نتائج البحث - "Type I interferon production"

1

G-quadruplex binders as cytostatic modulators of innate immune genes in cancer cells

المؤلفون: Marco Russo, Giovanni Capranico, Giulia Miglietta, Renée C. Duardo

المساهمون: Miglietta G., Russo M., Duardo R.C., Capranico G.

المصدر: Nucleic Acids Research

مصطلحات موضوعية: AcademicSubjects/SCI00010, Melanoma, Experimental, Micronuclei, Nucleotidyltransferase, Antineoplastic Agent, Mice, MCF-7 Cell, 0302 clinical medicine, Aminoquinoline, Interferon, Cytotoxic T cell, Picolinic Acids, Membrane Protein, Regulation of gene expression, 0303 health sciences, Fused-Ring Compounds, Nucleotidyltransferases, 030220 oncology & carcinogenesis, Aminoquinolines, MCF-7 Cells, Female, Signal transduction, Breast Neoplasm, Human, medicine.drug, Transcriptional Activation, Cytostatic Agent, Picolinic Acid, Antineoplastic Agents, Breast Neoplasms, Biology, Cell Line, 03 medical and health sciences, Chemical Biology and Nucleic Acid Chemistry, G-Quadruplexe, Genetics, medicine, Animals, Humans, Gene, Micronuclei, Chromosome-Defective, 030304 developmental biology, Innate immune system, Membrane Proteins, Interferon-beta, Type I interferon production, Cytostatic Agents, Fused-Ring Compound, Immunity, Innate, G-Quadruplexes, Cancer cell, Cancer research, Interferon Regulatory Factor-3

وصف الملف: STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46b20edeb20e0351eeb8d735154aa2edTest
http://europepmc.org/articles/PMC8266585Test

2

Decreased Type I Interferon Production by Plasmacytoid Dendritic Cells Contributes to Severe Dengue

المؤلفون: Denis R. St. Laurent, Darragh Duffy, Veasna Duong, Tineke Cantaert, Axelle Vanderlinden, Carolina Scagnolari, Nikaïa Smith, Vinit Upasani, Federica Frasca, Philippe Dussart, Vincent Bondet, Sokchea Lay, Guido Antonelli, Sothy Heng, Heidi Auerswald, Sowath Ly

المساهمون: Immunologie [Phnom Penh], Institut Pasteur du Cambodge, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), University of Groningen [Groningen], Department of Molecular Medicine, Institut Pasteur, Fondation Cenci Bolognetti - Istituto Pasteur Italia, Fondazione Cenci Bolognetti, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome] (UNIROMA), Réseau International des Instituts Pasteur (RIIP), Immunologie Translationnelle - Translational Immunology lab, Institut Pasteur [Paris] (IP), Kantha Bopha Hospitals Foundation, This study was supported by a grant from Institut Pasteur (ACIP n°221 -2019, DeSiReS: Dengue Severe Immune Response Studies). TC was funded by the Institute Pasteur International Network and is an HHMI-Wellcome Trust International Research Scholar (208710/Z/17/Z). VU was funded by the Institute Pasteur International Network Calmette and Yersin Ph.D. scholarship. DD acknowledges support from the Agence Nationale de la Recherche (ANR grant number CE17001002)., ANR-16-CE17-0005,GENMSMD,Dissection génétique de la Susceptibilité Mendélienne aux infections mycobactériennes chez l'homme(2016), ANR-16-CE17-0010,IFNX,Investigation des interferonopathies type I humaine(2016), Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome], Institut Pasteur [Paris]

المصدر: Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology
Frontiers in Immunology, 2020, 11, pp.605087. ⟨10.3389/fimmu.2020.605087⟩
Frontiers in Immunology, Frontiers, 2020, 11, pp.605087. ⟨10.3389/fimmu.2020.605087⟩
Frontiers in Immunology, 11:605087. Frontiers Media SA

مصطلحات موضوعية: Male, Time Factors, viruses, Plasmacytoid dendritic cell, Dengue virus, medicine.disease_cause, Antibodies, Viral, Severity of Illness Index, DISEASE, Dengue, 0302 clinical medicine, Immunology and Allergy, Platelet, Child, Original Research, 0303 health sciences, interferon stimulated genes, Antibody titer, virus diseases, simoa immunoassay, Viral Load, Acquired immune system, Prognosis, myloid dendritic cells, Single Molecule Imaging, 3. Good health, B-CELLS, Child, Preschool, Host-Pathogen Interactions, Interferon Type I, POSTTRANSCRIPTIONAL REGULATION, [SDV.IMM]Life Sciences [q-bio]/Immunology, type I interferon, Female, Cambodia, Viral load, lcsh:Immunologic diseases. Allergy, Adolescent, Immunology, Enzyme-Linked Immunosorbent Assay, RECEPTOR IFNAR-2, 03 medical and health sciences, Immune system, ENHANCEMENT, medicine, plasmacytoid dendritic cell, Humans, 030304 developmental biology, dengue virus, business.industry, Platelet Count, Dendritic Cells, biochemical phenomena, metabolism, and nutrition, Type I interferon production, Antibodies, Neutralizing, ALPHA, VIRUS-INFECTION REQUIRES, HEMORRHAGIC-FEVER, Case-Control Studies, IFN-BETA, business, lcsh:RC581-607, 030215 immunology, RESPONSES

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab42c88242b43c752954a404e305f0d5Test
http://hdl.handle.net/11573/1473176Test

3

NLRP12 regulates anti-viral RIG-I activation via interaction with TRIM25

المؤلفون: Chih Wei Chao, Jenny P.-Y. Ting, Yen Po Tsao, Ivan Dzhagalov, Liang Chen, Moon Jung Song, Hye Ri Kang, Diego Shih Chieh Lin, Szu Ting Chen, W. June Brickey, Fei Ju Li, Haitao Guo, Sei Yi Chen, Jae U. Jung, Jason W. Tam, Wei Ting Tseng

مصطلحات موضوعية: Male, TRIM25, viruses, chemical and pharmacologic phenomena, Microbiology, Article, 03 medical and health sciences, Mice, 0302 clinical medicine, RNA Virus Infections, Ubiquitin, Interferon, Virology, medicine, Animals, Humans, RNA Viruses, 030304 developmental biology, 0303 health sciences, Innate immune system, biology, RIG-I, Intracellular Signaling Peptides and Proteins, Ubiquitination, virus diseases, biochemical phenomena, metabolism, and nutrition, Type I interferon production, biology.organism_classification, Ubiquitin ligase, Cell biology, DNA-Binding Proteins, Mice, Inbred C57BL, Vesicular stomatitis virus, biology.protein, DEAD Box Protein 58, Parasitology, Female, Interferons, biological phenomena, cell phenomena, and immunity, 030217 neurology & neurosurgery, medicine.drug, Protein Binding, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ae67987f1a9c1ebef8b0976aa36bddcTest
https://europepmc.org/articles/PMC6459718Test/

4

Bronchial mucosal IFN-α/β and pattern recognition receptor expression in patients with experimental rhinovirus-induced asthma exacerbations

المؤلفون: Onn Min Kon, Alberto Papi, Luminita A. Stanciu, Jie Zhu, Christine K. Ward, Marco Contoli, Simon D. Message, Mary Ann Mascelli, Michael R. Edwards, Peter K. Jeffery, Elliot S. Barnathan, Tatiana Kebadze, Sebastian L. Johnston, Patrick Mallia

المصدر: The Journal of Allergy and Clinical Immunology

مصطلحات موضوعية: Male, Allergy, Interferon-Induced Helicase, IFIH1, Rhinovirus, AHR, Airway hyperresponsiveness, Biopsy, medicine.disease_cause, Severity of Illness Index, MDA5, Melanoma differentiation–associated gene 5, 0302 clinical medicine, rhinovirus infection, Interferon, Asthma exacerbation, rhinovirus infection, type I interferon, pattern recognition receptors, Immunology and Allergy, Receptors, Immunologic, 0303 health sciences, Toll-like receptor, virus diseases, RV16, Rhinovirus 16, respiratory system, 3. Good health, DEAD Box Protein 58, type I interferon, Female, Viral load, TLR, Toll-like receptor, medicine.drug, Adult, HRP, Horseradish peroxidase, PRR, Pattern recognition receptor, BAL, Bronchoalveolar lavage, Asthma exacerbation, Immunology, Alpha interferon, Socio-culturale, Bronchi, Article, RIG-I, Retinoic acid–inducible protein I, 03 medical and health sciences, Immune system, PEF, Peak expiratory flow, medicine, Humans, 030304 developmental biology, Picornaviridae Infections, business.industry, pattern recognition receptors, Interferon-alpha, Interferon-beta, medicine.disease, Type I interferon production, Asthma, Toll-Like Receptor 3, respiratory tract diseases, Gene Expression Regulation, business, 030215 immunology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b155e0565de09a673f8091ddc072c443Test
http://hdl.handle.net/11392/2397435Test

5

Apoptotic Caspases Suppress Type I Interferon Production via the Cleavage of cGAS, MAVS, and IRF3

المؤلفون: Mengze Lv, Ji-Ming Feng, Pengfei Gao, Miao Jing, Xiaohan Ning, Rui Zhang, Zhengfan Jiang, Yutao Wang, Mengyin Sha, Xiao-Jun Huang

المصدر: Molecular cell. 74(1)

مصطلحات موضوعية: Male, THP-1 Cells, medicine.medical_treatment, Apoptosis, Vaccinia virus, Sendai virus, 03 medical and health sciences, 0302 clinical medicine, medicine, Animals, Humans, Molecular Biology, Caspase, 030304 developmental biology, Adaptor Proteins, Signal Transducing, Caspase 7, 0303 health sciences, Innate immune system, biology, Caspase 3, Experimental autoimmune encephalomyelitis, Caspase 2, Inflammasome, Cell Biology, Type I interferon production, medicine.disease, Nucleotidyltransferases, Caspase 9, Immunity, Innate, Cell biology, Mice, Inbred C57BL, Cytokine, HEK293 Cells, Virus Diseases, Caspases, Host-Pathogen Interactions, Interferon Type I, biology.protein, Female, Interferon Regulatory Factor-3, IRF3, 030217 neurology & neurosurgery, medicine.drug, HeLa Cells, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8771fc176735437bf309de0612d1ed86Test
https://pubmed.ncbi.nlm.nih.gov/30878284Test

6

Wiskott-Aldrich syndrome protein-mediated actin dynamics control type-I interferon production in plasmacytoid dendritic cells

المؤلفون: Elisa Bonomi, Ulrich Kalinke, Stefania Gobessi, Anna Villa, Marco Catucci, Ayse Metin, Luigi D. Notarangelo, Francesca Prete, Sophie Hambleton, Maria Carmina Castiello, William Vermi, Robbert G. M. Bredius, Mayrel Labrada, Mirjam van der Burg, Federica Benvenuti, Caterina Cancrini, Alessandro Aiuti

المساهمون: Immunology, International Centre for Genetic Engineering and Biotechnology, Padriciano 99, 34149 Trieste, Italy., Prete, Francesca, Catucci, Marco, Labrada, Mayrel, Gobessi, Stefania, Castiello Maria, Carmina, Bonomi, Elisa, Aiuti, Alessandro, Vermi, William, Cancrini, Caterina, Metin, Ayse, Hambleton, Sophie, Bredius, Robbert, Notarangelo Luigi, Daniele, van der Burg, Mirjam, Kalinke, Ulrich, Villa, Anna, Benvenuti, Federica

المصدر: Journal of Experimental Medicine, 210(2), 355-374. Rockefeller University Press
The Journal of Experimental Medicine

مصطلحات موضوعية: Male, Wiskott–Aldrich syndrome, Autoimmunity, Plasmacytoid dendritic cell, Receptor, Interferon alpha-beta, Mice, 0302 clinical medicine, immune system diseases, Interferon, hemic and lymphatic diseases, Immunology and Allergy, Mice, Knockout, 0303 health sciences, biology, Wiskott–Aldrich syndrome protein, hemic and immune systems, Endocytosis, Cell biology, Wiskott-Aldrich Syndrome, 3. Good health, Interferon Type I, Female, Wiskott-Aldrich Syndrome Protein, medicine.drug, Signal Transduction, congenital, hereditary, and neonatal diseases and abnormalities, Immunology, macromolecular substances, Article, 03 medical and health sciences, medicine, Animals, Humans, RNA, Messenger, 030304 developmental biology, Innate immune system, Base Sequence, TLR9, Interferon-alpha, Dendritic Cells, Cell Biology, medicine.disease, Type I interferon production, Actins, Immunity, Innate, Mice, Inbred C57BL, Disease Models, Animal, Toll-Like Receptor 9, biology.protein, Interferon type I, 030215 immunology