نتائج البحث

1

SphK1‐driven autophagy potentiates focal adhesion paxillin‐mediated metastasis in colorectal cancer

المؤلفون: Zhihai Liang, Er-Dan Wei, Li-Ye Zhu, Shi-Quan Liu, Lan Lin, Shibo Luo, Jie-An Huang, Jiangni Wu, Xinze Qiu, Mengbin Qin, Da Chen, Zhenhua Fu

المصدر: Cancer Medicine
Cancer Medicine, Vol 10, Iss 17, Pp 6010-6021 (2021)

مصطلحات موضوعية: Adult, Male, Cancer Research, autophagy, Colorectal cancer, sphingosine kinase 1, Mice, Nude, Vimentin, colorectal cancer, macromolecular substances, environment and public health, Metastasis, Focal adhesion, Mice, medicine, Animals, Humans, Radiology, Nuclear Medicine and imaging, Neoplasm Metastasis, metastases, neoplasms, Paxillin, RC254-282, Research Articles, Cancer Biology, Aged, Aged, 80 and over, paxillin, Focal Adhesions, biology, Chemistry, Autophagy, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Middle Aged, medicine.disease, digestive system diseases, Phosphotransferases (Alcohol Group Acceptor), Oncology, Sphingosine kinase 1, Cancer research, biology.protein, Immunohistochemistry, Female, Colorectal Neoplasms, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b6b2bae84bdf5ef70cc291fbe7798e5Test
http://europepmc.org/articles/PMC8419751Test

2

The RNA‐binding protein SORBS2 suppresses hepatocellular carcinoma tumourigenesis and metastasis by stabilizing RORA mRNA

المؤلفون: Lili Han, Chen Huang, Shuqun Zhang

المصدر: Liver International. 39:2190-2203

مصطلحات موضوعية: Adult, Male, Carcinoma, Hepatocellular, Epithelial-Mesenchymal Transition, Carcinogenesis, Retinoic acid, Mice, Nude, RNA-binding protein, Biology, Flow cytometry, Metastasis, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Western blot, Cell Movement, Cell Line, Tumor, medicine, Animals, Humans, RNA, Messenger, Neoplasm Metastasis, 3' Untranslated Regions, Adaptor Proteins, Signal Transducing, Cell Proliferation, Neoplasm Staging, Messenger RNA, Hepatology, medicine.diagnostic_test, Cell growth, Liver Neoplasms, RNA-Binding Proteins, Nuclear Receptor Subfamily 1, Group F, Member 1, Middle Aged, medicine.disease, Xenograft Model Antitumor Assays, digestive system diseases, Gene Expression Regulation, Neoplastic, Disease Models, Animal, chemistry, 030220 oncology & carcinogenesis, Cancer research, Immunohistochemistry, Female, RNA Interference, 030211 gastroenterology & hepatology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a351c65239393e2bea3aa0c5b912c21Test
https://doi.org/10.1111/liv.14202Test

3

MiR-18a-downregulated RORA inhibits the proliferation and tumorigenesis of glioma using the TNF-α-mediated NF-κB signaling pathway

المؤلفون: Zhitao Jing, Haiying Zhang, Dan Zou, Ye Zhang, Jiangfeng Hu, Dianqi Hou, Jinpeng Zhou, Junshuang Zhao, Long Li, Yang Jiang

المصدر: EBioMedicine
EBioMedicine, Vol 52, Iss, Pp-(2020)

مصطلحات موضوعية: 0301 basic medicine, Male, Research paper, Retinoic acid, lcsh:Medicine, medicine.disease_cause, RORA, chemistry.chemical_compound, Mice, 0302 clinical medicine, 3' Untranslated Regions, microRNA-18a, Orphan receptor, lcsh:R5-920, Cell Cycle, NF-kappa B, Nuclear Receptor Subfamily 1, Group F, Member 1, General Medicine, Glioma, Middle Aged, Prognosis, Immunohistochemistry, Cell Transformation, Neoplastic, 030220 oncology & carcinogenesis, Female, RNA Interference, Signal transduction, lcsh:Medicine (General), Signal Transduction, Adult, Biology, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Neurosphere, Cell Line, Tumor, microRNA, medicine, Biomarkers, Tumor, Glioma stem cells, Animals, Humans, Viability assay, neoplasms, Aged, Tumor Necrosis Factor-alpha, Gene Expression Profiling, lcsh:R, Computational Biology, medicine.disease, nervous system diseases, Disease Models, Animal, MicroRNAs, 030104 developmental biology, chemistry, Tumorigenesis, Cancer research, Carcinogenesis, Biomarkers

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd3380a25215b81edc3a7afc40d2ddbbTest
http://europepmc.org/articles/PMC7016377Test

4

Long non-coding RNA UBE2CP3 enhances HCC cell secretion of VEGFA and promotes angiogenesis by activating ERK1/2/HIF-1α/VEGFA signalling in hepatocellular carcinoma

المؤلفون: Pan Li, Hongwei Liu, Yu Wang, Yan-Wei Hu, Jing Chen, Jiehua Li, Shun-wang Cao, Lei Zheng, Jinduan Lin, Qian Wang, Jumei Liu

المصدر: Journal of Experimental & Clinical Cancer Research, Vol 37, Iss 1, Pp 1-13 (2018)

مصطلحات موضوعية: 0301 basic medicine, CD31, Male, Vascular Endothelial Growth Factor A, Cancer Research, Angiogenesis, Cell, Chick Embryo, Metastasis, Mice, 0302 clinical medicine, Nude mouse, Cell Movement, Neoplasm Metastasis, Tube formation, Mitogen-Activated Protein Kinase 1, Mitogen-Activated Protein Kinase 3, biology, Neovascularization, Pathologic, Chemistry, Liver Neoplasms, Middle Aged, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Immunohistochemistry, Gene Expression Regulation, Neoplastic, Vascular endothelial growth factor A, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, Female, RNA, Long Noncoding, Signal Transduction, Adult, Carcinoma, Hepatocellular, Models, Biological, lcsh:RC254-282, 03 medical and health sciences, Cell Line, Tumor, Long non-coding RNA, UBE2CP3, HCC, Angiogenesis, ERK, VEGFA, Co-culture, medicine, Animals, Humans, Aged, Cell Proliferation, Oncogene, medicine.disease, biology.organism_classification, Hypoxia-Inducible Factor 1, alpha Subunit, digestive system diseases, 030104 developmental biology, Cancer research, Neoplasm Grading

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::423e5b9d8ed6ebd2a1fd4b596a467c77Test
http://link.springer.com/article/10.1186/s13046-018-0727Test-1

5

Cytoplasmic LIF reprograms invasive mode to enhance NPC dissemination through modulating YAP1-FAK/PXN signaling

المؤلفون: Chiou-Hwa Yuh, Shih Sheng Jiang, Chun Nan OuYang, Ngan Ming Tsang, Shu Chen Liu, Tien Hsu, An Ko Chung, Yu-Sun Chang, Ya Ping Liu, Chuen Hsueh

المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, Male, General Physics and Astronomy, Mice, SCID, Leukemia Inhibitory Factor, Metastasis, Mice, Neoplasm Metastasis, lcsh:Science, reproductive and urinary physiology, YAP1, Aged, 80 and over, Multidisciplinary, Nasopharyngeal Carcinoma, Kinase, Chemistry, Signal transducing adaptor protein, Middle Aged, Immunohistochemistry, embryonic structures, Female, hormones, hormone substitutes, and hormone antagonists, Signal Transduction, Adult, endocrine system, Epithelial-Mesenchymal Transition, Receptors, OSM-LIF, Science, Blotting, Western, General Biochemistry, Genetics and Molecular Biology, Article, Focal adhesion, 03 medical and health sciences, Young Adult, medicine, Human Umbilical Vein Endothelial Cells, otorhinolaryngologic diseases, Animals, Humans, Neoplasm Invasiveness, Adaptor Proteins, Signal Transducing, Aged, urogenital system, Cancer, Nasopharyngeal Neoplasms, YAP-Signaling Proteins, General Chemistry, medicine.disease, Phosphoproteins, Xenograft Model Antitumor Assays, stomatognathic diseases, 030104 developmental biology, Nasopharyngeal carcinoma, Focal Adhesion Kinase 1, Cancer research, lcsh:Q, Paxillin, Leukemia inhibitory factor, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de69d2972cda5f8e3890c7fa1222a2d4Test
http://link.springer.com/article/10.1038/s41467-018-07660-6Test

6

Galectin‐1 studies in proliferative diabetic retinopathy

المؤلفون: Mohammad Mairaj Siddiquei, Eef Allegaert, Priscilla W Gikandi, Kaiser Alam, Ahmed M. Abu El-Asrar, Gert De Hertogh, Ajmal Ahmad, Ghislain Opdenakker

المصدر: Acta Ophthalmologica. 98

مصطلحات موضوعية: Adult, Male, CD31, Galectin 1, Angiogenesis, Blotting, Western, Ependymoglial Cells, Enzyme-Linked Immunosorbent Assay, Inflammation, Diabetes Mellitus, Experimental, Rats, Sprague-Dawley, Young Adult, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Downregulation and upregulation, Western blot, Vitrectomy, Neuropilin 1, otorhinolaryngologic diseases, medicine, Animals, Humans, Cells, Cultured, Aged, Aged, 80 and over, Diabetic Retinopathy, medicine.diagnostic_test, Chemistry, General Medicine, Middle Aged, Immunohistochemistry, Molecular biology, Rats, Vitreous Body, Endothelial stem cell, Vascular endothelial growth factor, Ophthalmology, 030221 ophthalmology & optometry, Female, sense organs, medicine.symptom, Biomarkers, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76fe928c6177584b8e96a08b07a714c6Test
https://doi.org/10.1111/aos.14191Test

7

Upregulation of microRNA-7 contributes to inhibition of the growth and metastasis of osteosarcoma cells through the inhibition of IGF1R

المؤلفون: Guojie Wang, Ming Zhao, Zuojun Zhang

المصدر: Journal of cellular physiology. 234(12)

مصطلحات موضوعية: 0301 basic medicine, Adult, Male, Epithelial-Mesenchymal Transition, Adolescent, Physiology, Clinical Biochemistry, Mice, Nude, Apoptosis, Metastasis, Receptor, IGF Type 1, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Downregulation and upregulation, Cell Movement, Cell Line, Tumor, medicine, Animals, Humans, Neoplasm Invasiveness, Neoplasm Metastasis, Child, Insulin-like growth factor 1 receptor, Aged, Cell Proliferation, Osteosarcoma, Osteoblasts, biology, Base Sequence, Chemistry, Cell Cycle, Cell Biology, Methylation, DNA Methylation, Middle Aged, medicine.disease, Proliferating cell nuclear antigen, Up-Regulation, Gene Expression Regulation, Neoplastic, MicroRNAs, 030104 developmental biology, 030220 oncology & carcinogenesis, Cancer research, biology.protein, Immunohistochemistry, Female

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c0a78281044ace9b85bc865be24751dTest
https://pubmed.ncbi.nlm.nih.gov/31102265Test

8

PLCε regulates prostate cancer mitochondrial oxidative metabolism and migration via upregulation of Twist1

المؤلفون: Xiao Wang, Yingying Gao, Chunli Luo, Jinxiao Yang, Lingfang Niu, Luo Li, Xiaohou Wu, Jiaxin Fan, Yanru Fan, Limei Duan

المصدر: Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-16 (2019)
Journal of Experimental & Clinical Cancer Research : CR

مصطلحات موضوعية: Male, 0301 basic medicine, MAPK/ERK pathway, Cancer Research, Cell, medicine.disease_cause, Oxidative Phosphorylation, Small hairpin RNA, Mice, Phosphoinositide Phospholipase C, 0302 clinical medicine, Genes, Reporter, Migration, PLCε, Gene knockdown, Prostate cancer, Chemistry, Kinase, Nuclear Proteins, Middle Aged, Mitochondrial metabolic, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Immunohistochemistry, Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha, Mitochondria, Gene Expression Regulation, Neoplastic, Protein Transport, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, Signal transduction, Twist1, Adult, animal structures, Models, Biological, lcsh:RC254-282, 03 medical and health sciences, Downregulation and upregulation, Cell Line, Tumor, medicine, Animals, Humans, Aged, Neoplasm Staging, Research, Twist-Related Protein 1, Ubiquitination, Prostatic Neoplasms, MAPK, Disease Models, Animal, 030104 developmental biology, Cancer research, Neoplasm Grading, Carcinogenesis

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb99119740612c0ec5c1e4f6572dcdbdTest
https://doi.org/10.1186/s13046-019-1323-8Test

9

Wogonin attenuates nasal polyp formation by inducing eosinophil apoptosis through HIF-1α and survivin suppression

المؤلفون: Yun-Jae Jung, Hyun Woo Shin, Jong Wan Park, Roza Khalmuratova, Mingyu Lee, Ji-Hun Mo

المصدر: Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports

مصطلحات موضوعية: Male, 0301 basic medicine, Survivin, Fluorescent Antibody Technique, Gene Expression, Apoptosis, Leukocyte Count, Mice, chemistry.chemical_compound, 0302 clinical medicine, Eosinophilic, Medicine, Nasal polyps, 030223 otorhinolaryngology, Mice, Inbred BALB C, Multidisciplinary, medicine.diagnostic_test, Caspase 3, Middle Aged, respiratory system, Immunohistochemistry, medicine.anatomical_structure, Flavanones, Airway Remodeling, Cytokines, Female, Protein Binding, Adult, Science, Article, Cell Line, Flow cytometry, 03 medical and health sciences, Nasal Polyps, Wogonin, Animals, Humans, Aged, Inflammation, business.industry, Eosinophil, Hypoxia-Inducible Factor 1, alpha Subunit, medicine.disease, Eosinophils, Disease Models, Animal, 030104 developmental biology, Gene Expression Regulation, chemistry, Cancer research, business, Biomarkers

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f742058280e9d9082d51dfd131286d3Test
https://doaj.org/article/7674a023192b40baa15034b4fa347982Test

10

Along with its favorable prognostic role, CLCA2 inhibits growth and metastasis of nasopharyngeal carcinoma cells via inhibition of FAK/ERK signaling

المؤلفون: Yan Hong Lang, Yun Cao, Wen Wen Wei, Chang-Zhi Li, Li Cao, Yan Mei, Dong Hua Luo, Ying Ying Liang, Ping Xie, Bi Jun Huang, Dong Fang Meng, Rui Sun, Qin Yang, Chao Nan Qian, Hao Hu, Yuan Yuan Qiang, Jun Ping Yang, Li Xia Peng, Liang Xu, Li Sheng Zheng

المصدر: Journal of Experimental & Clinical Cancer Research, Vol 37, Iss 1, Pp 1-14 (2018)
Journal of Experimental & Clinical Cancer Research : CR

مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, Gene Expression, Metastasis, Mice, 0302 clinical medicine, Cell Movement, Neoplasm Metastasis, Extracellular Signal-Regulated MAP Kinases, Prognostics, FAK/ERK, Chemistry, Cell migration, Middle Aged, Prognosis, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Oncology, 030220 oncology & carcinogenesis, Immunohistochemistry, Female, Signal transduction, Signal Transduction, Adult, Epithelial-Mesenchymal Transition, Cell Survival, lcsh:RC254-282, 03 medical and health sciences, Chloride Channels, Cell Line, Tumor, medicine, otorhinolaryngologic diseases, Nasopharyngeal carcinoma, Animals, Humans, Viability assay, Aged, Neoplasm Staging, CLCA2, Research, medicine.disease, Xenograft Model Antitumor Assays, Disease Models, Animal, stomatognathic diseases, 030104 developmental biology, Apoptosis, Cell culture, Focal Adhesion Kinase 1, Cancer research

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bae6a62578a99fcdc7824e89b862d38eTest
http://link.springer.com/article/10.1186/s13046-018-0692-8Test

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