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المؤلفون: Timothy M. Gomez, Massimo M. Onesto, Jennifer Glass, Alec J. McCann, Timothy S. Catlett, Sarah K. Rempel, David Neal Franz
المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
مصطلحات موضوعية: Male, 0301 basic medicine, RHOA, Biopsy, General Physics and Astronomy, Haploinsufficiency, Tuberous sclerosis, Epilepsy, 0302 clinical medicine, Tuberous Sclerosis, Fluorescence Resonance Energy Transfer, Cytoskeleton, Induced pluripotent stem cell, Neurons, Multidisciplinary, TOR Serine-Threonine Kinases, Axon Guidance, Organoids, Ephrins, Signal Transduction, Heterozygote, congenital, hereditary, and neonatal diseases and abnormalities, Adolescent, Neurogenesis, Science, Induced Pluripotent Stem Cells, Myosins, Biology, General Biochemistry, Genetics and Molecular Biology, Cell Line, 03 medical and health sciences, Tuberous Sclerosis Complex 2 Protein, medicine, Humans, Growth cone, neoplasms, General Chemistry, medicine.disease, nervous system diseases, 030104 developmental biology, nervous system, Protein Biosynthesis, biology.protein, Axon guidance, CRISPR-Cas Systems, Nerve Net, TSC2, rhoA GTP-Binding Protein, Neuroscience, 030217 neurology & neurosurgery
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4437dba0e9c068c931e6e9c54481d7bcTest
https://doi.org/10.1038/s41467-021-22770-4Test -
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المؤلفون: David Neal Franz, Bin Zhang, Leah A Gilligan, Darcy A. Krueger, Alexander J. Towbin, Andrew T. Trout, Caroline Raab
المصدر: Radiol Imaging Cancer
مصطلحات موضوعية: Male, Longitudinal study, Pathology, medicine.medical_specialty, Adolescent, Muscle mass, Cross-sectional imaging, Tuberous sclerosis, Text mining, Tuberous Sclerosis, Medicine, Humans, In patient, Longitudinal Studies, Child, PI3K/AKT/mTOR pathway, Psoas Muscles, Retrospective Studies, Original Research, business.industry, TOR Serine-Threonine Kinases, food and beverages, General Medicine, Discovery and development of mTOR inhibitors, medicine.disease, Magnetic Resonance Imaging, Female, business, Tomography, X-Ray Computed
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4103fbf56c2f274ddc4fe7e359668a4aTest
https://pubmed.ncbi.nlm.nih.gov/33778734Test -
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المؤلفون: David Neal Franz, Karen Agricola, Cynthia Tudor, Daniel Ebrahimi-Fakhari, Darcy A. Krueger
المصدر: Pediatric neurology. 105
مصطلحات موضوعية: Adult, Male, Adolescent, Pharmacology, 03 medical and health sciences, Tuberous sclerosis, Young Adult, 0302 clinical medicine, Developmental Neuroscience, Tuberous Sclerosis, 030225 pediatrics, medicine, Cannabidiol, Humans, Drug Interactions, Everolimus, Adverse effect, Child, Mechanistic target of rapamycin, Protein Kinase Inhibitors, Sirolimus, biology, business.industry, TOR Serine-Threonine Kinases, Middle Aged, medicine.disease, Neurology, Child, Preschool, Pediatrics, Perinatology and Child Health, Toxicity, Lymphangioleiomyomatosis, biology.protein, Anticonvulsants, Drug Therapy, Combination, Female, Neurology (clinical), business, 030217 neurology & neurosurgery, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dbb2387e40b9232f862c00834a7dcacTest
https://pubmed.ncbi.nlm.nih.gov/31924480Test -
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المؤلفون: Neva Coello, Maurizio Voi, Kai Grosch, David Neal Franz, Christian Brandt, Zuhal Yapici, John A. Lawson, Jacqueline A. French, Michael Kohrman, Michael Wong, Wing Cheung, Adelheid Wiemer-Kruel, Mathieu Milh
المصدر: Epilepsia
مصطلحات موضوعية: Oncology, Adult, Male, medicine.medical_specialty, Time Factors, Adolescent, TDM, 03 medical and health sciences, Cmin, Young Adult, 0302 clinical medicine, Double-Blind Method, Seizures, Tuberous Sclerosis, Internal medicine, Linear regression, medicine, Humans, Dosing, Everolimus, Adverse effect, Child, TSC, medicine.diagnostic_test, Dose-Response Relationship, Drug, Proportional hazards model, business.industry, dose, Age Factors, Cytochrome P-450 CYP3A Inducers, Middle Aged, refractory, Neurology, Therapeutic drug monitoring, 030220 oncology & carcinogenesis, Concomitant, Child, Preschool, Full‐length Original Research, Female, Neurology (clinical), Drug Monitoring, business, 030217 neurology & neurosurgery, Immunosuppressive Agents, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e85269570c88949365f781d57c01f2b7Test
http://europepmc.org/articles/PMC6033043Test -
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المؤلفون: Steven Sparagana, Antonia Ridolfi, Noah Berkowitz, John J. Bissler, Elena Belousova, David Neal Franz, E. Martina Bebin, Michael Frost, J. Christopher Kingswood
المصدر: Pediatric Nephrology (Berlin, Germany)
مصطلحات موضوعية: Nephrology, Male, medicine.medical_specialty, Pathology, Angiomyolipoma, Adolescent, 030232 urology & nephrology, Urology, Antineoplastic Agents, Astrocytoma, Placebo, Kidney, Pediatrics, 03 medical and health sciences, Tuberous sclerosis, 0302 clinical medicine, Double-Blind Method, Tuberous Sclerosis, Internal medicine, medicine, Humans, 030212 general & internal medicine, Everolimus, Child, Subependymal giant cell astrocytoma, business.industry, medicine.disease, Kidney Neoplasms, medicine.anatomical_structure, Treatment Outcome, Tolerability, Tuberous sclerosis complex, Child, Preschool, Pediatrics, Perinatology and Child Health, Original Article, Female, business, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5169c5cf36e75266af26de4453827911Test
http://europepmc.org/articles/PMC5700234Test -
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المؤلفون: Noah Berkowitz, Petrus J. de Vries, David Neal Franz, Zuhal Yapici, John A. Lawson, Rima Nabbout, Dennis J. Dlugos, Maurizio Voi, Severine Peyrard, Paolo Curatolo, Hiroko Ikeda, Diana Pelov, Tilman Polster, Jacqueline A. French
المصدر: The Lancet. 388:2153-2163
مصطلحات موضوعية: Adult, Male, 0301 basic medicine, medicine.medical_specialty, Adolescent, Placebo-controlled study, Antineoplastic Agents, Placebo, law.invention, 03 medical and health sciences, Tuberous sclerosis, 0302 clinical medicine, Double-Blind Method, Randomized controlled trial, Seizures, Tuberous Sclerosis, law, Internal medicine, Humans, Medicine, Combined Modality Therapy, Everolimus, Child, Aged, Medicine(all), Dose-Response Relationship, Drug, business.industry, General Medicine, Middle Aged, medicine.disease, Settore MED/39 - Neuropsichiatria Infantile, Surgery, Clinical trial, 030104 developmental biology, Child, Preschool, Concomitant, Anticonvulsants, Female, business, 030217 neurology & neurosurgery, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a4c6c454633f380d955764e6ceac4e1Test
https://doi.org/10.1016/s0140-6736Test(16)31419-2 -
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المؤلفون: Nishant Gupta, Weiji Su, David Neal Franz, Francis X. McCormack, Sara Mary Zak, Maxwell Mays, Rhonda D. Szczesniak, Nadine Mokhallati, Darcy A. Krueger
المصدر: Annals of the American Thoracic Society. 16(4)
مصطلحات موضوعية: Pulmonary and Respiratory Medicine, Adult, Male, medicine.medical_specialty, Lung Neoplasms, Adolescent, Tuberous sclerosis, Young Adult, Sex Factors, Tuberous Sclerosis, Internal medicine, Medicine, Humans, In patient, Lymphangioleiomyomatosis, Letters, Survival analysis, Aged, Ohio, Aged, 80 and over, Chi-Square Distribution, business.industry, Middle Aged, medicine.disease, Survival Analysis, Female, business, Chi-squared distribution
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a59e9d4adf5e916e70db4bfe19a3071bTest
https://pubmed.ncbi.nlm.nih.gov/30571922Test -
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المؤلفون: Benoit Scherrer, Kush Kapur, Anna K. Prohl, Darcy A. Krueger, Mustafa Sahin, David Neal Franz, Sean Clancy, Jurriaan M. Peters, Sanjay P. Prabhu, Audrey R. Nath, Simon K. Warfield
المصدر: Pediatric neurology. 90
مصطلحات موضوعية: Male, Adolescent, Antineoplastic Agents, Neuroimaging, Astrocytoma, Article, White matter, 03 medical and health sciences, Tuberous sclerosis, Young Adult, 0302 clinical medicine, Developmental Neuroscience, Tuberous Sclerosis, 030225 pediatrics, medicine, Humans, Everolimus, Longitudinal Studies, Child, Mechanistic target of rapamycin, PI3K/AKT/mTOR pathway, biology, Subependymal giant cell astrocytoma, business.industry, Brain Neoplasms, Radial diffusivity, medicine.disease, White Matter, medicine.anatomical_structure, Diffusion Tensor Imaging, Treatment Outcome, Neurology, Child, Preschool, Pediatrics, Perinatology and Child Health, biology.protein, Female, Neurology (clinical), Nuclear medicine, business, 030217 neurology & neurosurgery, medicine.drug, Diffusion MRI
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fbbea3b4dbb3081f5cd92feeccd4d1fTest
https://pubmed.ncbi.nlm.nih.gov/30424962Test -
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المؤلفون: David Neal Franz, Karen Agricola, Darcy A. Krueger, Severine Peyrard, Katherine Holland‐Bouley, Maxwell Mays, Noah Berkowitz, Cindy Tudor, Sara Miao, Marguerite M. Care
المصدر: Annals of Neurology
مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Adolescent, Urology, Phases of clinical research, Antineoplastic Agents, Astrocytoma, Young Adult, Tuberous sclerosis, Tuberous Sclerosis, Outcome Assessment, Health Care, Humans, Medicine, Everolimus, Child, Adverse effect, Research Articles, Subependymal giant cell astrocytoma, Brain Neoplasms, business.industry, medicine.disease, Surgery, Clinical trial, Upper respiratory tract infection, Neurology, Child, Preschool, Female, Neurology (clinical), business, Research Article, Follow-Up Studies, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beb3fdf3123f7798ba640fb68bfe57e6Test
https://doi.org/10.1002/ana.24523Test -
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المؤلفون: Diana Pelov, Jenna Fan, Hiroko Ikeda, David Neal Franz, Zuhal Yapici, John A. Lawson, Rima Nabbout, Dennis J. Dlugos, Maurizio Voi, Antonia Ridolfi, Petrus J. de Vries, Paolo Curatolo, Jacqueline A. French, Tilman Polster
المصدر: The Lancet. Childadolescent health. 2(7)
مصطلحات موضوعية: 0301 basic medicine, Male, medicine.medical_specialty, Drug Resistant Epilepsy, Adolescent, Phases of clinical research, law.invention, 03 medical and health sciences, Tuberous sclerosis, Epilepsy, 0302 clinical medicine, Randomized controlled trial, Double-Blind Method, law, Tuberous Sclerosis, Internal medicine, Post-hoc analysis, Developmental and Educational Psychology, medicine, Humans, Everolimus, Prospective Studies, Prospective cohort study, Adverse effect, Child, business.industry, medicine.disease, Settore MED/39 - Neuropsichiatria Infantile, 030104 developmental biology, Child, Preschool, Pediatrics, Perinatology and Child Health, Female, business, 030217 neurology & neurosurgery, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f13bc3194bc3191c6f62aa78fe32092Test
https://pubmed.ncbi.nlm.nih.gov/30169310Test