المؤلفون: Thomas Laeger, Louise Fritsche, Christian Baumeier, Norbert Stefan, Annette Schürmann, Sophie Saussenthaler, Andreas Fritsche, Robert W. Schwenk, Maria Rödiger, Hans-Ulrich Häring, Luisa Schlüter, Stella Amelie Alaze

المصدر: Molecular Metabolism
Mol. Metab. 6, 1254-1263 (2017)
Molecular Metabolism, Vol 6, Iss 10, Pp 1254-1263 (2017)

مصطلحات موضوعية: 0301 basic medicine, Male, HFD, high-fat diet, PPARγ, medicine.medical_treatment, CD36, Adipose tissue, AST, aspartate aminotransferase, SM, skeletal muscle, Mice, F4/80, adhesion G protein-coupled receptor E1, GGT, gamma-glutamyl transpeptidase, Non-alcoholic Fatty Liver Disease, Insulin, rmDPP4, recombinant mouse dipeptidyl peptidase 4, rhDPP4, recombinant human dipeptidyl peptidase 4, Fatty liver, Ad, adenovirus, sWAT, subcutaneous white adipose tissue, Hep G2 Cells, Middle Aged, Dgat2, diacylglycerol O-acyltransferase 2, Cd36, Dpp4, Glp-1, Insulin Resistance, Nafld, Pparγ, TNFα, tumor necrosis factor α, Liver, Cpt1a, carnitine palmitoyltransferase 1a, MOGAT1, monoacylglycerol O-acyltransferase 1, Original Article, Female, medicine.symptom, PPARγ, peroxisome proliferator activated receptor gamma, Dpp4-Liv-Tg, transgenic mice with hepatocyte-specific Dpp4 overexpression, NFκB, nuclear factor-κB, Adult, lcsh:Internal medicine, medicine.medical_specialty, NAFLD, non-alcoholic fatty liver disease, Akt, Akt serine–threonine protein kinase, HOMA-IR, homeostatic model assessment for insulin resistance, IL6, interleukin 6, NASH, non-alcoholic steatohepatitis, Dipeptidyl Peptidase 4, gWAT, gonadal white adipose tissue, Inflammation, Srebf1, sterol regulatory element binding transcription factor 1, Mice, Transgenic, Biology, DPP4, 03 medical and health sciences, Insulin resistance, Internal medicine, NAFLD, ALT, alanine aminotransferase, medicine, Animals, Humans, ApoB, apolipoprotein B, GLP-1, glucagon-like peptide 1, Obesity, lcsh:RC31-1245, Molecular Biology, pAkt, phosphorylated Akt serine–threonine protein kinase, Cell Biology, medicine.disease, CD36, fatty acid translocase, DPP4, dipeptidyl peptidase 4, WT, wild-type, BAT, brown adipose tissue, Insulin receptor, Disease Models, Animal, 030104 developmental biology, Endocrinology, biology.protein, Hepatocytes, Gfp, green fluorescent protein, Steatosis, GLP-1, MCP1, chemokine (C-C motif) ligand 2, MAPK, mitogen-activated protein kinase

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec108ccaaae2e081b54e4ea79fe8b459Test

المؤلفون: Mayumi Nagashimada, Eric Mayoux, Naoto Nagata, Guanliang Chen, Liang Xu, Shuichi Kaneko, Yinhua Ni, Fen Zhuge, Tsuguhito Ota

المصدر: EBioMedicine
EBioMedicine, Vol 20, Iss C, Pp 137-149 (2017)

مصطلحات موضوعية: Male, 0301 basic medicine, HFD, high-fat diet, FGF21, Macrophage, lcsh:Medicine, AST, aspartate aminotransferase, White adipose tissue, 030204 cardiovascular system & hematology, ATMs, adipose tissue macrophages, Brown adipose tissue, EGP, endogenous glucose production, Mice, 0302 clinical medicine, Glucosides, FACS, fluorescence-activated cell sorting, TBARS, thiobarbituric acid reactive substances, Empa, empagliflozin, RER, respiratory exchange ratio, Adiposity, lcsh:R5-920, Glucose tolerance test, medicine.diagnostic_test, NEFA, non-esterified fatty acid, Fatty Acids, CT, computed tomographic, WAT, white adipose tissue, DIO, high-fat-diet-induced obese, General Medicine, TG, triglycerides, Adipose Tissue, H&E, haematoxylin and eosin, GTT, glucose tolerance test, lcsh:Medicine (General), Oxidation-Reduction, Research Paper, NAFLD, non-alcoholic fatty liver disease, medicine.medical_specialty, NASH, non-alcoholic steatohepatitis, Adipose tissue macrophages, Biology, Diet, High-Fat, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Insulin resistance, VCO2, carbon dioxide production, FGF21, fibroblast growth factor, Internal medicine, UCP1, uncoupling protein 1, medicine, Empagliflozin, Animals, Hypoglycemic Agents, Obesity, Benzhydryl Compounds, Muscle, Skeletal, Sodium-Glucose Transporter 2 Inhibitors, ITT, insulin tolerance test, VO2, oxygen consumption, Inflammation, Macrophages, lcsh:R, SGLT, sodium/glucose cotransporter, Sodium glucose cotransporter-2 inhibitor, Body Weight, Insulin tolerance test, ALT, Alanine aminotransferase, Energy metabolism, UGE, urinary glucose excretion, Macrophage Activation, medicine.disease, BAT, brown adipose tissue, TC, total cholesterol, Fatty Liver, AMPK, AMP-activated protein kinase, Glucose, 030104 developmental biology, Endocrinology, Insulin Resistance, LMs, liver macrophages, Diet-induced obese, Biomarkers

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c85fd9e3671e9effaeef0acf4b89dd1Test
https://doi.org/10.1016/j.ebiom.2017.05.028Test

المؤلفون: Irene Locatelli, Francesco Vizzutti, N. Navari, Emanuele Albano, Alessandra Caligiuri, Erica Novo, Maurizio Parola, Massimo Pinzani, W. Delogu, E. Zamara, Fabio Marra, Salvatore Sutti, S. Galastri, E. Vivoli, A. Provenzano, Stefano Milani

المصدر: Clinical Science (London, England : 1979)
Clinical Science
Clinical Science; Vol 123

مصطلحات موضوعية: Liver Cirrhosis, HNE, 4-hydroxynonenal, IFN-γ, interferon-γ, Adipose tissue, AST, aspartate aminotransferase, iNOS, inducible NO synthase, chemistry.chemical_compound, Mice, 0302 clinical medicine, CC chemokine ligand 2, Fibrosis, Transforming Growth Factor beta, cytokine, Chemokine CCL2, liver fibrosis, Mice, Knockout, 0303 health sciences, TIMP-1, tissue inhibitor of metalloproteinases-1, Mice, Inbred BALB C, Fatty liver, CCL2, CC chemokine ligand 2, General Medicine, MGL1, macrophage galactose-type C-type lectin 1, GAPDH, glyceraldehyde-3-phosphate dehydrogenase, TNFα, tumour necrosis factor α, 030211 gastroenterology & hepatology, non-alcoholic steatohepatitis, Research Article, medicine.medical_specialty, NAFLD, non-alcoholic fatty liver disease, ALT, alanine transaminase, NASH, non-alcoholic steatohepatitis, Biology, S2, Collagen Type I, 03 medical and health sciences, ROS, reactive oxygen species, Species Specificity, Internal medicine, TGF-β, transforming growth factor-β, medicine, Hepatic Stellate Cells, Animals, Sirius Red, 030304 developmental biology, KO, knockout, Tissue Inhibitor of Metalloproteinase-1, Macrophages, chemokine, medicine.disease, WT, wild-type, Dietary Fats, IL, interleukin, Fatty Liver, Mice, Inbred C57BL, Disease Models, Animal, Oxidative Stress, Endocrinology, chemistry, Alanine transaminase, Immunology, CCR2, CC chemokine receptor 2, Hepatic stellate cell, biology.protein, Steatosis, Steatohepatitis, RT, real-time, FAM, 6-carboxyfluorescein, MCD diet, methionine/choline-deficient diet

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6301da5ba54f78553e0c47b589df9625Test
http://europepmc.org/articles/PMC3369401Test

المؤلفون: Pooja, Jha, Astrid, Knopf, Harald, Koefeler, Michaela, Mueller, Carolin, Lackner, Gerald, Hoefler, Thierry, Claudel, Michael, Trauner

المصدر: Biochimica et Biophysica Acta

مصطلحات موضوعية: SNS, sympathetic nervous system, 18:1n9, Oleic acid, 16:1n7, Palmitoleic acid, FGF21, fibroblast growth factor 21, Fatty Acids, Nonesterified, MCD, methionine–choline-deficient, Choline, 20:4n6, Arachidonic acid, Mice, Methionine, FGF21, HSL, hormone sensitive lipase, Non-alcoholic Fatty Liver Disease, PCYT2, ethanolamine-phosphate cytidylyltransferase 2, HSL, 24:0, Lignoceric acid, Adipogenesis, PPARγ2, peroxisome proliferator-activated receptor γ2, TG, triglyceride, NEFA, non-esterified fatty acid, Fatty Acids, PEMT, phosphatidylethanolamine N-methyltransferase, SREBP1c, sterol regulatory element-binding protein 1c, ACC1, acetyl-CoA carboxylase, Cox4i1, cytochrome c oxidase subunit IV isoform 1, 18:3n3, αLinolenic acid, C/EBPα, CCAAT/enhancer-binding protein alpha, Adipose Tissue, Liver, 20:5n3, Eicosapentaenoic acid (EPA), 22:6n3, Docosahexaenoic acid, ATP5B, ATP synthase, H + transporting mitochondrial F1 complex, beta subunit, Oxidation-Reduction, IHC, immunohistochemistry, NAFLD, non-alcoholic fatty liver disease, ap2/FABP4, adipocyte protein 2/fatty acid binding protein 4, Lipolysis, NASH, non-alcoholic steatohepatitis, DNL, de novo lipogenesis, ACSL1, long-chain fatty-acid-coenzyme A ligase, Article, CPT1β, carnitine palmitoyltransferase 1β, ATGL, DGAT, diglyceride acyltransferase, PCYT1A, choline-phosphate cytidylyltransferase A, WAT, white adipose tissue. Common name of fatty acids: 14:0 Myristic acid, NAFLD, Animals, Obesity, Inflammation, 18:1n11, Vaccenic acid, ATGL, adipose triglyceride lipase, FA, fatty acid, UCP-1, uncoupling protein 1, 18:3n6, γLinolenic acid, nutritional and metabolic diseases, SCD1, stearoyl-CoA desaturase-1, 18:2n6, Linoleic acid, Lipase, 22:5n3, Docosapentaenoic acid (DPA), Lipid Metabolism, 20:3n6, Dihomo γlinolenic acid, 20:0, Aracidic acid, Fatty Liver, Fibroblast Growth Factors, BAT, brown adipose tissue, Disease Models, Animal, SD, standard deviation, 16:0, Palmitic acid, TFA, total fatty acid, 18:0, Stearic acid, 22:4n6, Adrenic acid, CIDEA, cell death-inducing DFFA-like effector A

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::2cd4854fd8922691ea033f114aa71e03Test
https://pubmed.ncbi.nlm.nih.gov/24594481Test