المؤلفون: Roshandel, Delnaz, Chen, Zhuo, Canty, Angelo J, Bull, Shelley B, Natarajan, Rama, Paterson, Andrew D

المصدر: Clinical Epigenetics. 12(1)

مصطلحات موضوعية: Prevention, Autoimmune Disease, Diabetes, Neurosciences, Peripheral Neuropathy, Cardiovascular, Heart Disease, Metabolic and endocrine, Good Health and Well Being, Adolescent, Adult, Albumins, CpG Islands, DNA Methylation, Diabetes Mellitus, Type 1, Diabetic Neuropathies, Epigenesis, Genetic, Female, Genome-Wide Association Study, Humans, Male, Oligonucleotide Array Sequence Analysis, Young Adult, DNA methylation age, Type 1 diabetes, Diabetic complications, DCCT/EDIC Research Group, Genetics, Clinical Sciences, Paediatrics and Reproductive Medicine

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/5k95n6skTest

المؤلفون: Abdelsamed, Hossam A, Zebley, Caitlin C, Nguyen, Hai, Rutishauser, Rachel L, Fan, Yiping, Ghoneim, Hazem E, Crawford, Jeremy Chase, Alfei, Francesca, Alli, Shanta, Ribeiro, Susan Pereira, Castellaw, Ashley H, McGargill, Maureen A, Jin, Hongjian, Boi, Shannon K, Speake, Cate, Serti, Elisavet, Turka, Laurence A, Busch, Michael E, Stone, Mars, Deeks, Steven G, Sekaly, Rafick-Pierre, Zehn, Dietmar, James, Eddie A, Nepom, Gerald T, Youngblood, Ben

المصدر: Nature Immunology. 21(5)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Immunology, Genetics, Diabetes, Autoimmune Disease, Stem Cell Research, Aetiology, 2.1 Biological and endogenous factors, Metabolic and endocrine, Adolescent, Adult, Animals, Autoantigens, CD8-Positive T-Lymphocytes, Cell Plasticity, Cells, Cultured, DNA Methylation, Diabetes Mellitus, Type 1, Epigenesis, Genetic, Female, Flow Cytometry, Humans, Immunologic Memory, Insulin-Secreting Cells, Male, Mice, Pluripotent Stem Cells, Single-Cell Analysis, Young Adult, Biochemistry and cell biology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/26g354xkTest
https://escholarship.org/content/qt26g354xk/qt26g354xk.pdfTest

المؤلفون: Chen, Zhuo, Miao, Feng, Paterson, Andrew D, Lachin, John M, Zhang, Lingxiao, Schones, Dustin E, Wu, Xiwei, Wang, Jinhui, Tompkins, Joshua D, Genuth, Saul, Braffett, Barbara H, Riggs, Arthur D, Natarajan, Rama, Nathan, DM, Zinman, B, Crofford, O, Genuth, S, Brown-Friday, J, Crandall, J, Engel, H, Engel, S, Martinez, H, Phillips, M, Reid, M, Shamoon, H, Sheindlin, J, Gubitosi-Klug, R, Mayer, L, Pendegast, S, Zegarra, H, Miller, D, Singerman, L, Smith-Brewer, S, Novak, M, Quin, J, Palmert, M, Brown, E, McConnell, J, Pugsley, P, Crawford, P, Dahms, W, Brillon, D, Lackaye, ME, Kiss, S, Chan, R, Orlin, A, Rubin, M, Reppucci, V, Lee, T, Heinemann, M, Chang, S, Levy, B, Jovanovic, L, Richardson, M, Bosco, B, Dwoskin, A, Hanna, R, Barron, S, Campbell, R, Bhan, A, Kruger, D, Jones, JK, Edwards, PA, Carey, JD, Angus, E, Thomas, A, Galprin, A, McLellan, M, Whitehouse, F, Bergenstal, R, Johnson, M, Gunyou, K, Thomas, L, Laechelt, J, Hollander, P, Spencer, M, Kendall, D, Cuddihy, R, Callahan, P, List, S, Gott, J, Rude, N, Olson, B, Franz, M, Castle, G, Birk, R, Nelson, J, Freking, D, Gill, L, Mestrezat, W, Etzwiler, D, Morgan, K, Aiello, LP, Golden, E, Arrigg, P, Asuquo, V, Beaser, R, Bestourous, L

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 113(21)

مصطلحات موضوعية: Biological Sciences, Biomedical and Clinical Sciences, Genetics, Nutrition, Human Genome, Diabetes, Prevention, Aetiology, 2.1 Biological and endogenous factors, Metabolic and endocrine, Adolescent, Adult, Carrier Proteins, Cell Line, Tumor, Cohort Studies, DNA Methylation, Diabetes Mellitus, Type 1, Epigenomics, Female, Genetic Loci, Glycated Hemoglobin, Humans, Male, DCCT/EDIC Research Group, DNA methylation, TXNIP, diabetic complications, epigenetics, metabolic memory

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/27c8j3jwTest

المؤلفون: Fan, Yiping, Ghoneim, Hazem, Crawford, Jeremy, Alfei, Francesca, Alli, Shanta, Ribeiro, Susan, Castellaw, Ashley, McGargill, Maureen, Jin, Hongjian, Boi, Shannon, Speake, Cate, Serti, Elisavet, Turka, Laurence, Busch, Michael, Stone, Mars, Abdelsamed, Hossam, Zebley, Caitlin, Nguyen, Hai, Sekaly, Rafick-Pierre, Zehn, Dietmar, James, Eddie, Nepom, Gerald, Youngblood, Ben, Deeks, Steven, Rutishauser, Rachel

المصدر: Nature Immunology, vol 21, iss 5

مصطلحات موضوعية: Adolescent, Adult, Animals, Autoantigens, CD8-Positive T-Lymphocytes, Cell Plasticity, Cells, Cultured, DNA Methylation, Diabetes Mellitus, Type 1, Epigenesis, Genetic, Female, Flow Cytometry, Humans, Immunologic Memory, Insulin-Secreting Cells, Male, Mice, Pluripotent Stem Cells, Single-Cell Analysis, Young Adult

وصف الملف: application/pdf

العلاقة: qt26g354xk; https://escholarship.org/uc/item/26g354xkTest

الإتاحة: https://escholarship.org/uc/item/26g354xkTest

المؤلفون: McLendon, Roger, Friedman, Allan, Bigner, Darrell, Van Meir, Erwin G, Brat, Daniel J, M. Mastrogianakis, Gena, Olson, Jeffrey J, Mikkelsen, Tom, Lehman, Norman, Aldape, Ken, Alfred Yung, WK, Bogler, Oliver, VandenBerg, Scott, Berger, Mitchel, Prados, Michael, Muzny, Donna, Morgan, Margaret, Scherer, Steve, Sabo, Aniko, Nazareth, Lynn, Lewis, Lora, Hall, Otis, Zhu, Yiming, Ren, Yanru, Alvi, Omar, Yao, Jiqiang, Hawes, Alicia, Jhangiani, Shalini, Fowler, Gerald, San Lucas, Anthony, Kovar, Christie, Cree, Andrew, Dinh, Huyen, Santibanez, Jireh, Joshi, Vandita, Gonzalez-Garay, Manuel L, Miller, Christopher A, Milosavljevic, Aleksandar, Donehower, Larry, Wheeler, David A, Gibbs, Richard A, Cibulskis, Kristian, Sougnez, Carrie, Fennell, Tim, Mahan, Scott, Wilkinson, Jane, Ziaugra, Liuda, Onofrio, Robert, Bloom, Toby, Nicol, Rob, Ardlie, Kristin, Baldwin, Jennifer, Gabriel, Stacey, Lander, Eric S, Ding, Li, Fulton, Robert S, McLellan, Michael D, Wallis, John, Larson, David E, Shi, Xiaoqi, Abbott, Rachel, Fulton, Lucinda, Chen, Ken, Koboldt, Daniel C, Wendl, Michael C, Meyer, Rick, Tang, Yuzhu, Lin, Ling, Osborne, John R, Dunford-Shore, Brian H, Miner, Tracie L, Delehaunty, Kim, Markovic, Chris, Swift, Gary, Courtney, William, Pohl, Craig, Abbott, Scott, Hawkins, Amy, Leong, Shin, Haipek, Carrie, Schmidt, Heather, Wiechert, Maddy, Vickery, Tammi, Scott, Sacha, Dooling, David J, Chinwalla, Asif, Weinstock, George M, Mardis, Elaine R, Wilson, Richard K, Getz, Gad, Winckler, Wendy, Verhaak, Roel GW, Lawrence, Michael S, O’Kelly, Michael, Robinson, Jim, Alexe, Gabriele, Beroukhim, Rameen, Carter, Scott, Chiang, Derek, Gould, Josh

المصدر: Nature. 455(7216)

مصطلحات موضوعية: Cancer, Human Genome, Genetic Testing, Brain Cancer, Genetics, Brain Disorders, Biotechnology, Rare Diseases, Aetiology, 2.1 Biological and endogenous factors, Adolescent, Adult, Aged, Aged, 80 and over, Brain Neoplasms, DNA Methylation, DNA Modification Methylases, DNA Repair, DNA Repair Enzymes, Female, Gene Dosage, Gene Expression Regulation, Neoplastic, Genes, Tumor Suppressor, Genes, erbB-1, Genome, Human, Genomics, Glioblastoma, Humans, Male, Middle Aged, Models, Molecular, Mutation, Neurofibromin 1, Phosphatidylinositol 3-Kinases, Protein Structure, Tertiary, Retrospective Studies, Signal Transduction, Tumor Suppressor Proteins, Cancer Genome Atlas Research Network, General Science & Technology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/18c2x2tpTest

المؤلفون: Cancer Genome Atlas Research Network

المصدر: Nature. 455(7216)

مصطلحات موضوعية: Cancer Genome Atlas Research Network, Humans, Glioblastoma, Brain Neoplasms, DNA Repair Enzymes, DNA Modification Methylases, Neurofibromin 1, Tumor Suppressor Proteins, Retrospective Studies, Genomics, Signal Transduction, DNA Methylation, DNA Repair, Gene Expression Regulation, Neoplastic, Protein Structure, Tertiary, Gene Dosage, Mutation, Genes, Tumor Suppressor, Genes, erbB-1, Genome, Human, Models, Molecular, Adolescent, Adult, Aged, Aged, 80 and over, Middle Aged, Female, Male, Phosphatidylinositol 3-Kinases, Biotechnology, Genetic Testing, Human Genome, Genetics, Cancer, Brain Disorders, Rare Diseases, Brain Cancer, 2.1 Biological and endogenous factors, General Science & Technology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/18c2x2tpTest

المؤلفون: Rafick-Pierre Sekaly, Elisavet Serti, Shannon K. Boi, Ashley H. Castellaw, Dietmar Zehn, Hai Nguyen, Hazem E. Ghoneim, Caitlin C. Zebley, Michael E. Busch, Mars Stone, Rachel L. Rutishauser, Francesca Alfei, Eddie A. James, Maureen A. McGargill, Cate Speake, Ben Youngblood, Jeremy Chase Crawford, Yiping Fan, Gerald T. Nepom, Steven G. Deeks, Hossam A. Abdelsamed, Susan Pereira Ribeiro, Shanta Alli, Hongjian Jin, Laurence A. Turka

المصدر: Nature immunology
Nature immunology, vol 21, iss 5
Nature Immunology

مصطلحات موضوعية: 0301 basic medicine, Male, Cell Plasticity, CD8-Positive T-Lymphocytes, Regenerative Medicine, Autoantigens, Epigenesis, Genetic, Mice, 0302 clinical medicine, Stem Cell Research - Nonembryonic - Human, Insulin-Secreting Cells, 2.1 Biological and endogenous factors, Immunology and Allergy, Cytotoxic T cell, Aetiology, Cells, Cultured, Cultured, Diabetes, Acquired immune system, Flow Cytometry, Cell biology, medicine.anatomical_structure, Female, Stem cell, Beta cell, Single-Cell Analysis, Type 1, Adult, Pluripotent Stem Cells, Adolescent, Cells, T cell, Immunology, Biology, Autoimmune Disease, Article, 03 medical and health sciences, Young Adult, Genetic, Diabetes Mellitus, Genetics, medicine, Animals, Humans, Epigenetics, Metabolic and endocrine, DNA Methylation, Stem Cell Research, 030104 developmental biology, Diabetes Mellitus, Type 1, T cell differentiation, Immunologic Memory, CD8, Epigenesis, 030215 immunology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89c766e2ff25c8b1dacf4caad1134276Test
http://europepmc.org/articles/PMC7183435Test

المؤلفون: Karin de Stricker, Wolfgang Brück, Eleonora Aronica, Felice Giangaspero, Benedicte Parm Ulhøi, Simone Schmid, Annika K. Wefers, Viktoria Ruf, David T.W. Jones, Christel Herold-Mende, Jeanette Krogh Petersen, Daniel Schrimpf, Andreas von Deimling, Henning B. Boldt, Maria Gardberg, David Capper, Karima Mokhtari, Felix Sahm, Philipp Sievers, Romain Appay, Stefan M. Pfister, Dominique Figarella-Branger, Sebastian Brandner, Bjarne Winther Kristensen, Martin Hasselblatt, Elisabeth J. Rushing, Wolfgang Wick, Daniel Hänggi, David E. Reuss, Pieter Wesseling, Annekathrin Reinhardt, Damian Stichel, Benoit Lhermitte, Franck Bielle, Roland Coras

المساهمون: Pathology, APH - Aging & Later Life, APH - Mental Health, CCA - Cancer biology and immunology

المصدر: Sievers, P, Appay, R, Schrimpf, D, Stichel, D, Reuss, D E, Wefers, A K, Reinhardt, A, Coras, R, Ruf, V C, Schmid, S, de Stricker, K, Boldt, H B, Kristensen, B W, Petersen, J K, Ulhøi, B P, Gardberg, M, Aronica, E, Hasselblatt, M, Brück, W, Bielle, F, Mokhtari, K, Lhermitte, B, Wick, W, Herold-Mende, C, Hänggi, D, Brandner, S, Giangaspero, F, Capper, D, Rushing, E, Wesseling, P, Pfister, S M, Figarella-Branger, D, von Deimling, A, Sahm, F & Jones, D T W 2019, ' Rosette-forming glioneuronal tumors share a distinct DNA methylation profile and mutations in FGFR1, with recurrent co-mutation of PIK3CA and NF1 ', Acta Neuropathologica, vol. 138, no. 3, pp. 497-504 . https://doi.org/10.1007/s00401-019-02038-4Test
Acta neuropathologica. Springer Verlag
Acta Neuropathologica, 138(3), 497-504. Springer Verlag

مصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, Male, PI3K, DNA methylation profile, 0302 clinical medicine, Rosette-forming glioneuronal tumor, Child, Neurons, Neurofibromin 1, molecular classification, Brain Neoplasms, Glioma, Middle Aged, Molecular classification, DNA methylation, Female, Signal transduction, RGNT, brain tumor, Adult, Tumor suppressor gene, Adolescent, Class I Phosphatidylinositol 3-Kinases, Brain tumor, Biology, Pathology and Forensic Medicine, 03 medical and health sciences, Cellular and Molecular Neuroscience, Young Adult, medicine, FGFR1, MAPK, NF1, PIK3CA, Humans, Epigenetics, Receptor, Fibroblast Growth Factor, Type 1, PI3K/AKT/mTOR pathway, Aged, Retrospective Studies, Fibroblast growth factor receptor 1, DNA Methylation, medicine.disease, 030104 developmental biology, Mutation, Cancer research, Neurology (clinical), 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0ab0d7f5eec9657ea5ed00f5c715f09Test
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85068114873&origin=inwardTest

المؤلفون: Gabriel Capellá, Laura Valle, Matilde Navarro, Mariona Terradas, Gemma Aiza, Sami Belhadj, Pau M. Munoz-Torres

المصدر: Human Mutation. 41:1563-1576

مصطلحات موضوعية: Adult, Candidate gene, Adolescent, Colorectal cancer, DNA Mutational Analysis, Biology, Cohort Studies, Young Adult, 03 medical and health sciences, Germline mutation, Genetics, medicine, Humans, Genetic Predisposition to Disease, Epigenetics, Promoter Regions, Genetic, Allele frequency, Interleukin 12 receptor, beta 1 subunit, Gene, Early Detection of Cancer, Genetics (clinical), Aged, 030304 developmental biology, Aged, 80 and over, 0303 health sciences, FAN1, Receptor-Like Protein Tyrosine Phosphatases, Class 3, 030305 genetics & heredity, DNA Methylation, Middle Aged, medicine.disease, Colorectal Neoplasms

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::197a3bdc5838a6fac0b33aa6572329f8Test
https://doi.org/10.1002/humu.24057Test

المؤلفون: Janet R. Vos, Sera Langenveld, Liesbeth Spruijt, Ingrid E Fakkert, Edward M Leter, Marjolijn J. L. Ligtenberg, Arjen R. Mensenkamp, Riki W. Willems, Nicoline Hoogerbrugge, Iris D. Nagtegaal

المساهمون: MUMC+: DA KG Polikliniek (9), RS: FHML non-thematic output

المصدر: International Journal of Cancer
International Journal of Cancer, 147, 2150-2158
International Journal of Cancer, 147, 8, pp. 2150-2158
International Journal of Cancer, 147(8), 2150-2158. Wiley

مصطلحات موضوعية: Male, Oncology, Cancer Research, Cancer Genetics And Epigenetics, Colorectal cancer, diagnosis, germline, DNA Mismatch Repair, Germline, Tumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14], 0302 clinical medicine, Tumours of the digestive tract Radboud Institute for Molecular Life Sciences [Radboudumc 14], somatic mutation, Prospective Studies, guidelines, Promoter Regions, Genetic, Prospective cohort study, risk, mechanisms, Women's cancers Radboud Institute for Molecular Life Sciences [Radboudumc 17], medicine.diagnostic_test, Middle Aged, Lynch syndrome, germline mutation, mlh1, 030220 oncology & carcinogenesis, Female, DNA mismatch repair, recognition, Colorectal Neoplasms, MutL Protein Homolog 1, Rare cancers Radboud Institute for Health Sciences [Radboudumc 9], Adult, medicine.medical_specialty, congenital, hereditary, and neonatal diseases and abnormalities, Adolescent, colorectal cancer, MLH1, Young Adult, 03 medical and health sciences, Germline mutation, Internal medicine, medicine, Humans, Genetic Testing, neoplasms, Aged, Genetic testing, business.industry, mismatch repair deficiency, DNA Methylation, medicine.disease, Colorectal Neoplasms, Hereditary Nonpolyposis, digestive system diseases, Mutation, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b685957977e871f78f34fcb5896bfd22Test
http://europepmc.org/articles/PMC7496272Test