يعرض 1 - 10 نتائج من 3,589 نتيجة بحث عن '"(1"', وقت الاستعلام: 1.18s تنقيح النتائج
  1. 1
    H3K23/H3K36 hypoacetylation and HDAC1 up-regulation are associated with adverse consequences in obstructive sleep apnea patients

    المؤلفون: Chang-Chun Hsiao, Ting-Ya Wang, Mao-Chang Su, C Lee, Yong-Yong Lin, Meng-Chih Lin, Po-Yuan Hsu, Hsin-Ching Lin, Yung-Che Chen, Chia-Wei Liou, Chien-Hung Chin

    المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
    Scientific Reports

    مصطلحات موضوعية: Male, Jumonji Domain-Containing Histone Demethylases, THP-1 Cells, medicine.medical_treatment, Excessive daytime sleepiness, Histone Deacetylase 1, Diseases, medicine.disease_cause, Cohort Studies, Histones, Medicine, Continuous positive airway pressure, Hypoxia, Promoter Regions, Genetic, Sleep Apnea, Obstructive, Multidisciplinary, biology, Continuous Positive Airway Pressure, Molecular medicine, Intermittent hypoxia, Acetylation, Middle Aged, Up-Regulation, Histone, C-Reactive Protein, NADPH Oxidase 1, Female, medicine.symptom, Adult, medicine.medical_specialty, Polysomnography, Science, Disorders of Excessive Somnolence, Peripheral blood mononuclear cell, Article, Sleep Apnea Syndromes, Medical research, Internal medicine, Humans, business.industry, Snoring, DNA Methylation, medicine.disease, HDAC1, Obstructive sleep apnea, Endocrinology, Case-Control Studies, biology.protein, Leukocytes, Mononuclear, business, Oxidative stress, Biomarkers

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5df41e5c83da43011517e8da1818415Test
    https://doaj.org/article/7aa0ddc6b9dc4f28aa0dbb61d068aad7Test


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  2. 2
    Pembrolizumab Plus Ipilimumab Following Anti-PD-1/L1 Failure in Melanoma

    المؤلفون: Vernon K. Sondak, Andrew Poklepovic, Nikhil I. Khushalani, Jason J. Luke, Sunil Babu, Sigrun Hallmeyer, Zeynep Eroglu, Mario R. Velasco, Emily F. Higgs, Bruce Brockstein, Daniel J Olson, Thomas Krausz, Madhuri Bajaj, Timothy Carll, Riyue Bao, Jose Lutzky, Theodore Karrison, Brian W. Labadie, Thomas F. Gajewski, Yuanyuan Zha

    المصدر: J Clin Oncol

    مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, medicine.medical_treatment, Programmed Cell Death 1 Receptor, Ipilimumab, Pembrolizumab, Antibodies, Monoclonal, Humanized, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, RAPID COMMUNICATIONS, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Melanoma, Language, Aged, Aged, 80 and over, biology, business.industry, Anti pd 1, Immunotherapy, Middle Aged, medicine.disease, 030104 developmental biology, 030220 oncology & carcinogenesis, biology.protein, Female, Antibody, business, medicine.drug

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f53f50387d5994f75ceeba750e8bc2f9Test
    https://doi.org/10.1200/jco.21.00079Test


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  3. 3
    Effect of Primary Systemic Therapy on PD-1, PD-L1, and PD-L2 mRNA Expression in Advanced Breast Cancer

    المؤلفون: Ramadhan Karsono, Muhammad Al Azhar, Siti Nadliroh, Fahreza Saputra, Teguh Aryandono, Yulia Pratiwi

    المصدر: Asian Pacific Journal of Cancer Prevention : APJCP

    مصطلحات موضوعية: Adult, PD-L1, Oncology, medicine.medical_specialty, PD-L2, medicine.medical_treatment, Programmed Cell Death 1 Receptor, Breast Neoplasms, Systemic therapy, B7-H1 Antigen, systemic therapy, breast cancer, Breast cancer, Internal medicine, PD-1, medicine, Humans, RNA, Messenger, Chemotherapy, biology, business.industry, Cancer, General Medicine, Immunotherapy, Middle Aged, Prognosis, Programmed Cell Death 1 Ligand 2 Protein, medicine.disease, Primary tumor, biology.protein, Hormonal therapy, Female, immunotherapy, business, Research Article

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9119c1ae7b363c5f6b60c1cd4dc6aedTest
    https://doi.org/10.31557/apjcp.2021.22.7.2069Test


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  4. 4
    Peripheral immune circadian variation, synchronisation and possible dysrhythmia in established type 1 diabetes

    المؤلفون: Carmella Evans-Molina, Clive Wasserfall, Megan T Legge, Eleni Beli, Craig A. Beam, Ryan Silk, Kieran M. Mcgrail, Linda A. DiMeglio, Mark A. Atkinson, Stephanie Woerner, Maria B. Grant

    المصدر: Diabetologia
    Beam, C A, Beli, E, Wasserfall, C H, Woerner, S E, Legge, M T, Evans-Molina, C, McGrail, K M, Silk, R, Grant, M B, Atkinson, M A & DiMeglio, L A 2021, ' Peripheral immune circadian variation, synchronisation and possible dysrhythmia in established type 1 diabetes ', Diabetologia . https://doi.org/10.1007/s00125-021-05468-6Test

    مصطلحات موضوعية: 0301 basic medicine, CD4-Positive T-Lymphocytes, Male, type 1 diabetes, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Circadian clock, CD8-Positive T-Lymphocytes, T-Lymphocytes, Regulatory, Mice, 0302 clinical medicine, Cytotoxic T cell, education.field_of_study, B-Lymphocytes, Immune cells, Flow Cytometry, Circadian Rhythm, Cytokine, Type 1 diabetes, Female, Adult, Adolescent, Period (gene), Population, Biology, Chronobiology Disorders, circadian ryhtms, Article, 03 medical and health sciences, Clinical, Young Adult, Immune system, SDG 3 - Good Health and Well-being, Circadian Clocks, Internal Medicine, medicine, Animals, Humans, Circadian rhythms, Circadian rhythm, Lymphocyte Count, education, Interleukin-6, Dendritic Cells, medicine.disease, Mice, Inbred C57BL, 030104 developmental biology, Diabetes Mellitus, Type 1, Immune System, Immunology, 030217 neurology & neurosurgery

    وصف الملف: application/pdf

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5304384a2a7eb86434e13bd1acc63ddbTest
    http://europepmc.org/articles/PMC8245361Test


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  5. 5
    Suppression of serum lipid transfer proteins involved in high-density lipoprotein cholesterol metabolism by intensive insulin therapy in the first year of type 1 diabetes mellitus: Prospective InLipoDiab1 study

    المؤلفون: Agata Grzelka-Woźniak, Aleksandra Uruska, Paweł Niedźwiecki, Aleksandra Cieluch, Justyna Flotyńska, Ewa Wysocka, Dorota Zozulińska-Ziółkiewicz, Marcin Nowicki

    المصدر: Nutrition, Metabolism and Cardiovascular Diseases. 31:1219-1226

    مصطلحات موضوعية: Adult, Blood Glucose, Male, medicine.medical_specialty, Time Factors, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Medicine (miscellaneous), Pilot Projects, 030209 endocrinology & metabolism, 030204 cardiovascular system & hematology, Young Adult, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, High-density lipoprotein, Phospholipid transfer protein, Internal medicine, Diabetes mellitus, Cholesterylester transfer protein, Humans, Hypoglycemic Agents, Insulin, Medicine, Prospective Studies, Phospholipid Transfer Proteins, Type 1 diabetes, Nutrition and Dietetics, biology, business.industry, Reverse cholesterol transport, medicine.disease, Cholesterol Ester Transfer Proteins, Diabetes Mellitus, Type 1, Treatment Outcome, Endocrinology, chemistry, biology.protein, Female, lipids (amino acids, peptides, and proteins), Cardiology and Cardiovascular Medicine, business, Plant lipid transfer proteins, Biomarkers

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d227254b7b81ce95dcb9f369611a2c09Test
    https://doi.org/10.1016/j.numecd.2020.11.006Test


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  6. 6
    Insulin Receptor–Expressing T Cells Appear in Individuals at Risk for Type 1 Diabetes and Can Move into the Pancreas in C57BL/6 Transgenic Mice

    المؤلفون: Mark A. Atkinson, Tasneem Al-Huniti, Nirdesh K Gupta, Tian Chen, Jamie L. Felton, James D Horner, Steven K. Lundy, Michael P. Morran, Douglas Rogers, Emily Esakov, Swapnaa Balaji, Andrea Nestor Kalinoski, Neha Nandedkar-Kulkarni, Brigid Gregg, Kanakadurga Singer, Marcia F. McInerney, James D. Bretz

    المصدر: J Immunol

    مصطلحات موضوعية: Adult, Male, Risk, Genetically modified mouse, medicine.medical_specialty, Adolescent, endocrine system diseases, T-Lymphocytes, T cell, medicine.medical_treatment, Immunology, Mice, Transgenic, Article, Mice, Young Adult, Cell Movement, Mice, Inbred NOD, Insulin-Secreting Cells, Internal medicine, medicine, Animals, Humans, Immunology and Allergy, Child, Pancreas, NOD mice, Type 1 diabetes, biology, Chemistry, Insulin, medicine.disease, Receptor, Insulin, Mice, Inbred C57BL, Disease Models, Animal, Insulin receptor, Diabetes Mellitus, Type 1, medicine.anatomical_structure, Endocrinology, biology.protein, Female, Insulitis

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d0b0469b6fd27c7f018eab522859d75Test
    https://doi.org/10.4049/jimmunol.1900357Test


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  7. 7
    Integrin αvβ5 heterodimer is a specific marker of human pancreatic beta cells

    المؤلفون: Jacqueline V. Schiesser, Thomas Loudovaris, Helen E. Thomas, Edouard G. Stanley, Andrew G. Elefanty

    المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
    Scientific Reports

    مصطلحات موضوعية: 0301 basic medicine, Adult, Male, Cell type, medicine.medical_treatment, Science, Cell, Integrin, Gene Expression, Biology, Immunofluorescence, Article, 03 medical and health sciences, 0302 clinical medicine, Insulin-Secreting Cells, medicine, Humans, Insulin, Receptors, Vitronectin, Beta (finance), geography, Multidisciplinary, geography.geographical_feature_category, medicine.diagnostic_test, Cluster of differentiation, Middle Aged, Islet, Gene expression profiling, Cell biology, 030104 developmental biology, medicine.anatomical_structure, Type 1 diabetes, Diabetes Mellitus, Type 1, biology.protein, Medicine, Female, 030217 neurology & neurosurgery, Biomarkers

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::932b8419e0cfd10e677c6085465d5e16Test
    https://doaj.org/article/dcab1ff3fe334cd4b5b2b617cf023918Test


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  8. 8
    Transarterial chemoembolisation enhances programmed death‐1 and programmed death‐ligand 1 expression in hepatocellular carcinoma

    المؤلفون: Olivier Soubrane, Aurélie Beaufrère, Ahmed Montasser, Miguel Albuquerque, Mohamed Bouattour, Valérie Paradis, François Cauchy

    المصدر: Histopathology. 79:36-46

    مصطلحات موضوعية: Adult, Male, 0301 basic medicine, medicine.medical_specialty, Carcinoma, Hepatocellular, Histology, Combination therapy, medicine.medical_treatment, Programmed Cell Death 1 Receptor, Gastroenterology, B7-H1 Antigen, Pathology and Forensic Medicine, Cohort Studies, 03 medical and health sciences, 0302 clinical medicine, PD-L1, Internal medicine, Biomarkers, Tumor, Humans, Medicine, Chemoembolization, Therapeutic, Aged, Aged, 80 and over, biology, business.industry, Liver Neoplasms, General Medicine, Immunotherapy, Middle Aged, HCCS, medicine.disease, 030104 developmental biology, 030220 oncology & carcinogenesis, Hepatocellular carcinoma, biology.protein, Immunohistochemistry, Female, Programmed death 1, Transcriptome, business, Programmed death

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0de3b8190900c797687dcf60d91de283Test
    https://doi.org/10.1111/his.14317Test


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  9. 9
    Ex vivo isolation, expansion and bioengineering of CCR7+CD95-/or CD62L+CD45RA+ tumor infiltrating lymphocytes from acute myeloid leukemia patients’ bone marrow

    المؤلفون: Samiksha Wasnik, Jeffrey Xiao, Chien-Shing Chen, Do Hyun Kim, Mark E. Reeves, David J. Baylink, Ashley Howard, Olivia L. Francis, Hector Moz, Saied Mirshahidi, Huynh Cao, Yi Xu, Guido Marcucci

    المصدر: Neoplasia (New York, N.Y.)
    Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 12, Pp 1252-1260 (2021)

    مصطلحات موضوعية: Male, Cancer Research, medicine.medical_treatment, Cell Separation, Mice, FACS, flow cytometry, T-Lymphocyte Subsets, hemic and lymphatic diseases, PD-1, Medicine, L-Selectin, AML, acute myeloid leukemia, RC254-282, biology, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Myeloid leukemia, hemic and immune systems, Middle Aged, Adoptive Transfer, Adoptive cell therapy, CAR-T, Leukemia, Myeloid, Acute, medicine.anatomical_structure, BMMNC, bone marrow mononuclear cells, CD95, Heterografts, Female, Immunotherapy, Adult, Original article, Receptors, CCR7, CD3, T cell, chemical and pharmacologic phenomena, Bioengineering, Bone Marrow Cells, Peripheral blood mononuclear cell, Lymphocytes, Tumor-Infiltrating, CD62L, CD45RA, Animals, Humans, Bone marrow, fas Receptor, Aged, Programmed cell death protein 1, Acute myeloid leukemia, Tumor-infiltrating lymphocytes, business.industry, HSCs, hematopoietic stem cells, Naïve T, Interleukin, IL, interleukin, TILs, tumor-infiltrating lymphocytes, biology.protein, Cancer research, Tumor-Infiltrating Lymphocytes, BM, bone marrow, Leukocyte Common Antigens, business, Ex vivo, CCR7

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8631938224952c24db64ba170babb9e6Test
    http://europepmc.org/articles/PMC8603025Test


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  10. 10
    Targeting PD-L1 (Programmed death-ligand 1) and inhibiting the expression of IGF2BP2 (Insulin-like growth factor 2 mRNA-binding protein 2) affect the proliferation and apoptosis of hypopharyngeal carcinoma cells

    المؤلفون: Jisheng Liu, Xudong Yang

    المصدر: Bioengineered
    article-version (VoR) Version of Record
    Bioengineered, Vol 12, Iss 1, Pp 7755-7764 (2021)

    مصطلحات موضوعية: Adult, Male, proliferation, medicine.medical_treatment, Cell, Mice, Nude, Apoptosis, Bioengineering, Applied Microbiology and Biotechnology, B7-H1 Antigen, Hypopharyngeal Carcinoma, Mice, Cell Line, Tumor, PD-L1, medicine, Animals, Humans, Viability assay, programmed cell death 1 ligand 1, Aged, Cell Proliferation, Aged, 80 and over, Gene knockdown, Hypopharyngeal Neoplasms, biology, Chemistry, Growth factor, RNA-Binding Proteins, insulin-like growth factor 2 mRNA-binding protein 2, General Medicine, Middle Aged, Xenograft Model Antitumor Assays, medicine.anatomical_structure, Insulin-like growth factor 2, Cancer research, biology.protein, hypopharyngeal carcinoma, TP248.13-248.65, Research Article, Research Paper, Biotechnology

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc5be91fc6698d2c0556a18942a16a3dTest
    https://doi.org/10.1080/21655979.2021.1983278Test


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