دورية أكاديمية
The COVID-19 Pandemic Affects Seasonality, With Increasing Cases of New-Onset Type 1 Diabetes in Children, From the Worldwide SWEET Registry
| العنوان: | The COVID-19 Pandemic Affects Seasonality, With Increasing Cases of New-Onset Type 1 Diabetes in Children, From the Worldwide SWEET Registry |
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| المؤلفون: | Reschke, F, Lanzinger, S, Herczeg, V, Prahalad, P, Schiaffini, R, Mul, D, Clapin, H, Zabeen, B, Pelicand, J, Phillip, M, Limbert, C, Danne, T, Alonso, GT, Rhodes, ET, Davis, E, Veeze, HJ, Maahs, D, Cardona-Hernandez, R, Sumnik, Z, Corathers, S, Bratina, N, Gevers, E, Imane, Z, Piccini, B, Forsander, G, Pacaud, D, Maffeis, C, Campbell, F, Bonfanti, R, de Sanctis, L, Krone, RE, Toth-Heyn, P, Witsch, M, Arsanoglu, I, Jefferies, C, Landry, A, Beltrand, J, Amed, S, Rami-Merhar, B, Barat, P, Szypowska, A, Casteels, K, Savova, R, Cherubini, V, de Bock, M, Todorovic, S, Moravej, H, Pozgaj Sepac, M, Mazur, A, Gerasimidou-Vazeou, A, Iotova, V, O’Riordan, S, Chobot, A, Herbst, A, Ngwu, U, Cody, D, Birkebæk, NH, Hanas, R, Goksen, D, Sarda, A, Chobot, J, Mirante, A, Richmond Padilla, E, Tsiroukidou, K, Saboo, B, Kanaka-Gantenbein, C, Foskett, D, Jali, S, Verkauskiene, R, Castro-Correia, C, Kumar Guness, P, Cotterill, A, Kumari Mohan, M, Spehar Uroic, A, Goss, P, Svensson, J, Ramchandani, GD, Coutant, R, Mantilla, L, Sima, A, Hyun Kim, J, Galli-Tsinopoulou, A, Ribeiro, R, O’Gorman, C, Fonna, H, Bratke, H, El Habashy, S, Gokalani, R, Scharf Pinto, M, Chavda, V |
| بيانات النشر: | American Diabetes Association |
| سنة النشر: | 2022 |
| المجموعة: | Repositório do Centro Hospitalar de Lisboa Central EPE |
| مصطلحات موضوعية: | Adolescent, COVID-19, Child, Communicable Disease Control, Pandemics, Diabetes Mellitus, Type 1* / epidemiology, Glycated Hemoglobin, Registries, HDE END PED |
| الوصف: | Objective: To analyze whether the coronavirus disease 2019 (COVID-19) pandemic increased the number of cases or impacted seasonality of new-onset type 1 diabetes (T1D) in large pediatric diabetes centers globally. Research design and methods: We analyzed data on 17,280 cases of T1D diagnosed during 2018-2021 from 92 worldwide centers participating in the SWEET registry using hierarchic linear regression models. Results: The average number of new-onset T1D cases per center adjusted for the total number of patients treated at the center per year and stratified by age-groups increased from 11.2 (95% CI 10.1-12.2) in 2018 to 21.7 (20.6-22.8) in 2021 for the youngest age-group, <6 years; from 13.1 (12.2-14.0) in 2018 to 26.7 (25.7-27.7) in 2021 for children ages 6 to <12 years; and from 12.2 (11.5-12.9) to 24.7 (24.0-25.5) for adolescents ages 12-18 years (all P < 0.001). These increases remained within the expected increase with the 95% CI of the regression line. However, in Europe and North America following the lockdown early in 2020, the typical seasonality of more cases during winter season was delayed, with a peak during the summer and autumn months. While the seasonal pattern in Europe returned to prepandemic times in 2021, this was not the case in North America. Compared with 2018-2019 (HbA1c 7.7%), higher average HbA1c levels (2020, 8.1%; 2021, 8.6%; P < 0.001) were present within the first year of T1D during the pandemic. Conclusions: The slope of the rise in pediatric new-onset T1D in SWEET centers remained unchanged during the COVID-19 pandemic, but a change in the seasonality at onset became apparent. ; info:eu-repo/semantics/publishedVersion |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | Diabetes Care . 2022 Nov 1;45(11):2594-2601; http://hdl.handle.net/10400.17/4770Test |
| DOI: | 10.2337/dc22-0278 |
| الإتاحة: | https://doi.org/10.2337/dc22-0278Test http://hdl.handle.net/10400.17/4770Test |
| حقوق: | openAccess |
| رقم الانضمام: | edsbas.9DD1E71C |
| قاعدة البيانات: | BASE |
| DOI: | 10.2337/dc22-0278 |
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