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المؤلفون: Lukas Tamayo-Orrego, Samer Salameh, Grant W. Brown, Andrew P. Jackson, David Gallo, Sushmetha Mohan, Frédéric Racicot, Trang Hoang, Brandon Ho, Amandine Bemmo, Frédéric Charron
المساهمون: Université de Montréal. Faculté de médecine. Département de médecine
المصدر: Nature Cancer
Tamayo Orrego, L, Gallo, D, Racicot, F, Bemmo, A, Mohan, S, Ho, B, Salameh, S, Hoang, T, Jackson, A P, Brown, G W & Charron, F 2020, ' Sonic hedgehog accelerates DNA replication to cause replication stress promoting cancer initiation in medulloblastoma ', nature cancer . https://doi.org/10.1038/s43018-020-0094-7Testمصطلحات موضوعية: DNA Replication, Cancer Research, animal structures, Carcinogenesis, Tumor initiation, Biology, medicine.disease_cause, Loss of heterozygosity, Mice, 03 medical and health sciences, 0302 clinical medicine, medicine, Animals, Hedgehog Proteins, Homologous recombination, Sonic hedgehog, Cancer models, Cerebellar Neoplasms, Cancer, 030304 developmental biology, Medulloblastoma, 0303 health sciences, DNA replication, Origin firing, medicine.disease, Cell biology, CNS cancer, Oncology, PTCH1, embryonic structures, biology.protein, 030217 neurology & neurosurgery
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e4d4c4af099fd7b9ffa5fbc117c5f4aTest
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المؤلفون: Frédéric Charron, Lukas Tamayo-Orrego
المصدر: F1000Research
مصطلحات موضوعية: tumor progression, Tumor initiation, Review, General Biochemistry, Genetics and Molecular Biology, law.invention, Metastasis, 03 medical and health sciences, Mice, 0302 clinical medicine, law, Cerebellum, medicine, Tumor Microenvironment, Animals, Humans, Hedgehog Proteins, General Pharmacology, Toxicology and Pharmaceutics, Sonic hedgehog, Cerebellar Neoplasms, neoplasms, 030304 developmental biology, Progenitor, Medulloblastoma, 0303 health sciences, Tumor microenvironment, General Immunology and Microbiology, biology, business.industry, General Medicine, Articles, medicine.disease, 3. Good health, nervous system diseases, stomatognathic diseases, Tumor progression, cell senescence, 030220 oncology & carcinogenesis, Cancer research, biology.protein, Suppressor, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5755cf5c04b15270443ab6d7369e74dTest
https://pubmed.ncbi.nlm.nih.gov/31700613Test -
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المؤلفون: Patricia T. Yam, Frédéric Charron
المصدر: Nature Chemical Biology. 15:1030-1031
مصطلحات موضوعية: 0303 health sciences, Mechanism (biology), Chemistry, 030302 biochemistry & molecular biology, Cell Biology, Endocytosis, Axon growth, Cell biology, 03 medical and health sciences, nervous system, Extracellular, Phosphorylation, Axon guidance, Receptor, Molecular Biology, 030304 developmental biology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::7f77bf6b0060fa881616bc3af854bbbeTest
https://doi.org/10.1038/s41589-019-0383-6Test -
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المؤلفون: Frédéric Charron, Elisabeth Traiffort, Amina Zahaf, Mary Zakaria, Olivier Pascual, Abdelmoumen Kassoussi, Ines Hristovska, Yousra Laouarem, Marie-Eve Mayeur, Julien Ferent
المصدر: Development. 146
مصطلحات موضوعية: Male, Neurofilament, Blotting, Western, Intermediate Filaments, Receptors, Cell Surface, Cuprizone, Mice, 03 medical and health sciences, Myelin, 0302 clinical medicine, medicine, Animals, Hedgehog Proteins, Axon, Sonic hedgehog, Molecular Biology, Cells, Cultured, Myelin Sheath, 030304 developmental biology, Mice, Knockout, 0303 health sciences, Microglia, biology, Macrophages, Cell Differentiation, Oligodendrocyte, Hedgehog signaling pathway, Myelin basic protein, Cell biology, Mice, Inbred C57BL, Oligodendroglia, medicine.anatomical_structure, nervous system, Immunoglobulin G, biology.protein, 030217 neurology & neurosurgery, Demyelinating Diseases, Developmental Biology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d4f6b00578939dbfbea779b59e7c2a5Test
https://doi.org/10.1242/dev.172502Test -
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المؤلفون: Frédéric Charron, Patricia T. Yam
المصدر: Current Opinion in Neurobiology. 23:965-973
مصطلحات موضوعية: Nervous system, animal structures, Neurogenesis, Cell fate determination, 03 medical and health sciences, 0302 clinical medicine, medicine, Animals, Humans, Hedgehog Proteins, Sonic hedgehog, Growth cone, Hedgehog, 030304 developmental biology, 0303 health sciences, biology, General Neuroscience, Wnt signaling pathway, Axons, Wnt Proteins, medicine.anatomical_structure, nervous system, Bone Morphogenetic Proteins, embryonic structures, biology.protein, Axon guidance, Signal transduction, Neuroscience, 030217 neurology & neurosurgery, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ed6f1e68d5e9c3fa9d162cb91bc9955Test
https://doi.org/10.1016/j.conb.2013.09.002Test -
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المؤلفون: Frédéric Charron, Won Jong Oh, Ellen Knevels, Geraldine Strasser, Liesbeth Aerts, Chengua Gu, Cathy Coulon, Patrick C.G. Haddick, Stefan Vinckier, Kari Alitalo, Jody J. Haigh, Coralie Fouquet, Valérie Castellani, Marc Tessier-Lavigne, Peter Carmeliet, Pierre J. Fabre, Inmaculada Segura, Nicolas Delattin, Alain Chédotal, Carmen Ruiz de Almodovar, Christian Lange
المصدر: Neuron. 70(5):966-978
مصطلحات موضوعية: 0303 health sciences, General Neuroscience, Neuroscience(all), Kinase insert domain receptor, Biology, Slit, 03 medical and health sciences, 0302 clinical medicine, medicine.anatomical_structure, nervous system, Netrin, medicine, biology.protein, Axon guidance, Axon, Sonic hedgehog, Growth cone, Neuroscience, 030217 neurology & neurosurgery, 030304 developmental biology, Floor plate
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3761408afd3ee4e825bd10ce0dbd5cbTest
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المؤلفون: Frédéric Charron, Cecilia Flores, Nicholas Meti, Angélica Torres-Berrío, Lauren Adye-White, Martin Lévesque, Véronique Rioux, Alanna Grant, Michael Verwey
المصدر: eNeuro
مصطلحات موضوعية: Male, Tyrosine 3-Monooxygenase, Dopamine, Neurogenesis, ventral tegmental area, Prefrontal Cortex, Substantia nigra, Motor Activity, Midbrain, sonic hedgehog, 03 medical and health sciences, 0302 clinical medicine, Neural Stem Cells, medicine, Cdon, Animals, Sonic hedgehog, Amphetamine, Pars Compacta, 030304 developmental biology, Mice, Knockout, 0303 health sciences, Tyrosine hydroxylase, biology, Pars compacta, Dopaminergic Neurons, General Neuroscience, General Medicine, New Research, Sensory Gating, Mice, Inbred C57BL, Ventral tegmental area, Phenotype, medicine.anatomical_structure, Cognition and Behavior, Animals, Newborn, nervous system, biology.protein, Central Nervous System Stimulants, Female, Cell Adhesion Molecules, Neuroscience, medial prefrontal cortex, 030217 neurology & neurosurgery, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bc1929bc578b5b117499dd2976ceb74Test
https://doi.org/10.1523/eneuro.0009-16.2016Test -
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المؤلفون: Andrew P. McMahon, Irene W. Althaus, Benjamin L. Allen, Jane Y. Song, Luisa Izzi, Frédéric Charron, Jong-Sun Kang, Robert S. Krauss
المصدر: Developmental cell. 20(6)
مصطلحات موضوعية: Patched, Kruppel-Like Transcription Factors, Fluorescent Antibody Technique, Cell Cycle Proteins, Receptors, Cell Surface, Chick Embryo, Biology, Zinc Finger Protein Gli2, GPI-Linked Proteins, Nervous System, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Mice, 0302 clinical medicine, medicine, Animals, Hedgehog Proteins, Cell Cycle Protein, Muscle, Skeletal, Molecular Biology, Hedgehog, In Situ Hybridization, 030304 developmental biology, Progenitor, Body Patterning, Genetics, Mice, Knockout, Neurons, 0303 health sciences, Neural tube, Extremities, Cell Biology, Embryo, Mammalian, Cell biology, Mice, Inbred C57BL, medicine.anatomical_structure, PTCH1, Immunoglobulin G, Signal transduction, Cell Adhesion Molecules, 030217 neurology & neurosurgery, Function (biology), Developmental Biology, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8a75abfbacef37354575de4bed71f5aTest
https://pubmed.ncbi.nlm.nih.gov/21664576Test -
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المؤلفون: Ko Currie, Alain Labbé, Frédéric Charron, Donald J van Meyel, Darius Camp
المصدر: Neural Development, Vol 5, Iss 1, p 28 (2010)
Neural Developmentمصطلحات موضوعية: Cellular differentiation, Receptors, Cell Surface, Biology, lcsh:RC346-429, 03 medical and health sciences, 0302 clinical medicine, Developmental Neuroscience, Compartment (development), Animals, Drosophila Proteins, Hedgehog Proteins, Hedgehog, lcsh:Neurology. Diseases of the nervous system, 030304 developmental biology, Genetics, Neurons, 0303 health sciences, Membrane Glycoproteins, Brain, Gene Expression Regulation, Developmental, Cell Differentiation, Hedgehog signaling pathway, Cell biology, DNA-Binding Proteins, Imaginal disc, Mutation, Eye development, Drosophila, Smoothened, 030217 neurology & neurosurgery, Morphogen, Signal Transduction, Transcription Factors, Research Article
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cd36a424ab0a3f910f90370f253ef7eTest
http://www.neuraldevelopment.com/content/5/1/28Test -
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المؤلفون: Mikhail Bashkurov, Gagan D. Gupta, Zachary Pincus, Frédéric Charron, Laurence Pelletier, David R. Colman, Patricia T. Yam
المصدر: PLoS ONE, Vol 8, Iss 11, p e79679 (2013)
PLoS ONEمصطلحات موضوعية: Time Factors, Synaptic cleft, Synaptogenesis, Neural facilitation, lcsh:Medicine, Biology, Hippocampus, Rats, Sprague-Dawley, 03 medical and health sciences, 0302 clinical medicine, Pregnancy, Synaptic augmentation, Animals, Active zone, lcsh:Science, 030304 developmental biology, Neurons, Microscopy, 0303 health sciences, Multidisciplinary, Synaptic pharmacology, lcsh:R, Anatomy, Cadherins, Rats, Protein Transport, Synaptic fatigue, Synapses, Silent synapse, Female, lcsh:Q, Neuroscience, 030217 neurology & neurosurgery, Research Article
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bbfe19d3a91eeb0f164b53b96424ca0Test
https://doi.org/10.1371/journal.pone.0079679Test