Valeria Cuccarini, Gaetano Finocchiaro, Monica Patanè, Natalia Di Ianni, Marica Eoli, Tiziana Langella, Antonio Iavarone, Serena Pellegatta, Raul Rabadan, Bianca Pollo, Rosina Paterra

المصدر: Cancer Immunology, Immunotherapy. 70:831-842

مصطلحات موضوعية: Adult, Cancer Research, Biopsy, T-Lymphocytes, T cell, Programmed Cell Death 1 Receptor, Immunology, Neuroimaging, Germline, 03 medical and health sciences, 0302 clinical medicine, Immunophenotyping, Immune system, Exome Sequencing, Biomarkers, Tumor, Humans, Immunology and Allergy, Medicine, Molecular Targeted Therapy, Immune Checkpoint Inhibitors, Temozolomide, business.industry, medicine.disease, Colorectal Neoplasms, Hereditary Nonpolyposis, Combined Modality Therapy, Immunohistochemistry, Magnetic Resonance Imaging, Lynch syndrome, Treatment Outcome, medicine.anatomical_structure, Oncology, MSH2, Mutation, Retreatment, Cancer research, Female, Neoplasm Recurrence, Local, Nivolumab, Glioblastoma, business, 030215 immunology, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91e9d6d866c397beb05c63097c4dbcb1Test
https://doi.org/10.1007/s00262-020-02769-4Test

4

Characterization of the tumor immune microenvironment in human papillomavirus-positive and -negative head and neck squamous cell carcinomas

المؤلفون: Tracee L. McMiller, Lisa M. Rooper, Elizabeth D. Thompson, John B. A. G. Haanen, Alan E. Berger, Pia Kvistborg, Charlotte L. Zuur, Farah Succaria, Elizabeth L. Engle, Julie E. Stein, Suzanne L. Topalian, Michiel W. M. van den Brekel, Janis M. Taube

المساهمون: Maxillofacial Surgery (AMC), Oral and Maxillofacial Surgery

المصدر: Cancer Immunology, Immunotherapy, 70(5), 1227-1237. Springer Science and Business Media Deutschland GmbH
Succaria, F, Kvistborg, P, Stein, J E, Engle, E L, McMiller, T L, Rooper, L M, Thompson, E, Berger, A E, van den Brekel, M, Zuur, C L, Haanen, J, Topalian, S L & Taube, J M 2021, ' Characterization of the tumor immune microenvironment in human papillomavirus-positive and-negative head and neck squamous cell carcinomas ', Cancer Immunology, Immunotherapy, vol. 70, no. 5, pp. 1227-1237 . https://doi.org/10.1007/s00262-020-02747-wTest
Cancer immunology, immunotherapy, 70(5), 1227-1237. Springer Science and Business Media Deutschland GmbH
Cancer Immunol Immunother

مصطلحات موضوعية: Male, Cancer Research, T-Lymphocytes, Programmed Cell Death 1 Receptor, Alphapapillomavirus, B7-H1 Antigen, IDO, Cohort Studies, 0302 clinical medicine, PD-1, Tumor Microenvironment, Immunology and Allergy, Medicine, CD20, biology, Head and neck squamous cell carcinoma (HNSCC), FOXP3, Forkhead Transcription Factors, Middle Aged, Gene Expression Regulation, Neoplastic, Oncology, Head and Neck Neoplasms, Immunohistochemistry, Female, Adult, PD-L1, Human Papillomavirus Positive, HPV, CD3, Immunology, Article, 03 medical and health sciences, Immune system, SDG 3 - Good Health and Well-being, Biomarkers, Tumor, Humans, GITR, Aged, Neoplasm Staging, Squamous Cell Carcinoma of Head and Neck, business.industry, Papillomavirus Infections, Cancer research, biology.protein, Transcriptome, business, CD8, 030215 immunology