نتائج البحث - "Fernando Macian"

1

Age-associated changes in human CD4+ T cells point to mitochondrial dysfunction consequent to impaired autophagy

المؤلفون: Amit Singh, Christopher A. Dunn, Fernando Macian, Marta Gonzalez-Freire, Arsun Bektas, Luigi Ferrucci, Ana Maria Cuervo, Shepherd H. Schurman, Ranjan Sen

المصدر: Aging. 11:9234-9263

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::44e40c8177656843f62e63f8ce48bd01Test
https://doi.org/10.18632/aging.102438Test

2

H1 histones control the epigenetic landscape by local chromatin compaction

المصدر: Nature

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4851ae9d104cc9b8e0ee822e8581f22dTest
https://europepmc.org/articles/PMC8110206Test/

3

Glioblastoma ablates pericytes antitumor immune function through aberrant up-regulation of chaperone-mediated autophagy

المؤلفون: Salvador Martinez, José M. Moraleda, Ana Maria Cuervo, Ruth Valdor, Dolores Riquelme, David García-Bernal, Fernando Macian, Carlos Martinez

المساهمون: Ministerio de Economía y Competitividad (España), European Commission, Fundación Séneca, Instituto de Salud Carlos III

المصدر: Digital.CSIC. Repositorio Institucional del CSIC
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Proceedings of the National Academy of Sciences of the United States of America

مصطلحات موضوعية: immunosuppressive function, Programmed cell death, tumor, Chaperone-mediated autophagy, T cell, Cell, Apoptosis, Chaperone-Mediated Autophagy, Immunosuppressive function, pericytes, 03 medical and health sciences, Mice, 0302 clinical medicine, Immune system, Immunology and Inflammation, medicine, Tumor Cells, Cultured, Animals, Humans, health care economics and organizations, 030304 developmental biology, Cell Proliferation, 0303 health sciences, Multidisciplinary, Tumor, Chemistry, Autophagy, glioblastoma, Biological Sciences, Xenograft Model Antitumor Assays, humanities, 3. Good health, Cell biology, Mice, Inbred C57BL, medicine.anatomical_structure, PNAS Plus, Tumor progression, Cancer cell, Glioblastoma, Pericytes, 030217 neurology & neurosurgery, Molecular Chaperones

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ed2b8d1effa8038dfc4eebbe61d5e1eTest
http://hdl.handle.net/10261/217838Test

4

Chaperone-mediated autophagy regulates T cell responses through targeted degradation of negative regulators of T cell activation

المؤلفون: Ignacio Guerrero-Ros, Fernando Macian, Dinesh Chandra, Yair Botbol, Ana Maria Cuervo, Enric Mocholi, Hiroshi Koga, Claudia Gravekamp, Rut Valdor

المصدر: Nature immunology

مصطلحات موضوعية: Aging, Muscle Proteins, Basic helix-loop-helix leucine zipper transcription factors, Lymphocyte Activation, Mice, 0302 clinical medicine, Chaperone-mediated autophagy, RNA interference, Immunology and Allergy, Listeriosis, RNA, Small Interfering, health care economics and organizations, Cells, Cultured, Mice, Knockout, 0303 health sciences, Basic Helix-Loop-Helix Leucine Zipper Transcription Factors, Intracellular Signaling Peptides and Proteins, Dual Oxidases, humanities, Cell biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Female, RNA Interference, Ubiquitin-Protein Ligases, T cell, Calcineurin Inhibitors, Immunology, Receptors, Antigen, T-Cell, Biology, Article, 03 medical and health sciences, Lysosomal-Associated Membrane Protein 2, Autophagy, medicine, Animals, Humans, RNA, Messenger, 030304 developmental biology, Calcium-Binding Proteins, T-cell receptor, NADPH Oxidases, Th1 Cells, Listeria monocytogenes, Mice, Inbred C57BL, Calcineurin, Oxidative Stress, Cytoplasm, Immunization, Reactive Oxygen Species, Molecular Chaperones

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78af166c1f184bdfacbb4a4b093ed990Test
https://doi.org/10.1038/ni.3003Test

5

Age-Related Oxidative Stress Compromises Endosomal Proteostasis

المؤلفون: Fernando Macian, Ranjit Sahu, Susmita Kaushik, Carlo Follo, Laura Santambrogio, Kateryna Morozova, Ana Maria Cuervo, Elvira S. Cannizzo, Cristina C. Clement, Larissa N. Almeida, Rut Valdor

المصدر: Cell Reports, Vol 2, Iss 1, Pp 136-149 (2012)

مصطلحات موضوعية: Glycation End Products, Advanced, Aging, Endosomes, Biology, medicine.disease_cause, Models, Biological, Article, General Biochemistry, Genetics and Molecular Biology, Lymphatic System, Lipid peroxidation, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Immune system, Antigen, Glycation, medicine, Animals, Homeostasis, lcsh:QH301-705.5, Cells, Cultured, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Reactive oxygen species, Proteins, Dendritic Cells, Acquired immune system, Cell biology, Mice, Inbred C57BL, Oxidative Stress, Proteostasis, lcsh:Biology (General), chemistry, Biochemistry, 030220 oncology & carcinogenesis, Mice, Inbred CBA, Reactive Oxygen Species, Oxidation-Reduction, Protein Processing, Post-Translational, Oxidative stress

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca57af821e825f35e6051363d735a09dTest

6

Transcriptional complexes formed by NFAT dimers regulate the induction of T cell tolerance

المؤلفون: Brian T. Abe, Fernando Macian, Noemi Soto-Nieves, Anjana Rao, Ian Baine, Irene Puga, Sanmay Bandyopadhyay

المصدر: The Journal of Experimental Medicine

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6074cbc81182b09bda003cdc3f7c3214Test
https://doi.org/10.1084/jem.20082731Test

7

Transcriptional Mechanisms Underlying Lymphocyte Tolerance

المؤلفون: Fernando Macian, Anjana Rao, Sin-Hyeog Im, Michael C. Byrne, Heidi F. Horton, Francisco García-Cózar

المصدر: Cell. 109:719-731

مصطلحات موضوعية: Time Factors, Transcription, Genetic, T-Lymphocytes, Lymphocyte, Immunoblotting, Enzyme-Linked Immunosorbent Assay, Biology, Models, Biological, General Biochemistry, Genetics and Molecular Biology, Mice, 03 medical and health sciences, 0302 clinical medicine, Immune system, CD28 Antigens, medicine, Animals, Lymphocytes, Lymphocyte anergy, Transcription factor, Chelating Agents, 030304 developmental biology, Clonal Anergy, Mice, Inbred BALB C, 0303 health sciences, Cell Death, Dose-Response Relationship, Drug, NFATC Transcription Factors, Clonal anergy, Biochemistry, Genetics and Molecular Biology(all), Reverse Transcriptase Polymerase Chain Reaction, Calcineurin, Ionomycin, Nuclear Proteins, NFAT, Th1 Cells, Up-Regulation, Cell biology, DNA-Binding Proteins, Transcription Factor AP-1, Retroviridae, medicine.anatomical_structure, Cytokines, Calcium, Signal transduction, Cell Division, Signal Transduction, Transcription Factors, 030215 immunology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f91ea7b7314be5efa0fceb0b37553ea7Test
https://doi.org/10.1016/s0092-8674Test(02)00767-5

8

Ceacam1 Separates Graft-versus-Host-Disease from Graft-versus-Tumor Activity after Experimental Allogeneic Bone Marrow Transplantation

المصدر: PLoS ONE
PLoS ONE, Vol 6, Iss 7, p e21611 (2011)

مصطلحات موضوعية: Cytotoxicity, Immunologic, Cancer Research, Integrins, Graft vs Host Disease, lcsh:Medicine, CD8-Positive T-Lymphocytes, Lymphocyte Activation, Inflammatory bowel disease, Mice, 0302 clinical medicine, Carcinoembryonic antigen, immune system diseases, Radiation, Ionizing, Intestine, Small, Cytotoxic T cell, Bone Marrow and Stem Cell Transplantation, lcsh:Science, Immune Response, Bone Marrow Transplantation, 0303 health sciences, Multidisciplinary, biology, Cell adhesion molecule, T Cells, Graft vs Tumor Effect, Cell Polarity, Hematology, General Medicine, 3. Good health, Radiation Injuries, Experimental, surgical procedures, operative, Organ Specificity, 030220 oncology & carcinogenesis, Experimental pathology, Medicine, medicine.symptom, General Agricultural and Biological Sciences, Research Article, Tumor Immunology, Lymphoid Tissue, Immune Cells, Immunology, Inflammation, General Biochemistry, Genetics and Molecular Biology, Immunomodulation, 03 medical and health sciences, medicine, Animals, Humans, Transplantation, Homologous, Lymphocyte Count, Biology, 030304 developmental biology, Cell Proliferation, Transplantation, lcsh:R, Dendritic Cells, Immunologic Subspecialties, medicine.disease, Carcinoembryonic Antigen, Graft-versus-host disease, biology.protein, lcsh:Q

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0ab1cdb44e9ab41d505f41ce8cb0f5dTest

9

A photoconvertible fluorescent reporter to track chaperone-mediated autophagy

المؤلفون: Marta Martinez-Vicente, Vladislav V. Verkhusha, Fernando Macian, Ana Maria Cuervo, Hiroshi Koga

المصدر: Nature communications

مصطلحات موضوعية: General Physics and Astronomy, Molecular Probe Techniques, Biology, General Biochemistry, Genetics and Molecular Biology, Fluorescence, Article, Flow cytometry, 03 medical and health sciences, Mice, 0302 clinical medicine, Chaperone-mediated autophagy, Downregulation and upregulation, Cell Line, Tumor, medicine, Autophagy, Animals, Humans, health care economics and organizations, 030304 developmental biology, 0303 health sciences, Analysis of Variance, Multidisciplinary, medicine.diagnostic_test, General Chemistry, Flow Cytometry, In vitro, humanities, 3. Good health, Cell biology, Proteasome, Cell culture, NIH 3T3 Cells, Lysosomes, 030217 neurology & neurosurgery, Intracellular, Molecular Chaperones, Plasmids

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88a7e77e78a654c5553d4b6ccd9d7c34Test
https://pubmed.ncbi.nlm.nih.gov/21750540Test

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