دورية أكاديمية
Risk factors for the development of metabolic syndrome in obese children and adolescents
| العنوان: | Risk factors for the development of metabolic syndrome in obese children and adolescents |
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| المؤلفون: | Folić Nevena, Folić Marko, Marković Slavica, Anđelković Marija, Janković Slobodan |
| المصدر: | Srpski Arhiv za Celokupno Lekarstvo, Vol 143, Iss 3-4, Pp 146-152 (2015) |
| بيانات النشر: | Serbian Medical Society, 2015. |
| سنة النشر: | 2015 |
| المجموعة: | LCC:Medicine |
| مصطلحات موضوعية: | metabolic syndrome, child obesity, adolescent obesity, risk factors, Medicine |
| الوصف: | Introduction. High prevalence of metabolic syndrome (MetS) in children and adolescents is a great concern of the modern society. Objective. Our aim was to determine the influence of previously investigated, but also and potentially novel risk factors for the development of metabolic syndrome in children and adolescents. Methods. Observational case-control clinical study was conducted involving children and adolescents with obesity/metabolic syndrome, treated on inpatient basis from January 2008 to January 2012 at the Pediatric Clinic of the Clinical Centre Kragujevac, Kragujevac, Serbia. The group of “cases” (n=28) included patients aged 10-16 years with the diagnosis of metabolic syndrome according to the International Diabetes Federation (IDF) criteria, while the control group included twice as many obese patients (n=56) matched to the compared group. Results. Presence of maternal gestational diabetes (ORadjusted: 39.426; 95% CI: 1.822-853.271; p=0.019), and/or lack of breastfeeding in the first six months of life (ORadjusted: 0.079; 95% CI: 0.009-0.716; p=0.024) were significant predictors for developing MetS. Also, microalbuminuria is associated with MetS in obese children and adolescents (ORadjusted: 1.686; 95% CI: 1.188-2.393; p=0.003). Conclusion. Presence of maternal gestational diabetes and/or lack of infant breastfeeding are considered as relevant factors that may contribute to the increased risk of developing MetS syndrome, while microalbuminuria is frequently associated with MetS in obese children and adolescents. [Projekat Ministarstva nauke Republike Srbije, br. 175007] |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English Serbian |
| تدمد: | 0370-8179 |
| العلاقة: | https://doaj.org/toc/0370-8179Test |
| DOI: | 10.2298/SARH1504146F |
| الوصول الحر: | https://doaj.org/article/d292d6c2a3a2449c85168353144b77fcTest |
| رقم الانضمام: | edsdoj.292d6c2a3a2449c85168353144b77fc |
| قاعدة البيانات: | Directory of Open Access Journals |
| تدمد: | 03708179 |
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| DOI: | 10.2298/SARH1504146F |