المؤلفون: Luis M. Botana, Ana I. Neto, Verónica Rey, Ana M. Botana, Aldo Barreiro, Meryem Hassouani, Vitor Vasconcelos, Marisa Silva, Brahim Sabour, Manfred Kaufmann

المساهمون: Centro Interdisciplinar de Investigação Marinha e Ambiental, Universidade de Santiago de Compostela. Departamento de Farmacoloxía, Farmacia e Tecnoloxía Farmacéutica, Universidade de Santiago de Compostela. Departamento de Química Analítica, Nutrición e Bromatoloxía, CIIMAR - Centro Interdisciplinar de Investigação Marinha e Ambiental

المصدر: Toxins
Volume 10
Issue 9
Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
instname
Toxins, Vol 10, Iss 9, p 362 (2018)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

مصطلحات موضوعية: Ophidiaster ophidianus, 0106 biological sciences, Patella aspera, Charonia lampas, Health, Toxicology and Mutagenesis, saxitoxin, lcsh:Medicine, Arbacia lixula, Toxicology, n sulfocarbamoyl gonyautoxin 3, 01 natural sciences, n sulfocarbamoyl gonyautoxin 2, Echinaster sepositus, Faculdade de Ciências da Vida, chemistry.chemical_compound, Water Pollutants, Atlantic Ocean, post-column oxidation liquid chromatography, biology, decarbamoyl saxitoxin, Fishes, Umbraculum umbraculum, Madeira island, Patella ordinaria, new vectors, neosaxitoxin, Pollicipes pollicipes, unclassified drug, 3. Good health, Shellfish poisoning, São Miguel island, Morocco, Benthic zone, Diadema africanum, Environmental Monitoring, Madeira island (Portugal), high performance liquid chromatography, Limit value, invertebrate, paralytic shellfish toxins, Article, medicine, Animals, Shellfish Poisoning, Azores archipelago, 14. Life underwater, Stramonita haemastoma, liquid chromatography-mass spectrometry, Invertebrate, Saxitoxin, nonhuman, 010604 marine biology & hydrobiology, 010401 analytical chemistry, lcsh:R, biology.organism_classification, medicine.disease, Invertebrates, Crustacean, shellfish toxin, 0104 chemical sciences, São Miguel island, Açores (Portugal), gonyautoxin, Fishery, chemistry, Paracentrotus lividus, decarbamoyl gonyautoxin 2, gonyautoxin 1, gonyautoxin 2, gonyautoxin 3, decarbamoyl gonyautoxin 3, gonyautoxin 4, gonyautoxin 5

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38ec95954752f5e9696cb3fda46e68abTest

المؤلفون: Paula Abal, Mercedes R. Vieytes, M. Carmen Louzao, Cristina Carrera, Luis M. Botana, Natalia Vilariño, Eva Cagide

المساهمون: Centro Interdisciplinar de Investigação Marinha e Ambiental

المصدر: Toxins
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Toxins, Vol 10, Iss 8, p 324 (2018)

مصطلحات موضوعية: 0301 basic medicine, Ciguatoxin, Health, Toxicology and Mutagenesis, lcsh:Medicine, Poison control, Review, acute toxicity, Toxicology, medicine.disease_cause, biotoxin, 03 medical and health sciences, intoxication, Environmental health, Okadaic Acid, Medicine, Animals, Humans, Shellfish Poisoning, Spiro Compounds, Chronic toxicity, Acrylamides, toxicity equivalency factor, business.industry, Toxin, lcsh:R, Acute intoxication, Consumer protection, Acute toxicity, 3. Good health, 030104 developmental biology, 13. Climate action, Marine Toxins, business, Marine toxin, chronic toxicity

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1611856f3db909ce7ee6b7760d3264eTest

المؤلفون: Shuji Yamashita, Mercedes R. Vieytes, María Roel, Víctor Martín, Juan A. Rubiolo, Carmen Vale, Luis M. Botana, Masahiro Hirama

المصدر: Chemical Research in Toxicology. 28:1109-1119

مصطلحات موضوعية: Voltage-Gated Sodium Channels, Biology, Toxicology, Ciguatoxins, Mice, Structure-Activity Relationship, 03 medical and health sciences, 0302 clinical medicine, Homeostatic plasticity, Animals, 030304 developmental biology, Cerebral Cortex, Neurons, Membrane potential, 0303 health sciences, Synaptic scaling, Arc (protein), Dose-Response Relationship, Drug, Sodium channel, Glutamate receptor, General Medicine, 3. Good health, Electrophysiology, Biochemistry, Synapses, Excitatory postsynaptic potential, Neuroscience, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08f8bec7b0127807263a6e6d3da453d1Test
https://doi.org/10.1021/tx500506qTest

المؤلفون: Luis M. Botana, Amparo Alfonso, Mercedes R. Vieytes, Andrea Fernández-Araujo

المصدر: Toxicology. 329:60-72

مصطلحات موضوعية: Programmed cell death, Cell Survival, Cellular differentiation, Mollusk Venoms, Apoptosis, Transferrin receptor, Biology, Toxicology, YTX, 03 medical and health sciences, 0302 clinical medicine, Antigens, CD, Receptors, Transferrin, LC3, Autophagy, Humans, Gene Silencing, Mechanistic target of rapamycin, PI3K/AKT/mTOR pathway, 030304 developmental biology, Sirolimus, 0303 health sciences, TOR Serine-Threonine Kinases, Oxocins, Cell Differentiation, CREB-Binding Protein, Cyclic Nucleotide Phosphodiesterases, Type 4, 3. Good health, Cell biology, TfR, 030220 oncology & carcinogenesis, mTOR, biology.protein, K562 Cells, Microtubule-Associated Proteins, Intracellular, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42ca5541593924288554f4dfbecab738Test

المؤلفون: H. López-Alonso, F. V. Vega, Mercedes R. Vieytes, Luis M. Botana, Eva Ternon, Olivier P. Thomas, María Roel, Juan A. Rubiolo

المصدر: British Journal of Pharmacology. 171:1655-1667

مصطلحات موضوعية: Pharmacology, medicine.diagnostic_test, Cell, Cell migration, Biology, 3. Good health, Flow cytometry, Cell biology, Focal adhesion, medicine.anatomical_structure, Cell culture, medicine, Cytotoxic T cell, Cytotoxicity, Cell adhesion

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::4bf3c7495188daf135fea99940f0f2bbTest
https://doi.org/10.1111/bph.12552Test

المؤلفون: Mercedes R. Vieytes, Luis M. Botana, D. Fernández, M. C. Louzao, María Fraga, Natalia Vilariño

المساهمون: Universidade de Santiago de Compostela. Departamento de Farmacoloxía, Universidade de Santiago de Compostela. Departamento de Fisioloxía

المصدر: Toxins
Toxins, Vol 6, Iss 1, Pp 211-228 (2014)
Toxins; Volume 6; Issue 1; Pages: 211-228
Minerva: Repositorio Institucional de la Universidad de Santiago de Compostela
Universidad de Santiago de Compostela (USC)
Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
instname

مصطلحات موضوعية: Okadaic acid, Health, Toxicology and Mutagenesis, lcsh:Medicine, Pharmacology, Toxicology, medicine.disease_cause, Median lethal dose, Intestinal absorption, Annexin V, occludin, chemistry.chemical_compound, dinophysistoxin-2, dinophysistoxin-1, Immunoassay, 0303 health sciences, Microscopy, Confocal, 030302 biochemistry & molecular biology, okadaic acid, Caco-2, intestinal permeability, trans-epithelial electric resistance, annexin V, Luminex, immunoassay, 3. Good health, Dinophysistoxin-1, Biochemistry, Dinophysistoxin-2, Absorption (skin), Biology, Intestinal permeability, Article, Lethal Dose 50, 03 medical and health sciences, Occludin, Trans-epithelial electric resistance, medicine, Humans, 14. Life underwater, Pyrans, 030304 developmental biology, Toxin, Lethal dose, lcsh:R, medicine.disease, Intestinal Absorption, chemistry, Marine Toxins, Caco-2 Cells, Marine toxin

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a829b35c2b640b6ed4ea43b5636cb2d7Test

المؤلفون: Gaël Lecellier, Luis M. Botana, Mael Nicolas, Marc Gaysinski, E. Alonso-Lopes, Sara F. Ferreiro, Soizic Prado, Olivier P. Thomas, Nicolas J. Martin, Phila Raharivelomanana, Florent Barbault, Christian Paetz

المساهمون: Ecosystèmes Insulaires Océaniens (UMR 241) (EIO), Institut de Recherche pour le Développement (IRD)-Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER)-Université de la Polynésie Française (UPF)-Institut Louis Malardé [Papeete] (ILM), Institut de Recherche pour le Développement (IRD), Department of Pharmacology, Universidade de Santiago de Compostela, Muséum national d'Histoire naturelle (MNHN), Interfaces, Traitements, Organisation et Dynamique des Systèmes (ITODYS (UMR_7086)), Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Géoazur (GEOAZUR 7329), Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de la Côte d'Azur, Université Côte d'Azur (UCA)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud]), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), Max Planck Institute for Chemical Ecology, Max-Planck-Gesellschaft, Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7), Institut national des sciences de l'Univers (INSU - CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])-Centre National de la Recherche Scientifique (CNRS)-Observatoire de la Côte d'Azur, Université Côte d'Azur (UCA)-Université Côte d'Azur (UCA), Université de la Polynésie Française (UPF)-Institut Louis Malardé [Papeete] (ILM), Institut de Recherche pour le Développement (IRD)-Institut de Recherche pour le Développement (IRD)-Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER), Université Paris Diderot - Paris 7 (UPD7)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Université Côte d'Azur (UCA)-Institut national des sciences de l'Univers (INSU - CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])-Centre National de la Recherche Scientifique (CNRS)-Observatoire de la Côte d'Azur, Université Côte d'Azur (UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)

المصدر: Planta Medica
Planta Medica, Georg Thieme Verlag, 2016, 81 (S 01), pp.S1-S381. ⟨10.1055/s-0036-1596521⟩

مصطلحات موضوعية: Pharmacology, Rauvolfia, Phylogenetic tree, Indole alkaloid, Organic Chemistry, Pharmaceutical Science, [SDU.STU]Sciences of the Universe [physics]/Earth Sciences, 15. Life on land, Biology, biology.organism_classification, DNA barcoding, 3. Good health, Analytical Chemistry, Complementary and alternative medicine, Genus, visual_art, Drug Discovery, Botany, visual_art.visual_art_medium, Rauvolfia nukuhivensis, Molecular Medicine, Bioassay, Bark

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c4fb46bc61699fc4c0c24ee4f756039Test
https://hal.archives-ouvertes.fr/hal-02148636Test

المؤلفون: María Roel, Luis M. Botana, Laura Sánchez, Rafael López, Juan A. Rubiolo, Pablo Cabezas-Sainz, Olivier P. Thomas, Siguara B. L. Silva, Jorge Guerra-Varela

المساهمون: Department of Pharmacology, Universidade de Santiago de Compostela, Department Farmacologia, University of Santiago de Compostela, Departamento de Genética, Universidad de Santiago de Compostela [Spain] (USC), Laboratoire de Pharmacognosie (BioCIS), Université Paris-Sud - Paris 11 (UP11)-Centre National de la Recherche Scientifique (CNRS), School of Chemistry, Marine Biodiscovery, National University of Ireland Galway, Géoazur (GEOAZUR 7329), Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de la Côte d'Azur, Université Côte d'Azur (UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud]), Translational Medical Oncology, Health Research Institute of Santiago, Universidade de Santiago de Compostela. Departamento de Farmacoloxía, Farmacia e Tecnoloxía Farmacéutica, Universidade de Santiago de Compostela. Departamento de Zooloxía, Xenética e Antropoloxía Física, Institut national des sciences de l'Univers (INSU - CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])-Centre National de la Recherche Scientifique (CNRS)-Observatoire de la Côte d'Azur, Université Côte d'Azur (UCA)-Université Côte d'Azur (UCA), Université Côte d'Azur (UCA)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])

المصدر: Oncotarget
Oncotarget, Impact journals, 2016, 7 (50), ⟨10.18632/oncotarget.13068⟩
Minerva: Repositorio Institucional de la Universidad de Santiago de Compostela
Universidad de Santiago de Compostela (USC)
Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
instname

مصطلحات موضوعية: 0301 basic medicine, Time Factors, Colorectal cancer, Cell, Apoptosis, Cell Cycle Proteins, p53-mediated g(1) arrest, 0302 clinical medicine, anoikis, Zebrafish, Cytoskeleton, Cyclin, Membrane Potential, Mitochondrial, zebrafish xenograft model, biology, Kinase, Caspase 3, Hep G2 Cells, 3. Good health, Cancer treatment, Tumor Burden, mitochondria, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, MCF-7 Cells, Colorectal Neoplasms, HT29 Cells, Research Paper, Signal Transduction, Cell Cycle Inhibition, Cell Survival, [SDU.STU]Sciences of the Universe [physics]/Earth Sciences, Antineoplastic Agents, cancer treatment, 03 medical and health sciences, Inhibitory Concentration 50, crambescidins, Alkaloids, medicine, Cell Adhesion, Animals, Humans, Spiro Compounds, sponge crambe-crambe, cell cycle inhibition, Guanidine, Cell Proliferation, Dose-Response Relationship, Drug, pathway, human cancer, medicine.disease, biology.organism_classification, G1 Phase Cell Cycle Checkpoints, Xenograft Model Antitumor Assays, 030104 developmental biology, Cancer research, cells, cyclin-dependent kinases, progression

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f798c27822dad8d64cc74b39d7a9f31aTest
https://hal.archives-ouvertes.fr/hal-01741180Test

المؤلفون: Klaus D. Feussner, Miriam A. Dam, Jioji N. Tabudravu, Luis M. Botana, Marcel Jaspars, Mostafa E. Rateb, Rebeca Alvariño, Marta Leirós, Eva Alonso

المساهمون: Universidade de Santiago de Compostela. Departamento de Farmacoloxía, Farmacia e Tecnoloxía Farmacéutica

المصدر: Marine Drugs; Volume 14; Issue 11; Pages: 197
Marine Drugs
Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
instname
Marine Drugs, Vol 14, Iss 11, p 197 (2016)

مصطلحات موضوعية: 0301 basic medicine, Antioxidant, F163, medicine.medical_treatment, neurons, Pharmaceutical Science, Quinolones, Mitochondrion, medicine.disease_cause, Antioxidants, Mice, chemistry.chemical_compound, Pregnancy, Drug Discovery, oxidative stress, nrf2, lcsh:QH301-705.5, Pharmacology, Toxicology and Pharmaceutics (miscellaneous), Neurons, Marine sponge, chemistry.chemical_classification, biology, Glutathione, Mitochondria, Porifera, 3. Good health, Neuroprotective Agents, Biochemistry, Catalase, Female, Zyzzya, marine sponge, NF-E2-Related Factor 2, Primary Cell Culture, Article, Cell Line, Structure-Activity Relationship, 03 medical and health sciences, Investigación::32 Ciencias médicas::3209 Farmacología [Materias], makaluvamine, Cell Line, Tumor, medicine, Animals, Structure–activity relationship, Pyrroles, Pyrroloiminoquinones, Reactive oxygen species, Activator (genetics), Hydrogen Peroxide, 030104 developmental biology, lcsh:Biology (General), chemistry, Oxidative stress, biology.protein, Reactive Oxygen Species, Makaluvamine

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a360b05621321b62be6a8551c8c8b6a9Test

المؤلفون: Jon Andoni Sánchez, Amparo Alfonso, Ines Rodriguez, Eva Alonso, Manuel Cifuentes, Roberto Bermúdez, Mostafa E Rateb, Marcel Jaspars, Wael E Houssen, Rainer Ebel, Jioji Tabudravu, Luis M Botana

المصدر: Frontiers in Immunology
Frontiers in Immunology, Vol 7 (2016)

مصطلحات موضوعية: lcsh:Immunologic diseases. Allergy, 0301 basic medicine, Receptor expression, Immunology, Inflammation, 03 medical and health sciences, Immune system, Spongionella sp, Extracellular, medicine, Immunology and Allergy, chemotaxis, Receptor, Original Research, biology, Chemotaxis, C720, 3. Good health, Cell biology, 030104 developmental biology, Biochemistry, inflammation, Concanavalin A, CD147, biology.protein, medicine.symptom, Signal transduction, lcsh:RC581-607, cyclophilin A

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e56c9065a340b28b1e724cd9757c47eTest
https://doi.org/10.3389/fimmu.2016.00452Test