التفاصيل البيبلوغرافية
| العنوان: |
Optical Coherence Tomography of Coronary Plaque Progression and Destabilization: JACC Focus Seminar Part 3/3. |
| المؤلفون: |
Adriaenssens, Tom1 (AUTHOR), Allard-Ratick, Marc P.1,2 (AUTHOR), Thondapu, Vikas1,3 (AUTHOR), Sugiyama, Tomoyo4 (AUTHOR), Raffel, O. Christopher5 (AUTHOR), Barlis, Peter6 (AUTHOR), Poon, Eric K.W.6 (AUTHOR), Araki, Makoto2 (AUTHOR), Nakajima, Akihiro2 (AUTHOR), Minami, Yoshiyasu7 (AUTHOR), Takano, Masamichi8 (AUTHOR), Kurihara, Osamu8 (AUTHOR), Fuster, Valentin9,10 (AUTHOR), Kakuta, Tsunekazu4 (AUTHOR), Jang, Ik-Kyung1,2,11 (AUTHOR) ijang@mgh.harvard.edu |
| المصدر: |
Journal of the American College of Cardiology (JACC). Sep2021, Vol. 78 Issue 12, p1275-1287. 13p. |
| مصطلحات موضوعية: |
*OPTICAL coherence tomography, *ATHEROSCLEROTIC plaque, *CORONARY artery disease, *COMPUTATIONAL fluid dynamics, *ACUTE coronary syndrome, *ATHEROSCLEROSIS complications, *DISEASE progression, *DIAGNOSTIC imaging, *ATHEROSCLEROSIS, *CORONARY circulation, *HEMODYNAMICS, *ALGORITHMS |
| مستخلص: |
The development of optical coherence tomography (OCT) has revolutionized our understanding of coronary artery disease. In vivo OCT research has paralleled with advances in computational fluid dynamics, providing additional insights in the various hemodynamic factors influencing plaque growth and stability. Recent OCT studies introduced a new concept of plaque healing in relation to clinical presentation. In addition to known mechanisms of acute coronary syndromes such as plaque rupture and plaque erosion, a new classification of calcified plaque was recently reported. This review will focus on important new insights that OCT has provided in recent years into coronary plaque development, progression, and destabilization, with a focus on the role of local hemodynamics and endothelial shear stress, the layered plaque (signature of previous subclinical plaque destabilization and healing), and the calcified culprit plaque. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
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