-
1
المؤلفون: Hiroyuki Motoyama, Norifumi Kawada, Kohei Kotani, Akihiro Tamori, Naoshi Odagiri, Hideki Fujii, Hoang Hai, Le Thi Thanh Thuy, Atsushi Hagihara, Minh Phuong Dong, Masaru Enomoto, Ritsuzo Kozuka, Etsushi Kawamura, Sawako Uchida-Kobayashi, Kanako Yoshida
المصدر: Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Scientific Reportsمصطلحات موضوعية: Adult, Male, Carcinoma, Hepatocellular, Guanine, Time Factors, Science, Fluoroimmunoassay, Programmed Cell Death 1 Receptor, Antiviral Agents, Article, Hepatitis, Young Adult, Hepatitis B, Chronic, Predictive Value of Tests, Programmed cell death 1, medicine, Humans, Viral hepatitis, Aged, Multidisciplinary, biology, Nucleoside analogue, Hepatology, business.industry, Liver Neoplasms, Gastroenterology, Nucleosides, Middle Aged, medicine.disease, Treatment Outcome, Hepatocellular carcinoma, biology.protein, Cancer research, Medicine, Female, business, Biomarkers, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4450d2a03fa611a7dd2cf18678b8b541Test
https://doaj.orgTest/article /68f24d6e6a1041038229292cc77e750c -
2
المؤلفون: Raymond Evers, Shinji Yamazaki, Loeckie de Zwart
المصدر: CPT: Pharmacometrics & Systems Pharmacology, Vol 11, Iss 1, Pp 55-67 (2022)
CPT: Pharmacometrics & Systems Pharmacologyمصطلحات موضوعية: Quinidine, Adult, Male, Physiologically based pharmacokinetic modelling, Digoxin, endocrine system diseases, Metabolic Clearance Rate, RM1-950, Pharmacology, Models, Biological, Article, Young Adult, Pharmacokinetics, In vivo, medicine, polycyclic compounds, Humans, Pharmacology (medical), Computer Simulation, Drug Interactions, ATP Binding Cassette Transporter, Subfamily B, Member 1, P-glycoprotein, biology, Dose-Response Relationship, Drug, integumentary system, Chemistry, Research, Transporter, Articles, Middle Aged, In vitro, female genital diseases and pregnancy complications, Dabigatran, Intestines, carbohydrates (lipids), Verapamil, Modeling and Simulation, Area Under Curve, biology.protein, Female, Therapeutics. Pharmacology, Itraconazole, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7452e9e21c70c96573c9224133ea1136Test
https://doaj.orgTest/article /85d43d144eb645dc92ef1b14fa39c67c -
3
المؤلفون: Hiroki Takagi, Miyuki Kajiwara, Irene Nowotny, Masanari Shiramoto, Hideya Muto, Wolfgang Schmider, Tatsuya Yoshihara
المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
Scientific Reportsمصطلحات موضوعية: Adult, Blood Glucose, Male, medicine.medical_specialty, Science, Drug development, Article, Insulin aspart, Young Adult, Glucose infusion, Double-Blind Method, Japan, Pharmacokinetics, Internal medicine, medicine, Humans, Hypoglycemic Agents, Potency, Biosimilar Pharmaceuticals, Insulin Aspart, Cross-Over Studies, Multidisciplinary, business.industry, Type 2 diabetes, Middle Aged, Crossover study, Healthy Volunteers, Confidence interval, Type 1 diabetes, Endocrinology, Therapeutic Equivalency, Pharmacodynamics, Medicine, Plasma insulin, Hormonal therapies, business, Biomarkers, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7b35348be8171f6c2a176b21c9b5311Test
https://doaj.orgTest/article /91ffc0df4bcd43f98107227aa96b64ad -
4
المؤلفون: Zhigang Tian, Xiaokun Shen, Rui Sun, Chuang Guo, Binqing Fu, Haiming Wei, Jiabin Li, Dongyao Wang, Ying Ye, Junfei Zhang, Yanyan Liu
المصدر: Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-13 (2021)
Signal Transduction and Targeted Therapyمصطلحات موضوعية: Adult, CD4-Positive T-Lymphocytes, Male, Cell biology, Hepatitis B virus, Cancer Research, Adolescent, QH301-705.5, Programmed Cell Death 1 Receptor, CD8-Positive T-Lymphocytes, medicine.disease_cause, T-Lymphocytes, Regulatory, Article, Young Adult, Hepatitis B, Chronic, Immune system, Interferon, Drug Resistance, Viral, Genetics, medicine, Humans, Cytotoxic T cell, Hepatitis B e Antigens, IL-2 receptor, Biology (General), Aged, business.industry, Interleukin-2 Receptor alpha Subunit, Interferon-alpha, Interferon-Stimulated Gene Factor 3, Middle Aged, Recombinant Proteins, Clinical trial, Gene Expression Regulation, HBeAg, Immunology, Infectious diseases, Interleukin-2, Medicine, Female, business, CD8, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78e45fff313f3e77b83a96cc5ccad309Test
https://doaj.orgTest/article /21b417eb6d294715b19d0a664f3c43a8 -
5
المؤلفون: Lei Zhang, Ziyu Xie, Dianne Torrence, Ping Chi, Cristina R. Antonescu
المصدر: Genes Chromosomes Cancer
مصطلحات موضوعية: Adult, Male, Proto-Oncogene Proteins B-raf, Cancer Research, Oncogene Proteins, Fusion, Gastrointestinal Stromal Tumors, Nerve Tissue Proteins, PDGFRA, medicine.disease_cause, Article, Fusion gene, Young Adult, GTP-Binding Proteins, Genetics, medicine, Humans, Receptor, trkC, Receptor, Fibroblast Growth Factor, Type 1, neoplasms, Anoctamin-1, In Situ Hybridization, Fluorescence, Mutation, GiST, biology, CD117, GTPase-Activating Proteins, Imatinib, Gene rearrangement, Middle Aged, digestive system diseases, Neoplasm Proteins, Gene Expression Regulation, Neoplastic, Proto-Oncogene Proteins c-kit, Ribonucleoproteins, Imatinib Mesylate, Cancer research, biology.protein, Female, Myxoid Leiomyosarcoma, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6025e5a77624d3c37c3deb8d5c5844a8Test
https://doi.org/10.1002/gcc.22991Test -
6
المؤلفون: Bart O. Roep, Nicolas Wisniacki, Rene J. Mclaughlin, Pieter Gillard, Robert Hilbrands, Frans Gorus, João Joaquim Oliveira, Chantal Mathieu, Antonella Napolitano, André van Maurik, Dave Inman, Bart Keymeulen, Rachel M. Gittelman, Ursule Van de Velde
المساهمون: Pathology/molecular and cellular medicine, Diabetes Pathology & Therapy, Diabetes Clinic, Vriendenkring VUB, UZB Other
المصدر: Diabetologia
مصطلحات موضوعية: Adult, Male, Epstein-Barr Virus Infections, medicine.medical_specialty, Adolescent, type 1 diabetes, Endocrinology, Diabetes and Metabolism, Antibodies, Monoclonal, Humanized, Placebo, Article, Young Adult, Anti-CD3 monoclonal antibody, Insulin-Secreting Cells, Internal medicine, Insulin Secretion, Internal Medicine, medicine, Humans, Single-Blind Method, Autoreactive T cell, Adverse effect, Islet autoimmunity, Type 1 diabetes, C-Peptide, Dose-Response Relationship, Drug, business.industry, Epstein–Barr virus reactivation, Otelixizumab, medicine.disease, Cytokine release syndrome, Diabetes Mellitus, Type 1, Tolerability, Tolerability Study, Disease Progression, Latent Infection, Female, business, medicine.drug
وصف الملف: Print-Electronic
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8386442d561c2348c0022ce2589ecd31Test
https://doi.org/10.1007/s00125-020-05317-yTest -
7
المؤلفون: Diana Babaevskaya, Andrey Proshin, Igor Pomytkin, Margarita Oplatchikova, Tatyana Strekalova, Johannes P.J.M. de Munter, D. A. Pavlov, Allan V. Kalueff, Klaus-Peter Lesch, Ekaterina Lysikova, Anna Gorlova, Erik Ch. Wolters, Aleksei Umriukhin
المساهمون: Psychiatrie & Neuropsychologie, RS: MHeNs - R3 - Neuroscience
المصدر: Journal of Cellular and Molecular Medicine, 24(17), 10251-10257. Wiley-Blackwell
Journal of Cellular and Molecular Medicine
J. Cell. Mol. Med.مصطلحات موضوعية: Male, Pathology, amyotrophic lateral sclerosis, PROTEIN EXPRESSION, EXPERIMENTAL NEUROINFLAMMATION, REAL TIME POLYMERASE CHAIN REACTION, MOUSE, ANIMAL EXPERIMENT, stem cell therapy, FUS[1‐359]‐tg mice, Mice, 0302 clinical medicine, SUCROSE PREFERENCE TEST, CELECOXIB, BRAIN, MUTATION, FUS[1-359]-tg mice, Neurons, RNA BINDING PROTEIN FUS, Behavior, Animal, celecoxib, LOCOMOTION, Neurodegeneration, TRANSGENIC MOUSE, Brain, DEPRESSION, Riluzole, Spinal Cord, 030220 oncology & carcinogenesis, RNA ISOLATION, CALCIUM BINDING PROTEIN, DRUG EFFECT, medicine.medical_specialty, Short Communication, Short Communications, FUS PROTEIN, MOUSE, IONIZED CALCIUM BINDING ADAPTOR MOLECULE 1, BEHAVIOR, ANIMAL, INTERLEUKIN-1BETA, NEUROINFLAMMATION, 03 medical and health sciences, TAIL SUSPENSION TEST, NONHUMAN, Social Behavior, ELEVATED PLUS MAZE TEST, INTERLEUKIN 1BETA, FRONTOTEMPORAL LOBAR DEGENERATION, Glycogen Synthase Kinase 3 beta, animal model, ANIMALS, ANIMAL, medicine.disease, FUS[1-359]-TG MICE, Molecular medicine, 030104 developmental biology, Mutation, HIPPOCAMPUS, emotionality and cognition, CYCLOOXYGENASE 1, HOME-CAGE ACTIVITY TEST, ABNORMAL BEHAVIOR, SPINAL CORD, GELATINASE B, CYCLOOXYGENASE 2, 0301 basic medicine, MATRIX METALLOPROTEINASES, NERVE CELL, Interleukin-1beta, Anti-Inflammatory Agents, Hippocampus, PREFRONTAL CORTEX, ANIMAL MODEL, UNCLASSIFIED DRUG, neuroinflammation, MARBLE BURYING TEST, ANXIETY, COGNITIVE DEFECT, TISSUE INHIBITOR OF METALLOPROTEINASE 1, PLASTICITY, Amyotrophic lateral sclerosis, NEURONS, MOLECULAR MARKER, Frontotemporal lobar degeneration, STEM CELL, riluzole, Muscle atrophy, GENOTYPE, ANTIINFLAMMATORY ACTIVITY, frontotemporal lobar degeneration, BIOLOGICAL MARKER, GLYCOGEN SYNTHASE KINASE 3BETA, Molecular Medicine, AMYOTROPHIC LATERAL SCLEROSIS, RNA-BINDING PROTEIN FUS, medicine.symptom, ANTIINFLAMMATORY AGENT, medicine.drug, STEM CELL THERAPY, GLYCOGEN SYNTHASE KINASE 3 BETA, CAGE TEST, METABOLISM, ADULT, INFLAMMATION, WESTERN BLOTTING, ANIMAL TISSUE, GENE MUTATION, OPEN FIELD TEST, EMOTION, medicine, Animals, RESIDENT-INTRUDER TEST, ARTICLE, NERVE DEGENERATION, Neuroinflammation, Inflammation, MALE, TUMOR NECROSIS FACTOR, INTRACEREBROVENTRICULAR DRUG ADMINISTRATION, business.industry, SOCIAL BEHAVIOR, ANTI-INFLAMMATORY AGENTS, Cell Biology, FRONTOTEMPORAL DEMENTIA, ANIMAL BEHAVIOR, EMOTIONALITY AND COGNITION, CONTROLLED STUDY, MICE, GLYCOGEN SYNTHASE KINASE 3ALPHA, Cyclooxygenase 2, RILUZOLE, COGNITION, RNA-Binding Protein FUS, business
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e06827f1ecd2f754817e6fe6568533e8Test
https://cris.maastrichtuniversity.nl/en/publications/0162d1c6-abc0-4610-83d0-566d46a45289Test -
8
المؤلفون: Taleen A. MacArthur, Aodhnait S. Fahy, James W. Jakub
المصدر: Am Surg
مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Skin Neoplasms, Minnesota, Herpesvirus 1, Human, Injections, Intralesional, Article, 030207 dermatology & venereal diseases, 03 medical and health sciences, Antineoplastic Agents, Immunological, 0302 clinical medicine, Fluorodeoxyglucose F18, Surgical oncology, medicine, Humans, Melanoma, Pathological, Aged, Retrospective Studies, Ultrasonography, Fluorodeoxyglucose, Biological Products, medicine.diagnostic_test, business.industry, General Medicine, Middle Aged, medicine.disease, Institutional review board, Combined Modality Therapy, Oncolytic virus, Positron emission tomography, Positron-Emission Tomography, 030220 oncology & carcinogenesis, Radiology, Radiopharmaceuticals, business, Talimogene laherparepvec, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebd00bea70abd7699ee5efae05f43832Test
https://doi.org/10.1177/00031348211023434Test -
9
المؤلفون: J. S. Haw, Michael Mauer, Janet B. McGill, Jill P. Crandall, Bruce A. Perkins, Ruth S. Weinstock, Katherine R. Tuttle, Afshin Parsa, Tom Elliott, Peter Rossing, Amy B. Karger, Amisha Wallia, Cathie Spino, Mark E. Molitch, I. H. de Boer, Maryam Afkarian, David Z.I. Cherney, Sylvia E. Rosas, Irl B. Hirsch, Sarit Polsky, Allison B. Goldfine, Andrzej T. Galecki, Guillermo E. Umpierrez, Ronald J. Sigal, Marlon Pragnell, Ildiko Lingvay, M. L. Caramori, Rodica Pop-Busui, Ronnie Aronson, William N. Robiner, Chun Yi Wu, David M. Maahs, Peter A. Senior, Alessandro Doria
المصدر: N Engl J Med
مصطلحات موضوعية: Adult, Male, Xanthine Oxidase, medicine.medical_specialty, Allopurinol, Urology, Renal function, 030204 cardiovascular system & hematology, Placebo, Article, Renin-Angiotensin System, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Double-Blind Method, Diabetes mellitus, medicine, Humans, Diabetic Nephropathies, Treatment Failure, 030212 general & internal medicine, Enzyme Inhibitors, Aged, Type 1 diabetes, business.industry, General Medicine, Middle Aged, medicine.disease, Uric Acid, Diabetes Mellitus, Type 1, chemistry, Uric acid, Female, Glycated hemoglobin, Iohexol, business, Glomerular Filtration Rate, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab6ef2b59ae2513d4a7415a3b5af846cTest
https://doi.org/10.1056/nejmoa1916624Test -
10
المؤلفون: Kayla J. Wolf, Jonathan Rick, Alan T. Nguyen, Sumedh S. Shah, Harsh Wadhwa, Joseph H Garcia, Sören Müller, Luke A. Gilbert, Garima Yagnik, Sanjay Kumar, Manish K. Aghi, Matheus P. Pereira, Rushikesh S. Joshi, Jung-Ming G. Lin, Jacob Weiss, Aaron Diaz, Saket Jain, William S. Chen, Arman Jahangiri, Ankush Chandra
المصدر: Cancer research, vol 80, iss 7
Cancer Resمصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, Drug Resistance, Angiogenesis Inhibitors, 0302 clinical medicine, Stem Cell Research - Nonembryonic - Human, Phytogenic, Antineoplastic Combined Chemotherapy Protocols, Tumor Microenvironment, 2.1 Biological and endogenous factors, Medicine, Aetiology, Cancer, Tumor, Neovascularization, Pathologic, Brain Neoplasms, Brain, Middle Aged, Phenotype, Cell Hypoxia, Up-Regulation, Gene Expression Regulation, Neoplastic, Bevacizumab, Oncology, 5.1 Pharmaceuticals, 030220 oncology & carcinogenesis, Neoplastic Stem Cells, Female, Development of treatments and therapeutic interventions, Stem cell, medicine.symptom, Biotechnology, medicine.drug, Adult, Programmed cell death, Epithelial-Mesenchymal Transition, Oncology and Carcinogenesis, Antineoplastic Agents, Article, Lignans, Cell Line, Young Adult, 03 medical and health sciences, Rare Diseases, Downregulation and upregulation, Cell Line, Tumor, Human Umbilical Vein Endothelial Cells, Animals, Humans, Neoplasm Invasiveness, Chitinase-3-Like Protein 1, Oncology & Carcinogenesis, Neovascularization, Aged, Pathologic, Neoplastic, business.industry, Microarray analysis techniques, Biphenyl Compounds, Mesenchymal stem cell, Zinc Finger E-box-Binding Homeobox 1, Hypoxia (medical), Stem Cell Research, Antineoplastic Agents, Phytogenic, Xenograft Model Antitumor Assays, Brain Disorders, Brain Cancer, 030104 developmental biology, Gene Expression Regulation, Drug Resistance, Neoplasm, Cancer research, Neoplasm, sense organs, Glioblastoma, business
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31078c3c37cef95ce34f6641ccd4652aTest
https://doi.org/10.1158/0008-5472.can-19-1305Test