نتائج البحث

المصدر: Høgdall, D, O'Rourke, C J, Dehlendorff, C, Larsen, O F, Jensen, L H, Johansen, A Z, Dang, H, Factor, V M, Grunnet, M, Mau-Sørensen, M, Oliveira, D V N P, Linnemann, D, Boisen, M K, Wang, X W, Johansen, J S & Andersen, J B 2020, ' Serum IL6 as a Prognostic Biomarker and IL6R as a Therapeutic Target in Biliary Tract Cancers ', Clinical Cancer Research, vol. 26, no. 21, pp. 5655-5667 . https://doi.org/10.1158/1078-0432.CCR-19-2700Test
Clin Cancer Res

مصطلحات موضوعية: Adult, Male, musculoskeletal diseases, 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, Locally advanced, Inflammation, Deoxycytidine, Article, Disease-Free Survival, Mice, 03 medical and health sciences, 0302 clinical medicine, In vivo, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, Biomarkers, Tumor, medicine, Animals, Humans, Antigens, Tumor-Associated, Carbohydrate, Prognostic biomarker, Chitinase-3-Like Protein 1, Aged, Cell Proliferation, Aged, 80 and over, Interleukin-6, Proportional hazards model, business.industry, Palliative Care, Middle Aged, Prognosis, Receptors, Interleukin-6, Gemcitabine, Progression-Free Survival, Clinical trial, Biliary Tract Neoplasms, 030104 developmental biology, Biliary tract, 030220 oncology & carcinogenesis, Female, medicine.symptom, business, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db1883a3389ee7e27bcc0a6669a1e847Test
https://doi.org/10.1158/1078-0432.ccr-19-2700Test

25

Effect of SLCO1B1 Polymorphisms on High‐Dose Methotrexate Clearance in Children and Young Adults With Leukemia and Lymphoblastic Lymphoma

المؤلفون: Rachael R. Schulte, Sara L. Van Driest, C. Michael Stein, Leena Choi, Richard H. Ho, Nipun Utreja

المصدر: Clinical and Translational Science
Clinical and Translational Science, Vol 14, Iss 1, Pp 343-353 (2021)

مصطلحات موضوعية: Male, 030213 general clinical medicine, Pharmacogenomic Variants, 030226 pharmacology & pharmacy, Gastroenterology, 0302 clinical medicine, General Pharmacology, Toxicology and Pharmaceutics, Young adult, Child, biology, medicine.diagnostic_test, Liver-Specific Organic Anion Transporter 1, lcsh:Public aspects of medicine, General Neuroscience, Articles, General Medicine, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Leukemia, Child, Preschool, Female, medicine.drug, Adult, musculoskeletal diseases, Antimetabolites, Antineoplastic, medicine.medical_specialty, Adolescent, Models, Biological, Polymorphism, Single Nucleotide, Article, General Biochemistry, Genetics and Molecular Biology, Young Adult, 03 medical and health sciences, Pharmacokinetics, Internal medicine, medicine, Humans, Dosing, Dose-Response Relationship, Drug, business.industry, Research, lcsh:RM1-950, Body Weight, Lymphoblastic lymphoma, Infant, lcsh:RA1-1270, medicine.disease, Leukemia, Lymphoid, Pharmacogenomic Testing, lcsh:Therapeutics. Pharmacology, Methotrexate, Therapeutic drug monitoring, biology.protein, SLCO1B1, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72eb3abba07ab7046cb87869cfe4f0d9Test
https://doi.org/10.1111/cts.12879Test

26

Immunologic and tumor responses of pegilodecakin with 5-FU/LV and oxaliplatin (FOLFOX) in pancreatic ductal adenocarcinoma (PDAC)

المصدر: Investigational new drugs, vol 39, iss 1
Invest New Drugs

مصطلحات موضوعية: 0301 basic medicine, Oncology, Organoplatinum Compounds, Metastatic pancreatic adenocarcinoma, Leucovorin, Phases of clinical research, Kaplan-Meier Estimate, Polyethylene Glycols, 0302 clinical medicine, FOLFOX, Antineoplastic Combined Chemotherapy Protocols, Pharmacology (medical), 6.2 Cellular and gene therapies, Cancer, education.field_of_study, Pharmacology and Pharmaceutical Sciences, Middle Aged, Progression-Free Survival, Interleukin-10, Tolerability, Pancreatic Ductal, 6.1 Pharmaceuticals, 030220 oncology & carcinogenesis, IL-10, Fluorouracil, Pegilodecakin, Drug, Carcinoma, Pancreatic Ductal, medicine.drug, Adult, medicine.medical_specialty, Clinical Trials and Supportive Activities, Population, Phase 1, Article, Dose-Response Relationship, Pancreatic Cancer, 03 medical and health sciences, Rare Diseases, Clinical Research, Internal medicine, medicine, Humans, Oncology & Carcinogenesis, Pegylated IL-10, Adverse effect, education, Response Evaluation Criteria in Solid Tumors, Neoplasm Staging, Aged, Pharmacology, Dose-Response Relationship, Drug, business.industry, Carcinoma, Evaluation of treatments and therapeutic interventions, digestive system diseases, Oxaliplatin, Pancreatic Neoplasms, Regimen, 030104 developmental biology, Tumor progression, Digestive Diseases, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d69d0ddd9f3551a8ca0a4d0daab7d846Test
https://doi.org/10.1007/s10637-020-01000-6Test

27

Characterization of Fibroblasts in Iatrogenic Laryngotracheal Stenosis and Type II Diabetes Mellitus

المؤلفون: Alexander T. Hillel, Ruth J. Davis, Hsiu-Wen Tsai, Kevin M. Motz, Dacheng Ding, Ioan A. Lina

المصدر: Laryngoscope

مصطلحات موضوعية: Male, endocrine system diseases, Biopsy, Iatrogenic Disease, Constriction, Pathologic, Phenformin, Oxidative Phosphorylation, chemistry.chemical_compound, Tracheostomy, 0302 clinical medicine, Myofibroblasts, 030223 otorhinolaryngology, Cells, Cultured, biology, Middle Aged, Metformin, Trachea, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Amobarbital, Female, Tracheal Stenosis, Glycolysis, Myofibroblast, Muscle Contraction, medicine.drug, Adult, Glottis, medicine.medical_specialty, Primary Cell Culture, Article, Contractility, Cicatrix, Young Adult, 03 medical and health sciences, Internal medicine, Intubation, Intratracheal, medicine, Humans, Hypoglycemic Agents, Fibroblast, Aged, Cell Proliferation, business.industry, nutritional and metabolic diseases, Laryngostenosis, Fibronectin, Collagen, type I, alpha 1, Endocrinology, Diabetes Mellitus, Type 2, Otorhinolaryngology, chemistry, Case-Control Studies, biology.protein, Energy Metabolism, business, Ex vivo

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91d48ca1ac1d15b39afc6fb0f8868387Test
https://doi.org/10.1002/lary.29026Test

28

Effect of drug metabolizing enzymes and transporters in Thai colorectal cancer patients treated with irinotecan-based chemotherapy

المؤلفون: Apichaya Puangpetch, Phichai Chansriwong, Ekaphop Sirachainan, Suwannee Sirilerttrakul, Chonlaphat Sukasem, Monpat Chamnanphon, Thanyanan Reungwetwattana, Chalirmporn Atasilp

المصدر: Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports

مصطلحات موضوعية: 0301 basic medicine, Oncology, Male, Genetic testing, Colorectal cancer, lcsh:Medicine, 0302 clinical medicine, Gene Frequency, Genetics research, Cytochrome P-450 CYP3A, Glucuronosyltransferase, lcsh:Science, Multidisciplinary, Molecular medicine, Middle Aged, Thailand, Multidrug Resistance-Associated Protein 2, Population study, Female, Multidrug Resistance-Associated Proteins, Colorectal Neoplasms, medicine.drug, Adult, medicine.medical_specialty, Neutropenia, Genotype, Irinotecan, Article, 03 medical and health sciences, Internal medicine, medicine, Humans, ATP Binding Cassette Transporter, Subfamily B, Member 1, CYP3A5, Allele frequency, Alleles, Aged, Polymorphism, Genetic, business.industry, lcsh:R, Genetic Variation, Membrane Transport Proteins, medicine.disease, Personalized medicine, Genotype frequency, 030104 developmental biology, Genetic markers, DPYD, ATP-Binding Cassette Transporters, lcsh:Q, business, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cd7951ea617b032dfd1c624b20a74d5Test
http://link.springer.comTest/article/10.1038/s41598-020-70351-0

29

Increased Expression of 11β-Hydroxysteroid Dehydrogenase Type 1 Contributes to Epidermal Permeability Barrier Dysfunction in Aged Skin

المؤلفون: Noo Ri Lee, Beom Jun Kim, Kyong Oh Shin, Eun Jung Kim, Gareth G. Lavery, Hyun Jee Hwang, Kyungho Park, Young Bin Lee, Solam Lee, Chung Hyeok Lee, Eung Ho Choi, Sung Jay Choe

المصدر: International Journal of Molecular Sciences
Volume 22
Issue 11
International Journal of Molecular Sciences, Vol 22, Iss 5750, p 5750 (2021)

مصطلحات موضوعية: 0301 basic medicine, Male, 11-beta-hydroxysteroid dehydrogenase type 1, 030207 dermatology & venereal diseases, chemistry.chemical_compound, Mice, 0302 clinical medicine, Corticosterone, 11β-hydroxysteroid dehydrogenase type 1, Biology (General), Spectroscopy, Barrier function, Mice, Knockout, biology, integumentary system, glucocorticoids, General Medicine, Middle Aged, Computer Science Applications, Chemistry, Knockout mouse, Cytokines, Female, Inflammation Mediators, hormones, hormone substitutes, and hormone antagonists, medicine.drug, Adult, medicine.medical_specialty, endocrine system, QH301-705.5, Catalysis, Permeability, Article, Inorganic Chemistry, 03 medical and health sciences, Young Adult, Lipid biosynthesis, Internal medicine, medicine, Animals, Humans, Physical and Theoretical Chemistry, Molecular Biology, QD1-999, Aged, Transepidermal water loss, Organic Chemistry, Hairless, Skin Aging, 030104 developmental biology, Endocrinology, chemistry, Gene Expression Regulation, biology.protein, Cortisone, Epidermis, barrier function, Biomarkers, epidermal lipids

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f8084c8f5c816d4e38a571e81ad199fTest
https://pubmed.ncbi.nlm.nih.gov/34072239Test

30

Hypovitaminosis D Is Associated with Higher Levels of Inflammatory Cytokines and with HAM/TSP in HTLV-Infected Patients

المؤلفون: Elaine Coutinho Netto, Carlos Brites, Alfredo Carlos Silva, Celia Pedroso

المصدر: Viruses
Viruses, Vol 13, Iss 2223, p 2223 (2021)
Volume 13
Issue 11

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Calcitriol, viruses, vitamin D, Asymptomatic, Gastroenterology, Microbiology, Article, Pathogenesis, Myelopathy, Immune system, immune system diseases, Virology, Internal medicine, hemic and lymphatic diseases, Tropical spastic paraparesis, Vitamin D and neurology, Prevalence, Medicine, Humans, Aged, Inflammation, Human T-lymphotropic virus 1, 25(OH)D, business.industry, virus diseases, Middle Aged, HTLV, medicine.disease, Vitamin D Deficiency, HTLV-I Infections, QR1-502, Paraparesis, Tropical Spastic, Infectious Diseases, Cross-Sectional Studies, Carrier State, Cytokines, Female, medicine.symptom, business, HAM/TSP, Asymptomatic carrier, Brazil, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea2da569c6def21f630962cf38ab161cTest
http://europepmc.org/articles/PMC8623239Test

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