دورية أكاديمية

Can oxymetazoline simulate the outcomes of septoplasty and inferior turbinate reduction surgery?

التفاصيل البيبلوغرافية
العنوان: Can oxymetazoline simulate the outcomes of septoplasty and inferior turbinate reduction surgery?
المؤلفون: Lepley, Thomas J.1 (AUTHOR), Wu, Zhenxing1 (AUTHOR), Root, Zachary T.1 (AUTHOR), Spector, Barak M.1 (AUTHOR), Chapman, Robbie J.1 (AUTHOR), Schneller, Aspen R.1 (AUTHOR), Kelly, Kathleen1 (AUTHOR), Otto, Bradley A.1 (AUTHOR), Zhao, Kai1 (AUTHOR) zhao.1949@osu.edu
المصدر: International Forum of Allergy & Rhinology. May2023, Vol. 13 Issue 5, p961-963. 3p.
مصطلحات موضوعية: *NASAL surgery, *CONE beam computed tomography, *ADRENERGIC agonists, *COMPUTATIONAL fluid dynamics
مستخلص: Keywords: adrenergic receptor agonist; computational fluid dynamics; nasal decongestion; nasal obstruction; surgical outcome; vasoconstriction EN adrenergic receptor agonist computational fluid dynamics nasal decongestion nasal obstruction surgical outcome vasoconstriction 961 963 3 04/25/23 20230501 NES 230501 INTRODUCTION Inferior turbinate hypertrophy (ITH), with or without nasal septum deviation, is among the most common surgically correctable etiologies of nasal obstruction.[1] The current challenge associated with surgical decision is twofold: 1) there are significant variabilities in individual nasal anamtomies as well as in surgical techniques; 2) there are few objective measures to identify which patients would benefit from surgery.[[2]] A patient's responsiveness to oxymetazoline has been often used as a proxy for surgical candidacy.[3] Oxymetazoline is a selective 1 adrenergic receptor agonist and 2 adrenergic receptor partial agonist, which causes vasoconstriction and results in nasal decongestion since the soft tissue of the turbinates is rich in venous sinusoids and seromucinous glands. The patient completed the NOSE, SNOT-22, and Visual Analog Scales (VAS) for nasal obstruction (0: completely clear, 10: completely obstructed) immediately before his baseline computed tomography (CT) scan. [Extracted from the article]
قاعدة البيانات: Academic Search Index
الوصف
تدمد:20426976
DOI:10.1002/alr.23094