التفاصيل البيبلوغرافية
| العنوان: |
Adverse Reactions Due to the Bacillus Calmette--Guerin Vaccine: Twenty Tunisian Cases. |
| المؤلفون: |
Sellami, Khadija, Amouri, Meriem, Kmiha, Sana, Bahloul, Emna, Aloulou, Hajer, Sfaihi, Lamia, Guirat, R., Mseddi, Madiha, Kamoun, T., Hachicha, Mongia, Turki, Hamida |
| المصدر: |
Indian Journal of Dermatology; Jan/Feb2018, Vol. 63 Issue 1, p62-65, 4p |
| مصطلحات موضوعية: |
ACADEMIC medical centers, BCG vaccines, DRUG side effects, RETROSPECTIVE studies |
| مصطلحات جغرافية: |
TUNISIA |
| مستخلص: |
Background: Bacillus Calmette-Guérin (BCG) vaccine is a widely used vaccine. Management of local BCG complications differs between clinicians, and the optimal approach remains unclear. Aims: We aim to describe the epidemiological, clinical and therapeutic aspects of the BCG vaccine side effects in Sfax. Patients and Methods: This was a retrospective study of all the cases of BCG vaccine adverse reactions recorded in the Dermatology and Paediatrics Departments of Hedi Chaker University Hospital of Sfax over a period of 10 years (2005-2015). Results: Twenty cases of BCG adverse reactions were notified during the study period. Actually, 80% of the patients presented local adverse reactions. The outcome was good in all the followed patients. The rate of disseminated BCG disease was 20%. Biological tests of immunity showed a primary immunodeficiency in three cases, whereas the outcome was fatal in two cases. Conclusion: BCG vaccine adverse reactions range from mild to severe. However, the management of benign local reactions remains unclear. Disseminated BCG disease must alert clinicians to the possibility of a primary immunodeficiency. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
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