المؤلفون: Nauder Faraday, Brian D. Hobbs, Quan Sun, Michael Preuss, Ani Manichaikul, Eric Jorgenson, Ming-Huei Chen, Eric Boerwinkle, Florian Thibord, Arunoday Bhan, Alanna C. Morrison, Ramachandran S. Vasan, Nathan Pankratz, Charles Kooperberg, Deborah A. Nickerson, Joshua P. Lewis, Hélène Choquet, Jee-Young Moon, Jeffrey R. O'Connell, Marsha M. Wheeler, Albert V. Smith, Russell P. Tracy, Nathalie Chami, Ruth J. F. Loos, Alexander P. Reiner, Nicholas L. Smith, Gonçalo R. Abecasis, Laura M. Raffield, Amarise Little, Nancy L. Heard-Costa, Andrew D. Johnson, David C. Glahn, Rasika A. Mathias, Adam S. Butterworth, John Blangero, Joanne E. Curran, Timothy A. Thornton, Laura Almasy, Jerome I. Rotter, Nancy Min, Lisa R. Yanek, Donald M. Lloyd-Jones, Zhe Wang, Matthew P. Conomos, Myriam Fornage, Hua Tang, Lewis C. Becker, Lynette Ekunwe, Cecelia A. Laurie, Adolfo Correa, Jai G. Broome, Terri H. Beaty, Jennifer A. Brody, Caitlin P. McHugh, Yao Hu, Braxton D. Mitchell, Lifang Hou, Yun Li, Kathleen A. Ryan, Paul L. Auer, Stephen S. Rich, Kari E. North, Thomas W. Blackwell, Bruce M. Psaty, Deepti Jain, Paul S Vries, Praveen Surendran

المساهمون: Butterworth, Adam [0000-0002-6915-9015], Apollo - University of Cambridge Repository

المصدر: Human molecular genetics, vol 31, iss 3
Hum Mol Genet

مصطلحات موضوعية: Blood Platelets, Platelet disorder, Population, Genome-wide association study, Biology, Quantitative trait locus, Polymorphism, Single Nucleotide, Medical and Health Sciences, Genome, 03 medical and health sciences, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, 0302 clinical medicine, Clinical Research, and Blood Institute (U.S.), Genetics, Humans, 2.1 Biological and endogenous factors, Polymorphism, Precision Medicine, Aetiology, Mean platelet volume, education, Hemostatic function, Lung, Molecular Biology, Genetics (clinical), 030304 developmental biology, Blood Platelet Disorders, Genetics & Heredity, 0303 health sciences, education.field_of_study, Human Genome, Single Nucleotide, National Heart, Hematology, General Medicine, Biological Sciences, United States, 3. Good health, Phenotype, Good Health and Well Being, 030220 oncology & carcinogenesis, General Article, National Heart, Lung, and Blood Institute (U.S.), Genome-Wide Association Study, Biotechnology

وصف الملف: application/pdf; application/octet-stream

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fc9557e325812482460ef4586ad1a77Test
https://doi.org/10.1093/hmg/ddab252Test

المؤلفون: Yoav Ben-Shlomo, Ming-Huei Chen, Peter Creighton Elwood, Arunoday Bhan, Mete Civelek, FinnGen Study, David-Alexandre Trégouët, Veikko Salomaa, Benjamin Rodriguez, Teemu J. Niiranen, Thorsten M. Schlaeger, Andrew D. Johnson, Andrew D Beswick, Pierre-Emmanuel Morange

المساهمون: Bordeaux population health (BPH), Université de Bordeaux (UB)-Institut de Santé Publique, d'Épidémiologie et de Développement (ISPED)-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre recherche en CardioVasculaire et Nutrition = Center for CardioVascular and Nutrition research (C2VN), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)

المصدر: American Journal of Human Genetics
American Journal of Human Genetics, Elsevier (Cell Press), In press, 107 (2), pp.211-221. ⟨10.1016/j.ajhg.2020.06.008⟩
American Journal of Human Genetics, In press, 107 (2), pp.211-221. ⟨10.1016/j.ajhg.2020.06.008⟩
Am J Hum Genet
Rodriguez, B A T, Bhan, A, Beswick, A, Elwood, P C, Niiranen, T J, Salomaa, V, Trégouët, D-A, Morange, P-E, Civelek, M, Ben-Shlomo, Y, Schlaeger, T, Chen, M-H & Johnson, A D 2020, ' A Platelet Function Modulator of Thrombin Activation Is Causally Linked to Cardiovascular Disease and Affects PAR4 Receptor Signaling ', American Journal of Human Genetics . https://doi.org/10.1016/j.ajhg.2020.06.008Test

مصطلحات موضوعية: 0301 basic medicine, Male, Platelet Aggregation, Embolism, Genome-wide association study, 030204 cardiovascular system & hematology, Pharmacology, 0302 clinical medicine, Megakaryocyte, Cardiovascular Disease, Neoplasms, Medicine, Platelet, Receptor, Lung, Genetics (clinical), Thrombin, Middle Aged, thrombin, stroke, 3. Good health, Stroke, medicine.anatomical_structure, VINTAGE, Cardiovascular Diseases, Female, medicine.drug, Signal Transduction, Platelets, Blood Platelets, venous thromboembolism, eQTL, GWA, Article, 03 medical and health sciences, Downregulation and upregulation, Mendelian randomization, Genetics, Humans, Receptor, PAR-1, Platelet activation, thrombosis, Alleles, Heart Failure, business.industry, Platelet Activation, 030104 developmental biology, Receptors, Thrombin, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, business, Genome-Wide Association Study

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ed6f4d72d2a9d16e1e20ed0efb7eff0Test
https://hal.archives-ouvertes.fr/hal-03141739Test

المؤلفون: Jeffrey R. O'Connell, L. Adrienne Cupples, Alan R. Shuldiner, Braxton D. Mitchell, Ali R. Keramati, Lisa R. Yanek, Lewis C. Becker, Brady Gaynor, Kanika Kanchan, Achilleas N. Pitsillides, Joshua P. Lewis, Ming-Huei Chen, Kai Kammers, Nauder Faraday, Rasika A. Mathias, Kruthika R. Iyer, Madeline H. Kowalski, Benjamin Rodriguez, Jennifer A. Brody, Margaret A. Taub, Andrew D. Johnson, Nhlbi TOPMed Hematology, Kathleen A. Ryan

مصطلحات موضوعية: Whole genome sequencing, 0303 health sciences, Regulator, Locus (genetics), Computational biology, 030204 cardiovascular system & hematology, Biology, DNA sequencing, 3. Good health, 03 medical and health sciences, 0302 clinical medicine, Super-enhancer, Expression quantitative trait loci, Epigenetics, Gene, 030304 developmental biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdbdd69b3c5101017553fd77f51d3b3fTest

المؤلفون: Robert Kraaij, Teresa Nutile, Peter Vollenweider, Cassianne Robinson-Cohen, Caroline S. Fox, André G. Uitterlinden, Sanaz Sedaghat, Cornelia M. van Duijn, Alanna C. Morrison, Meng Li, Bing Yu, Sahar Ghasemi, Zoltán Kutalik, Eric Boerwinkle, Alexanda Teumer, Jeroen van Rooij, Qiong Yang, Audrey Y. Chu, Jennifer E. Huffman, Bruce M. Psaty, Jun Liu, Najaf Amin, Jennifer A. Brody, Adrienne Tin, Rossella Sorice, Ming-Huei Chen, Marina Ciullo, Anna Köttgen, Yong Li, Ayse Demirkan, Owen M. Woodward, Melody Swen, Abbas Dehghan, Aurélien Macé, Barbara McKnight

المساهمون: Epidemiology, Internal Medicine

المصدر: Nature Communications
Nature communications 9 (2018). doi:10.1038/s41467-018-06620-4
info:cnr-pdr/source/autori:Tin A.; Li Y.; Brody J.A.; Nutile T.; Chu A.Y.; Huffman J.E.; Yang Q.; Chen M.-H.; Robinson-Cohen C.; Mace A.; Liu J.; Demirkan A.; Sorice R.; Sedaghat S.; Swen M.; Yu B.; Ghasemi S.; Teumer A.; Vollenweider P.; Ciullo M.; Li M.; Uitterlinden A.G.; Kraaij R.; Amin N.; van Rooij J.; Kutalik Z.; Dehghan A.; McKnight B.; van Duijn C.M.; Morrison A.; Psaty B.M.; Boerwinkle E.; Fox C.S.; Woodward O.M.; Kottgen A./titolo:Large-scale whole-exome sequencing association studies identify rare functional variants influencing serum urate levels/doi:10.1038%2Fs41467-018-06620-4/rivista:Nature communications/anno:2018/pagina_da:/pagina_a:/intervallo_pagine:/volume:9
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Nature Communications, 9:4228. Nature Publishing Group
Nature communications, vol. 9, no. 1, pp. 4228

مصطلحات موضوعية: 0301 basic medicine, Organic Cation Transport Proteins, Science, Glucose Transport Proteins, Facilitative, General Physics and Astronomy, Organic Anion Transporters, Genome-wide association study, Disease, Bioinformatics, Kidney Function Tests, General Biochemistry, Genetics and Molecular Biology, Article, Protein Structure, Secondary, 03 medical and health sciences, chemistry.chemical_compound, Exome/genetics, Genetic Predisposition to Disease, Glucose Transport Proteins, Facilitative/chemistry, Glucose Transport Proteins, Facilitative/genetics, Glucose Transport Proteins, Facilitative/metabolism, Humans, Meta-Analysis as Topic, Organic Anion Transporters/chemistry, Organic Anion Transporters/genetics, Organic Anion Transporters/metabolism, Organic Cation Transport Proteins/chemistry, Organic Cation Transport Proteins/genetics, Organic Cation Transport Proteins/metabolism, Uric Acid/blood, MD Multidisciplinary, medicine, Exome, lcsh:Science, Exome sequencing, Genetic association, Multidisciplinary, biology, business.industry, Lesinurad, serum urate levels, General Chemistry, medicine.disease, 3. Good health, Gout, Uric Acid, 030104 developmental biology, chemistry, biology.protein, SLC22A12, lcsh:Q, business, SLC2A9

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09617704df3edc2b2becb350d2b1af49Test
https://doi.org/10.1038/s41467-018-06620-4Test

المؤلفون: Mary Cushman, John M. Starr, Min-Lee Yang, Wei Zhou, Ursula M. Schick, Vinna Clavo, Bella Hu, Oluf Pedersen, Tarunveer S. Ahluwalia, John D. Eicher, Santhi K. Ganesh, Albert V. Smith, Abbas Dehghan, Rebecca D. Jackson, Ian J. Deary, Mika Kähönen, Megan L. Grove, Jennifer A. Brody, Judy Wang, Amanda M Rosa Di Sant, Lenore J. Launer, Stephen S. Rich, Jiansong Wang, David C. Liewald, Paul I.W. de Bakker, Jerome I. Rotter, Leo-Pekka Lyytikäinen, Ruth J. F. Loos, Leonard I. Zon, Bruce M. Psaty, Nora Franceschini, Erwin P. Bottinger, Ming-Huei Chen, Paul L. Auer, James G. Wilson, Raha Pazoki, Nathan Pankratz, Russell P. Tracy, Vilmundur Gudnason, André G. Uitterlinden, Mike A. Nalls, Kristina L. Hunker, Frank J. A. van Rooij, Eric Boerwinkle, Kent D. Taylor, Albert Hofman, Yan Zhang, Mattijs E. Numans, Yong Huo, Yi Zhou, Folkert W. Asselbergs, James S. Floyd, Richard L. Proia, Yingchang Lu, Terho Lehtimäki, Liguang Dong, Riccardo E. Marioni, Jette Bork-Jensen, Jia Jia, Tamara B. Harris, Vy M. Nguyen, Fernando Rivadeneira, Oscar H. Franco, Yongmei Liu, Niels Grarup, Andrew D. Johnson, L. Adrienne Cupples, Ani Manichaikul, Elliott J. Hagedorn, Xiaoling Zhang, Maarten Leusink, Torben Hansen, Ingrid B. Borecki, Maria L. Allende, Betina Heinsbek Thuesen, Allan Linneberg, Olli T. Raitakari, Christopher J. O'Donnell, Mary F. Feitosa, Melissa E. Garcia, Alexander P. Reiner

المساهمون: Epidemiology, Internal Medicine

المصدر: Nature genetics
Pankratz, N, Schick, U M, Zhou, Y, Zhou, W, Ahluwalia, T S, Allende, M L, Auer, P L, Bork-Jensen, J, Brody, J A, Chen, M H, Clavo, V, Eicher, J D, Grarup, N, Hagedorn, E J, Hu, B, Hunker, K, Johnson, A D, Leusink, M, Lu, Y, Lyytikainen, L P, Manichaikul, A, Marioni, R, Nalls, M A, Pazoki, R, Smith, A V, Van Rooij, F J A, Yang, M L, Zhang, X, Zhang, Y, Asselbergs, F W, Boerwinkle, E, Borecki, I B, Bottinger, E P, Cushman, M, De Bakker, P I W, Deary, I, Dong, L, Feitosa, M F, Floyd, J S, Franceschini, N, Franco, O H, Garcia, M E, Grove, M L, Gudnason, V, Hansen, T, Harris, T B, Hofman, A, Jackson, R D, Jia, J, Kahonen, M, Launer, L J, Lehtimaki, T, Liewald, D, Linneberg, A, Liu, Y, Loos, R J F, Nguyen, V M, Numans, M E, Pedersen, O, Psaty, B M, Raitakari, O T, Rich, S S, Rivadeneira, F, Di Sant, A M R, Rotter, J I, Starr, J, Taylor, K D, Thuesen, B H, Tracy, R P, Uitterlinden, A G, Wang, J, Wang, J, Dehghan, A, Huo, Y, Adrienne Cupples, L, Wilson, J G, Proia, R L, Zon, L I, O'Donnell, C J, Reiner, A P & Ganesh, S K 2016, ' Meta-analysis of rare and common exome chip variants identifies S1PR4 and other loci influencing blood cell traits ', Nature Genetics, vol. 48, no. 8, pp. 867-876 . https://doi.org/10.1038/ng.3607Test
Nature Genetics, 48(8), 867. Nature Publishing Group
Nature Genetics, 48(8), 867-876. Nature Publishing Group
Nature Genetics, 48(8), 867

مصطلحات موضوعية: Male, 0301 basic medicine, Erythrocytes, Quantitative Trait Loci, Population, Genome-wide association study, Quantitative trait locus, Hematocrit, Biology, Article, Mice, 03 medical and health sciences, White blood cell, Genotype, Ethnicity, Journal Article, Genetics, medicine, Animals, Humans, Exome, education, Zebrafish, Medicine(all), education.field_of_study, medicine.diagnostic_test, ta1184, ta3121, 3. Good health, Receptors, Lysosphingolipid, 030104 developmental biology, medicine.anatomical_structure, Genetic Loci, Immunology, Erythrocyte Count, Absolute neutrophil count, Female, Genome-Wide Association Study

وصف الملف: image/pdf; application/vnd.openxmlformats-officedocument.wordprocessingml.document

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aecb861e80d29ff2a272e87236da408Test
https://doi.org/10.1038/ng.3607Test

المؤلفون: Raha Pazoki, Nora Franceschini, James S. Floyd, Guillaume Lettre, Fernando Rivadeneira, Abbas Dehghan, Leo-Pekka Lyytikäinen, Albert Hofman, Ming-Huei Chen, Eric Boerwinkle, Jill M. Johnsen, Mart Kals, Xiaoling Zhang, Lewis C. Becker, Jennifer A. Brody, Dennis O. Mook-Kanamori, Lu Chen, James G. Wilson, Rajiv K. Khajuria, Vijay G. Sankaran, Nathan Pankratz, Lisa R. Yanek, Leslie A. Lange, Mika Kähönen, Linda M. Polfus, Traci M. Bartz, Nena Matijevic, Oscar H. Franco, Donna M. Muzny, Keolu Fox, Richard A. Gibbs, Narayanan Veeraraghavan, Tõnu Esko, Aoi Wakabayashi, Gina M. Peloso, André G. Uitterlinden, Paul L. Auer, Frank J. A. van Rooij, Kenneth Rice, Santhi K. Ganesh, Terho Lehtimäki, Klaudia Walter, Ruifang Li-Gao, Ginger A. Metcalf, Jie Huang, Stephen S. Rich, Cornelia M. van Duijn, Nicole Soranzo, Bruce M. Psaty, Robert B. Wallace, Ursula M. Schick, Andres Metspalu, Olli T. Raitakari, Christopher J. O'Donnell, Alexander P. Reiner, Andrew D. Johnson

المساهمون: Epidemiology, Internal Medicine

المصدر: The American Journal of Human Genetics
American Journal of Human Genetics, 99(2), 481-488
American Journal of Human Genetics, 99(2), 481-488. Cell Press

مصطلحات موضوعية: 0301 basic medicine, Blood Platelets, Megakaryocyte differentiation, DNA Mutational Analysis, 030204 cardiovascular system & hematology, Biology, Blood cell, 03 medical and health sciences, 0302 clinical medicine, Proto-Oncogene Proteins, Report, medicine, Genetics, CRISPR, Humans, splice, Exome, Genetics(clinical), Progenitor cell, Genetics (clinical), Exome sequencing, Gene Editing, Platelet Count, Alternative splicing, Correction, ta3121, Hematopoietic Stem Cells, Human genetics, 3. Good health, Hematopoiesis, Repressor Proteins, Haematopoiesis, Alternative Splicing, 030104 developmental biology, medicine.anatomical_structure, Genetic Loci, CRISPR-Cas Systems, Megakaryocytes

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab4f6d80589b1a4bd405fc06eccbc542Test
http://juuli.fi/Record/0252259916Test

المؤلفون: Yingchang Lu, Lisa R. Yanek, Evangelos Evangelou, Andreas Greinacher, Leslie A. Lange, Albert Hofman, Rakale C. Quarells, Christopher J. O'Donnell, Simon de Denus, Marcus Dörr, Tamara B. Harris, Mary Cushman, Lars Wallentin, Digna R. Velez Edwards, Michelle L. O'Donoghue, Deborah A. Nickerson, Lisa Bastarache, Caterina Vacchi-Suzzi, Harvey D. White, Rasika A. Mathias, Jin Li, Santhi K. Ganesh, Leo-Pekka Lyytikäinen, Kjell Nikus, Ayush Giri, Paul Elliott, John M. Starr, Ruth J. F. Loos, Vilmundur Gudnason, Ioanna Tzoulaki, Myriam Fornage, Joshua C. Denny, Alan B. Zonderman, Caroline Hayward, Lewis C. Becker, Raha Pazoki, Guillaume Lettre, Lenore J. Launer, Ursula M. Schick, Michele K. Evans, Andrew J. Slater, Diane M. Becker, Jean-Claude Tardif, Ethan M. Lange, John D. Eicher, He Gao, James S. Floyd, Eric Boerwinkle, Paul L. Auer, Nathalie Chami, Frank J. A. van Rooij, Claudia Schurmann, Nele Friedrich, Kent D. Taylor, Andres Metspalu, Todd L. Edwards, Anne-Claire Vergnaud, Yongmei Liu, W. David Hill, Nauder Faraday, Terho Lehtimäki, Amber A. Burt, Jerome I. Rotter, Albert V. Smith, Tõnu Esko, Traci M. Bartz, Tim Kacprowski, Mike A. Nalls, Alexander P. Reiner, Ani Manichaikul, Ian J. Deary, Eric S. Torstenson, Laura M. Raffield, David C. Liewald, Ming-Huei Chen, Erwin P. Bottinger, Reedik Mägi, Andrew D. Johnson, Melissa A. Richard, Neil A. Zakai, John D. Rioux, Mika Kähönen, Stephen S. Rich, Heather M. Highland, Bruce M. Psaty, Joel N. Hirschhorn, Salman M. Tajuddin, Linda M. Polfus, Dawn M. Waterworth, James G. Wilson, Nathan Pankratz, Abbas Dehghan, Evelin Mihailov, David R. Crosslin, André G. Uitterlinden, Georg Homuth, Jennifer A. Brody

المساهمون: Gastroenterology & Hepatology, Epidemiology, Internal Medicine

المصدر: The American Journal of Human Genetics
Tajuddin, S M, Schick, U M, Eicher, J D, Chami, N, Giri, A, Brody, J A, Hill, W D, Kacprowski, T, Li, J, Lyytikäinen, L-P, Manichaikul, A, Mihailov, E, O'Donoghue, M L, Pankratz, N, Pazoki, R, Polfus, L M, Smith, A V, Schurmann, C, Vacchi-Suzzi, C, Waterworth, D M, Evangelou, E, Yanek, L R, Burt, A, Chen, M-H, van Rooij, F J A, Floyd, J S, Greinacher, A, Harris, T B, Highland, H M, Lange, L A, Liu, Y, Mägi, R, Nalls, M A, Mathias, R A, Nickerson, D A, Nikus, K, Starr, J M, Tardif, J-C, Tzoulaki, I, Velez Edwards, D R, Wallentin, L, Bartz, T M, Becker, L C, Denny, J C, Raffield, L M, Rioux, J D, Friedrich, N, Fornage, M, Gao, H, Hirschhorn, J N, Liewald, D C M, Rich, S S, Uitterlinden, A, Bastarache, L, Becker, D M, Boerwinkle, E, de Denus, S, Bottinger, E P, Hayward, C, Hofman, A, Homuth, G, Lange, E, Launer, L J, Lehtimäki, T, Lu, Y, Metspalu, A, O'Donnell, C J, Quarells, R C, Richard, M, Torstenson, E S, Taylor, K D, Vergnaud, A-C, Zonderman, A B, Crosslin, D R, Deary, I J, Dörr, M, Elliott, P, Evans, M K, Gudnason, V, Kähönen, M, Psaty, B M, Rotter, J I, Slater, A J, Dehghan, A, White, H D, Ganesh, S K, Loos, R J F, Esko, T, Faraday, N, Wilson, J G, Cushman, M, Johnson, A D, Edwards, T L, Zakai, N A, Lettre, G, Reiner, A P & Auer, P L 2016, ' Large-scale exome-wide association analysis identifies loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases ', American Journal of Human Genetics, vol. 99, no. 1, pp. 22-39 . https://doi.org/10.1016/j.ajhg.2016.05.003Test
American journal of human genetics, vol 99, iss 1
American Journal of Human Genetics, 99(1), 22-39. Cell Press

مصطلحات موضوعية: 0301 basic medicine, Quality Control, Myeloid, 1.1 Normal biological development and functioning, Genome-wide association study, Biology, Autoimmune Disease, Medical and Health Sciences, Article, 03 medical and health sciences, Underpinning research, White blood cell, medicine, Leukocytes, Genetics, Humans, 2.1 Biological and endogenous factors, Genetics(clinical), Exome, Aetiology, Genetics (clinical), Genetic association, Genetics & Heredity, Medical And Health Sciences, Neutrophil clearance, Hematopoietic stem cell differentiation, Inflammatory and immune system, Human Genome, Genetic Pleiotropy, Hematology, Biological Sciences, Acquired immune system, Stem Cell Research, 3. Good health, Blood Cell Count, 030104 developmental biology, medicine.anatomical_structure, Immune System Diseases, Genetic Loci, Immunology, Stem Cell Research - Nonembryonic - Non-Human, Genome-Wide Association Study

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::353c5b69e7bcc0868f5061124262a3d4Test
https://pure.eur.nl/en/publications/ef09e5cb-1bbc-4be2-9236-e4b21d7864c7Test

المؤلفون: Jiyang Jiang, Anbupalam Thalamuthu, Jennifer E. Ho, Anubha Mahajan, Weronica E. Ek, David A. Brown, Samuel N. Breit, Thomas J. Wang, Ulf Gyllensten, Ming-Huei Chen, Stefan Enroth, James L. Januzzi, Lars Lind, Nicola J. Armstrong, John B. Kwok, Peter R. Schofield, Wei Wen, Julian N. Trollor, Åsa Johansson, Andrew P. Morris, Ramachandran S. Vasan, Perminder S. Sachdev, Karen A. Mather

المصدر: Jiang, J, Thalamuthu, A, Ho, J E, Mahajan, A, Ek, W E, Brown, D A, Breit, S N, Wang, T J, Gyllensten, U, Chen, M-H, Enroth, S, Januzzi, J L, Lind, L, Armstrong, N J, Kwok, J B, Schofield, P R, Wen, W, Trollor, J N, Johansson, Å, Morris, A P, Vasan, R S, Sachdev, P S & Mather, K A 2018, ' A Meta-Analysis of Genome-Wide Association Studies of Growth Differentiation Factor-15 Concentration in Blood ', Frontiers in Genetics, vol. 9, pp. 97 . https://doi.org/10.3389/fgene.2018.00097Test
Frontiers in Genetics, Vol 9 (2018)
Frontiers in Genetics

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, lcsh:QH426-470, community-based individuals, Genome-wide association study, Biology, growth differentiation factor-15, 03 medical and health sciences, 0302 clinical medicine, Chromosome 19, medicine, Genetics, Macrophage, Macrophage Inhibitory Cytokine 1, macrophage inhibitory cytokine-1, Genetics (clinical), Original Research, Medicinsk genetik, genome-wide association study, chromosome 19, 3. Good health, lcsh:Genetics, 030104 developmental biology, 030220 oncology & carcinogenesis, Meta-analysis, embryonic structures, Molecular Medicine, Medical genetics, GDF15, Medical Genetics

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a03aac568d661f907b940b4ebae86234Test
https://www.research.manchester.ac.uk/portal/en/publications/a-metaanalysis-of-genomewide-association-studies-of-growth-differentiation-factor15-concentration-in-bloodTest(13d2ce8b-9ebd-4013-8e76-c6a780a0e599).html

المؤلفون: Alexander P. Reiner, Andrew D. Johnson, Ci Song, Abdou Mousas, Guillaume Lettre, Ming-Huei Chen, Jennifer E. Huffman, Paul Elliott, Ioanna Tzoulaki, Bruce M. Psaty, Georgios Ntritsos, Evangelos Evangelou, Paul L. Auer

المساهمون: Home Office, National Institute for Health Research, Imperial College Healthcare NHS Trust- BRC Funding, Medical Research Council (MRC)

المصدر: PLoS Genetics, Vol 13, Iss 8, p e1006925 (2017)
PLoS Genetics

مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, Physiology, Genome-wide association study, 030204 cardiovascular system & hematology, Biochemistry, 0302 clinical medicine, Gene Frequency, Animal Cells, Databases, Genetic, Medicine and Health Sciences, Genetics (clinical), Genetics, Principal Component Analysis, Genomics, Hematology, Body Fluids, 3. Good health, Blood, Phenotype, Female, Anatomy, Cellular Types, Research Article, Platelets, lcsh:QH426-470, Quantitative Trait Loci, Endometriosis, Mutation, Missense, Locus (genetics), Biology, Quantitative trait locus, Polymorphism, Single Nucleotide, Fibrin Fibrinogen Degradation Products, 03 medical and health sciences, Genome-Wide Association Studies, Humans, Protein Splicing, splice, Hemoglobin, Allele, Molecular Biology, Gene, Alleles, Ecology, Evolution, Behavior and Systematics, Genetic association, 0604 Genetics, Blood Cells, Genome, Human, Platelet Count, Biology and Life Sciences, Computational Biology, Proteins, Human Genetics, Plasminogen, Cell Biology, Sequence Analysis, DNA, Genome Analysis, Interleukin-33, Rhinitis, Allergic, Asthma, Blood Counts, Minor allele frequency, lcsh:Genetics, Blood-Cell Consortium, Logistic Models, 030104 developmental biology, Genetic Loci, Linear Models, Developmental Biology, Genome-Wide Association Study

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cefadab8d41af863c93f714be623d9b0Test
http://europepmc.org/articles/PMC5560754?pdf=renderTest

المؤلفون: Dennis O. Mook-Kanamori, Rehan Qayyum, Lisa R. Yanek, Luigi Ferrucci, Min-Lee Yang, David J. Stott, P. Eline Slagboom, Jin Li, Santhi K. Ganesh, Vera Grossmann, Myriam Fornage, Edith Hofer, Lewis C. Becker, Lenore J. Launer, Albert V. Smith, Brendan J. Keating, Frank J. A. van Rooij, Albert Hofman, Jun Li, Michiaki Kubo, Christian Mueller, Stella Trompet, Qiong Yang, Andrew D. Johnson, Zhao Chen, Robert J. Klein, Luanne L. Peters, Amy J. Lambert, Reinhold Schmidt, Eirini Trompouki, Kenneth Rice, Josef Coresh, Naoyuki Kamatani, Vilmundur Gudnason, Leslie A. Lange, Brian J. Abraham, Ursula M. Schick, Eric Boerwinkle, Leonard I. Zon, Bruce M. Psaty, Diane M. Becker, David Ginsburg, Gudny Eiriksdottir, Bella Hu, Mohsen Ghanbari, Dan L. Longo, Cornelia M. van Duijn, Oscar H. Franco, Beverly M. Snively, Margaux F. Keller, L. Adrienne Cupples, Yukinori Okada, James E. Hayes, Ian Ford, Jack M. Guralnik, Koichi Matsuda, J. Wouter Jukema, André G. Uitterlinden, Yoichiro Kamatani, Helena Schmidt, James G. Wilson, Michelle K. Evans, Tanja Zeller, Alan B. Zonderman, Fuu Jen Tsai, Yasaman Saba, Daniel Levy, Philipp S. Wild, Paul M. Ridker, Jaden Yang, Jer-Yuarn Wu, Janine F. Felix, Mike A. Nalls, Christopher J. O'Donnell, Karl C. Desch, Caroline S. Fox, Jennifer A. Brody, Alexander P. Reiner, Avik Choudhuri, Ayse Bilge Ozel, Abbas Dehghan, Andrew P. Morris, Ruifang Li-Gao, Daniel I. Chasman, Tamara B. Harris, Audrey Y. Chu, Toshiko Tanaka, Charles Kooperberg, Hua Tang, Song Yang, Yi Zhou, Sun Ha Jee, Kushang V. Patel, James S. Floyd, Atsushi Takahashi, Yuan-Tsong Chen, Ming-Huei Chen, Jerome I. Rotter, Li Ching Chang, Chien-Hsiun Chen

المساهمون: Epidemiology, Internal Medicine

المصدر: The American Journal of Human Genetics
AMERICAN JOURNAL OF HUMAN GENETICS
American journal of human genetics, vol 100, iss 1
American Journal of Human Genetics, 100(1), 51-63. Cell Press
American Journal of Human Genetics, 100(1), 51-63

مصطلحات موضوعية: 0301 basic medicine, Male, Linkage disequilibrium, Asia, Erythrocytes, Genome-wide association study, Locus (genetics), RBPMS, 030105 genetics & heredity, Biology, Eastern, Genome, Medical and Health Sciences, Article, Linkage Disequilibrium, 03 medical and health sciences, Genetics, Ethnicity, Animals, Humans, Erythropoiesis, Allele, Genetics (clinical), Loss function, Alleles, Zebrafish, Genetic association, Genetics & Heredity, Asia, Eastern, Human Genome, Racial Groups, RNA-Binding Proteins, BioBank Japan Project, Bayes Theorem, Hematology, Biological Sciences, R1, 3. Good health, Europe, 030104 developmental biology, Africa, Female, Genome-Wide Association Study

وصف الملف: image/jpeg; application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9899f49c26e70e49d421c0a97de1411Test
https://doi.org/10.1016/j.ajhg.2016.11.016Test