نتائج البحث

1

Genetic predisposition in the 2′-5′A pathway in the development of type 1 diabetes: potential contribution to dysregulation of innate antiviral immunity

المؤلفون: Martin Haupt-Jorgensen, Karsten Buschard, Flemming Pociot, Kristina Pedersen, Knut Dahl-Jørgensen, Ivan C. Gerling, Simranjeet Kaur, Lars Krogvold

المصدر: Diabetologia
Pedersen, K, Haupt-Jorgensen, M, Krogvold, L, Kaur, S, Gerling, I C, Pociot, F, Dahl-Jørgensen, K & Buschard, K 2021, ' Genetic predisposition in the 2′-5′A pathway in the development of type 1 diabetes : potential contribution to dysregulation of innate antiviral immunity ', Diabetologia, vol. 64, no. 8, pp. 1805-1815 . https://doi.org/10.1007/s00125-021-05469-5Test

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Ribonuclease L, Endocrinology, Diabetes and Metabolism, 030209 endocrinology & metabolism, Single-nucleotide polymorphism, Disease, Type 2 diabetes, Biology, Interferon α, RNase L, Type 1 interferon, Antiviral Agents, Polymorphism, Single Nucleotide, Article, Virus, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Immune system, Internal Medicine, Genetic predisposition, medicine, Humans, Genetic Predisposition to Disease, RNA, Messenger, Gene, Type 1 diabetes, Oligoribonucleotides, Adenine Nucleotides, RNA-Binding Proteins, medicine.disease, Immunity, Innate, Toll-like receptor 7, Diabetes Mellitus, Type 1, 030104 developmental biology, Gene Expression Regulation, Virus Diseases, Immunology, 2′-5′A pathway, 2′-5′ Oligoadenylate synthetase, Female, Genome-Wide Association Study

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc7c11e2de9bab5e6655271157f4e1c3Test
https://doi.org/10.1007/s00125-021-05469-5Test

2

Lipase elevation and type 1 diabetes mellitus related to immune checkpoint inhibitor therapy – A multicentre study of 90 patients from the German Dermatooncology Group

المؤلفون: Michael Momma, Carmen Loquai, Cristel Ruini, Corinna Kochanek, Kai-Martin Thoms, Selma Ugurel, Carola Berking, Lisa Zimmer, Friedegund Meier, Katharina C. Kähler, Lucie Heinzerling, Dirk Debus, Jessica C. Hassel, Imke Grimmelmann, Claudia Pföhler, Jochen Utikal, Rudolf A. Herbst, Thomas Eigentler, Ralf Gutzmer

المصدر: European Journal of Cancer. 149:1-10

مصطلحات موضوعية: Adult, Blood Glucose, Male, 0301 basic medicine, Cancer Research, medicine.medical_specialty, Skin Neoplasms, Time Factors, Medizin, Gastroenterology, Thyroiditis, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Predictive Value of Tests, Germany, Internal medicine, Diabetes mellitus, medicine, Humans, Lipase, Adverse effect, Immune Checkpoint Inhibitors, Melanoma, Aged, Retrospective Studies, Aged, 80 and over, Type 1 diabetes, biology, business.industry, Diabetes, Immune checkpoint inhibitors, Immune-related adverse events, Ipilimumab, Nivolumab, Pancreatitis, PD-1 inhibitor, Pembrolizumab, Biomarkers, Diabetes Mellitus, Type 1, Exocrine Pancreatic Insufficiency, Female, Middle Aged, Treatment Outcome, Up-Regulation, medicine.disease, Ketoacidosis, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, biology.protein, Skin cancer, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f46f4bea919fbf1345c4e5a2fd89e7ccTest
https://doi.org/10.1016/j.ejca.2021.02.017Test

3

Peripheral immune circadian variation, synchronisation and possible dysrhythmia in established type 1 diabetes

المؤلفون: Carmella Evans-Molina, Clive Wasserfall, Megan T Legge, Eleni Beli, Craig A. Beam, Ryan Silk, Kieran M. Mcgrail, Linda A. DiMeglio, Mark A. Atkinson, Stephanie Woerner, Maria B. Grant

المصدر: Diabetologia
Beam, C A, Beli, E, Wasserfall, C H, Woerner, S E, Legge, M T, Evans-Molina, C, McGrail, K M, Silk, R, Grant, M B, Atkinson, M A & DiMeglio, L A 2021, ' Peripheral immune circadian variation, synchronisation and possible dysrhythmia in established type 1 diabetes ', Diabetologia . https://doi.org/10.1007/s00125-021-05468-6Test

مصطلحات موضوعية: 0301 basic medicine, CD4-Positive T-Lymphocytes, Male, type 1 diabetes, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Circadian clock, CD8-Positive T-Lymphocytes, T-Lymphocytes, Regulatory, Mice, 0302 clinical medicine, Cytotoxic T cell, education.field_of_study, B-Lymphocytes, Immune cells, Flow Cytometry, Circadian Rhythm, Cytokine, Type 1 diabetes, Female, Adult, Adolescent, Period (gene), Population, Biology, Chronobiology Disorders, circadian ryhtms, Article, 03 medical and health sciences, Clinical, Young Adult, Immune system, SDG 3 - Good Health and Well-being, Circadian Clocks, Internal Medicine, medicine, Animals, Humans, Circadian rhythms, Circadian rhythm, Lymphocyte Count, education, Interleukin-6, Dendritic Cells, medicine.disease, Mice, Inbred C57BL, 030104 developmental biology, Diabetes Mellitus, Type 1, Immune System, Immunology, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5304384a2a7eb86434e13bd1acc63ddbTest
http://europepmc.org/articles/PMC8245361Test

4

Suppression of serum lipid transfer proteins involved in high-density lipoprotein cholesterol metabolism by intensive insulin therapy in the first year of type 1 diabetes mellitus: Prospective InLipoDiab1 study

المؤلفون: Agata Grzelka-Woźniak, Aleksandra Uruska, Paweł Niedźwiecki, Aleksandra Cieluch, Justyna Flotyńska, Ewa Wysocka, Dorota Zozulińska-Ziółkiewicz, Marcin Nowicki

المصدر: Nutrition, Metabolism and Cardiovascular Diseases. 31:1219-1226

مصطلحات موضوعية: Adult, Blood Glucose, Male, medicine.medical_specialty, Time Factors, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Medicine (miscellaneous), Pilot Projects, 030209 endocrinology & metabolism, 030204 cardiovascular system & hematology, Young Adult, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, High-density lipoprotein, Phospholipid transfer protein, Internal medicine, Diabetes mellitus, Cholesterylester transfer protein, Humans, Hypoglycemic Agents, Insulin, Medicine, Prospective Studies, Phospholipid Transfer Proteins, Type 1 diabetes, Nutrition and Dietetics, biology, business.industry, Reverse cholesterol transport, medicine.disease, Cholesterol Ester Transfer Proteins, Diabetes Mellitus, Type 1, Treatment Outcome, Endocrinology, chemistry, biology.protein, Female, lipids (amino acids, peptides, and proteins), Cardiology and Cardiovascular Medicine, business, Plant lipid transfer proteins, Biomarkers

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d227254b7b81ce95dcb9f369611a2c09Test
https://doi.org/10.1016/j.numecd.2020.11.006Test

5

Insulin Receptor–Expressing T Cells Appear in Individuals at Risk for Type 1 Diabetes and Can Move into the Pancreas in C57BL/6 Transgenic Mice

المؤلفون: Mark A. Atkinson, Tasneem Al-Huniti, Nirdesh K Gupta, Tian Chen, Jamie L. Felton, James D Horner, Steven K. Lundy, Michael P. Morran, Douglas Rogers, Emily Esakov, Swapnaa Balaji, Andrea Nestor Kalinoski, Neha Nandedkar-Kulkarni, Brigid Gregg, Kanakadurga Singer, Marcia F. McInerney, James D. Bretz

المصدر: J Immunol

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d0b0469b6fd27c7f018eab522859d75Test
https://doi.org/10.4049/jimmunol.1900357Test

6

Identification and characterisation of tertiary lymphoid organs in human type 1 diabetes

المؤلفون: Nadir Kadri, Sarah J. Richardson, Lydia Sorokin, Eva Korpos, Sophie Loismann, Clais R. Findeisen, Noel G. Morgan, Alberto Pugliese, Frank Arfuso, George W. Burke, Marika Bogdani

المصدر: Diabetologia

مصطلحات موضوعية: 0301 basic medicine, Male, Pathology, Endocrinology, Diabetes and Metabolism, Autoimmunity, medicine.disease_cause, Mice, 0302 clinical medicine, Tertiary lymphoid organs, Mice, Inbred NOD, Child, NOD mice, Aged, 80 and over, Middle Aged, medicine.anatomical_structure, Type 1 diabetes, Fibroblastic reticular cells, Child, Preschool, Lymph node, Female, Beta cell, Adult, medicine.medical_specialty, Basement membrane, Adolescent, T cell, High endothelial venules, 030209 endocrinology & metabolism, Biology, Article, 03 medical and health sciences, Islets of Langerhans, Young Adult, Internal Medicine, medicine, Animals, Humans, Pancreas, B cell, Aged, Autoantibodies, Transplantation, medicine.disease, 030104 developmental biology, Diabetes Mellitus, Type 1, Tertiary Lymphoid Structures, Microscopy, Fluorescence, Reticular fibres, Insulitis

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f333af12269efbba20d5e0fefe7a11dfTest
http://europepmc.org/articles/PMC8187221Test

7

Expression of immunoreactive inducible nitric oxide synthase in pancreatic islet cells from newly diagnosed and long-term type 1 diabetic donors is heterogeneous and not disease-associated

المؤلفون: Knut Dahl-Jørgensen, Shiva Reddy, Lars Krogvold, Owen Martin, Charlton Martin, Kevin Xueying Sun, Aamenah Al-Ani

المصدر: Cell and Tissue Research. 384:655-674

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, endocrine system, medicine.medical_specialty, Histology, Adolescent, endocrine system diseases, Nitric Oxide Synthase Type II, Nitric Oxide, Glucagon, Pathology and Forensic Medicine, Proinflammatory cytokine, Nitric oxide, Islets of Langerhans, Young Adult, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Internal medicine, medicine, Humans, Beta (finance), Cells, Cultured, Type 1 diabetes, geography, geography.geographical_feature_category, biology, Chemistry, Cell Biology, medicine.disease, Islet, Nitric oxide synthase, Diabetes Mellitus, Type 1, 030104 developmental biology, Endocrinology, biology.protein, Female, Beta cell, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6728a9832de8ac370bf9e4176fa86c25Test
https://doi.org/10.1007/s00441-020-03340-4Test

8

Human plasma‐derived alpha1‐proteinase inhibitor in patients with new‐onset type 1 diabetes mellitus: A randomized, placebo‐controlled proof‐of‐concept study

المؤلفون: William H. Lagarde, Eva Tsalikian, Kimberly Steinmann, Barry Reiner, Steven M. Willi, Kecia L. Courtney

المصدر: Pediatric Diabetes

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Serine Proteinase Inhibitors, Adolescent, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, 030209 endocrinology & metabolism, Placebo, Gastroenterology, Proof of Concept Study, Drug Administration Schedule, 03 medical and health sciences, chemistry.chemical_compound, Young Adult, 0302 clinical medicine, Internal medicine, Internal Medicine, medicine, Humans, In patient, 030212 general & internal medicine, Dosing, Interleukin 6, Child, Infusions, Intravenous, Type 1 diabetes, biology, C-Peptide, C-peptide, business.industry, C‐peptide, Interleukin-6, Insulin, Type 1 Diabetes: Pathophysiology and Prevention, alpha 1‐proteinase inhibitor, prolastin, medicine.disease, Diabetes Mellitus, Type 1, Treatment Outcome, chemistry, Tolerability, Interleukin‐6, alpha 1-Antitrypsin, Pediatrics, Perinatology and Child Health, biology.protein, Female, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08a4f2a395371627eefdb01a08bfa44aTest
http://europepmc.org/articles/PMC7984376Test

9

A Human Randomized Controlled Trial Comparing Metabolic Responses to Single and Repeated Hypoglycemia in Type 1 Diabetes

المؤلفون: Niels Jessen, Mads Vadsted Svart, Nils E. Magnusson, Thomas Schmidt Voss, Nikolaj Rittig, Julie Støy, Niels Møller, Mads Bengtsen

المصدر: Bengtsen, M B, Støy, J, Rittig, N F, Voss, T S, Magnusson, N E, Svart, M V, Jessen, N & Møller, N 2020, ' A human randomized controlled trial comparing metabolic responses to single and repeated hypoglycemia in type 1 diabetes ', The Journal of clinical endocrinology and metabolism, vol. 105, no. 12, dgaa645 . https://doi.org/10.1210/clinem/dgaa645Test

مصطلحات موضوعية: Adult, Blood Glucose, Male, 0301 basic medicine, medicine.medical_specialty, endocrine system diseases, Denmark, Endocrinology, Diabetes and Metabolism, Glucose uptake, Clinical Biochemistry, 030209 endocrinology & metabolism, Hypoglycemia, Biochemistry, Glucagon, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, Insulin resistance, Recurrence, Internal medicine, medicine, Humans, Insulin, Muscle, Skeletal, Type 1 diabetes, Cross-Over Studies, biology, business.industry, Biochemistry (medical), nutritional and metabolic diseases, Lipid Metabolism, medicine.disease, Subcutaneous Fat, Abdominal, Diabetes Mellitus, Type 1, 030104 developmental biology, Epinephrine, Glucose Clamp Technique, biology.protein, Ketone bodies, Insulin Resistance, business, GLUT4, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06814dcbe5a3bcd2f5f429441a9a120fTest
https://doi.org/10.1210/clinem/dgaa645Test

10

Biomarkers associated with early stages of kidney disease in adolescents with type 1 diabetes

المؤلفون: Andrew Neil, Kim C. Donaghue, Sally M. Marshall, Maria E. Craig, Jennifer J Couper, Paul M. McKeigue, Fergus J. Cameron, Denis Daneman, Timothy W. Jones, Paul Z. Benitez-Aguirre, Marco Colombo, Scott T Chiesa, Elizabeth A. Davis, Helen M. Colhoun, David B. Dunger, M. L. Marcovecchio, John E. Deanfield, Farid H. Mahmud, Raymond Neil Dalton

المصدر: 2020, ' Biomarkers associated with early stages of kidney disease in adolescents with type 1 diabetes ', Pediatric Diabetes . https://doi.org/10.1111/pedi.13095Test

مصطلحات موضوعية: Adult, medicine.medical_specialty, Adolescent, Endocrinology, Diabetes and Metabolism, Renal function, 030209 endocrinology & metabolism, Gastroenterology, Nephropathy, Cohort Studies, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Interquartile range, Internal medicine, Diabetes mellitus, Internal Medicine, medicine, Humans, Diabetic Nephropathies, 030212 general & internal medicine, Cystatin C, Child, Type 1 diabetes, biology, business.industry, Age Factors, Middle Aged, medicine.disease, Fibroblast Growth Factors, Fibroblast Growth Factor-23, Diabetes Mellitus, Type 1, Pediatrics, Perinatology and Child Health, biology.protein, Biomarker (medicine), Osteopontin, Microalbuminuria, Trefoil Factor-3, beta 2-Microglobulin, business, Biomarkers, Glomerular Filtration Rate

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee30256d16fc43d8d9c64c93a523b734Test
https://doi.org/10.1111/pedi.13095Test

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