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المؤلفون: Sapna Pradyuman Patel, David S. Hong, Vivek Subbiah, Amanda Johnston, Siqing Fu, John S. Bomalaski, Sarina Anne Piha-Paul, Shuyang Yao, Ahmed Kaseb, Aung Naing, Nai Shi, Filip Janku, Apostolia Maria Tsimberidou, Shannon N. Westin, John Stewart
المصدر: Br J Cancer
مصطلحات موضوعية: Adult, Male, Cancer Research, Arginine, Hydrolases, Pharmacology, Article, Polyethylene Glycols, Young Adult, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, In vivo, Neoplasms, Antineoplastic Combined Chemotherapy Protocols, Citrulline, Humans, Medicine, Melanoma, Arginine deiminase, Aged, Aged, 80 and over, Salvage Therapy, Cisplatin, business.industry, Middle Aged, Prognosis, Survival Rate, Argininosuccinate Synthetase 1, Oncology, chemistry, Tolerability, 030220 oncology & carcinogenesis, Toxicity, Female, business, Follow-Up Studies, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d35421e6155a20aeb943eeead2c5143Test
https://doi.org/10.1038/s41416-020-01230-8Test -
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المؤلفون: Erika Cecchin, Giuseppe Toffoli, Federico Innocenti, Alan Forrest, Deborah A. Nickerson, Amy S. Etheridge, Nancy J. Cox, Spinel Karas, Robert R. Bies, Karen L. Mohlke, Ron H.J. Mathijssen
المساهمون: Medical Oncology
المصدر: British Journal of Cancer, 126(4), 640-651. Nature Publishing Group
Br J Cancerمصطلحات موضوعية: Oncology, Adult, Male, Cancer Research, medicine.medical_specialty, Bevacizumab, Pharmacogenomic Variants, Bilirubin, Population, Irinotecan, Polymorphism, Single Nucleotide, Article, chemistry.chemical_compound, Pharmacokinetics, SDG 3 - Good Health and Well-being, Internal medicine, Neoplasms, Genotype, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Glucuronosyltransferase, education, Aged, Aged, 80 and over, education.field_of_study, Clinical Trials as Topic, biology, business.industry, Liver-Specific Organic Anion Transporter 1, Cancer, High-Throughput Nucleotide Sequencing, Sequence Analysis, DNA, Middle Aged, medicine.disease, digestive system diseases, ErbB Receptors, chemistry, biology.protein, Administration, Intravenous, Female, business, SLCO1B1, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62ea219d07ad99d5cc228e98f7bdd0c6Test
https://pure.eur.nl/en/publications/3ab53839-bab3-4d00-bf51-f5c07b5d3416Test -
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المؤلفون: Muhammad Ahmed, Waleed H. Malki, Imran Shahid, Ashraf N. Abdalla, Mohammad Akbar Hossain, Amal Qattan
المصدر: Molecules
Volume 25
Issue 20
Molecules, Vol 25, Iss 4606, p 4606 (2020)مصطلحات موضوعية: cyclin D1, Pharmaceutical Science, Pyridinium Compounds, Analytical Chemistry, chemistry.chemical_compound, 0302 clinical medicine, Drug Discovery, 0303 health sciences, biology, Cell Cycle, Indolizines, Middle Aged, Chemistry (miscellaneous), 030220 oncology & carcinogenesis, MCF-7 Cells, Molecular Medicine, medicine.drug, Adult, CDK2, kinase activity profiling, Breast Neoplasms, Hsp90, Article, Cell Line, Cyclic N-Oxides, lcsh:QD241-441, 03 medical and health sciences, Cyclin D1, lcsh:Organic chemistry, Cyclin-dependent kinase, medicine, Humans, HSP90 Heat-Shock Proteins, Physical and Theoretical Chemistry, Dinaciclib, Kinase activity, PI3K/AKT/mTOR pathway, 030304 developmental biology, Aged, business.industry, Phospholipase C gamma, Organic Chemistry, Cyclin-dependent kinase 2, Cyclin-Dependent Kinase 2, Vascular Endothelial Growth Factor Receptor-2, VEGFR-2, Focal Adhesion Kinase 2, chemistry, Focal Adhesion Kinase 1, Cancer cell, biology.protein, Cancer research, luminal-A breast cancer, business, Tamoxifen
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e32cc0819b70b9392948725ef2611ee6Test
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المؤلفون: Stefan Wirths, Alina Muenchow, Frank Essmann, Walter E. Aulitzky, Elke Malenke, Sandra Weller, Klaus Schulze-Osthoff, Clemens Hinterleitner, Hans-Georg Kopp, Stefanie Bugl, Martin Müller
المصدر: Cell Death & Disease
Cell Death and Disease, Vol 11, Iss 8, Pp 1-12 (2020)مصطلحات موضوعية: Adult, Male, Proteasome Endopeptidase Complex, Cancer Research, Combination therapy, Immunology, bcl-X Protein, Apoptosis, Antineoplastic Agents, Article, Bortezomib, Nitrophenols, Stress signalling, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Targeted therapies, Cell Line, Tumor, medicine, Humans, lcsh:QH573-671, Aged, bcl-2-Associated X Protein, Sulfonamides, lcsh:Cytology, Effector, Chemistry, Venetoclax, Biphenyl Compounds, Sarcoma, Drug Synergism, Cell Biology, Middle Aged, Bridged Bicyclo Compounds, Heterocyclic, medicine.disease, Cancer therapeutic resistance, Proto-Oncogene Proteins c-bcl-2, Proteasome, Cancer research, Proteasome inhibitor, Myeloid Cell Leukemia Sequence 1 Protein, Female, Apoptosis Regulatory Proteins, Proteasome Inhibitors, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81320a70c0a9bb5a399dd5a6ddacea20Test
https://doi.org/10.1038/s41419-020-02910-2Test -
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المؤلفون: Cheng Ying Hsieh, Joen Rong Sheu, Wei Lin Chen, Chih Hao Yang, Jie Heng Tsai, Chi Li Chung
المصدر: International Journal of Molecular Sciences, Vol 20, Iss 20, p 5076 (2019)
International Journal of Molecular Sciences
Volume 20
Issue 20مصطلحات موضوعية: 0301 basic medicine, Male, Mesoderm, lcsh:Chemistry, chemistry.chemical_compound, Mice, Phosphatidylinositol 3-Kinases, 0302 clinical medicine, lcsh:QH301-705.5, Spectroscopy, Aged, 80 and over, mesothelial–mesenchymal transition, biology, General Medicine, Exudates and Transudates, Middle Aged, respiratory system, thrombin, Computer Science Applications, Effusion, Plasminogen activator inhibitor-1, Pleura, plasminogen activator inhibitor-1, Female, pleural fibrosis, residual pleura thickening, medicine.drug, Signal Transduction, Adult, tuberculous pleural fibrosis, Catalysis, Article, Inorganic Chemistry, 03 medical and health sciences, Tissue factor, Young Adult, Thrombin, In vivo, Plasminogen Activator Inhibitor 1, medicine, Animals, Humans, Tuberculosis, Receptor, PAR-1, Physical and Theoretical Chemistry, tuberculous pleural effusion, Molecular Biology, Aged, business.industry, Organic Chemistry, Mycobacterium tuberculosis, Fibrosis, In vitro, respiratory tract diseases, Fibronectin, Mice, Inbred C57BL, Pleural Effusion, Disease Models, Animal, pleural mesothelial cell, 030104 developmental biology, 030228 respiratory system, chemistry, lcsh:Biology (General), lcsh:QD1-999, biology.protein, Cancer research, business, Plasminogen activator, Follow-Up Studies
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::898ef521247c15109b0023fa414edec8Test
https://www.mdpi.com/1422-0067/20/20/5076Test -
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المؤلفون: Xudong Wang, Zhen Fan, Yun Hong, Songbo Qiu, Qiang Li, Yang Lu, Lun Zhang, Bharat Kumar Reddy Chaganty, Jingtao Luo
المصدر: Cancer Letters. 384:39-49
مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, Time Factors, Cetuximab, AMP-Activated Protein Kinases, chemistry.chemical_compound, 0302 clinical medicine, AMP-activated protein kinase, Antineoplastic Combined Chemotherapy Protocols, Enzyme Inhibitors, Phosphorylation, Aged, 80 and over, biology, Middle Aged, Warburg effect, Oncology, Head and Neck Neoplasms, 030220 oncology & carcinogenesis, Carcinoma, Squamous Cell, Female, RNA Interference, Growth inhibition, Glycolysis, Signal Transduction, medicine.drug, Adult, medicine.medical_specialty, Cell Survival, Lipolysis, Mice, Nude, Antineoplastic Agents, Transfection, Article, 03 medical and health sciences, Cell Line, Tumor, Internal medicine, medicine, Animals, Humans, neoplasms, Aged, Cell Proliferation, Squamous Cell Carcinoma of Head and Neck, Acetyl-CoA carboxylase, AMPK, Hypoxia-Inducible Factor 1, alpha Subunit, medicine.disease, Xenograft Model Antitumor Assays, Head and neck squamous-cell carcinoma, digestive system diseases, stomatognathic diseases, 030104 developmental biology, Endocrinology, chemistry, Drug Resistance, Neoplasm, Mutation, Cancer cell, biology.protein, Cancer research, Acetyl-CoA Carboxylase
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dad900499e77c47425cec0285c8dd3fTest
https://doi.org/10.1016/j.canlet.2016.09.020Test -
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المؤلفون: Sang-Yeob Kim, Min-Hee Ryu, Yoon-Koo Kang, Chan Young Ock, Yeon-Mi Ryu, Changhoon Yoo, Jihun Kim
المصدر: British Journal of Cancer
مصطلحات موضوعية: Male, Cancer Research, LAG3, Pyridines, Programmed Cell Death 1 Receptor, Angiogenesis Inhibitors, Gastroenterology, Tyrosine-kinase inhibitor, B7-H1 Antigen, chemistry.chemical_compound, 0302 clinical medicine, Sunitinib, Tumor Microenvironment, Receptors, Immunologic, Hepatitis A Virus Cellular Receptor 2, 0303 health sciences, biology, Neovascularization, Pathologic, CD68, Sarcoma, Middle Aged, Gene Expression Regulation, Neoplastic, Oncology, 030220 oncology & carcinogenesis, Imatinib Mesylate, Female, RNA Interference, medicine.drug, Adult, Cancer microenvironment, medicine.medical_specialty, medicine.drug_class, Gastrointestinal Stromal Tumors, CD3, Article, 03 medical and health sciences, TIGIT, Internal medicine, Regorafenib, medicine, Humans, Protein Kinase Inhibitors, 030304 developmental biology, Aged, Neoplasm Staging, business.industry, Phenylurea Compounds, medicine.disease, chemistry, biology.protein, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa95100df713e2bd6cef9b043c2a9383Test
https://pubmed.ncbi.nlm.nih.gov/31607749Test -
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المؤلفون: Neal Rosen, Yijun Gao, Ann Maria, Huiyong Zhao, Julianne R. Carson, Jorge S. Reis-Filho, Arnaud Da Cruz Paula, Elisa de Stanchina, Britta Weigelt, Na Na, Rona Yaeger, Alexander N. Gorelick, Jaclyn F. Hechtman, Robert A. Lefkowitz, Barry S. Taylor, Zhan Yao
المصدر: Cancer discovery. 9(9)
مصطلحات موضوعية: 0301 basic medicine, Adult, Proto-Oncogene Proteins B-raf, Mutant, Allosteric regulation, MAP Kinase Kinase 1, Article, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, Growth factor receptor, Allosteric Regulation, Cell Line, Tumor, medicine, Panitumumab, Animals, Humans, Protein Kinase Inhibitors, Binding Sites, MEK inhibitor, Binimetinib, Resistance mutation, 030104 developmental biology, Oncology, chemistry, Amino Acid Substitution, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Mutation (genetic algorithm), Colonic Neoplasms, Cancer research, NIH 3T3 Cells, Benzimidazoles, Female, medicine.drug, Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d3553cf0085456723eba27849487ab3Test
https://pubmed.ncbi.nlm.nih.gov/31227518Test -
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المؤلفون: Jeffrey T. Guptill, Janice M. Massey, Shruti M. Raja, Karissa L. Gable, John S. Yi, Jay Shin, Melissa A. Russo, Lisa D. Hobson-Webb, Vern C. Juel
المصدر: Exp Neurol
مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Cell, Retinoic acid, Autoantigens, Article, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Developmental Neuroscience, Myasthenia Gravis, medicine, Humans, Immunologic Factors, Cytotoxic T cell, Receptors, Cholinergic, Interferon gamma, Transcription factor, Aged, Autoantibodies, Acetylcholine receptor, Aged, 80 and over, Interleukin-17, Cell Differentiation, Middle Aged, Nuclear Receptor Subfamily 1, Group F, Member 3, medicine.disease, Myasthenia gravis, 030104 developmental biology, medicine.anatomical_structure, Neurology, chemistry, Cancer research, Th17 Cells, Female, Interleukin 17, 030217 neurology & neurosurgery, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22af72e4b636c454fa4927589939c9c7Test
https://doi.org/10.1016/j.expneurol.2019.113146Test -
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المؤلفون: Larry M. Karnitz, Mrinal M. Patnaik, Scott H. Kaufmann, Ivana Gojo, Jonathan Webster, Lawrence E. Morris, Amanda L. Blackford, Judith E. Karp, L. Austin Doyle, B. Douglas Smith, Lihua Wang, Raoul Tibes, Gary L. Rosner, Robert J. Kinders, Mark R. Litzow, Catherine J. Huntoon
مصطلحات موضوعية: 0301 basic medicine, Adult, Male, Cancer Research, Antineoplastic Agents, Article, 03 medical and health sciences, chemistry.chemical_compound, Refractory, medicine, Humans, CHEK1, Cytotoxicity, Aged, Genetics, business.industry, Cytarabine, Myeloid leukemia, Hematology, Middle Aged, medicine.disease, CHK1 Inhibitor MK-8776, carbohydrates (lipids), Leukemia, Leukemia, Myeloid, Acute, 030104 developmental biology, Pyrimidines, Oncology, chemistry, Drug Resistance, Neoplasm, Checkpoint Kinase 1, Cancer research, Pyrazoles, Female, biological phenomena, cell phenomena, and immunity, Neoplasm Recurrence, Local, business, Cytosine, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f59f0dae29b3c8ae532ad2068ee9e70Test
https://europepmc.org/articles/PMC5639924Test/