Sinus bradycardia as the initial manifestation of multisystem inflammatory syndrome in children
| العنوان: | Sinus bradycardia as the initial manifestation of multisystem inflammatory syndrome in children |
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| المؤلفون: | Maria Mateu, I.J. Mendoza Britto, Karina Gonzalez, R Ortega, E Marcano, Igor Morr, F Sonshire, D Falcon, J De Izaguirre, I.J. Mendoza Mujica, A Cardenas |
| المصدر: | European Heart Journal |
| بيانات النشر: | Oxford University Press (OUP), 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Bradycardia, medicine.medical_specialty, business.industry, Sinus bradycardia, Holter Electrocardiography, Chest ct, Cardiac arrhythmia, medicine.disease, Abstract Supplement, Pericardial effusion, Clinical, Internal medicine, Shock (circulatory), medicine, Cardiology, AcademicSubjects/MED00200, cardiovascular diseases, medicine.symptom, Cardiology and Cardiovascular Medicine, business |
| الوصف: | Background While cardiovascular complications, including arrhythmias are now a recognized manifestation of Multisystem inflammatory syndrome in children (MIS-C), there are no reports of primary bradycardia preceding the clinical presentation. We sought to describe a case series of sinus bradycardia as an initial manifestation of MIS-C. Methods We included a series of 10 consecutive patients with confirmed COVID-19 who met WHO and CDC criteria for MIS-C, who developed sinus bradycardia with a heart rate measured in the awake state that was below the normal range for age for children, as an initial manifestation of the disease, in a prospective observational multicenter study. Patients underwent clinical, laboratory evaluation, ECG, Holter, telemetry, echocardiogram, chest X Ray, and a chest CT scan. Results Of the 10 patients included, 6 were male, with a mean age of 6.52±5.35 years, range 4 months to 14 years. All cases were Hispanic. Bradycardia was transient and did not merit treatment. Coronary abnormalities were noted in 6 cases; 4 patients had mild coronary ectasia; 9 patients had pericardial effusion with no evidence of tamponade. All patients had a mild clinical course; none had shock, heart failure, the need for mechanical ventilation, or died. All blood markers (Troponin, BNP, Platelet count, C-reactive protein, D-dimer, Ferritin) returned to normal levels by discharge/follow-up with a favorable outcome including resolution of coronary dilatation in all but 2 in which aneurysm persisted. Treatment All patients received steroids and low-weight-molecular heparin 10 patients, 8 aspirin and 8 intravenous immunoglobulins. Conclusion Sinus bradycardia may be the initial manifestation of MIS-C, usually transient and mild. Physicians should be aware of this presentation. Funding Acknowledgement Type of funding sources: None. Kid, MIS-C. Bradycardia/Atrial Rhythm |
| تدمد: | 1522-9645 0195-668X |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d76e504c11687ece59336fbdbd030ac8Test https://doi.org/10.1093/eurheartj/ehab724.0412Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....d76e504c11687ece59336fbdbd030ac8 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15229645 0195668X |
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