المؤلفون: Rantanen, Laura M., Bitar, Maina, Lampinen, Riikka, Stewart, Romal, Quek, Hazel, Oikari, Lotta E., Cuni-Lopez, Carla, Sutharsan, Ratneswary, Thillaiyampalam, Gayathri, Iqbal, Jamila, Russell, Daniel, Penttila, Elina, Lopponen, Heikki, Lehtola, Juha-Matti, Saari, Toni, Hannonen, Sanna, Koivisto, Anne M., Haupt, Larisa M., Mackay-Sim, Alan, Cristino, Alexandre S., Kanninen, Katja M., White, Anthony R.

المساهمون: Department of Neurosciences, University of Helsinki, HUS Neurocenter, Neurologian yksikkö

مصطلحات موضوعية: Akap6, Alzheimer's disease, RNA Sequencing, Aging, Cognition, Mild cognitive impairment, Olfactory neurosphere-derived cells, Patient-derived olfactory mucosa, 1182 Biochemistry, cell and molecular biology, 3112 Neurosciences, 3124 Neurology and psychiatry

وصف الملف: application/pdf

العلاقة: Rantanen , L M , Bitar , M , Lampinen , R , Stewart , R , Quek , H , Oikari , L E , Cuni-Lopez , C , Sutharsan , R , Thillaiyampalam , G , Iqbal , J , Russell , D , Penttila , E , Lopponen , H , Lehtola , J-M , Saari , T , Hannonen , S , Koivisto , A M , Haupt , L M , Mackay-Sim , A , Cristino , A S , Kanninen , K M & White , A R 2022 , ' An Alzheimer's Disease Patient-Derived Olfactory Stem Cell Model Identifies Gene Expression Changes Associated with Cognition ' , Cells , vol. 11 , no. 20 , 3258 . https://doi.org/10.3390/cells11203258Test; c64e6de2-0264-4cc9-9fbe-b0d185ee69e5; http://hdl.handle.net/10138/572248Test; 000872406800001

الإتاحة: http://hdl.handle.net/10138/572248Test

المؤلفون: Heikkinen, Anna-Leena, Tikkanen, Veera, Hänninen, Tuomo, Hublin, Christer, Koivisto, Anne M., Saari, Toni T., Remes, Anne M., Paajanen, Teemu I., Kruger, Johanna

المساهمون: Department of Neurosciences, Clinicum, Helsinki University Hospital Area, HUS Neurocenter, Faculty of Medicine

مصطلحات موضوعية: Cognitive screening, Executive functions, Mild cognitive impairment, Neurodegenerative diseases, Neuropsychological assessment, Neuropsychology, 3112 Neurosciences

وصف الملف: application/pdf

العلاقة: Heikkinen , A-L , Tikkanen , V , Hänninen , T , Hublin , C , Koivisto , A M , Saari , T T , Remes , A M , Paajanen , T I & Kruger , J 2023 , ' Utility of the INECO Frontal Screening and the Frontal Assessment Battery in detecting executive dysfunction in early-onset cognitive impairment and dementia ' , Journal of the International Neuropsychological Society . https://doi.org/10.1017/S1355617723000619Test; bae1113d-e262-4193-a3f9-a1097b9f5f63; http://hdl.handle.net/10138/571650Test; 001079321500001

الإتاحة: http://hdl.handle.net/10138/571650Test

المؤلفون: Lehtola, Juha-Matti, Kärkkäinen, Virve, Andberg, Sami, Hannonen, Sanna, Rusanen, Minna, Saari, Toni, Korhonen, Ville, Hokkanen, Laura, Hallikainen, Merja, Hänninen, Tuomo, Kaarniranta, Kai, Bednarik, Roman, Leinonen, Ville, Koivisto, Anne M.

المساهمون: Department of Psychology and Logopedics, University of Helsinki, Department of Neurosciences, Clinicum, Helsinki University Hospital Area, Neurologian yksikkö

مصطلحات موضوعية: 3112 Neurosciences, 3124 Neurology and psychiatry, 515 Psychology, Alzheimer's disease (AD), biomarker, eye tracking (ET), idiopathic normal pressure hydrocephalus (iNPH), King-Devick (KD), saccadic eye movements

وصف الملف: application/pdf

العلاقة: The authors thank all study participants, statistician Tuomas Selander and study nurses Ulla Vanhanen, Kati Mönttinen, Kristiina Holopainen, Tarja Lappalainen, and Marita Parviainen. The authors are grateful to the Juho and Lempi Pitkänen foundation, the Maire Taponen Foundation, Maud Kuistila Foundation, Finnish Cultural Foundation, Finnish Brain Foundation and Finnish Government Research Funding for financial support.; Lehtola , J-M , Kärkkäinen , V , Andberg , S , Hannonen , S , Rusanen , M , Saari , T , Korhonen , V , Hokkanen , L , Hallikainen , M , Hänninen , T , Kaarniranta , K , Bednarik , R , Leinonen , V & Koivisto , A M 2022 , ' Computer-based Eye-tracking Analysis of King-Devick Test Differentiates Persons with Idiopathic Normal Pressure Hydrocephalus from Cognitively Unimpaired ' , Alzheimer Disease and Associated Disorders , vol. 36 , no. 4 , pp. 340-346 . https://doi.org/10.1097/WAD.0000000000000527Test; ORCID: /0000-0001-8342-9248/work/129615356; ORCID: /0000-0001-7721-3336/work/130606708; 85143088755; c4b61cbd-6a88-4c59-a3c0-3cd47a10da40; http://hdl.handle.net/10138/354870Test; 000923752200010

الإتاحة: http://hdl.handle.net/10138/354870Test

المؤلفون: Saari, Toni T., Vuoksimaa, Eero

المساهمون: Institute for Molecular Medicine Finland, Clinicum, Helsinki Institute of Life Science HiLIFE, Cognitive and Brain Aging, Faculty Common Matters (Faculty of Medicine)

مصطلحات موضوعية: Cognition, Dementia, Handedness, Neurodegenerative diseases, Neuropsychiatric symptoms, 3112 Neurosciences, 3124 Neurology and psychiatry

وصف الملف: application/pdf

العلاقة: Saari , T T & Vuoksimaa , E 2023 , ' The role of hand preference in cognition and neuropsychiatric symptoms in neurodegenerative diseases ' , Brain communications , vol. 5 , no. 3 , fcad137 . https://doi.org/10.1093/braincomms/fcad137Test; ORCID: /0000-0002-6534-3667/work/139112224; ORCID: /0000-0001-7721-3336/work/139115652; 14a772ed-8e34-42ee-a035-ddfc3f89919c; http://hdl.handle.net/10138/563403Test; 001000314300003

الإتاحة: http://hdl.handle.net/10138/563403Test

المؤلفون: Hannonen, Sanna, Andberg, Sami, Kärkkäinen, Virve, Rusanen, Minna, Lehtola, Juha-Matti, Saari, Toni, Korhonen, Ville, Hokkanen, Laura, Hallikainen, Merja, Hänninen, Tuomo, Leinonen, Ville, Kaarniranta, Kai, Bednarik, Roman, Koivisto, Anne M.

المساهمون: Department of Psychology and Logopedics, University of Helsinki, Department of Neurosciences, HUS Neurocenter, Neurologian yksikkö, Geriatrian yksikkö

مصطلحات موضوعية: Alzheimer's disease, biomarker, CERAD, eye tracking, King-Devick, mild cognitive impairment, saccadic eye movements, CERAD NEUROPSYCHOLOGICAL BATTERY, KING-DEVICK TEST, ASSOCIATION WORKGROUPS, DIAGNOSTIC GUIDELINES, NATIONAL INSTITUTE, RECOMMENDATIONS, DEMENTIA, ALLELE, 3112 Neurosciences, 3124 Neurology and psychiatry, 515 Psychology, Neuropsychology

وصف الملف: application/pdf

العلاقة: We are deeply grateful to all of the study participants. We also thank BEGAD research project study nurses Ulla Vanhanen, Kati Monttinen, and Kristiina Holopainen for recruiting the study participants. We thank biostatistician Tuomas Selander for help with the statistical analysis. This work was supported by Juho and Lempi Pitkanen Foundation.; Hannonen , S , Andberg , S , Kärkkäinen , V , Rusanen , M , Lehtola , J-M , Saari , T , Korhonen , V , Hokkanen , L , Hallikainen , M , Hänninen , T , Leinonen , V , Kaarniranta , K , Bednarik , R & Koivisto , A M 2022 , ' Shortening of Saccades as a Possible Easy-to-Use Biomarker to Detect Risk of Alzheimer's Disease ' , Journal of Alzheimer's Disease , vol. 88 , no. 2 , pp. 609-618 . https://doi.org/10.3233/JAD-215551Test; ORCID: /0000-0001-8342-9248/work/117173311; cf23b6b3-9995-43a9-a640-5ab028bd110c; http://hdl.handle.net/10138/346799Test; 000828034300020

الإتاحة: http://hdl.handle.net/10138/346799Test

المؤلفون: Lampinen, Riikka, Fazaludeen, Mohammad Feroze, Avesani, Simone, Ord, Tiit, Penttila, Elina, Lehtola, Juha-Matti, Saari, Toni, Hannonen, Sanna, Saveleva, Liudmila, Kaartinen, Emma, Fernandez Acosta, Francisco, Cruz-Haces, Marcela, Lopponen, Heikki, Mackay-Sim, Alan, Kaikkonen, Minna U., Koivisto, Anne M., Malm, Tarja, White, Anthony R., Giugno, Rosalba, Chew, Sweelin, Kanninen, Katja M.

المساهمون: Department of Neurosciences, Neurologian yksikkö, HUS Neurocenter, Geriatrian yksikkö

مصطلحات موضوعية: Alzheimer's disease, olfactory mucosa, amyloid beta, single-cell RNA-sequencing, mitochondria, BETA, EXPRESSION, BRAIN, TAU, NEUROGENESIS, DYSFUNCTION, CONSORTIUM, EPITHELIUM, ESTABLISH, REGISTRY, 3112 Neurosciences, 3124 Neurology and psychiatry, 1182 Biochemistry, cell and molecular biology

وصف الملف: application/pdf

العلاقة: This research was funded by The Academy of Finland (295425), The Sigrid Juselius Foundation, The Finnish Cultural Foundation, The Inkeri and Mauri Vanska Foundation, The Yrjo Jahnsson Foundation, The Saastamoinen Foundation and The Finnish Brain Foundation. This project has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement No 814978.; Lampinen , R , Fazaludeen , M F , Avesani , S , Ord , T , Penttila , E , Lehtola , J-M , Saari , T , Hannonen , S , Saveleva , L , Kaartinen , E , Fernandez Acosta , F , Cruz-Haces , M , Lopponen , H , Mackay-Sim , A , Kaikkonen , M U , Koivisto , A M , Malm , T , White , A R , Giugno , R , Chew , S & Kanninen , K M 2022 , ' Single-Cell RNA-Seq Analysis of Olfactory Mucosal Cells of Alzheimer's Disease Patients ' , Cells , vol. 11 , no. 4 , 676 . https://doi.org/10.3390/cells11040676Test; 9418c0ce-00e1-44de-8e9b-67d358dc255d; http://hdl.handle.net/10138/342420Test; 000763939800001

الإتاحة: http://hdl.handle.net/10138/342420Test

المؤلفون: Lampinen, Riikka, Gorova, Veronika, Avesani, Simone, Liddell, Jeffrey R., Penttilä, Elina, Zavodna, Tana, Krejcik, Zdenek, Lehtola, Juha-Matti, Saari, Toni, Kalapudas, Juho, Hannonen, Sanna, Lopponen, Heikki, Topinka, Jan, Koivisto, Anne M., White, Anthony R., Giugno, Rosalba, Kanninen, Katja M.

المساهمون: Department of Neurosciences, University of Helsinki, Neurologian yksikkö, HUS Internal Medicine and Rehabilitation, HUS Neurocenter, Faculty of Medicine, Geriatrian yksikkö

مصطلحات موضوعية: calcium, olfactory mucosa cells, DEMENTIA, zinc, 3112 Neurosciences, ASSOCIATION, Alzheimer's disease, GUIDELINES, GENE, olfactory dysfunction, PROTEOME, Trace Elements, ALPHA(2)-MACROGLOBULIN, MACROGLOBULIN, biometals, Olfactory Mucosa, Alzheimer Disease, 1182 Biochemistry, cell and molecular biology, Humans, BETA-AMYLOID PEPTIDE, Alzheimer’s disease, sodium, alpha-2-macroglobulin, Chelating Agents

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6cb63a3d8d1b3184a2b0e82d68cc62f3Test
http://hdl.handle.net/11562/1062795Test

المؤلفون: Saari, Toni, Koivisto, Anne, Hintsa, Taina, Hänninen, Tuomo, Hallikainen, Ilona

المساهمون: Department of Neurosciences, University of Helsinki, HUS Internal Medicine and Rehabilitation, Geriatrian yksikkö, Department of Medicine

مصطلحات موضوعية: validity, reliability, SYMPTOMS, BEHAVIORAL-DISORDERS, DEMENTIA, Neuropsychiatric Inventory, PSYCHOPATHOLOGY, 3112 Neurosciences, Alzheimer's disease, CONSTRUCT-VALIDATION, behavioral and psychological symptoms of dementia, humanities, 3124 Neurology and psychiatry, ALZHEIMERS-DISEASE, mental disorders, neuropsychiatric symptoms, measurement, CHINESE VERSION, NPI

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=od______1593::0af3eb122841f9675cec40191207ee88Test
http://hdl.handle.net/10138/343421Test