المؤلفون: Josef Zamecnik, Johannes A. Hainfellner, Ketharini Senthilkumar, Anand Iyer, Eleonora Aronica, Wim G.M. Spliet, Katarzyna Kotulska, R. Jeroen Pasterkamp, Marco F.M. Hoekman, Floor E. Jansen, James D. Mills, Peter B. Crino, Anna Jansen, Sergiusz Jozwiak, Bart Janssen, Lars von Oerthel, Anika Bongaarts, Jackelien van Scheppingen, Martha Feucht, Peter C. van Rijen, Lieven Lagae, Till S. Zimmer, Jasper J. Anink, Brendon P. Scicluna, David J. Kwiatkowski, Jan A. Gorter, Paolo Curatolo, Angelika Mühlebner, Pavel Krsek

المساهمون: AII - Amsterdam institute for Infection and Immunity, Pathology, AII - Infectious diseases, ANS - Cellular & Molecular Mechanisms, APH - Mental Health, APH - Aging & Later Life, Graduate School, Center of Experimental and Molecular Medicine, Epidemiology and Data Science, Molecular Neuroscience (SILS, FNWI), Cellular and Computational Neuroscience (SILS, FNWI), Faculty of Medicine and Pharmacy, Mental Health and Wellbeing research group, Public Health Sciences, Neurogenetics

المصدر: Scientific reports, 7(1). Nature Publishing Group
Scientific Reports
Scientific Reports, 7:8089. Nature Publishing Group
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Scientific Reports, 7. Nature Publishing Group

مصطلحات موضوعية: 0301 basic medicine, Cortical tubers, Male, Transcription, Genetic, Bioinformatics, Tuberous Sclerosis Complex 1 Protein, Transcriptome, Tuberous sclerosis, Mice, 0302 clinical medicine, Tuberous Sclerosis, Genetics research, Child, Cerebral Cortex, Neurons, Multidisciplinary, Genetic transcription, Middle Aged, Settore MED/39 - Neuropsichiatria Infantile, 3. Good health, medicine.anatomical_structure, Child, Preschool, Medicine, Neurons -- Physiology, Female, Signal Transduction, Adult, Cerebral cortex -- Physiology, congenital, hereditary, and neonatal diseases and abnormalities, Adolescent, Science, Biology, Mechanistic Target of Rapamycin Complex 1, Article, 03 medical and health sciences, Young Adult, microRNA, Tuberous Sclerosis Complex 2 Protein, medicine, Journal Article, Animals, Humans, General, Gene, Epilepsy, RNA, Infant, medicine.disease, Computational biology and bioinformatics, Mice, Inbred C57BL, MicroRNAs, 030104 developmental biology, Mutation, TSC1, TSC2, Neuroscience, 030217 neurology & neurosurgery

وصف الملف: application/pdf; image/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43b61e14723184d80e7ca69458ca3e72Test
https://doi.org/10.1038/s41598-017-06145-8Test

المؤلفون: Salendra Singh, Vasilios Papavasiliou, Catherine R. Dufour, Jane Beith, Ipshita Nandi, Eran R. Andrechek, Virginie Sanguin-Gendreau, Ewan K.A. Millar, Lyndsay Harris, Asier Unciti-Broceta, Mark Basik, Harvey W. Smith, Sandra A O'Toole, Carolin Temps, Vincent van Hoef, Vinay Varadan, Vincent Giguère, Cynthia Lavoie, Matthew R. Swiatnicki, Ola Larsson, Paul Savage, Alison Hirukawa, Kristofferson Tandoc, Jonathan P. Rennhack, Christina I. Selinger, Matthew Leibovitch, Neil O. Carragher, Ana Cristina Vargas Calderon, Ivan Topisirovic, Dongmei Zuo, Morag Park, Caroline Cooper, William J. Muller

المصدر: Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-19 (2019)

مصطلحات موضوعية: 0301 basic medicine, Carcinogenesis, Receptor, ErbB-2, General Physics and Astronomy, 02 engineering and technology, mTORC1, medicine.disease_cause, Epigenesis, Genetic, CSK Tyrosine-Protein Kinase, Mice, Adenosine Triphosphate, Breast cancer, Mice, Inbred NOD, lcsh:Science, Multidisciplinary, biology, EZH2, Polycomb Repressive Complex 2, Middle Aged, 021001 nanoscience & nanotechnology, Cancer metabolism, Mitochondria, Cell biology, src-Family Kinases, Histone methyltransferase, Female, 0210 nano-technology, PRC2, Cell signalling, Proto-oncogene tyrosine-protein kinase Src, Adult, Science, Repressor, Breast Neoplasms, Mice, Transgenic, macromolecular substances, Mechanistic Target of Rapamycin Complex 1, Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Cell Line, Tumor, medicine, Animals, Humans, Enhancer of Zeste Homolog 2 Protein, Mammary Glands, Human, Cancer models, Oncogenes, General Chemistry, Oncogene ErbB2, 030104 developmental biology, Protein Biosynthesis, biology.protein, lcsh:Q

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7882a0583bbf704a1f04931ffa933ae4Test
https://doi.org/10.1038/s41467-019-10681-4Test

المؤلفون: Lei Han, Yu Zhang, Ruijie Yin, Min Yuan, Shengtao Sun, Shikun He, Xiaohua Li, Xiaohui Liu

المصدر: Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)

مصطلحات موضوعية: 0301 basic medicine, Adult, Male, medicine.drug_class, Corneal diseases, medicine.medical_treatment, Intraperitoneal injection, lcsh:Medicine, Histone Deacetylase 1, Article, Microbiology, Pathogenesis, Histones, 03 medical and health sciences, Histone H3, Mice, 0302 clinical medicine, medicine, Animals, Humans, Fungal keratitis, Dimethyl Sulfoxide, lcsh:Science, Aged, Keratitis, Vorinostat, Multidisciplinary, business.industry, Tumor Necrosis Factor-alpha, Histone deacetylase inhibitor, lcsh:R, Acetylation, Chronic inflammation, Eye infection, Middle Aged, medicine.disease, HDAC1, Histone Deacetylase Inhibitors, Mice, Inbred C57BL, Toll-Like Receptor 4, Disease Models, Animal, 030104 developmental biology, Cytokines, Tumor necrosis factor alpha, lcsh:Q, Female, business, Eye Infections, Fungal, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5d06fdaaa469e65586425e81f78799eTest
http://europepmc.org/articles/PMC6614500Test

المؤلفون: Kang Song, Ranran Yan, Yifan Zhang, Shunjuan Wang, Yanqing Yang, Ri-Li Ge, Gang Qi, Bai Zhenzhong, Yan Li

المصدر: Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)

مصطلحات موضوعية: 0301 basic medicine, Adult, Male, animal structures, Adipose Tissue, White, Adipose tissue, lcsh:Medicine, White adipose tissue, Biology, Altitude Sickness, Exosomes, Article, 03 medical and health sciences, Mice, 0302 clinical medicine, Endocrinology, Adipose Tissue, Brown, Fluorodeoxyglucose F18, Positron Emission Tomography Computed Tomography, Brown adipose tissue, microRNA, medicine, Animals, Humans, Receptor, Fibroblast Growth Factor, Type 1, lcsh:Science, Hypoxia, Multidisciplinary, lcsh:R, Metabolism, Microvesicles, Healthy Volunteers, Cell biology, Maillard Reaction, Mice, Inbred C57BL, MicroRNAs, 030104 developmental biology, medicine.anatomical_structure, Fibroblast growth factor receptor, lcsh:Q, Female, Signal transduction, Radiopharmaceuticals, Fat metabolism, 030217 neurology & neurosurgery, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::294c0619f1413e8f80923f50c4fccd11Test
https://pubmed.ncbi.nlm.nih.gov/32873843Test

المؤلفون: Takehiro Suzuki, Yotaro Matsumoto, Chikahisa Mukawa, Tomoya Tsukimi, Jun Wada, Hiroki Tsukamoto, Yuji Oe, Takaaki Abe, Naoto Suzuki, Nobuyuki Takahashi, Tetsuro Matsuhashi, Yuji Owada, Jurgen Heymann, Hiroaki Yamaguchi, Yukako Akiyama, Chitose Suzuki, Paxton Thanai, Ritsumi Saito, Satoshi Shimada, Ching Chin Yang, Tomohiro Nakamura, Fumika Nanto-Hara, Susumu Ogawa, Daisuke Saigusa, Matthew C. Breeggemann, Koichi Kikuchi, Masayuki Yamamoto, Akihiro Matsuo, Yoshitomi Kanemitsu, Jeffrey B. Kopp, Shinji Fukuda, Sadayoshi Ito, Tomoyuki Iwasaki, Yasutoshi Akiyama, Mariko Ichijo, Atsushi Hozawa, Miho Shimizu, Toshihiro Sato, Takafumi Toyohara, Yoshihisa Tomioka, Tomoyoshi Soga, Yoshiaki Ogata, Nariyasu Mano, Koki Mise, Jiro Ogura, Eikan Mishima, Noriko N. Fukuda, Takashi Suzuki, Shizuko Nagao, Kei Asaji, Takashi Wada, Yusuke Ohsaki, Hisato Shima, Hsin Jung Ho, Yoshitsugu Oikawa, Shigeo Kure

المصدر: Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)

مصطلحات موضوعية: 0301 basic medicine, Male, General Physics and Astronomy, Organic Anion Transporters, 02 engineering and technology, Diabetic nephropathy, urologic and male genital diseases, Podocyte, Madin Darby Canine Kidney Cells, Animals, Genetically Modified, Cohort Studies, Mice, Diabetic Nephropathies, Enzyme Inhibitors, lcsh:Science, Tyrosine Phenol-Lyase, Aged, 80 and over, Kidney, Multidisciplinary, Proteinuria, Podocytes, Sulfates, Middle Aged, 021001 nanoscience & nanotechnology, medicine.anatomical_structure, Female, medicine.symptom, 0210 nano-technology, Adult, medicine.medical_specialty, Science, Sulfuric Acid Esters, General Biochemistry, Genetics and Molecular Biology, Streptozocin, Article, Diabetes Mellitus, Experimental, 03 medical and health sciences, Young Adult, Dogs, Diabetes mellitus, Internal medicine, medicine, Diabetes Mellitus, Animals, Metabolomics, Albuminuria, Humans, Aged, business.industry, urogenital system, General Chemistry, medicine.disease, Rats, Gastrointestinal Microbiome, Mice, Inbred C57BL, 030104 developmental biology, Endocrinology, Diabetes Mellitus, Type 1, Early Diagnosis, Diabetes Mellitus, Type 2, lcsh:Q, Microalbuminuria, Microbiome, business, Kidney disease

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f53539ee350baef3ab3064425f4e6578Test
http://europepmc.org/articles/PMC6478834Test

المؤلفون: Liangrong Shi, Weihua Liao, Shunli Dong, Junjun Wang, Changping Wu, Xiao-Dong Li, Hongbing Shi, Chunhui Zhou, Yi Zhang, Ledu Zhou, Xueyin Long, Nianhua Ding, Changli Peng, Yibei Zhu, Xiaohui Wang, Wei Wu

المصدر: Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)

مصطلحات موضوعية: 0301 basic medicine, Male, Myeloid, Neoplasm, Residual, Radiofrequency ablation, Colorectal cancer, medicine.medical_treatment, T-Lymphocytes, Programmed Cell Death 1 Receptor, General Physics and Astronomy, Monocytes, law.invention, Mice, 0302 clinical medicine, Antineoplastic Agents, Immunological, law, lcsh:Science, Chemokine CCL2, Multidisciplinary, Liver Neoplasms, Antibodies, Monoclonal, Middle Aged, Prognosis, Colon cancer, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Disease Progression, Female, Colorectal Neoplasms, Adult, Receptors, CCR2, Science, T cell, CCL2, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Immune system, Immunoediting, Cell Line, Tumor, medicine, Animals, Humans, Aged, Inflammation, Radiofrequency Ablation, business.industry, Tumor Necrosis Factor-alpha, Macrophages, Myeloid-Derived Suppressor Cells, General Chemistry, Immunotherapy, medicine.disease, Disease Models, Animal, 030104 developmental biology, Tumor progression, Cancer research, lcsh:Q, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3f13b27f4dbf0f312a809e3533a26d8Test
https://pubmed.ncbi.nlm.nih.gov/31780645Test

المؤلفون: Tingting Weng, Jianping Jin, Sonja Jameson-Van Houten, Hong Zhang, Takayuki Iriyama, Jessica Li, Rodney E. Kellems, Travis Nemkov, Wei Wang, Leng Han, Yang Xia, Kaiqi Sun, Andrew T. Lovering, Shushan Zhao, Anren Song, Michael R. Blackburn, Kirk C. Hansen, Hongyu Wu, Angelo D'Alessandro, Robert C. Roach, Hong Liu, Yujin Zhang, Colleen G. Julian, Holger K. Eltzschig, Gennady G. Yegutkin, Mikhail Bogdanov, Harry Karmouty-Quintana, William Dowhan, Andrew W. Subudhi

المصدر: Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)

مصطلحات موضوعية: 0301 basic medicine, Male, Adenosine, Erythrocytes, Acclimatization, General Physics and Astronomy, Nucleoside transporter, Altitude Sickness, Equilibrative nucleoside transporter 1, Mice, Ectonucleotidase, Phosphorylation, Hypoxia, 5'-Nucleotidase, Mice, Knockout, Multidisciplinary, biology, Altitude, Effects of high altitude on humans, Healthy Volunteers, Cell biology, Biochemistry, Female, medicine.symptom, medicine.drug, Signal Transduction, Adult, Science, ta3111, GPI-Linked Proteins, Receptor, Adenosine A2B, General Biochemistry, Genetics and Molecular Biology, Article, Equilibrative Nucleoside Transporter 1, 03 medical and health sciences, Young Adult, medicine, Animals, Humans, Ubiquitination, General Chemistry, Hypoxia (medical), Cyclic AMP-Dependent Protein Kinases, Mice, Inbred C57BL, Oxygen, 030104 developmental biology, biology.protein, human activities, Adenosine A2B receptor

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a165b348940e38adb3287bf78640102Test
http://europepmc.org/articles/PMC5309698Test

المؤلفون: Thomas S. Kupper, Ashraful Haque, Nicholas Collins, Sammy Bedoui, Jane Li, Scott N. Mueller, Bethany L. Macleod, William R. Heath, Francis R. Carbone, Ali Zaid, Xiaodong Jiang, Chang Ook Park, Thomas Gebhardt

المصدر: Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Nature Communications

مصطلحات موضوعية: Adult, CD4-Positive T-Lymphocytes, 0301 basic medicine, Adolescent, Lymphocyte, Science, Antigen-Presenting Cells, General Physics and Astronomy, Mice, Transgenic, Inflammation, Herpesvirus 1, Human, CD8-Positive T-Lymphocytes, Biology, Article, General Biochemistry, Genetics and Molecular Biology, CCL5, Interferon-gamma, Mice, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Dermis, Cell Movement, medicine, Animals, Humans, Antigen-presenting cell, Chemokine CCL5, Cell Aggregation, Skin, Mice, Knockout, Multidisciplinary, Herpes Simplex, General Chemistry, Middle Aged, Hair follicle, Cell aggregation, Cell biology, Mice, Inbred C57BL, 030104 developmental biology, medicine.anatomical_structure, Immunology, Female, medicine.symptom, Hair Follicle, Immunologic Memory, CD8, 030215 immunology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7124f2169a6a29cc291be96d7331ef87Test
https://doaj.orgTest/article/9429c534091c48ec9b67d0bb26d4ecdf

المؤلفون: Mark Trentalange, Huiping Dong, Akiko Iwasaki, Kimberly Martinod, Michal Caspi Tal, Albert C. Shaw, Ryan D. Molony, Richard A. Flavell, Angel G. Solis, Peter Staeheli, Robert J. Homer, Denisa D. Wagner, Ruth R. Montgomery, Piotr Bielecki, Subhasis Mohanty, Iris K. Pang, Padmini S. Pillai

المصدر: Science. 352:463-466

مصطلحات موضوعية: Adult, Male, Myxovirus Resistance Proteins, 0301 basic medicine, Neutrophils, Context (language use), Disease, Biology, medicine.disease_cause, Article, Monocytes, Mice, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Orthomyxoviridae Infections, Immunity, Influenza, Human, medicine, Influenza A virus, Animals, Humans, Respiratory Tract Infections, Adaptor Proteins, Signal Transducing, Aged, Aged, 80 and over, Membrane Glycoproteins, Multidisciplinary, Effector, Caspase 1, Inflammasome, Bacterial Infections, Interferon-beta, TLR7, Viral Load, Virology, Caspases, Initiator, Immunity, Innate, 030104 developmental biology, Toll-Like Receptor 7, Caspases, Immunology, Female, Viral load, 030215 immunology, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::856587a398437861ba873b320e970257Test
https://doi.org/10.1126/science.aaf3926Test

المؤلفون: Leonard Shultz, Anette Gabriele Ziegler, Carolin Daniel, Isabelle Serr, Peter Achenbach, F Haupt, A. Knopff, Martin G. Scherm, Eva Maria Sedlmeier, Füsun Gökmen, Richard A. Willis, Rainer W. Fürst

المصدر: Nature Communications, Vol 7, Iss 1, Pp 1-18 (2016)
Nature Communications
Nat. Commun. 7:10991 (2016)

مصطلحات موضوعية: 0301 basic medicine, Male, General Physics and Astronomy, Autoimmunity, medicine.disease_cause, Lymphocyte Activation, Autoantigens, T-Lymphocytes, Regulatory, Immune tolerance, Mice, Medicine, Insulin, CTLA-4 Antigen, Receptors, Immunologic, Child, Vaccines, Multidisciplinary, geography.geographical_feature_category, Effector, Hematopoietic Stem Cell Transplantation, FOXP3, hemic and immune systems, Forkhead Transcription Factors, Islet, 3. Good health, ddc, Vaccination, Haematopoiesis, Self Tolerance, Child, Preschool, Female, Adult, Adolescent, Science, chemical and pharmacologic phenomena, Mice, Transgenic, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Young Adult, TIGIT, HLA-DQ Antigens, Immune Tolerance, Animals, Humans, geography, business.industry, Interleukin-2 Receptor alpha Subunit, General Chemistry, 030104 developmental biology, Diabetes Mellitus, Type 1, Gene Expression Regulation, Immunology, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30c80ee79508d9db1d67e064c7e9837eTest
https://doaj.orgTest/article/384e9f53afaf4353a75ebc119a70470f