المؤلفون: Rebeca Alvariño, Eva Alonso, Amparo Alfonso, Luis M. Botana, Rodney Lacret, Olga Genilloud, Fernando Reyes, Daniel Oves-Costales

المصدر: Molecular Pharmaceutics. 16:1456-1466

مصطلحات موضوعية: Amyloid beta, p38 mitogen-activated protein kinases, Pharmaceutical Science, tau Proteins, 02 engineering and technology, In Vitro Techniques, Pharmacology, medicine.disease_cause, 030226 pharmacology & pharmacy, Neuroprotection, Neuroblastoma, 03 medical and health sciences, 0302 clinical medicine, Drug Discovery, medicine, Animals, Viability assay, Neuroinflammation, Inflammation, Amyloid beta-Peptides, biology, Microglia, Chemistry, Kinase, 021001 nanoscience & nanotechnology, Streptomyces, 3. Good health, Oxidative Stress, Neuroprotective Agents, medicine.anatomical_structure, biology.protein, Molecular Medicine, Macrolides, Reactive Oxygen Species, 0210 nano-technology, Oxidative stress

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae7734c56ea1419fcf012795092ee004Test
https://doi.org/10.1021/acs.molpharmaceut.8b01090Test

المؤلفون: Toshiyuki Suzuki, Luis M. Botana, Mercedes R. Vieytes, Ryuichi Watanabe, M. Carmen Louzao, Paula Abal, Celia Costas, Natalia Vilariño, Ana M. Botana

المساهمون: Universidade de Santiago de Compostela. Departamento de Farmacoloxía, Farmacia e Tecnoloxía Farmacéutica, Universidade de Santiago de Compostela. Departamento de Fisioloxía, Universidade de Santiago de Compostela. Departamento de Química Analítica, Nutrición e Bromatoloxía

المصدر: Marine Drugs
Volume 19
Issue 1
Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
instname
Minerva: Repositorio Institucional de la Universidad de Santiago de Compostela
Universidad de Santiago de Compostela (USC)
Marine Drugs, Vol 19, Iss 23, p 23 (2021)

مصطلحات موضوعية: Okadaic acid, LC/MS/MS, Pharmaceutical Science, Pharmacology, medicine.disease_cause, Mass Spectrometry, Article, 03 medical and health sciences, chemistry.chemical_compound, Mice, okadaic acid, Drug Discovery, medicine, Toxicokinetics, Animals, Shellfish Poisoning, Large intestine, Tissue Distribution, dinophysistoxin-2, Pharmacology, Toxicology and Pharmaceutics (miscellaneous), lcsh:QH301-705.5, dinophysistoxin-1, Chromatography, High Pressure Liquid, 030304 developmental biology, Shellfish, 0303 health sciences, Gastrointestinal tract, Dose-Response Relationship, Drug, Toxin, Stomach, 030302 biochemistry & molecular biology, Toxicokinetic, Small intestine, toxicokinetic, 3. Good health, Intestines, Mice, Inbred C57BL, Dinophysistoxin-1, medicine.anatomical_structure, chemistry, lcsh:Biology (General), Toxicity, Dinophysistoxin-2, Female, Marine Toxins

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2bb0037bf3cdd1133c9cc8208420911Test

المؤلفون: Gaël Lecellier, Luis M. Botana, Mael Nicolas, Marc Gaysinski, E. Alonso-Lopes, Sara F. Ferreiro, Soizic Prado, Olivier P. Thomas, Nicolas J. Martin, Phila Raharivelomanana, Florent Barbault, Christian Paetz

المساهمون: Ecosystèmes Insulaires Océaniens (UMR 241) (EIO), Institut de Recherche pour le Développement (IRD)-Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER)-Université de la Polynésie Française (UPF)-Institut Louis Malardé [Papeete] (ILM), Institut de Recherche pour le Développement (IRD), Department of Pharmacology, Universidade de Santiago de Compostela, Muséum national d'Histoire naturelle (MNHN), Interfaces, Traitements, Organisation et Dynamique des Systèmes (ITODYS (UMR_7086)), Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Géoazur (GEOAZUR 7329), Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de la Côte d'Azur, Université Côte d'Azur (UCA)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud]), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), Max Planck Institute for Chemical Ecology, Max-Planck-Gesellschaft, Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7), Institut national des sciences de l'Univers (INSU - CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])-Centre National de la Recherche Scientifique (CNRS)-Observatoire de la Côte d'Azur, Université Côte d'Azur (UCA)-Université Côte d'Azur (UCA), Université de la Polynésie Française (UPF)-Institut Louis Malardé [Papeete] (ILM), Institut de Recherche pour le Développement (IRD)-Institut de Recherche pour le Développement (IRD)-Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER), Université Paris Diderot - Paris 7 (UPD7)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Université Côte d'Azur (UCA)-Institut national des sciences de l'Univers (INSU - CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])-Centre National de la Recherche Scientifique (CNRS)-Observatoire de la Côte d'Azur, Université Côte d'Azur (UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)

المصدر: Planta Medica
Planta Medica, Georg Thieme Verlag, 2016, 81 (S 01), pp.S1-S381. ⟨10.1055/s-0036-1596521⟩

مصطلحات موضوعية: Pharmacology, Rauvolfia, Phylogenetic tree, Indole alkaloid, Organic Chemistry, Pharmaceutical Science, [SDU.STU]Sciences of the Universe [physics]/Earth Sciences, 15. Life on land, Biology, biology.organism_classification, DNA barcoding, 3. Good health, Analytical Chemistry, Complementary and alternative medicine, Genus, visual_art, Drug Discovery, Botany, visual_art.visual_art_medium, Rauvolfia nukuhivensis, Molecular Medicine, Bioassay, Bark

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c4fb46bc61699fc4c0c24ee4f756039Test
https://hal.archives-ouvertes.fr/hal-02148636Test

المؤلفون: Klaus D. Feussner, Miriam A. Dam, Jioji N. Tabudravu, Luis M. Botana, Marcel Jaspars, Mostafa E. Rateb, Rebeca Alvariño, Marta Leirós, Eva Alonso

المساهمون: Universidade de Santiago de Compostela. Departamento de Farmacoloxía, Farmacia e Tecnoloxía Farmacéutica

المصدر: Marine Drugs; Volume 14; Issue 11; Pages: 197
Marine Drugs
Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
instname
Marine Drugs, Vol 14, Iss 11, p 197 (2016)

مصطلحات موضوعية: 0301 basic medicine, Antioxidant, F163, medicine.medical_treatment, neurons, Pharmaceutical Science, Quinolones, Mitochondrion, medicine.disease_cause, Antioxidants, Mice, chemistry.chemical_compound, Pregnancy, Drug Discovery, oxidative stress, nrf2, lcsh:QH301-705.5, Pharmacology, Toxicology and Pharmaceutics (miscellaneous), Neurons, Marine sponge, chemistry.chemical_classification, biology, Glutathione, Mitochondria, Porifera, 3. Good health, Neuroprotective Agents, Biochemistry, Catalase, Female, Zyzzya, marine sponge, NF-E2-Related Factor 2, Primary Cell Culture, Article, Cell Line, Structure-Activity Relationship, 03 medical and health sciences, Investigación::32 Ciencias médicas::3209 Farmacología [Materias], makaluvamine, Cell Line, Tumor, medicine, Animals, Structure–activity relationship, Pyrroles, Pyrroloiminoquinones, Reactive oxygen species, Activator (genetics), Hydrogen Peroxide, 030104 developmental biology, lcsh:Biology (General), chemistry, Oxidative stress, biology.protein, Reactive Oxygen Species, Makaluvamine

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a360b05621321b62be6a8551c8c8b6a9Test

المؤلفون: Olivier P. Thomas, Mercedes R. Vieytes, Juan A. Rubiolo, F. V. Vega, H. López-Alonso, Eva Ternon, Luis M. Botana

المساهمون: Universidade de Santiago de Compostela. Departamento de Farmacoloxía, Universidade de Santiago de Compostela. Departamento de Fisioloxía

المصدر: Marine Drugs; Volume 11; Issue 11; Pages: 4419-4434
Marine Drugs
Minerva: Repositorio Institucional de la Universidad de Santiago de Compostela
Universidad de Santiago de Compostela (USC)
Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
instname
Marine Drugs, Vol 11, Iss 11, Pp 4419-4434 (2013)

مصطلحات موضوعية: G2 Phase, Programmed cell death, Cell cycle checkpoint, Cell division, Saccharomyces cerevisiae, Pharmaceutical Science, Apoptosis, crambescidine-816, Antifungal, Article, Cell cycle arrest, 03 medical and health sciences, chemistry.chemical_compound, Alkaloids, 0302 clinical medicine, Drug Discovery, Spiro Compounds, lcsh:QH301-705.5, Pharmacology, Toxicology and Pharmaceutics (miscellaneous), Guanidine, Cell Size, 030304 developmental biology, Membrane Potential, Mitochondrial, 0303 health sciences, Crambescidine-816, Cell Death, biology, apoptosis, Cell Cycle Checkpoints, Cell cycle, biology.organism_classification, Yeast, Fungicides, Industrial, 3. Good health, Cell biology, lcsh:Biology (General), Biochemistry, chemistry, cell cycle arrest, 030220 oncology & carcinogenesis, antifungal, Cell Division, DNA

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cf4f7648931adf32694ebcf0c3d93d3Test
https://doi.org/10.3390/md11114419Test

المؤلفون: Luis M. Botana, Olivier P. Thomas, Juan A. Rubiolo, María Roel, Mercedes R. Vieytes, Eva Ternon

المساهمون: Universidade de Santiago de Compostela. Departamento de Farmacoloxía, Universidade de Santiago de Compostela. Departamento de Fisioloxía, Universidade de Santiago de Compostela [Spain] (USC ), Institut de Chimie de Nice (ICN), Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Côte d'Azur (UCA)-Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA), Institut méditerranéen de biodiversité et d'écologie marine et continentale (IMBE), Avignon Université (AU)-Aix Marseille Université (AMU)-Institut de recherche pour le développement [IRD] : UMR237-Centre National de la Recherche Scientifique (CNRS), Department Farmacologia, University of Santiago de Compostela, FEDER cofunded-grants. CDTI and Technological Funds, supported by Ministerio de Economía y Competitividad, AGL2012-40185-CO2-01 and Consellería de Cultura, Educación e Ordenación Universitaria, GRC2013-016, and by Axencia Galega de Innovación, Spain, ITC-20133020 SINTOX, IN852A 2013/16-3 MYTIGAL. CDTIunderISIP Programme, Spain, IDI-20130304 APTAFOOD. European Union’s 7th Framework Programme managed by Research Executive Agency (FP7/2007-2013) under grant agreement Nos. 265409 µAQUA, 315285 CIGUATOOLS and 312184 PHARMASEA., Université Nice Sophia Antipolis (1965 - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Côte d'Azur (UCA)

المصدر: Minerva: Repositorio Institucional de la Universidad de Santiago de Compostela
Universidad de Santiago de Compostela (USC)
Marine Drugs, Vol 13, Iss 8, Pp 4633-4653 (2015)
Marine drugs
Marine drugs, MDPI, 2015, 13 (8), pp.4633--4653. ⟨10.3390/md13084633⟩
Marine drugs, 2015, 13 (8), pp.4633--4653. ⟨10.3390/md13084633⟩
Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
instname
Marine Drugs
Volume 13
Issue 8
Pages 4633-4653

مصطلحات موضوعية: Pharmaceutical Science, antioxidant effect, Crambescin-C1, Transcriptome, Biological Factors, Crambe Sponge, chemistry.chemical_compound, Crambe crambe, Sponge-derived compounds, Drug Discovery, Metallothionein, Guanidine, Pharmacology, Toxicology and Pharmaceutics (miscellaneous), lcsh:QH301-705.5, Hep G2 Cells, Antioxidant effect, Cytoprotection, 3. Good health, Cell biology, Hepg2 cells, Biology, Resting Phase, Cell Cycle, crambescin-C1, Article, Alkaloids, Cell Line, Tumor, Botany, Animals, Humans, cell cycle inhibition, Cell cycle inhibition, Cell Proliferation, Transcriptome profiling, Cell growth, G1 Phase, transcriptome profiling, metallothionein, Crambescin-A1, Pyrimidines, chemistry, crambescin-A1, lcsh:Biology (General), [SDE.BE]Environmental Sciences/Biodiversity and Ecology, sponge-derived compounds

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c27f12c14abe1b1e1e7928ed60a72fecTest
http://hdl.handle.net/10347/23611Test

المؤلفون: Mercedes R. Vieytes, Amparo Alfonso, Luis M. Botana

المساهمون: Universidade de Santiago de Compostela. Departamento de Farmacoloxía, Farmacia e Tecnoloxía Farmacéutica, Universidade de Santiago de Compostela. Departamento de Fisioloxía

المصدر: Marine Drugs, Vol 14, Iss 2, p 30 (2016)
Marine Drugs
Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
instname

مصطلحات موضوعية: 0301 basic medicine, Pharmaceutical Science, Apoptosis, Review, Signal transduction, Pharmacology, Bioinformatics, medicine.disease_cause, Second Messenger Systems, cellular death, chemistry.chemical_compound, Drug Discovery, lcsh:QH301-705.5, Pharmacology, Toxicology and Pharmaceutics (miscellaneous), Cytoskeleton, Glucose metabolism, Cell Death, Oxocins, apoptosis, cytoskeleton, 3. Good health, Second messenger system, Dinoflagellida, Cellular death, Yessotoxin, signal transduction, Intracellular, autophagy, glucose metabolism, Mollusk Venoms, Biology, 03 medical and health sciences, Immune system, Yessotoxin (YTX), Autophagy, medicine, Animals, Humans, Shellfish, 030102 biochemistry & molecular biology, Toxin, immune system, 030104 developmental biology, lcsh:Biology (General), chemistry, yessotoxin (YTX), Alzheimer

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c96a307142be819c2fcd04075460c5aTest
https://doi.org/10.3390/md14020030Test