المؤلفون: Aleix Bayona-Feliu, Sonia Barroso, Andrés Aguilera, Sergio Muñoz

المساهمون: European Research Council, Ministerio de Economía y Competitividad (España), Ministerio de Ciencia, Innovación y Universidades (España), Agencia Estatal de Investigación (España), Universidad de Sevilla. Departamento de Genética

المصدر: Nature Genetics
Digital.CSIC. Repositorio Institucional del CSIC
instname
idUS. Depósito de Investigación de la Universidad de Sevilla

مصطلحات موضوعية: Genome instability, DNA Replication, Transcription, Genetic, R-loop, Chromosomal Proteins, Non-Histone, genetic processes, Tumor suppressors, macromolecular substances, Biology, Chromatin remodeling, Genomic Instability, 03 medical and health sciences, 0302 clinical medicine, BRG1, Transcription (biology), Chromatin remodelers, Genetics, Transcription-replication conflicts, Humans, 030304 developmental biology, Adenosine Triphosphatases, 0303 health sciences, Fanconi Anemia Complementation Group D2 Protein, DNA replication, R-loops, Chromatin Assembly and Disassembly, cBAF, SWI/SNF, Chromatin, 3. Good health, Cell biology, enzymes and coenzymes (carbohydrates), Fanconi Anemia, Genetic Loci, SMARCA4, health occupations, biological phenomena, cell phenomena, and immunity, R-Loop Structures, 030217 neurology & neurosurgery, Transcription Factors

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::000e7eb4558af3f6898dc7eb4afec9acTest
https://hdl.handle.net/10668/17790Test

المؤلفون: Sylvain Martineau, Andrés Aguilera, Damarys Loew, Gaetana Sessa, Charlotte Martin, Belén Gómez-González, Sonia Barroso, Juan S Martinez, Åsa Ehlén, Sonia Silva, Bérangère Lombard, Aura Carreira, Stephan Vagner, Carmen Pérez-Calero, Romane Beaurepere

المساهمون: Agence Nationale de la Recherche (France), Institut National du Cancer (France), Ligue Nationale contre le Cancer (France), European Research Council, Ministerio de Economía y Competitividad (España), Fundación Vencer el Cancer, European Commission, Institut Curie, Centre National de la Recherche Scientifique (France), Fondation ARC pour la Recherche sur le Cancer, Ministére de l'Education Nationale de la Recherche et de la Technologie (France), Asociación Española Contra el Cáncer, Ministerio de Economía, Industria y Competitividad (España), Fondation de France, Universidad de Sevilla. Departamento de Genética, Intégrité du génome, ARN et cancer, Institut Curie [Paris]-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Andalusian Molecular Biology and Regenerative Medicine Centre (CABIMER)

المصدر: Digital.CSIC. Repositorio Institucional del CSIC
instname
idUS. Depósito de Investigación de la Universidad de Sevilla
EMBO Journal
EMBO Journal, EMBO Press, 2021, 40 (7), pp.e106018. ⟨10.15252/embj.2020106018⟩
idUS: Depósito de Investigación de la Universidad de Sevilla
Universidad de Sevilla (US)
The EMBO Journal
EMBO J

مصطلحات موضوعية: Genome instability, endocrine system diseases, [SDV]Life Sciences [q-bio], RAD51, homologous recombination, General Biochemistry, Genetics and Molecular Biology, law.invention, DEAD-box RNA Helicases, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, DNA-RNA hybrids, law, Cell Line, Tumor, Humans, DNA double-strand breaks, A-DNA, DNA Breaks, Double-Stranded, Homologous recombination, skin and connective tissue diseases, Molecular Biology, neoplasms, 030304 developmental biology, BRCA2 Protein, 0303 health sciences, General Immunology and Microbiology, DDX5, biology, General Neuroscience, Nucleic Acid Heteroduplexes, Helicase, Recombinational DNA Repair, Articles, R-loops, RNA Helicase A, BRCA2, female genital diseases and pregnancy complications, 3. Good health, Cell biology, HEK293 Cells, chemistry, biology.protein, Suppressor, 030217 neurology & neurosurgery, Protein Binding

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66fa45e56f043cfb351bb29e4dbe866fTest
http://hdl.handle.net/10261/259110Test

المؤلفون: Florian J. Groelly, Emilia Puig Lombardi, Rebecca A. Dagg, Gijs Zonderland, Thanos D. Halazonetis, Benjamin Wright, Eliana M.C. Tacconi, Giacomo G. Rossetti, Sonia Barroso, Madalena Tarsounas, Helen Lockstone, Andrés Aguilera

المساهمون: European Research Council, Swiss National Science Foundation, European Commission, Cancer Research UK, University of Oxford, EMBO, Universidad de Sevilla. Departamento de Genética

المصدر: Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Communications
idUS. Depósito de Investigación de la Universidad de Sevilla
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)

مصطلحات موضوعية: Cyclin-Dependent Kinase Inhibitor p21, Cell biology, Transcription, Genetic, endocrine system diseases, Cell Survival, DNA damage, Science, General Physics and Astronomy, Breast Neoplasms, DNA replication, Biology, Article, General Biochemistry, Genetics and Molecular Biology, Transcriptome, 03 medical and health sciences, 0302 clinical medicine, Germline mutation, Downregulation and upregulation, Cell Line, Tumor, Humans, RNA-Seq, skin and connective tissue diseases, Cells, Cultured, beta Catenin, Cancer, Cell Proliferation, 030304 developmental biology, BRCA2 Protein, Ovarian Neoplasms, 0303 health sciences, Multidisciplinary, Oncogene, BRCA1 Protein, Gene Expression Profiling, Oncogenes, General Chemistry, 3. Good health, 030220 oncology & carcinogenesis, Catenin, Cancer cell, Female, CDK inhibitor, DNA Damage, HeLa Cells

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cdfd74eb2978ae343548a465b4255aeTest
http://hdl.handle.net/10261/259102Test

المؤلفون: Andrés Aguilera, Sonia Barroso

المساهمون: Ministerio de Economía y Competitividad (España), Junta de Andalucía, European Research Council, European Commission

المصدر: Homologous Recombination-Methods and Protocols
Homologous Recombination ISBN: 9781071606438
Digital.CSIC. Repositorio Institucional del CSIC
instname
Methods in Molecular Biology
Methods in Molecular Biology-Homologous Recombination

مصطلحات موضوعية: 0301 basic medicine, Gene isoform, Double-strand breaks, DNA repair, DNA damage, cells, Immunofluorescence, Immunoblotting, medicine.disease_cause, Genome, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Histone H2A, medicine, biology, fungi, 3. Good health, Cell biology, enzymes and coenzymes (carbohydrates), 030104 developmental biology, Histone, chemistry, γ-H2AX, 030220 oncology & carcinogenesis, biology.protein, biological phenomena, cell phenomena, and immunity, Carcinogenesis, DNA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3310854d6e40148091dfe840365a0603Test

المؤلفون: Silvia Jimeno-González, Rosario Prados-Carvajal, Pablo Huertas, Guillermo Rodríguez-Real, Martín Endara-Coll, Sonia Barroso, Amador Romero-Franco, Domenico Alessandro Silvestris, Judit Domingo-Prim, Fernando Mejías-Navarro, María Jesús Fernández-Ávila, Sonia Jimeno, Neus Visa, Andrés Aguilera, Valeriana Cesarini, Angela Gallo, Sonia Silva

المساهمون: Agencia Estatal de Investigación (España), Ministerio de Ciencia, Innovación y Universidades (España), Ministerio de Economía y Competitividad (España), European Research Council, Associazione Italiana per la Ricerca sul Cancro, Swedish Research Council, Swedish Cancer Society, European Commission, Stockholm University, EMBO, Junta de Andalucía, Universidad de Sevilla. Departamento de Genética, Agencia Estatal de Investigación. España PID2019-104195GB-I00, AEI/10.13039/501100011033

المصدر: Nature Communications
Nature communications (2021).
info:cnr-pdr/source/autori:Sonia Jimeno # 1 2, Rosario Prados-Carvajal # 3 4, María Jesús Fernández-Ávila 4, Sonia Silva 3 4, Domenico Alessandro Silvestris 5, Martín Endara-Coll 6, Guillermo Rodríguez-Real 3 4, Judit Domingo-Prim 6 7, Fernando Mejías-Navarro 3 4, Amador Romero-Franco 3 4, Silvia Jimeno-González 3 4, Sonia Barroso 3 4, Valeriana Cesarini 5, Andrés Aguilera 3 4, Angela Gallo 5, Neus Visa 6, Pablo Huertas 8 9/titolo:ADAR-mediated RNA editing of DNA:RNA hybrids is required for DNA double strand break repair./doi:/rivista:Nature communications/anno:2021/pagina_da:/pagina_a:/intervallo_pagine:/volume
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
idUS. Depósito de Investigación de la Universidad de Sevilla

مصطلحات موضوعية: RNA editing, DNA Repair, DNA repair, DNA damage, Adenosine Deaminase, Science, Green Fluorescent Proteins, General Physics and Astronomy, General Biochemistry, Genetics and Molecular Biology, Genomic Instability, Article, 03 medical and health sciences, Nucleic acid thermodynamics, chemistry.chemical_compound, 0302 clinical medicine, Genes, Reporter, Cell Line, Tumor, Replication Protein A, Humans, DNA Breaks, Double-Stranded, Homologous recombination, Gene, 030304 developmental biology, 0303 health sciences, Multidisciplinary, BRCA1 Protein, Protein Stability, DNA Helicases, RNA, Nucleic Acid Hybridization, RNA-Binding Proteins, General Chemistry, DNA, ADAR, Multifunctional Enzymes, 3. Good health, Cell biology, chemistry, DNA double strand break repair, 030220 oncology & carcinogenesis, Gene Deletion, RNA Helicases

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f075a61e84919438cead025b6b33d08Test
https://pubmed.ncbi.nlm.nih.gov/34535666Test

المؤلفون: Marta Gianini, Cristina Cereda, Daisy Sproviero, Sonia Barroso, Aleix Bayona-Feliu, Andrés Aguilera

المساهمون: Fondazione Regionale per la Ricerca Biomedica, European Research Council, European Commission, Ministerio de Economía y Competitividad (España), Ministerio de Ciencia, Innovación y Universidades (España), Agencia Estatal de Investigación (España), Universidad de Sevilla. Departamento de Genética

المصدر: Digital.CSIC. Repositorio Institucional del CSIC
instname
idUS: Depósito de Investigación de la Universidad de Sevilla
Universidad de Sevilla (US)
PLoS Genetics, Vol 16, Iss 12, p e1009260 (2020)
idUS. Depósito de Investigación de la Universidad de Sevilla
PLoS Genetics
PLOS Genetics

مصطلحات موضوعية: Genome instability, Male, Cancer Research, R-loop, Cultured tumor cells, Gene Expression, RNA-binding protein, QH426-470, Biochemistry, Motor Neuron Diseases, Mice, 0302 clinical medicine, Medical Conditions, Fanconi anemia, Gene expression, Medicine and Health Sciences, Homeostasis, DNA Breaks, Double-Stranded, Amyotrophic lateral sclerosis, Genetics (clinical), Cells, Cultured, 0303 health sciences, Cytoplasmic Inclusions, Neurodegenerative Diseases, Transfection, Genomics, Middle Aged, 3. Good health, Cell biology, Precipitation Techniques, Nucleic acids, DNA-Binding Proteins, Neurology, Cell lines, Biological cultures, Research Article, DNA damage, Biology, Genomic Instability, 03 medical and health sciences, mental disorders, medicine, Genetics, Immunoprecipitation, Animals, Humans, HeLa cells, Molecular Biology Techniques, Molecular Biology, Ecology, Evolution, Behavior and Systematics, 030304 developmental biology, Amyotrophic Lateral Sclerosis, Biology and Life Sciences, nutritional and metabolic diseases, DNA, Cell Biology, medicine.disease, Cell cultures, nervous system diseases, Research and analysis methods, Mutation, R-Loop Structures, 030217 neurology & neurosurgery, HeLa Cells

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d56a3bc7ce25d270d96e04a02703bceTest
http://hdl.handle.net/10261/228270Test

المؤلفون: Andrés Aguilera, Xiaoyu Xue, Patrick Sung, Víctor M. González-Basallote, Sonia Barroso, Sergio Muñoz, Carmen Pérez-Calero, Aleix Bayona-Feliu

المساهمون: Universidad de Sevilla. Departamento de Genética

المصدر: Digital.CSIC. Repositorio Institucional del CSIC
instname
idUS: Depósito de Investigación de la Universidad de Sevilla
Universidad de Sevilla (US)
Genes & Development
idUS. Depósito de Investigación de la Universidad de Sevilla

مصطلحات موضوعية: Genome instability, Double-strand breaks, UAP56/DDX39B, THO complex, R loops, Biology, RNA–DNA helicase, Genome, 03 medical and health sciences, 0302 clinical medicine, Transcription (biology), Replication fork stalling, Genetics, RNA–DNA hybrids, 030304 developmental biology, 0303 health sciences, Helicase, RNA, 3. Good health, Chromatin, Cell biology, Histone, 030220 oncology & carcinogenesis, biology.protein, Developmental Biology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f3d1a204dd8d2891ce8fa756e1bc63bTest
http://hdl.handle.net/10261/221299Test

المؤلفون: Andrés Aguilera, Emilia Herrera-Moyano, Belén Gómez-González, Sonia Barroso

المساهمون: Universidad de Sevilla. Departamento de Genética, European Commission, European Research Council, Asociación Española Contra el Cáncer, Worldwide Cancer Research, Gómez-González, Belén [0000-0003-1655-8407], Barroso, Sonia [0000-0002-0062-2016], Herrera-Moyano, Emilia [0000-0003-3948-3874], Aguilera, Andrés [0000-0003-4782-1714], Gómez-González, Belén, Barroso, Sonia, Herrera-Moyano, Emilia, Aguilera, Andrés

المصدر: Digital.CSIC. Repositorio Institucional del CSIC
instname
Cell Cycle
idUS. Depósito de Investigación de la Universidad de Sevilla
idUS: Depósito de Investigación de la Universidad de Sevilla
Universidad de Sevilla (US)

مصطلحات موضوعية: 0301 basic medicine, Genome instability, DNA Replication, Postreplication repair, DNA Repair, DNA damage, Genetic instability, DNA, Single-Stranded, Review, Ataxia Telangiectasia Mutated Proteins, Biology, DNA damage response, 03 medical and health sciences, 0302 clinical medicine, DNA-RNA hybrids, Transcription (biology), Animals, Humans, Molecular Biology, Base Pairing, Cell Cycle, Cell Biology, Cell cycle, Replicative stress, 3. Good health, Cell biology, 030104 developmental biology, 030220 oncology & carcinogenesis, Checkpoint Kinase 1, RNA, Dna rna hybrids, Developmental Biology, DNA Damage

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b65372c1c2f16835b98e23b2a0634b93Test

المؤلفون: Carlos M. Galmarini, Marta San Martin-Alonso, Sonia Barroso, Emanuela Tumini, Emilia Herrera-Moyano, Andrés Aguilera

المساهمون: Universidad de Sevilla. Departamento de Genética, European Research Council, Ministerio de Economía y Competitividad (España), European Commission, PharmaMar

المصدر: idUS: Depósito de Investigación de la Universidad de Sevilla
Universidad de Sevilla (US)
Molecular Cancer Research
Digital.CSIC. Repositorio Institucional del CSIC
instname
idUS. Depósito de Investigación de la Universidad de Sevilla

مصطلحات موضوعية: 0301 basic medicine, Genome instability, DNA Replication, Lurbinectedin, Cancer Research, DNA damage, RAD52, Biology, Heterocyclic Compounds, 4 or More Rings, Article, Genomic Instability, 03 medical and health sciences, 0302 clinical medicine, Transcription (biology), FANCD2, medicine, Humans, Molecular Biology, Trabectedin, Cell Proliferation, Cancer, Cell growth, R-loops, 3. Good health, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, Cancer cell, Cancer research, medicine.drug, Carbolines, HeLa Cells

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3093e51e83f9c9b4ef61d2a3aebcc1cfTest

المؤلفون: Belén Gómez-González, María L. García-Rubio, Emilia Herrera-Moyano, Sergio Muñoz, Andrés Aguilera, Sonia Barroso

المساهمون: European Research Council, Worldwide Cancer Research, World Cancer Research Fund International, Fundación Científica Asociación Española Contra el Cáncer, Universidad de Sevilla. Departamento de Genética

المصدر: EMBO reports
idUS. Depósito de Investigación de la Universidad de Sevilla
instname
Digital.CSIC. Repositorio Institucional del CSIC
EMBO Rep

مصطلحات موضوعية: DNA Replication, R loop, Small interfering RNA, DNA damage, R-loop, DNA, Single-Stranded, Biology, Real-Time Polymerase Chain Reaction, DNA damage response, Models, Biological, Biochemistry, 03 medical and health sciences, 0302 clinical medicine, Dna dynamics, Genetics, Humans, Discoidin Domain Receptors, Molecular Biology, Gene, 030304 developmental biology, 0303 health sciences, Phosphoric Diester Hydrolases, Cell Cycle, Articles, G2-M DNA damage checkpoint, Flow Cytometry, post-replicative repair, 3. Good health, Chromatin, Cell biology, DNA-Binding Proteins, ATR, ATM, Ubiquitin-Conjugating Enzymes, Dna rna hybrids, 030217 neurology & neurosurgery, DNA Damage, HeLa Cells, Signal Transduction

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ccbb0847a5aef4c28cb38e8e488e0a6Test