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المؤلفون: Yu Hsin Chao, Abhijit Babaji Shinde, Brett H. Graham, Hugo J. Bellen, Marco Sardiello, Vafa Bayat, Cristian Coarfa, Ann B. Moser, Myriam Baes, Nikolaos Giagtzoglou, Taraka R. Donti, Michael F. Wangler, Joseph E. Faust, Nagireddy Putluri, James A. McNew
المصدر: PLoS Genetics, Vol 13, Iss 6, p e1006825 (2017)
PLoS Geneticsمصطلحات موضوعية: 0301 basic medicine, Cancer Research, Peroxisomal Biogenesis Factor 2, Mitochondrion, Biochemistry, Peroxisomal Disorders, Mice, 0302 clinical medicine, Glucose Metabolism, Drosophila Proteins, Glycolysis, Genetics (clinical), Energy-Producing Organelles, 2. Zero hunger, Drosophila Melanogaster, Animal Models, Peroxisome, 3. Good health, Cell biology, Mitochondria, Insects, Experimental Organism Systems, Carbohydrate Metabolism, Drosophila, Metabolic Pathways, Cellular Structures and Organelles, Research Article, Arthropoda, lcsh:QH426-470, Carbohydrate metabolism, Biology, Pentose phosphate pathway, Bioenergetics, Research and Analysis Methods, Biosynthesis, 03 medical and health sciences, Model Organisms, Peroxisomal disorder, Genetics, medicine, Peroxisomes, Metabolomics, Animals, Molecular Biology, Ecology, Evolution, Behavior and Systematics, Organisms, Biology and Life Sciences, Membrane Proteins, Cell Biology, medicine.disease, Invertebrates, Metabolic pathway, lcsh:Genetics, 030104 developmental biology, Metabolism, Glucose, Mutation, Transcriptome, 030217 neurology & neurosurgery
وصف الملف: Electronic-eCollection; application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b5b663b1387bb1b5929834173f02cecTest
http://europepmc.org/articles/PMC5480855?pdf=renderTest -
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المؤلفون: Marco Sardiello, Joel R. Neilson, Fred A. Pereira, Michelle L. Seymour, Rituraj Pal, Hemanth R. Nelvagal, Usama Saleem, Jonathan D. Cooper, Parisa Lotfi, Dennis Y. Tse, Gary R. Stinnett, Michela Palmieri, Samuel M. Wu, Robia G. Pautler, Laura Bremner, Vitaliy V. Bondar, Deepthi Sanagasetti, Arindam Chaudhury, George G. Rodney, Lakshya Bajaj
المصدر: Palmieri, M, Pal, R, Nelvagal, H R, Lotfi, P, Stinnett, G R, Seymour, M L, Chaudhury, A, Bajaj, L, Bondar, V V, Bremner, L, Saleem, U, Tse, D Y, Sanagasetti, D, Wu, S M, Neilson, J R, Pereira, F A, Pautler, R G, Rodney, G G, Cooper, J D & Sardiello, M 2017, ' MTORC1-independent TFEB activation via Akt inhibition promotes cellular clearance in neurodegenerative storage diseases ', Nature Communications, vol. 8, 14338 . https://doi.org/10.1038/ncomms14338Test
Nature Communications, Vol 8, Iss 1, Pp 1-19 (2017)
Nature Communications
Nature communications, vol 8, iss 1مصطلحات موضوعية: Male, 0301 basic medicine, General Physics and Astronomy, Basic helix-loop-helix leucine zipper transcription factors, mTORC1, Neurodegenerative, Transgenic, Mice, Heterocyclic Compounds, 2.1 Biological and endogenous factors, Aetiology, Phosphorylation, Neurons, Membrane Glycoproteins, Multidisciplinary, Basic Helix-Loop-Helix Leucine Zipper Transcription Factors, Chemistry, Brain, Neurodegenerative Diseases, Corrigenda, 3. Good health, Cell biology, Neuroprotective Agents, Gene Knockdown Techniques, Signal transduction, Heterocyclic Compounds, 3-Ring, Signal Transduction, Batten disease, Science, Primary Cell Culture, Mice, Transgenic, Mechanistic Target of Rapamycin Complex 1, 3-Ring, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Rare Diseases, Autophagy, medicine, Animals, Humans, Protein kinase B, Cell Nucleus, Animal, Neurosciences, Trehalose, General Chemistry, Fibroblasts, medicine.disease, Disease Models, Animal, Orphan Drug, 030104 developmental biology, Hela Cells, Astrocytes, Disease Models, Immunology, TFEB, Proto-Oncogene Proteins c-akt, HeLa Cells, Molecular Chaperones
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85d8d00ef458abc1426f29af32c0a4a9Test
https://kclpure.kcl.ac.uk/ws/files/66723848/mTORC1_independent_TFEB_PALMIERI_Publishedonline6February2017_GOLD_VoR_CC_BY_.pdfTest -
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المؤلفون: Li Yang, Alberto di Ronza, Baiping Wang, Marco Sardiello, Michela Palmieri, Hongmei Li, Virginia M.-Y. Lee, Yin Xu, Heidi Martini-Stoica, Dan B. Swartzlander, Vinicia Assunta Polito, Hui Zheng, Andrea Ballabio
المساهمون: Polito, Va, Li, H, Martini Stoica, H, Wang, B, Yang, L, Xu, Y, Swartzlander, Db, Palmieri, M, di Ronza, A, Lee, Vm, Sardiello, M, Ballabio, Andrea, Zheng, H.
المصدر: EMBO Molecular Medicine
مصطلحات موضوعية: PTEN, ALZHEIMERS-DISEASE, Basic helix-loop-helix leucine zipper transcription factors, Mice, Transgenic, tau Proteins, Biology, 03 medical and health sciences, 0302 clinical medicine, Alzheimer Disease, autophagy-lysosomal pathway, medicine, Autophagy, Tensin, Animals, Research Articles, 030304 developmental biology, Genetics, 0303 health sciences, TFEB, Basic Helix-Loop-Helix Leucine Zipper Transcription Factors, Neurodegeneration, tauopathy, PTEN Phosphohydrolase, Neurofibrillary tangle, Neurofibrillary Tangles, Alzheimer's disease, medicine.disease, 3. Good health, Cell biology, Mice, Inbred C57BL, Gene Expression Regulation, Tauopathies, Nerve Degeneration, biology.protein, Molecular Medicine, Tauopathy, Lysosomes, 030217 neurology & neurosurgery
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64df5a2da517c11fa23a22bb5c3204bcTest
https://pubmed.ncbi.nlm.nih.gov/25069841Test -
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المؤلفون: Yongping Zhang, Kartik Venkatachalam, Hector Sandoval, Roy V. Sillitoe, Weina Shang, Sonal Nagarkar Jaiswal, Chao Tong, Marco Sardiello, Hugo J. Bellen, Upasana Gala, Lita Duraine, Xuejun Tian, Manish Jaiswal, Heng-Yu Fan, Shinya Yamamoto, Alberto di Ronza
المصدر: PLoS Biology
PLoS Biology, Vol 13, Iss 3, p e1002103 (2015)مصطلحات موضوعية: Male, QH301-705.5, Endosome, Primary Cell Culture, Cellular homeostasis, Endosomes, Vacuole, Biology, Membrane Fusion, Synaptic Transmission, Synaptic vesicle, General Biochemistry, Genetics and Molecular Biology, Mice, Calcium Channels, N-Type, Cerebellum, Phagosomes, Autophagy, Animals, Drosophila Proteins, Homeostasis, Biology (General), Phagosome, Mice, Knockout, Neurons, Cell fusion, General Immunology and Microbiology, General Neuroscience, Calcium channel, Lipid bilayer fusion, 3. Good health, Cell biology, Mice, Inbred C57BL, Drosophila melanogaster, Gene Expression Regulation, Calcium, Female, Calcium Channels, Synaptic Vesicles, Lysosomes, General Agricultural and Biological Sciences, Research Article
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8190e181eb14d33439c00c7fb7bce5c0Test
https://doi.org/10.1371/journal.pbio.1002103Test -
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المؤلفون: James A. Loehr, Poulami Basu Thakur, Reem Abo-Zahrah, Marco Sardiello, Michela Palmieri, Tanner O. Monroe, Shumin Li, Rituraj Pal, George G. Rodney
المصدر: Nature communications
مصطلحات موضوعية: Male, mdx mouse, Duchenne muscular dystrophy, General Physics and Astronomy, medicine.disease_cause, General Biochemistry, Genetics and Molecular Biology, Article, Mice, Lysosome, medicine, Autophagy, Animals, Immunoprecipitation, Muscular dystrophy, PI3K/AKT/mTOR pathway, Genetics, Mice, Knockout, Multidisciplinary, Chemistry, General Chemistry, Muscular Dystrophy, Animal, medicine.disease, 3. Good health, Cell biology, Muscular Dystrophy, Duchenne, Disease Models, Animal, Oxidative Stress, medicine.anatomical_structure, Reactive Oxygen Species, Oxidative stress, Proto-oncogene tyrosine-protein kinase Src
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c464698e105ec658ccfc5dc773a97d49Test
http://europepmc.org/articles/PMC4101811Test