نتائج البحث

1

Effects of Tirzepatide, a Dual GIP and GLP-1 RA, on Lipid and Metabolite Profiles in Subjects With Type 2 Diabetes

المؤلفون: Kenneth D. Roth, Valentina Pirro, Kevin L. Duffin, Jonathan M. Wilson, Yanzhu Lin, Jill A. Willency, Axel Haupt, Paul L. Milligan, Christopher B. Newgard, Giacomo Ruotolo

المصدر: The Journal of Clinical Endocrinology & Metabolism. 107:363-378

مصطلحات موضوعية: Adult, Blood Glucose, Male, medicine.medical_specialty, Injections, Subcutaneous, Recombinant Fusion Proteins, Endocrinology, Diabetes and Metabolism, Metabolite, Clinical Biochemistry, Glucagon-Like Peptides, Gastric Inhibitory Polypeptide, Type 2 diabetes, Placebo, Biochemistry, Glucagon-Like Peptide-1 Receptor, Receptors, Gastrointestinal Hormone, Young Adult, chemistry.chemical_compound, Endocrinology, Insulin resistance, Glucagon-Like Peptide 1, Weight loss, Internal medicine, Diabetes mellitus, Weight Loss, medicine, Humans, Hypoglycemic Agents, Metabolomics, Triglycerides, Aged, Glycemic, Glycated Hemoglobin, business.industry, Biochemistry (medical), Middle Aged, medicine.disease, Immunoglobulin Fc Fragments, Diabetes Mellitus, Type 2, chemistry, Female, Dulaglutide, medicine.symptom, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3140a92fd3671aef505b0ff756594a2cTest
https://doi.org/10.1210/clinem/dgab722Test

2

The Regulatory Effect of MicroRNA-101-3p on Disc Degeneration by the STC1/VEGF/MAPK Pathway

المؤلفون: Yueming Song, Xin He, Xi Yang, Kun Shi, Yong Huang, Juehan Wang, Limin Liu, Ce Zhu, Ganjun Feng, Jingcheng Wang, Leizhen Huang

المصدر: Oxidative Medicine and Cellular Longevity, Vol 2021 (2021)
Oxidative Medicine and Cellular Longevity

وصف الملف: text/xhtml

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b819441873b03d859c1f092c406c12d5Test
https://doi.org/10.1155/2021/1073458Test

3

Demethylation Status of Somatic DNA Extracted From Pituitary Neuroendocrine Tumors Indicates Proliferative Behavior

المؤلفون: Kinga Németh, Lilla Reiniger, Borbála Szabó, Hajnalka Rajnai, Henriett Butz, Lilla Krokker, Katalin Mészáros, Attila Patócs, Sándor Czirják, Ildikó Krencz, Nikolette Szücs, Katalin Karaszi

المصدر: The Journal of Clinical Endocrinology & Metabolism. 105:2015-2026

مصطلحات موضوعية: Adult, DNA (Cytosine-5-)-Methyltransferase 1, Male, medicine.medical_specialty, Adenoma, Proliferation index, Ubiquitin-Protein Ligases, Endocrinology, Diabetes and Metabolism, Clinical Biochemistry, Decitabine, Biochemistry, DNA methyltransferase, Dioxygenases, Epigenesis, Genetic, Young Adult, chemistry.chemical_compound, Endocrinology, Pituitary adenoma, Proto-Oncogene Proteins, Internal medicine, Biomarkers, Tumor, medicine, Humans, Pituitary Neoplasms, Aged, Cell Proliferation, Aged, 80 and over, Biochemistry (medical), Tet methylcytosine dioxygenase 1, DNA, Neoplasm, DNA Methylation, Middle Aged, Prognosis, medicine.disease, Demethylating agent, DNA-Binding Proteins, Neuroendocrine Tumors, chemistry, Case-Control Studies, 5-Methylcytosine, DNMT1, Cancer research, Female, Follow-Up Studies, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::192d75572724e066ef5fcd90b46c5c18Test
https://doi.org/10.1210/clinem/dgaa156Test

4

On the relationship between VDR, RORα and RORγ receptors expression and HIF1‐α levels in human melanomas

المؤلفون: Anton M. Jetten, Andrzej Slominski, Wojciech Jóźwicki, Anna A. Brożyna

المصدر: Exp Dermatol

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Skin Neoplasms, Retinoic acid, Dermatology, Biology, T-Lymphocytes, Regulatory, Biochemistry, Calcitriol receptor, Article, 030207 dermatology & venereal diseases, 03 medical and health sciences, chemistry.chemical_compound, Lymphocytes, Tumor-Infiltrating, 0302 clinical medicine, CYP24A1, medicine, Humans, Single-Blind Method, Lymphocytes, Vitamin D3 24-Hydroxylase, Receptor, Melanoma, Molecular Biology, Aged, 25-Hydroxyvitamin D3 1-alpha-Hydroxylase, Aged, 80 and over, Cell Nucleus, Orphan receptor, FOXP3, Nuclear Receptor Subfamily 1, Group F, Member 1, Middle Aged, Nuclear Receptor Subfamily 1, Group F, Member 3, Hypoxia-Inducible Factor 1, alpha Subunit, medicine.disease, Cell Hypoxia, Neoplasm Proteins, Gene Expression Regulation, Neoplastic, 030104 developmental biology, chemistry, Nuclear receptor, Cancer research, Receptors, Calcitriol, Female

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3aa44913d2ff840a9108510f572a732Test
https://doi.org/10.1111/exd.14002Test

5

ABCA1- and ABCG1-mediated cholesterol efflux capacity of cerebrospinal fluid is impaired in Alzheimer's disease

المؤلفون: Franco Bernini, Maria Pia Adorni, Francesca Zimetti, Daniela Galimberti, Paolo Caffarra, Cinzia Marchi, Marco Spallazzi, Nicoletta Ronda, Federica Barocco

المصدر: Journal of Lipid Research, Vol 60, Iss 8, Pp 1449-1456 (2019)
J Lipid Res

مصطلحات موضوعية: 0301 basic medicine, Apolipoprotein E, Adult, Male, medicine.medical_specialty, apolipoprotein A-I, QD415-436, 030204 cardiovascular system & hematology, Biochemistry, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Endocrinology, Cerebrospinal fluid, Alzheimer Disease, Internal medicine, medicine, Dementia, Humans, ATP Binding Cassette Transporter, Subfamily G, Member 1, Aged, apolipoprotein E, ATP-binding cassette A1, Amyloid beta-Peptides, biology, Cholesterol, business.industry, Neurodegeneration, ATP-binding cassette G1, Cell Biology, Middle Aged, apolipoprotein E4, medicine.disease, Pathophysiology, Peptide Fragments, 030104 developmental biology, chemistry, ABCA1, biology.protein, cardiovascular system, Female, lipids (amino acids, peptides, and proteins), Efflux, business, Patient-Oriented and Epidemiological Research, apolipoproteins, ATP Binding Cassette Transporter 1

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c32af647e6d95ae13ea957fc028bbe95Test
http://www.sciencedirect.com/science/article/pii/S0022227520322392Test

6

Bariatric Surgery: It’s Not Just Incretins!

المؤلفون: Rafael Ferraz-Bannitz, Sangeeta R. Kashyap, Mary-Elizabeth Patti

المصدر: The Journal of Clinical Endocrinology and Metabolism

مصطلحات موضوعية: Adult, Blood Glucose, Male, medicine.medical_specialty, Roux-en-Y gastric bypass, Endocrinology, Diabetes and Metabolism, Clinical Biochemistry, Gastric Bypass, Type 2 diabetes, Infusions, Subcutaneous, Biochemistry, Gastrointestinal Hormones, Young Adult, chemistry.chemical_compound, Endocrinology, Glucagon-Like Peptide 1, Commentaries, Internal medicine, Weight Loss, peptide YY, medicine, Humans, Metabolomics, Single-Blind Method, Online Only Articles, Aged, Caloric Restriction, business.industry, Biochemistry (medical), Middle Aged, medicine.disease, Obesity, Morbid, Oxyntomodulin, Treatment Outcome, glucagon-like peptide-1, Diabetes Mellitus, Type 2, chemistry, Peptide YY, Drug Therapy, Combination, Female, type 2 diabetes, business, AcademicSubjects/MED00250

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::357fbf783be968d86296325555150f68Test
https://doi.org/10.1210/clinem/dgab694Test

7

Reverse Phase Protein Array Reveals Correlation of Retinoic Acid Metabolism With Cardiomyopathy in Friedreich's Ataxia

المؤلفون: Lauren A. Hauser, Marek Napierala, Amanda Clark, Jennifer M. Farmer, Kimal Rajapakshe, David A. Lynch, Peining Xu, Clementina Mesaros, Dean P. Edwards, Yu-Yun Chen, Ian A. Blair, Shixia Huang, Cristian Coarfa, Jill S. Napierala

المصدر: Molecular & Cellular Proteomics : MCP

مصطلحات موضوعية: Male, Proteomics, Retinoic acid, Biochemistry, Analytical Chemistry, chemistry.chemical_compound, reverse phase protein array, Iron-Binding Proteins, Gene expression, RA, retinoic acid, Cells, Cultured, ROL, retinol, 0303 health sciences, frataxin, biology, LDH, lactate dehydrogenase, 030302 biochemistry & molecular biology, PDT, population doubling time, Reverse phase protein lysate microarray, Middle Aged, DE, differentially expressed, Aldehyde Oxidoreductases, H2O2, hydrogen peroxide, CTRL, control, Biomarker (medicine), biomarker, Female, medicine.symptom, Cardiomyopathies, Adult, IRB, Institutional Review Board, Ataxia, Adolescent, retinoid metabolism, ALDH1A3, aldehyde dehydrogenase family 1 member A3, Protein Array Analysis, UAB, University of Alabama at Birmingham, GAA, guanine–adenine–adenine, CHOP, Children's Hospital of Philadelphia, 03 medical and health sciences, Retinoids, Young Adult, FRDA, Friedreich's ataxia, medicine, Humans, RAL, retinal, Molecular Biology, 030304 developmental biology, AOX1, aldehyde oxidase 1, Aged, RPPA, reverse phase protein array, HL, hearing loss, Research, Friedreich's ataxia, FARS, Functional Assessment Rating Scale, FC, fold change, Fibroblasts, Molecular biology, Fold change, CMP, cardiomyopathy, FXN, frataxin, chemistry, ISTD, internal standard, Friedreich Ataxia, BCM, Baylor College of Medicine, Frataxin, biology.protein, integrins, Biomarkers

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::239d5431dbcbfd7df7c1a470624aee8dTest
http://europepmc.org/articles/PMC8214145Test

8

Targeting aberrant DNA hypermethylation as a driver of ATL leukemogenesis by using the new oral demethylating agent OR-2100

المؤلفون: Satoshi Yamashita, Naoko Hattori, Yuki Kurahashi, Toshikazu Ushijima, Naoko Sueoka-Aragane, Tatsuro Watanabe, Akemi Sato, Kensuke Kojima, Hideaki Nakamura, Atsushi Kawaguchi, Shinya Kimura, Eisaburo Sueoka, Nao Yoshida, Kazuharu Kamachi, Seiji Okada, Hiroshi Ureshino, Yuki Fukuda-Kurahashi

المصدر: Blood. 136:871-884

مصطلحات موضوعية: Adult, 0301 basic medicine, Pyridines, viruses, Immunology, Administration, Oral, Decitabine, Antineoplastic Agents, Biology, Biochemistry, Mice, Young Adult, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, immune system diseases, hemic and lymphatic diseases, medicine, Animals, Humans, Leukemia-Lymphoma, Adult T-Cell, Molecular Targeted Therapy, Cells, Cultured, Aged, Mice, Knockout, Regulation of gene expression, Human T-lymphotropic virus 1, Mice, Inbred BALB C, Gene Expression Regulation, Leukemic, Cell growth, T-cell receptor, Drugs, Investigational, Cell Biology, Hematology, DNA Methylation, Cell Transformation, Viral, HTLV-I Infections, Xenograft Model Antitumor Assays, Demethylation, Demethylating agent, 030104 developmental biology, chemistry, Cell culture, 030220 oncology & carcinogenesis, DNA methylation, Cancer research, Female, medicine.drug, DNA hypomethylation

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30f0e7224c117c25f69a987a740a43e5Test
https://doi.org/10.1182/blood.2019003084Test

9

A randomized double-blind trial of 3 aspirin regimens to optimize antiplatelet therapy in essential thrombocythemia

المصدر: Blood. 136:171-182

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2745a074f0e9fb3a40b7e799bc767c0Test
https://doi.org/10.1182/blood.2019004596Test

10

Cardiovascular Biomarkers and Calculated Cardiovascular Risk in Orally Treated Type 2 Diabetes Patients: Is There a Link?

المؤلفون: Mihail Boyanov, Adelina Tsakova, Deniz Bakalov, Atanas Kundurdjiev, Aleksandra Markova

المصدر: Hormone and Metabolic Research. 53:41-48

مصطلحات موضوعية: Adult, Male, Placental growth factor, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, Cardiovascular biomarkers, Clinical Biochemistry, Administration, Oral, 030209 endocrinology & metabolism, Type 2 diabetes, 030204 cardiovascular system & hematology, Risk Assessment, Biochemistry, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Endocrinology, Risk Factors, Internal medicine, medicine, Humans, Stroke, Aged, Glycemic, Aged, 80 and over, Framingham Risk Score, business.industry, Biochemistry (medical), Endothelial Cells, General Medicine, Middle Aged, medicine.disease, Endothelin 1, Diabetes Mellitus, Type 2, chemistry, Cardiovascular Diseases, Cardiology, Regression Analysis, Female, Asymmetric dimethylarginine, business, Biomarkers

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::583ea9e316594bf4d15dd4fc5e7a1917Test
https://doi.org/10.1055/a-1199-2378Test

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