المؤلفون: Melchiorre C., Antonello A., Banzi R., Bolognesi M. L., Minarini A., Rosini M., Tumiatti V.

المساهمون: Melchiorre C., Antonello A., Banzi R., Bolognesi M.L., Minarini A., Rosini M., Tumiatti V.

مصطلحات موضوعية: Acetylcholinesterase, protein, Muscarinic receptor, Nicotinic receptor, Polyamine, Universal template

وصف الملف: ELETTRONICO

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/12500289; info:eu-repo/semantics/altIdentifier/wos/WOS:000181035600004; volume:23; issue:2; firstpage:200; lastpage:233; numberofpages:34; journal:MEDICINAL RESEARCH REVIEWS; https://hdl.handle.net/11585/955519Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-0037369134

الإتاحة: https://doi.org/10.1002/med.10029Test
https://hdl.handle.net/11585/955519Test

المؤلفون: Andrea Cavalli, Anna Minarini, Antonino Cattaneo, Michela Rosini, Andrea Tarozzi, Vincenza Andrisano, Maria Laura Bolognesi, Patrizia Hrelia, Giorgio Lenaz, Rita Banzi, Manuela Bartolini, Christian Bergamini, Carlo Melchiorre, Romana Fato, Vincenzo Tumiatti, Maurizio Recanatini

المساهمون: Bolognesi ML, Banzi R, Bartolini M, Cavalli A, Tarozzi A, Andrisano V, Minarini A, Rosini M, Tumiatti V, Bergamini C, Fato R, Lenaz G, Hrelia P, Cattaneo A, Recanatini M, Melchiorre C., Bolognesi, Ml, Banzi, R, Bartolini, M, Cavalli, A, Tarozzi, A, Andrisano, V, Minarini, A, Rosini, M, Tumiatti, V, Bergamini, C, Fato, R, Lenaz, G, Hrelia, P, Cattaneo, Antonino, Recanatini, M, Melchiorre, C.

المصدر: Journal of medicinal chemistry. 50(20)

مصطلحات موضوعية: Models, Molecular, Amyloid beta, Plasma protein binding, medicine.disease_cause, Ligands, Antioxidants, MULTITARGET, Cell Line, Substrate Specificity, chemistry.chemical_compound, Structure-Activity Relationship, Alzheimer Disease, Drug Discovery, medicine, NAD(P)H Dehydrogenase (Quinone), Polyamines, Structure–activity relationship, Humans, Binding site, Butyrylcholinesterase, Amyloid beta-Peptides, Binding Sites, biology, Chemistry, Quinones, medicine.disease, AMYLOID-BETA, Acetylcholinesterase, Oxidative Stress, Biochemistry, ALZHEIMER'S DISEASE, biology.protein, Molecular Medicine, Cholinesterase Inhibitors, Alzheimer's disease, Reactive Oxygen Species, Oxidative stress, Protein Binding

وصف الملف: STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1ae0f0f5155ca76a5f3596bd588cb39Test
https://pubmed.ncbi.nlm.nih.gov/17850125Test

المؤلفون: Carlo Melchiorre, Andrea Milelli, Vincenzo Tumiatti, Michela Rosini, Anna Minarini, Maria Laura Bolognesi

المساهمون: Tumiatti V., Minarini A., Bolognesi M.L., Milelli A., Rosini M., Melchiorre C.

المصدر: Current Medicinal Chemistry. 17:1825-1838

مصطلحات موضوعية: Models, Molecular, Disease, Pharmacology, Biochemistry, Structure-Activity Relationship, chemistry.chemical_compound, Alzheimer Disease, Biological profile, Drug Discovery, medicine, Humans, TACRINE HETERODIMERS, Amyloid beta-Peptides, DUAL BINDING ACETYLCHOLINESTERASE INHIBITORS, business.industry, Organic Chemistry, medicine.disease, Acetylcholinesterase, chemistry, Tacrine, MULTI-TARGET-DIRECTED LIGANDS (MTDLS), Molecular Medicine, Cholinesterase Inhibitors, Alzheimer's disease, NEURODEGENERATIVE DISEASES, business, medicine.drug

وصف الملف: STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59c756a4aaec2c3b4201e195902f410aTest
https://doi.org/10.2174/092986710791111206Test

المؤلفون: Maria Laura Bolognesi, Anna Minarini, Vincenza Andrisano, Vincenzo Tumiatti, Michela Rosini, Maurizio Recanatini, Manuela Bartolini, Carlo Melchiorre, Andrea Cavalli

المساهمون: Bolognesi M. L., Andrisano V., Bartolini M., Cavalli A., Minarini A., Recanatini M., Rosini M., Tumiatti V., Melchiorre C.

المصدر: Il Farmaco. 60:465-473

مصطلحات موضوعية: Acylation, Physostigmine, Allosteric regulation, Phenylcarbamates, Pharmaceutical Science, Rivastigmine, Pharmacology, chemistry.chemical_compound, Alzheimer Disease, Heterocyclic Compounds, Drug Discovery, Catalytic triad, medicine, Humans, Binding site, chemistry.chemical_classification, Binding Sites, Molecular Structure, Chemistry, Acetylcholinesterase, Enzyme, Biochemistry, Cholinergic, Cholinesterase Inhibitors, Propidium, medicine.drug

وصف الملف: STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baae35ef740363039a4e885065e7c27dTest
https://doi.org/10.1016/j.farmac.2005.03.010Test

المؤلفون: Maria Laura Bolognesi, Vincenza Andrisano, and Andrea Tarozzi, Anna Minarini, Manuela Bartolini, Patrizia Hrelia, Michela Rosini, Carlo Melchiorre

المساهمون: ROSINI M., ANDRISANO V., BARTOLINI M., BOLOGNESI M. L., HRELIA P., MINARINI A., TAROZZI A., MELCHIORRE C.

المصدر: Journal of Medicinal Chemistry. 48:360-363

مصطلحات موضوعية: Pharmacology, Antioxidants, Cell Line, Structure-Activity Relationship, chemistry.chemical_compound, Alzheimer Disease, Biological property, Drug Discovery, medicine, Humans, Structure–activity relationship, Nootropic Agents, Neurons, chemistry.chemical_classification, Reactive oxygen species, Amyloid beta-Peptides, Anti alzheimer, Thioctic Acid, Lipoic acid, chemistry, Butyrylcholinesterase, Tacrine, Acetylcholinesterase, Molecular Medicine, Cholinesterase Inhibitors, Pharmacophore, Reactive Oxygen Species, Lead compound, medicine.drug

وصف الملف: STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8aee38e5f1df968b2a0f1d0c510da24Test
https://doi.org/10.1021/jm049112hTest

المؤلفون: Carlo Melchiorre, Glauco Tarozzo, Andrea Cavalli, Daniela Pizzirani, Luca Goldoni, Giovanni Bottegoni, Maria Letizia Trincavelli, Angelo Reggiani, Elena Simoni, Michela Rosini, Claudia Martini, Simona Daniele, Daniele Piomelli

المساهمون: Simoni E., Daniele S., Bottegoni G., Pizzirani D., Trincavelli M.L., Goldoni L., Tarozzo G., Reggiani A., Martini C., Piomelli D., Melchiorre C., Rosini M., Cavalli A.

المصدر: Simoni, E; Daniele, S; Bottegoni, G; Pizzirani, D; Trincavelli, ML; Goldoni, L; et al.(2012). Combining galantamine and memantine in multitargeted, new chemical entities potentially useful in Alzheimer's disease. Journal of Medicinal Chemistry, 55(22), 9708-9721. doi: 10.1021/jm3009458. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/86n0q0gkTest

مصطلحات موضوعية: Male, Aché, Pharmacology, Receptors, N-Methyl-D-Aspartate, Neuroprotection, Rats, Sprague-Dawley, Neuroblastoma, chemistry.chemical_compound, Alzheimer Disease, Memantine, Galantamine, medicine, Animals, Humans, Computer Simulation, MEDICINAL CHEMISTRY, Receptor, Cell Proliferation, Cerebral Cortex, Chemistry, Neurotoxicity, medicine.disease, COMPUTATIONAL CHEMISTRY, Acetylcholinesterase, language.human_language, Rats, DRUG DISCOVERY, Drug Combinations, Neuroprotective Agents, Biochemistry, ALZHEIMER'S DISEASE, nervous system, Drug Design, language, Feasibility Studies, Molecular Medicine, NMDA receptor, Cholinesterase Inhibitors, medicine.drug

وصف الملف: application/pdf; STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c9e2da329aa1c0e8d1b4bb0f632c25bTest
http://www.escholarship.org/uc/item/86n0q0gkTest

المؤلفون: Carlo Melchiorre, Maria Laura Bolognesi, Anna Minarini, Michela Rosini, Elena Simoni, Vincenzo Tumiatti

المساهمون: Bolognesi M.L., Simoni E., Rosini M., Minarini A., Tumiatti V., Melchiorre C

مصطلحات موضوعية: Drug, media_common.quotation_subject, Computational biology, Disease, Pharmacology, Ligands, Alzheimer Disease, Alkanes, medicine, Ethylamines, Animals, Humans, Enzyme Inhibitors, media_common, Amyloid beta-Peptides, Thioctic Acid, Drug discovery, business.industry, General Medicine, DRUG DISCOVERY, Tacrine, Molecular targets, Acetylcholinesterase, business, NEURODEGENERATIVE DISEASES, medicine.drug

وصف الملف: STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd763a546e1db61961b2fdbedbe66576Test
http://hdl.handle.net/11585/108616Test

المؤلفون: Gianpaolo Chiriano, Maria Laura Bolognesi, Giovanni Bottegoni, Manfred Windisch, Vincenzo Tumiatti, Michela Rosini, Carlo Melchiorre, Manuela Bartolini, Andrea Cavalli, Vincenza Andrisano, Valentina Maestri, Anna Minarini, Stefan Czvitkovich, Francesca Mancini

المساهمون: Bolognesi ML, Chiriano G, Bartolini M, Mancini F, Bottegoni G, Maestri V, Czvitkovich S, Windisch M, Cavalli A, Minarini A, Rosini M, Tumiatti V, Andrisano V, Melchiorre C.

مصطلحات موضوعية: Models, Molecular, Aché, Stereochemistry, Cell Survival, Molecular Conformation, In Vitro Techniques, Ligands, Bivalent (genetics), chemistry.chemical_compound, Structure-Activity Relationship, Catalytic Domain, Drug Discovery, Alkanes, Ethylamines, Animals, Humans, Neurons, Amyloid beta-Peptides, ALZHEIMER’S DISEASE, Affinities, language.human_language, In vitro, Peptide Fragments, APP metabolism, Monomer, chemistry, Butyrylcholinesterase, Amyloid aggregation, language, Acetylcholinesterase, Molecular Medicine, Cholinesterase Inhibitors, Amyloid Precursor Protein Secretases, Chickens, Protein Binding

وصف الملف: STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6915ab35436d2c99c205c324dfb6ba17Test
http://hdl.handle.net/11585/109307Test

المؤلفون: Michela Rosini, Federica Lizzi, Maria Laura Bolognesi, Andrea Milelli, Carlo Melchiorre, Manuela Bartolini, Vincenza Andrisano, Anna Minarini, Patrizia Hrelia, Andrea Tarozzi, Fabiana Morroni

المساهمون: Bolognesi M.L., Bartolini M., Tarozzi A., Morroni F., Lizzi F., Milelli A., Minarini A., Rosini M., Hrelia P., Andrisano V., Melchiorre C.

المصدر: Bioorganicmedicinal chemistry letters. 21(9)

مصطلحات موضوعية: Amyloid, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, chemistry.chemical_compound, Inhibitory Concentration 50, Drug Delivery Systems, Alzheimer Disease, Alkanes, Drug Discovery, Ethylamines, Humans, Benzofuran, Enzyme Inhibitors, Molecular Biology, Cells, Cultured, Amyloid beta-Peptides, biology, Molecular Structure, Drug discovery, Organic Chemistry, Acetylcholinesterase, Benzothiazole, chemistry, Enzyme inhibitor, biology.protein, Curcumin, Molecular Medicine, Cholinesterase Inhibitors, NEURODEGENERATIVE DISEASES, Lead compound

وصف الملف: STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aa91f4f7ca1dbc2cea971772e8437b5Test
https://pubmed.ncbi.nlm.nih.gov/21236667Test

المؤلفون: Carlo Melchiorre, Michela Rosini, Maria Laura Bolognesi, Manuela Bartolini, Vincenza Andrisano

المساهمون: Bolognesi ML, Bartolini M, Rosini M, Andrisano V, Melchiorre C.

المصدر: Bioorganicmedicinal chemistry letters. 19(15)

مصطلحات موضوعية: Stereochemistry, Clinical Biochemistry, Substituent, Pharmaceutical Science, Biochemistry, Chemical synthesis, chemistry.chemical_compound, Inhibitory Concentration 50, Mice, Structure-Activity Relationship, Alzheimer Disease, Drug Discovery, Alkanes, medicine, Ethylamines, Polyamines, Animals, Humans, Amines, Molecular Biology, Amyloid beta-Peptides, Dose-Response Relationship, Drug, Hydrolysis, Organic Chemistry, Diastereomer, Quinones, Stereoisomerism, Acetylcholinesterase, Small molecule, Mechanism of action, chemistry, Models, Chemical, Molecular Medicine, medicine.symptom, Enantiomer, Chirality (chemistry)

وصف الملف: STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4b025f3491fb5e46f3a95538cd7d07bTest
https://pubmed.ncbi.nlm.nih.gov/19505825Test