نتائج البحث

المصدر: Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Engel, D F, Bobbo, V C D, Solon, C S, Nogueira, G A, Moura-Assis, A, Mendes, N F, Zanesco, A M, Papangelis, A, Ulven, T & Velloso, L A 2020, ' Activation of GPR40 induces hypothalamic neurogenesis through p38-and BDNF-dependent mechanisms ', Scientific Reports, vol. 10, no. 1, 11047 . https://doi.org/10.1038/s41598-020-68110-2Test

مصطلحات موضوعية: Male, STRESS, Pyridines, lcsh:Medicine, Ligands, Adult neurogenesis, p38 Mitogen-Activated Protein Kinases, Receptors, G-Protein-Coupled, Mice, Neurotrophic factors, Receptor, lcsh:Science, Neurons, Multidisciplinary, biology, Chemistry, Neurogenesis, Imidazoles, Neurochemistry, Cell biology, OBESITY, POMC NEURONS, FATTY-ACIDS, STEM-CELLS, endocrine system, Cell Survival, p38 mitogen-activated protein kinases, Models, Neurological, Hypothalamus, Article, Cell Line, Methylamines, ADULT, DIETARY, Neurosphere, Free fatty acid receptor 1, Animals, Protein Kinase Inhibitors, Cell Proliferation, Cell growth, Interleukin-6, Brain-Derived Neurotrophic Factor, lcsh:R, PROTEIN-KINASE, Doublecortin, Mice, Inbred C57BL, MICE, biology.protein, lcsh:Q, Propionates, NEUROTROPHIC FACTOR

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f66eba08413780d00163a93b89857e3cTest
http://link.springer.comTest/article/10.1038/s41598-020-68110-2

5

PHD1 controls muscle mTORC1 in a hydroxylation-independent manner by stabilizing leucyl tRNA synthetase

المؤلفون: Peter Carmeliet, Louise Deldicque, Sunghoon Kim, Shimin Zhao, Leigh Breen, Gillian Fitzgerald, Koen Veys, Peppi Koivunen, Benoit Smeuninx, Inés Soro-Arnaiz, Katrien De Bock, Bert Blaauw, Gommaar D'Hulst, Evi Masschelein

المساهمون: UCL - SSS/IONS/CEMO - Pôle Cellulaire et moléculaire

المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature communications, vol 11, iss 1
Nature Communications, 11
Nature Communications
Nature Communications, Vol. 11, no. 1, p. 174 (2020)

مصطلحات موضوعية: 0301 basic medicine, Male, Aging, Regulator, General Physics and Astronomy, mTORC1, Inbred C57BL, Muscle Development, Hydroxylation, chemistry.chemical_compound, Mice, 0302 clinical medicine, Amino Acids, lcsh:Science, Mice, Knockout, chemistry.chemical_classification, Multidisciplinary, Muscles, Amino acid, Cell biology, Mechanisms of disease, TOR signalling, Female, Leucine, Signal transduction, biological phenomena, cell phenomena, and immunity, Signal Transduction, Gene isoform, Adult, Knockout, Science, Procollagen-Proline Dioxygenase, Genetics and Molecular Biology, Mechanistic Target of Rapamycin Complex 1, Article, General Biochemistry, Genetics and Molecular Biology, Hypoxia-Inducible Factor-Proline Dioxygenases, 03 medical and health sciences, Clinical Research, Animals, Humans, Aged, Animal, Leucyl-tRNA synthetase, General Chemistry, Mice, Inbred C57BL, Oxygen, Disease Models, Animal, 030104 developmental biology, HEK293 Cells, chemistry, Preclinical research, General Biochemistry, Disease Models, lcsh:Q, Leucine-tRNA Ligase, 030217 neurology & neurosurgery

وصف الملف: Electronic; application/pdf; application/application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed65d3a9ba21caa35226b725b5c4e464Test
https://doaj.orgTest/article/57ce964136154da49cd0e8f1b72242c1

6

The short isoform of extended synaptotagmin-2 controls Ca2+ dynamics in T cells via interaction with STIM1

المؤلفون: Yousang Gwack, Jin Seok Woo, Zuoming Sun, Sonal Srikanth

المصدر: Scientific reports, vol 10, iss 1
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports

مصطلحات موضوعية: 0301 basic medicine, Adult, ORAI1 Protein, Molecular biology, Physiology, medicine.medical_treatment, T cell, T-Lymphocytes, Cells, 1.1 Normal biological development and functioning, lcsh:Medicine, Jurkat cells, Article, Synaptotagmin 1, 03 medical and health sciences, Jurkat Cells, Synaptotagmins, 0302 clinical medicine, Underpinning research, medicine, Humans, 2.1 Biological and endogenous factors, Calcium Signaling, Stromal Interaction Molecule 1, Aetiology, lcsh:Science, Cells, Cultured, Multidisciplinary, Cultured, ORAI1, Chemistry, Endoplasmic reticulum, T-cell receptor, lcsh:R, STIM1, Calcium Release Activated Calcium Channels, Cell biology, Neoplasm Proteins, 030104 developmental biology, Cytokine, medicine.anatomical_structure, HEK293 Cells, Hela Cells, lcsh:Q, Generic health relevance, 030217 neurology & neurosurgery, HeLa Cells, Protein Binding

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f4e9863e948ad94f8fe120fc10f9426Test
https://escholarship.org/uc/item/6nd0b6t5Test

7

MicroRNA-513b-5p targets COL1A1 and COL1A2 associated with the formation and rupture of intracranial aneurysm

المؤلفون: Qiong Cheng, Zheng Zheng, Yan Chen, Yin-zhou Wang, Yongkun Li

المصدر: Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)

مصطلحات موضوعية: 0301 basic medicine, musculoskeletal diseases, Adult, Male, Programmed cell death, MMP3, congenital, hereditary, and neonatal diseases and abnormalities, Cell biology, MMP2, Molecular biology, Science, Myocytes, Smooth Muscle, Gene Expression, macromolecular substances, MMP9, Aneurysm, Ruptured, Article, Collagen Type I, Cell Line, 03 medical and health sciences, Young Adult, 0302 clinical medicine, microRNA, Genetics, Gene silencing, Humans, skin and connective tissue diseases, Genetic Association Studies, Aged, Aged, 80 and over, Multidisciplinary, integumentary system, Cell growth, Chemistry, Intracranial Aneurysm, Middle Aged, Collagen Type I, alpha 1 Chain, MicroRNAs, 030104 developmental biology, Apoptosis, Cancer research, Medicine, Female, 030217 neurology & neurosurgery, Biomarkers

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e176c27698e923f56beab38ba11573ecTest
http://europepmc.org/articles/PMC8295310Test

8

Fms-like tyrosine kinase 3-internal tandem duplications epigenetically activates checkpoint kinase 1 in acute myeloid leukemia cells

المؤلفون: Lingli Yuan, Yudong Zhang

المصدر: Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Cell biology, Chromatin Immunoprecipitation, animal structures, Adolescent, Molecular biology, Science, Blotting, Western, Apoptosis, Biology, Article, Epigenesis, Genetic, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Gene Duplication, hemic and lymphatic diseases, Humans, Epigenetics, CHEK1, Cancer, Aged, Gene knockdown, Multidisciplinary, Cell growth, Myeloid leukemia, Middle Aged, Enzyme Activation, Leukemia, Myeloid, Acute, 030104 developmental biology, Oncology, fms-Like Tyrosine Kinase 3, Tandem Repeat Sequences, 030220 oncology & carcinogenesis, Checkpoint Kinase 1, embryonic structures, Fms-Like Tyrosine Kinase 3, Cancer research, Medicine, Female, biological phenomena, cell phenomena, and immunity, Tyrosine kinase, psychological phenomena and processes

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::994cf308c63e21410626e75ca81d7cbbTest
https://doi.org/10.1038/s41598-021-92566-5Test

9

High proliferation and delamination during skin epidermal stratification

المؤلفون: Ekaterina Soroka, Lisa Wirtz, Houda Khatif, Christian Kukat, Mareike Damen, Hisham Bazzi, Benjamin D. Simons

المساهمون: Wirtz, Lisa [0000-0001-9967-6729], Kukat, Christian [0000-0003-1508-0229], Simons, Benjamin D [0000-0002-3875-7071], Bazzi, Hisham [0000-0001-8388-4005], Apollo - University of Cambridge Repository, Simons, Benjamin D. [0000-0002-3875-7071]

المصدر: Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)

مصطلحات موضوعية: 0301 basic medicine, Keratinocytes, Male, Cell division, 631/80/128/1965, General Physics and Astronomy, 96/31, Mice, 0302 clinical medicine, Skin Physiological Phenomena, Asymmetric cell division, 14/19, Child, Tissue homeostasis, Mice, Knockout, Multidisciplinary, Cell Differentiation, Middle Aged, Cell biology, medicine.anatomical_structure, Child, Preschool, 631/208/135, 64/60, Female, Keratinocyte, 82/1, Tumor Suppressor p53-Binding Protein 1, Hair Follicle, Ubiquitin Thiolesterase, Adult, Adolescent, Science, 631/80/641, Spindle Apparatus, Biology, Development, Models, Biological, Time-Lapse Imaging, General Biochemistry, Genetics and Molecular Biology, Article, 38/91, 03 medical and health sciences, Young Adult, medicine, Animals, Humans, 631/80/128/1383, Cilia, Mitosis, Cell Proliferation, Aged, Centrosome, Asymmetric Cell Division, General Chemistry, Hair follicle, Embryo, Mammalian, 631/136/2091, Spindle apparatus, 030104 developmental biology, Epidermis, Tumor Suppressor Protein p53, 030217 neurology & neurosurgery

وصف الملف: application/pdf; application/zip; text/xml

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24baa0f4979d3f5d8ead1cc7145e9056Test
https://www.repository.cam.ac.uk/handle/1810/324614Test

10

HNF1A regulates colorectal cancer progression and drug resistance as a downstream of POU5F1

المؤلفون: Norikatsu Miyoshi, Masayuki Ohue, Shiki Fujino, Mamoru Uemura, Aya Ito, Tsunekazu Mizushima, Masayoshi Yasui, Chu Matsuda, Yuichiro Doki, Hidetoshi Eguchi

المصدر: Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)

مصطلحات موضوعية: Male, Colorectal cancer, Apoptosis, Drug resistance, Mice, Hepatocyte Nuclear Factor 1-alpha, Induced pluripotent stem cell, Cancer, Aged, 80 and over, Glucose Transporter Type 1, Multidisciplinary, biology, Middle Aged, Gene Expression Regulation, Neoplastic, Chemotherapy, Adjuvant, Gene Knockdown Techniques, Disease Progression, Medicine, Female, Colorectal Neoplasms, Adult, endocrine system, Cell biology, Adolescent, Science, Primary Cell Culture, Article, Disease-Free Survival, Young Adult, Cell Line, Tumor, medicine, Animals, Humans, Aged, Cell Proliferation, Cell growth, business.industry, medicine.disease, Xenograft Model Antitumor Assays, Multiple drug resistance, HIF1A, Drug Resistance, Neoplasm, Cancer research, biology.protein, GLUT1, business, Octamer Transcription Factor-3, Follow-Up Studies

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbba406b77752877f49b0f5b5919ed40Test
http://europepmc.org/articles/PMC8121855Test

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