نتائج البحث - "Sequestosome-1"

المساهمون: Centre méditerranéen de médecine moléculaire (C3M), Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Côte d'Azur (UCA), Centre Scientifique de Monaco (CSM), Institut de pharmacologie moléculaire et cellulaire (IPMC), Centre National de la Recherche Scientifique (CNRS)-Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA), Université Côte d'Azur (UCA), Centre National de la Recherche Scientifique (CNRS), ANR-18-CE14-0025,MatriPHate,Comprendre la dynamique de la niche vasculaire dans l'hypertension pulmonaire.(2018), Centre Hospitalier Universitaire de Nice (CHU Nice), Imperial College London, University of Gothenburg (GU), Université Nice Sophia Antipolis (1965 - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Centre National de la Recherche Scientifique (CNRS)-Université Côte d'Azur (UCA), Bertero, Thomas, Bost, Frédéric

المصدر: eLife
eLife, eLife Sciences Publication, 2021, 10, ⟨10.7554/elife.68348⟩
eLife, eLife Sciences Publication, 2021, 10, ⟨10.7554/eLife.68348⟩
eLife, 2021, 10, ⟨10.7554/elife.68348⟩
eLife, Vol 10 (2021)
eLife, 2021, 10, ⟨10.7554/eLife.68348⟩

مصطلحات موضوعية: Male, Acid Ceramidase, [SDV]Life Sciences [q-bio], [SDV.BC.BC]Life Sciences [q-bio]/Cellular Biology/Subcellular Processes [q-bio.SC], chemistry.chemical_compound, 0302 clinical medicine, Ubiquitin, Sequestosome-1 Protein, cell biology, Epidermal growth factor receptor, Biology (General), Phosphorylation, 0303 health sciences, education.field_of_study, biology, Neoplasm Proteins, Cell biology, ErbB Receptors, Gene Expression Regulation, Neoplastic, 030220 oncology & carcinogenesis, Medicine, Signal transduction, Signal Transduction, Ceramide, QH301-705.5, Science, EGFR, [SDV.CAN]Life Sciences [q-bio]/Cancer, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, Ceramides, ubiquitination, Gene Expression Regulation, Enzymologic, UBTD1, 03 medical and health sciences, Sequestosome 1, [SDV.CAN] Life Sciences [q-bio]/Cancer, Cell Line, Tumor, [SDV.BC.BC] Life Sciences [q-bio]/Cellular Biology/Subcellular Processes [q-bio.SC], Humans, ceramide, human, education, [SDV.BC] Life Sciences [q-bio]/Cellular Biology, Ubiquitins, 030304 developmental biology, Cell growth, Prostatic Neoplasms, Endolysosome, Kinetics, cell proliferation, chemistry, Proteolysis, biology.protein, Lysosomes

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c063746d57ffb3738310b2b4cb7ce585Test
https://hal.archives-ouvertes.fr/hal-03408303/file/elife-68348-v2.pdfTest

6

Effect of rapamycin on mitochondria and lysosomes in fibroblasts from patients with mtDNA mutations

المؤلفون: Jessie M. Cameron, Nashwa Cheema, David A. Hood

مصطلحات موضوعية: Male, 0301 basic medicine, Physiology, Mitochondrion, Mitochondrial Membrane Transport Proteins, Oxidative Phosphorylation, Basal (phylogenetics), 0302 clinical medicine, Mitochondrial myopathy, Mitochondrial Precursor Protein Import Complex Proteins, Sequestosome-1 Protein, MELAS Syndrome, Membrane Potential, Mitochondrial, 0303 health sciences, Mitochondria, Cell biology, 3. Good health, medicine.anatomical_structure, Child, Preschool, Lactic acidosis, Female, Vacuolar Proton-Translocating ATPases, medicine.medical_specialty, Mitochondrial DNA, Primary Cell Culture, Motility, Biology, DNA, Mitochondrial, Young Adult, 03 medical and health sciences, Internal medicine, Lysosome, Respiration, medicine, Humans, 030304 developmental biology, Sirolimus, Superoxide Dismutase, Infant, Cell Biology, Fibroblasts, medicine.disease, Mtdna mutations, 030104 developmental biology, Endocrinology, Gene Expression Regulation, Cell culture, Case-Control Studies, Mutation, Lysosomes, Function (biology), 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::484b55d405042647176fb62c6b5ce4bcTest
https://doi.org/10.1101/2021.03.31.437507Test

7

Elongation factor eEF2 kinase and autophagy jointly promote survival of cancer cells

المؤلفون: Danielle Meiwen Fang, Christopher G. Proud, Xuemin Wang, Roman V. Lenchine, Sushma R Rao

المصدر: The Biochemical journal. 478(8)

مصطلحات موضوعية: Elongation Factor 2 Kinase, Proteomics, Proteome, Cell Survival, Glutamine, mTORC1, Biology, EEF2, Biochemistry, 03 medical and health sciences, 0302 clinical medicine, Cell Line, Tumor, Pyruvic Acid, Sequestosome-1 Protein, Autophagy, Humans, education, Protein kinase A, Molecular Biology, 030304 developmental biology, 0303 health sciences, education.field_of_study, Kinase, Cell Biology, Phosphoproteins, Cell biology, Elongation factor, Gene Expression Regulation, Neoplastic, Glucose, A549 Cells, 030220 oncology & carcinogenesis, Protein Biosynthesis, Cancer cell, PC-3 Cells, Elongation Factor-2 Kinase, Macrolides, Energy Metabolism, Microtubule-Associated Proteins, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dbfbefd401fe9014bde321d3e8cb936Test
https://pubmed.ncbi.nlm.nih.gov/33779695Test

8

Inflammatory and Senescent Phenotype of Pancreatic Stellate Cells Induced by Sqstm1 Downregulation Facilitates Pancreatic Cancer Progression

المؤلفون: Xiangdong Cheng, Kequn Chai, Chaoyong Tu, Xiaoguang Wang, Zhiyuan Xu, Wei Chen, Jian Shen, Chuxiao Shao

المصدر: International Journal of Biological Sciences

مصطلحات موضوعية: senescence, Chemokine CXCL1, Chemokine CXCL2, Immunoblotting, Fluorescent Antibody Technique, Mice, Nude, pancreatic stellate cells, Biology, Real-Time Polymerase Chain Reaction, Applied Microbiology and Biotechnology, Small hairpin RNA, Mice, 03 medical and health sciences, Downregulation and upregulation, Pancreatic tumor, Cell Line, Tumor, Pancreatic cancer, Sequestosome-1 Protein, pancreatic adenocarcinoma, medicine, Animals, Humans, RNA, Small Interfering, Molecular Biology, Ecology, Evolution, Behavior and Systematics, 030304 developmental biology, reactive oxygen species, Mice, Inbred BALB C, 0303 health sciences, Cell growth, Interleukin-8, Cell Biology, medicine.disease, Immunohistochemistry, Phenotype, sqstm1, Pancreatic Neoplasms, CXCL1, Cancer research, Hepatic stellate cell, Female, Carcinoma, Pancreatic Ductal, Research Paper, Developmental Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c101624302bbada35aece440ff7b34fTest
https://doi.org/10.7150/ijbs.27825Test

9

Gαq activation modulates autophagy by promoting mTORC1 signaling

المؤلفون: Anna M. Aragay, Elena Rebollo, Antonio Diaz, Inmaculada Tasset, Alvaro Caballero, Federico Mayor, Maria Sanz-Flores, Ana Maria Cuervo, Sofía Cabezudo, Catalina Ribas

المساهمون: UAM. Departamento de Biología Molecular, Ministerio de Economía y Competitividad (España), Instituto de Salud Carlos III, Fundación Ramón Areces, Comunidad de Madrid, National Institutes of Health (US), EMBO, Ministerio de Economía, Industria y Competitividad (España), Unión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF)

المصدر: Biblos-e Archivo. Repositorio Institucional de la UAM
instname
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Digital.CSIC. Repositorio Institucional del CSIC

مصطلحات موضوعية: Male, Kinase 2, General Physics and Astronomy, Cellular homeostasis, Network, mTORC1, Growth, Protein-Coupled Receptors, Mice, 0302 clinical medicine, G protein-coupled receptors, Sequestosome-1 Protein, 0303 health sciences, Multidisciplinary, Trafficking, biology, Effector, Chemistry, Biología y Biomedicina / Biología, Cell biology, Phenotype, Gq alpha subunit, Liver, Signal transduction, biological phenomena, cell phenomena, and immunity, Protein Binding, Signal Transduction, Science, CHO Cells, Mechanistic Target of Rapamycin Complex 1, Models, Biological, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Cricetulus, Protein Domains, Complex, Macroautophagy, Autophagy, Animals, Humans, Rats, Wistar, 030304 developmental biology, G protein-coupled receptor, General Chemistry, Regulatory-Associated Protein of mTOR, Nutrient signalling, Fibroblasts, HEK293 Cells, Metabolism, Vacuoles, biology.protein, GTP-Binding Protein alpha Subunits, Gq-G11, Lysosomes, 030217 neurology & neurosurgery, Pathway

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d50a57cfc4efa04aa0b16c49adcdbacTest
http://hdl.handle.net/10486/702267Test

10

The CDT of Helicobacter hepaticus induces pro-survival autophagy and nucleoplasmic reticulum formation concentrating the RNA binding proteins UNR/CSDE1 and P62/SQSTM1

المؤلفون: Pierre Dubus, Armelle Ménard, Lamia Azzi-Martin, Philippe Lehours, Wencan He, Valérie Velasco, Mojgan Djavaheri-Mergny

المساهمون: Gestionnaire, Hal Sorbonne Université, Bordeaux Research In Translational Oncology [Bordeaux] (BaRITOn), Université de Bordeaux (UB)-CHU Bordeaux [Bordeaux]-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Bergonié [Bordeaux], UNICANCER, CHU Bordeaux [Bordeaux], Centre de Recherche des Cordeliers (CRC (UMR_S_1138 / U1138)), École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Université Paris Cité (UPCité), Institut Universitaire de France (IUF), Ministère de l'Education nationale, de l’Enseignement supérieur et de la Recherche (M.E.N.E.S.R.), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Université de Paris (UP)

المصدر: PLoS Pathogens
PLoS Pathogens, 2021, 17 (3), pp.e1009320. ⟨10.1371/journal.ppat.1009320⟩
PLoS Pathogens, Public Library of Science, 2021, 17 (3), pp.e1009320. ⟨10.1371/journal.ppat.1009320⟩
PLoS Pathogens, Vol 17, Iss 3, p e1009320 (2021)

مصطلحات موضوعية: [SDV]Life Sciences [q-bio], Apoptosis, Biochemistry, 0302 clinical medicine, Sequestosome-1 Protein, Medicine and Health Sciences, Public and Occupational Health, Biology (General), Staining, 0303 health sciences, Cell Death, biology, Cell Staining, RNA-Binding Proteins, Endoplasmic Reticulum Stress, Specimen preparation and treatment, 3. Good health, Chromatin, Cell biology, Nucleic acids, DNA-Binding Proteins, [SDV] Life Sciences [q-bio], Cell Processes, 030220 oncology & carcinogenesis, Helicobacter hepaticus, Research Article, QH301-705.5, Imaging Techniques, Substance-Related Disorders, DNA damage, Autophagic Cell Death, Bacterial Toxins, Immunology, ATG5, Intoxication, Nucleoplasmic reticulum, Microbiology, 03 medical and health sciences, Downregulation and upregulation, Virology, Fluorescence Imaging, Mental Health and Psychiatry, Autophagy, Genetics, Humans, Molecular Biology, 030304 developmental biology, Cell Nucleus, DAPI staining, Biology and Life Sciences, Cell Biology, DNA, RC581-607, biology.organism_classification, Research and analysis methods, Nuclear staining, Cancer cell, Hepatocytes, Parasitology, Immunologic diseases. Allergy, Mutagens

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f62fc30ec0486166039d9d5a067026d3Test
https://hal.sorbonne-universite.fr/hal-03160976Test

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