نتائج البحث - "Ubiquitin-Protein Ligase"

1

Dun1, a Chk2-related kinase, is the central regulator of securin-separase dynamics during DNA damage signaling

المؤلفون: Idina Shi, Candice Qiu Xia Yam, Hong Hwa Lim, David Boy Chia, Uttam Surana

المصدر: Nucleic Acids Research

مصطلحات موضوعية: G2 Phase, Saccharomyces cerevisiae Proteins, Cell cycle checkpoint, DNA Repair, Transcription, Genetic, AcademicSubjects/SCI00010, DNA repair, DNA damage, Mitosis, Cell Cycle Proteins, Saccharomyces cerevisiae, Protein Serine-Threonine Kinases, Biology, Anaphase-Promoting Complex-Cyclosome, 03 medical and health sciences, Chromosome Segregation, Genetics, Molecular Biology, Separase, 030304 developmental biology, 0303 health sciences, Endosomal Sorting Complexes Required for Transport, 030302 biochemistry & molecular biology, Ubiquitin-Protein Ligase Complexes, Cell Cycle Checkpoints, G2-M DNA damage checkpoint, Cell biology, Securin, Checkpoint Kinase 2, Proteolysis, biological phenomena, cell phenomena, and immunity, Anaphase-promoting complex, Gene Deletion, DNA Damage, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e041a4167b7a1c58a41e492a7eaf456Test
https://doi.org/10.1093/nar/gkaa355Test

2

Defining the molecular basis of BubR1 kinetochore interactions and APC/C-CDC20 inhibition

المؤلفون: Tom L. Blundell, Sheena D'Arcy, Victor M. Bolanos-Garcia, Owen R. Davies

المساهمون: Blundell, Tom [0000-0002-2708-8992], Apollo - University of Cambridge Repository

المصدر: D'Arcy, S, Davies, O R, Blundell, T L & Bolanos-Garcia, V M 2010, ' Defining the molecular basis of BubR1 kinetochore interactions and APC/C-CDC20 inhibition ', Journal of Biological Chemistry, vol. 285, no. 19, pp. 14764-14776 . https://doi.org/10.1074/jbc.M109.082016Test
The Journal of Biological Chemistry

مصطلحات موضوعية: Cell/Checkpoint, Protein Conformation, Cell Cycle Proteins, Crystallography, X-Ray, Biochemistry, Microtubules, protein-protein interaction, 0302 clinical medicine, Protein structure, checkpoint, Organisms/Human, Kinetochores, Anaphase, Cancer, Genetics, 0303 health sciences, Kinetochore, Ubiquitin-Protein Ligase Complexes, Cell biology, Tetratricopeptide, Cell/Cycle, organisms, Crystallization, Microtubule-Associated Proteins, Signal Transduction, Protein/Structure, Cdc20 Proteins, Molecular Sequence Data, BUB1, CDC20, Biology, Protein Serine-Threonine Kinases, ubiquitination, Anaphase-Promoting Complex-Cyclosome, 03 medical and health sciences, Protein/Protein-Protein Interactions, Two-Hybrid System Techniques, cancer, Humans, Gene Regulation, human, Amino Acid Sequence, protein structure, Molecular Biology, Mitosis, 030304 developmental biology, Proteases/Ubiquitination, Sequence Homology, Amino Acid, Cell Biology, cell, Spindle apparatus, proteases, protein, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e72f1eb6c4143022c3f6ca5e6b3e43ceTest

3

GLI2 Modulated by SUFU and SPOP Induces Intestinal Stem Cell Niche Signals in Development and Tumorigenesis

المؤلفون: Tae-Hee Kim, Theodora Yung, Jingyi Pan, Sabrina Coquenlorge, Chi-chung Hui, Rong Mo, Xiaoyun Zhang, Wen-Chi Yin, Jaques Belik

المصدر: Cell Reports, Vol 27, Iss 10, Pp 3006-3018.e4 (2019)

مصطلحات موضوعية: Mesenchyme, Muscle Proteins, Biology, SPOP, Zinc Finger Protein Gli2, medicine.disease_cause, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Mice, 0302 clinical medicine, Transforming Growth Factor beta, GLI2, Intestine, Small, medicine, Animals, Hedgehog Proteins, Stem Cell Niche, Hedgehog, lcsh:QH301-705.5, 030304 developmental biology, Cell Proliferation, Mice, Knockout, 0303 health sciences, Muscles, Mesenchymal stem cell, Microfilament Proteins, Wnt signaling pathway, Ubiquitin-Protein Ligase Complexes, Fibroblasts, Embryo, Mammalian, Actins, Chromatin, Cell biology, Repressor Proteins, Wnt Proteins, medicine.anatomical_structure, Cell Transformation, Neoplastic, lcsh:Biology (General), Carcinogenesis, 030217 neurology & neurosurgery, Muscle Contraction, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04fd2bbfdaafcdf04fc833075008a531Test
http://www.sciencedirect.com/science/article/pii/S2211124719306278Test

4

Rsp5 Ubiquitin ligase–mediated quality control system clears membrane proteins mistargeted to the vacuole membrane

المؤلفون: Richa Sardana, Lu Zhu, Scott D. Emr

المصدر: The Journal of Cell Biology

مصطلحات موضوعية: Hot Temperature, Saccharomyces cerevisiae Proteins, macromolecular substances, Vacuole, Saccharomyces cerevisiae, Biology, Endocytosis, Article, Actin-Related Protein 2-3 Complex, 03 medical and health sciences, 0302 clinical medicine, Ubiquitin, Stress, Physiological, Gene Expression Regulation, Fungal, Organelle, Amino Acid Sequence, Research Articles, 030304 developmental biology, 0303 health sciences, Endosomal Sorting Complexes Required for Transport, Lysine, Cell Membrane, Ubiquitination, Ubiquitin-Protein Ligase Complexes, Cell Biology, Intracellular Membranes, Cell biology, Ubiquitin ligase, Adaptor Proteins, Vesicular Transport, Protein Transport, Membrane protein, Proteotoxicity, Proteolysis, Vacuoles, biology.protein, 030217 neurology & neurosurgery, Intracellular, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a21ac5801a59804757796e333bd1f645Test
http://europepmc.org/articles/PMC6314561Test

5

Targeting the RHOA pathway improves learning and memory in adult Kctd13 and 16p11.2 deletion mouse models

المؤلفون: Valérie Nalesso, Yann Herault, Sandra Martin Lorenzo, Marie-Christine Birling, Claire Chevalier

المساهمون: Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Institut Clinique de la Souris (ICS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA), Herault, Yann

المصدر: Molecular Autism, Vol 12, Iss 1, Pp 1-13 (2021)
Molecular Autism
Molecular Autism, BioMed Central, 2021, 12 (1), ⟨10.1186/s13229-020-00405-7⟩
Molecular Autism, 2021, 12 (1), ⟨10.1186/s13229-020-00405-7⟩

مصطلحات موضوعية: RHOA, Autism Spectrum Disorder, [SDV]Life Sciences [q-bio], Mutant, Neurodevelopment, Preclinical treatment, Intellectual disability, Chromosome Disorders, lcsh:RC346-429, Recognition memory, Exon, Mice, 0302 clinical medicine, Cognition, 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine, Copy-number variation, ComputingMilieux_MISCELLANEOUS, Genetics, Mice, Knockout, 0303 health sciences, rho-Associated Kinases, Fasudil, Ubiquitin-Protein Ligase Complexes, Autism spectrum disorders, Phenotype, Psychiatry and Mental health, Treatment Outcome, Chromosome Deletion, Signal Transduction, Locus (genetics), [SDV.GEN.GA] Life Sciences [q-bio]/Genetics/Animal genetics, Biology, Mouse model, 03 medical and health sciences, Developmental Neuroscience, Memory, Memory improvement, Animals, Learning, Genetic Predisposition to Disease, KCTD13, Autistic Disorder, Molecular Biology, Alleles, Genetic Association Studies, lcsh:Neurology. Diseases of the nervous system, 030304 developmental biology, Copy number variation, Research, [SCCO.NEUR]Cognitive science/Neuroscience, [SCCO.NEUR] Cognitive science/Neuroscience, Disease Models, Animal, [SDV.GEN.GA]Life Sciences [q-bio]/Genetics/Animal genetics, biology.protein, rhoA GTP-Binding Protein, 030217 neurology & neurosurgery, Chromosomes, Human, Pair 16, Developmental Biology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0383b4e45a1844d1ddfe41cff9a9bf23Test
https://doi.org/10.21203/rs.3.rs-60136/v1Test

6

Calcineurin-dependent regulation of endocytosis by a plasma membrane ubiquitin ligase adaptor, Rcr1

المؤلفون: Lu Zhu, Daniel K. Jin, Richa Sardana, Scott D. Emr

المصدر: The Journal of Cell Biology

مصطلحات موضوعية: Saccharomyces cerevisiae Proteins, Saccharomyces cerevisiae, macromolecular substances, Protein Sorting Signals, Biology, Endocytosis, Microbiology, 03 medical and health sciences, 0302 clinical medicine, Cell Signaling, Ubiquitin, Report, Gene Expression Regulation, Fungal, Genetics, 030304 developmental biology, Chitin Synthase, 0303 health sciences, Trafficking, Endosomal Sorting Complexes Required for Transport, Calcineurin, Ubiquitination, Membrane Proteins, Ubiquitin-Protein Ligase Complexes, Signal transducing adaptor protein, Cell Biology, Transmembrane protein, Ubiquitin ligase, Cell biology, DNA-Binding Proteins, Exomer complex, Proteolysis, biology.protein, 030217 neurology & neurosurgery, Nedd4 Ubiquitin Protein Ligases, Signal Transduction, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4a41df27fb76d91ae61269172427430Test
https://doi.org/10.1083/jcb.201909158Test

7

Rsp5-dependent endocytosis and degradation of the arsenite transporter Acr3 requires its N-terminal acidic tail as an endocytic sorting signal and arrestin-related ubiquitin-ligase adaptors

المؤلفون: Joanna Sadlak, Ewa Maciaszczyk-Dziubinska, Donata Wawrzycka, Robert W. Wysocki

المصدر: Biochimica et biophysica acta. Biomembranes. 1861(5)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1892e4c1eb4ee48ce22336af2f9f1dfTest
https://pubmed.ncbi.nlm.nih.gov/30776335Test

8

A molecular switch on an arrestin-like protein relays glucose signaling to transporter endocytosis

المؤلفون: Rosine Haguenauer-Tsapis, Jéssica Gomes-Rezende, Neide Vieira, Sandra Paiva, Michel Becuwe, Olivier Vincent, David Lara, Carina Soares-Cunha, Margarida Casal, Sébastien Léon

المساهمون: Universidade do Minho, Institut Jacques Monod (IJM (UMR_7592)), Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Department of Biology, Molecular and Environmental Biology Centre (CBMA), University of Minho [Braga], Instituto de Investigaciones Biomédicas CSIC-UAM, Instituto de Investigaciones Biomédicas, Centre National de la Recherche Scientifique (CNRS), Université Paris Diderot, Ligue Nationale Contre le Cancer (Comité de Paris, grant RS09/75-26), Marie Curie RTN: UBIREGULATORS, contract MRTN-CT-2006-034555), Association pour la Recherche sur le Cancer (ARC, grant SFI20101201844), Spanish CICYT (BFU2008-02005), the Comunidad de Madrid, CSIC (CCG08-CSIC/SAL-3611), French Ministère de l'Enseignement Supérieur et de la Recherche, Ubiquitine et trafic intracellulaire (Resp. Rosine Haguenauer-Tsapis), European Project: 32579,RUBICON

المصدر: The Journal of Cell Biology
Digital.CSIC. Repositorio Institucional del CSIC
instname
Journal of Cell Biology
Journal of Cell Biology, Rockefeller University Press, 2012, 196 (2), pp.247-59. ⟨10.1083/jcb.201109113⟩
Journal of Cell Biology, 2012, 196 (2), pp.247-59. ⟨10.1083/jcb.201109113⟩
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

مصطلحات موضوعية: Monocarboxylic Acid Transporters, Snf3, Saccharomyces cerevisiae Proteins, genetic structures, Green Fluorescent Proteins, ComputingMilieux_LEGALASPECTSOFCOMPUTING, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, macromolecular substances, Protein Serine-Threonine Kinases, Endocytosis, Article, 03 medical and health sciences, 0302 clinical medicine, Ubiquitin, Arrestin, ComputingMilieux_MISCELLANEOUS, Research Articles, 030304 developmental biology, 0303 health sciences, Science & Technology, biology, Endosomal Sorting Complexes Required for Transport, Symporters, Membrane transport protein, Glucose transporter, Ubiquitination, Membrane Proteins, Membrane Transport Proteins, Ubiquitin-Protein Ligase Complexes, Cell Biology, Protein-Serine-Threonine Kinases, 3. Good health, Cell biology, Ubiquitin ligase, Glucose, Data_GENERAL, biology.protein, sense organs, Signal transduction, Protein Processing, Post-Translational, 030217 neurology & neurosurgery, Signal Transduction

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12380390869f8ac014824f03e5c252c8Test
http://europepmc.org/articles/PMC3265958Test

9

Linear ubiquitination prevents inflammation and regulates immune signalling

المؤلفون: W. Wei-Lynn Wong, Holly Anderton, James A Rickard, Henning Walczak, Uwe Warnken, Björn Gerlach, John Silke, Ueli Nachbur, Anna C. Schmukle, Anthony W. Purcell, Eva Rieser, Stefanie M. Cordier, Christoph H. Emmerich, Lahiru Gangoda, Tobias L. Haas, Andrew I. Webb

المصدر: Nature

مصطلحات موضوعية: medicine.medical_treatment, Ubiquitin-Protein Ligases, CD40 Ligand, Interleukin-1beta, Inflammation, Nerve Tissue Proteins, Biology, Receptors, Tumor Necrosis Factor, Cell Line, 03 medical and health sciences, RIPK1, Mice, 0302 clinical medicine, Ubiquitin, Settore MED/04 - PATOLOGIA GENERALE, Receptors, IKBKG, medicine, Animals, Humans, SHARPIN Gene, 030304 developmental biology, Skin, 0303 health sciences, Multidisciplinary, Tumor Necrosis Factor-alpha, Immunity, NF-kappa B, Ubiquitination, Ubiquitin-Protein Ligase Complexes, 3. Good health, Cell biology, I-kappa B Kinase, Cytokine, Phenotype, 030220 oncology & carcinogenesis, Multiprotein Complexes, Receptor-Interacting Protein Serine-Threonine Kinases, biology.protein, Tumor necrosis factor alpha, medicine.symptom, Signal transduction, Tumor Necrosis Factor, Carrier Proteins, Transcription Factors, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc4aed2b8355b74b848256a10ac761b7Test

10

Oscillations in Cdc14 release and sequestration reveal a circuit underlying mitotic exit

المؤلفون: Fabrice Caudron, Rosella Visintin, Andrea Ciliberto, Francesca Montani, Romilde Manzoni, Clara Visintin

المصدر: The Journal of Cell Biology

مصطلحات موضوعية: Saccharomyces cerevisiae Proteins, Mitosis, Cell Cycle Proteins, Saccharomyces cerevisiae, Polo-like kinase, Cyclin B, Protein Serine-Threonine Kinases, Models, Biological, Article, Anaphase-Promoting Complex-Cyclosome, Cdh1 Proteins, 03 medical and health sciences, Cyclin-dependent kinase, Centrosome duplication, Research Articles, 030304 developmental biology, Anaphase, 0303 health sciences, Cyclin-dependent kinase 1, biology, Cdc14, 030302 biochemistry & molecular biology, Nuclear Proteins, Ubiquitin-Protein Ligase Complexes, Cell Biology, 3. Good health, Cell biology, Enzyme Activation, Mitotic exit, biology.protein, Protein Tyrosine Phosphatases, Protein Kinases, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d606fe0b54a381e82b0578f603d8e95bTest
https://doi.org/10.1083/jcb.201002026Test

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