المؤلفون: Nauder Faraday, Brian D. Hobbs, Quan Sun, Michael Preuss, Ani Manichaikul, Eric Jorgenson, Ming-Huei Chen, Eric Boerwinkle, Florian Thibord, Arunoday Bhan, Alanna C. Morrison, Ramachandran S. Vasan, Nathan Pankratz, Charles Kooperberg, Deborah A. Nickerson, Joshua P. Lewis, Hélène Choquet, Jee-Young Moon, Jeffrey R. O'Connell, Marsha M. Wheeler, Albert V. Smith, Russell P. Tracy, Nathalie Chami, Ruth J. F. Loos, Alexander P. Reiner, Nicholas L. Smith, Gonçalo R. Abecasis, Laura M. Raffield, Amarise Little, Nancy L. Heard-Costa, Andrew D. Johnson, David C. Glahn, Rasika A. Mathias, Adam S. Butterworth, John Blangero, Joanne E. Curran, Timothy A. Thornton, Laura Almasy, Jerome I. Rotter, Nancy Min, Lisa R. Yanek, Donald M. Lloyd-Jones, Zhe Wang, Matthew P. Conomos, Myriam Fornage, Hua Tang, Lewis C. Becker, Lynette Ekunwe, Cecelia A. Laurie, Adolfo Correa, Jai G. Broome, Terri H. Beaty, Jennifer A. Brody, Caitlin P. McHugh, Yao Hu, Braxton D. Mitchell, Lifang Hou, Yun Li, Kathleen A. Ryan, Paul L. Auer, Stephen S. Rich, Kari E. North, Thomas W. Blackwell, Bruce M. Psaty, Deepti Jain, Paul S Vries, Praveen Surendran

المساهمون: Butterworth, Adam [0000-0002-6915-9015], Apollo - University of Cambridge Repository

المصدر: Human molecular genetics, vol 31, iss 3
Hum Mol Genet

مصطلحات موضوعية: Blood Platelets, Platelet disorder, Population, Genome-wide association study, Biology, Quantitative trait locus, Polymorphism, Single Nucleotide, Medical and Health Sciences, Genome, 03 medical and health sciences, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, 0302 clinical medicine, Clinical Research, and Blood Institute (U.S.), Genetics, Humans, 2.1 Biological and endogenous factors, Polymorphism, Precision Medicine, Aetiology, Mean platelet volume, education, Hemostatic function, Lung, Molecular Biology, Genetics (clinical), 030304 developmental biology, Blood Platelet Disorders, Genetics & Heredity, 0303 health sciences, education.field_of_study, Human Genome, Single Nucleotide, National Heart, Hematology, General Medicine, Biological Sciences, United States, 3. Good health, Phenotype, Good Health and Well Being, 030220 oncology & carcinogenesis, General Article, National Heart, Lung, and Blood Institute (U.S.), Genome-Wide Association Study, Biotechnology

وصف الملف: application/pdf; application/octet-stream

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fc9557e325812482460ef4586ad1a77Test
https://doi.org/10.1093/hmg/ddab252Test

المؤلفون: Laura M. Raffield, Michael Preuss, Danyu Lin, Charles Kooperberg, Alexander P. Reiner, Antoine R Baldassari, Colleen M. Sitlani, Christy L. Avery, Laura M. Huckins, Ruth J. F. Loos, Katherine K. Nishimura, Lihong Qi, Yao Hu, Abdou Mousas, Mariaelisa Graff, Bharat Thyagarajan, Yun Li, Ran Tao, Guillaume Lettre, Quan Sun, Heather M. Highland, Jeffrey Haessler, Myriam Fornage, Kari E. North, Ulrike Peters, Chani J. Hodonsky, Weihong Tang, Zhe Wang, Paul L. Auer, Steve Buyske, Ming-Huei Chen, Stephanie A. Bien, Lucia A. Hindorff, Genevieve L. Wojcik

المصدر: BMC Genomics, Vol 22, Iss 1, Pp 1-11 (2021)
BMC Genomics

مصطلحات موضوعية: Platelets, medicine.medical_specialty, Population, Ethnic group, Genome-wide association study, Genomics, Multi-ethnic, Biology, QH426-470, Polymorphism, Single Nucleotide, 03 medical and health sciences, White blood cell, Epidemiology, medicine, Leukocytes, Genetics, Humans, GWAS, Genetic Predisposition to Disease, education, Gene, 030304 developmental biology, Genetic association, 0303 health sciences, education.field_of_study, 030305 genetics & heredity, Correction, medicine.anatomical_structure, Phenotype, White blood cells, TP248.13-248.65, Research Article, Genome-Wide Association Study, Biotechnology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08259d0a7ba341a3d0b6a4a39fbba78dTest
https://doaj.org/article/492ab9ab7f354c8e890b3502d9d97085Test

المؤلفون: Andrew D Beswick, Tõnu Esko, Niki Dimou, Xue Zhong, Jette Bork-Jensen, Petra Schubert, Masato Akiyama, Girish N. Nadkarni, Ruth J. F. Loos, Huijun Qian, Michele K. Evans, Stephen S. Rich, Nicole Soranzo, Henry Völzke, Yongmei Liu, Nicholas A. Watkins, Markus M. Lerch, Richard C. Trembath, Adam S. Butterworth, Erwin P. Bottinger, Jennifer E. Huffman, Bruce M. Psaty, Jingzhong Ding, Michael Preuss, Yoav Ben-Shlomo, Bhavi Trivedi, Yoichiro Kamatani, David A. van Heel, Kjell Nikus, Torben Hansen, Adolfo Correa, Mohsen Ghanbari, Paul L. Auer, Véronique Laplante, Ken Sin Lo, Hua Tang, Peter W.F. Wilson, Paul Elliott, David J. Roberts, Hilary C. Martin, Jean-Claude Tardif, Praveen Surendran, Regina Manansala, Terho Lehtimäki, Emanuele Di Angelantonio, Fotis Koskeridis, Alexander P. Reiner, Mélissa Beaudoin, Vijay G. Sankaran, Benjamin Rodriguez, William J. Astle, Parsa Akbari, Frank J. A. van Rooij, Yun Li, Andreas Greinacher, Abdou Mousas, Andrew D. Johnson, Yukinori Okada, Michael H. Guo, Leo-Pekka Lyytikäinen, Traci M. Bartz, Minhui Chen, Alan B. Zonderman, Niels Grarup, Oluf Pedersen, Kumaraswamynaidu Chitrala, Jeffrey Haessler, Ming-Huei Chen, Cassandra N. Spracklen, Karen L. Mohlke, Guillaume Lettre, Erik L. Bao, Bingshan Li, James S. Floyd, Wei Huang, Ani Manichaikul, John Danesh, Uwe Völker, Allan Linneberg, Evangelos Evangelou, Joanna M. M. Howson, Olli T. Raitakari, Tim Kacprowski, Jean-François Gauchat, Hélène Choquet, Arden Moscati, Saori Sakaue, Mika Kähönen, Linda Broer, Caleb A. Lareau, Qin Qin Huang, Matthias Nauck, Yoshinori Murakami, Charleston W. K. Chiang, VA Million Veteran Program, Nina Mononen, Tao Jiang, Laura M. Raffield, Jerome I. Rotter, Leslie A. Lange, Jonathan D. Rosen, Eric Jorgenson, Savita Karthikeyan, Karen A. Hunt, Nathan Pankratz, Kelly Cho, Masahiro Kanai, Willem H. Ouwehand, Jennifer A. Brody, Koichi Matsuda, Dragana Vuckovic

المساهمون: Epidemiology, Internal Medicine

المصدر: Cell
Lettre, G & Auer, P L 2020, ' Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations ', Cell, vol. 182, no. 5, pp. 1198-1213.e14 . https://doi.org/10.1016/j.cell.2020.06.045Test
Cell, 182(5), 1198-1213.e14. Cell Press
Chen, M-H, Raffield, L M, Mousas, A, Sakaue, S, Huffman, J E, Moscati, A, Trivedi, B, Jiang, T, Akbari, P, Vuckovic, D, Bao, E L, Zhong, X, Manansala, R, Laplante, V, Chen, M, Lo, K S, Qian, H, Lareau, C A, Beaudoin, M, Hunt, K A, Akiyama, M, Bartz, T M, Ben-Shlomo, Y, Beswick, A, Bork-Jensen, J, Bottinger, E P, Brody, J A, van Rooij, F J A, Chitrala, K, Cho, K, Choquet, H, Correa, A, Danesh, J, Di Angelantonio, E, Dimou, N, Ding, J, Elliott, P, Esko, T, Evans, M K, Floyd, J S, Broer, L, Grarup, N, Guo, M H, Greinacher, A, Haessler, J, Hansen, T, Howson, J M M, Linneberg, A, Pedersen, O, Loos, R J F & VA Million Veteran Program 2020, ' Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations ', Cell, vol. 182, no. 5, pp. 1198-+ . https://doi.org/10.1016/j.cell.2020.06.045Test

مصطلحات موضوعية: LOCI, Mutation, Missense, Ethnic group, POLYGENIC RISK SCORES, HUMAN HEMATOPOIESIS, Biology, BIOBANK, phenome-wide association study, Polymorphism, Single Nucleotide, DISEASE, White People, General Biochemistry, Genetics and Molecular Biology, Article, Blood cell, 03 medical and health sciences, SINGLE-CELL, selective sweeps, 0302 clinical medicine, Asian People, parasitic diseases, Genetics, medicine, Humans, GENOME-WIDE ASSOCIATION, 030304 developmental biology, AFRICAN-AMERICANS, 0303 health sciences, interleukin-7, Interleukin-7, genetic architecture, Genetic architecture, TRAIT, HEK293 Cells, Phenotype, medicine.anatomical_structure, fine-mapping, polygenic trait score, lipids (amino acids, peptides, and proteins), FREQUENCY CODING VARIANTS, 030217 neurology & neurosurgery, Genome-Wide Association Study

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1811f60972354d4d9bffd608966f4eaTest
https://pure.eur.nl/en/publications/b0512e42-bb15-4b65-9524-08ef2dd4cd7dTest

المؤلفون: Ming-Huei Chen, Laura M. Raffield, Abdou Mousas, Saori Sakaue, Jennifer E. Huffman, Tao Jiang, Parsa Akbari, Dragana Vuckovic, Erik L. Bao, Arden Moscati, Xue Zhong, Regina Manansala, Véronique Laplante, Minhui Chen, Ken Sin Lo, Huijun Qian, Caleb A. Lareau, Mélissa Beaudoin, Masato Akiyama, Traci M. Bartz, Yoav Ben-Shlomo, Andrew Beswick, Jette Bork-Jensen, Erwin P. Bottinger, Jennifer A. Brody, Frank J.A. van Rooij, Kumaraswamynaidu Chitrala, Kelly Cho, Hélène Choquet, Adolfo Correa, John Danesh, Emanuele Di Angelantonio, Niki Dimou, Jingzhong Ding, Paul Elliott, Tõnu Esko, Michele K. Evans, James S. Floyd, Linda Broer, Niels Grarup, Michael H. Guo, Andreas Greinacher, Jeff Haessler, Torben Hansen, Joanna M. M. Howson, Wei Huang, Eric Jorgenson, Tim Kacprowski, Mika Kähönen, Yoichiro Kamatani, Masahiro Kanai, Savita Karthikeyan, Fotis Koskeridis, Leslie A. Lange, Terho Lehtimäki, Markus M. Lerch, Allan Linneberg, Yongmei Liu, Leo-Pekka Lyytikäinen, Ani Manichaikul, Koichi Matsuda, Karen L. Mohlke, Nina Mononen, Yoshinori Murakami, Girish N. Nadkarni, Matthias Nauck, Kjell Nikus, Willem H. Ouwehand, Nathan Pankratz, Oluf Pedersen, Michael Preuss, Bruce M. Psaty, Olli T. Raitakari, David J. Roberts, Stephen S. Rich, Benjamin A.T. Rodriguez, Jonathan D. Rosen, Jerome I. Rotter, Petra Schubert, Cassandra N. Spracklen, Praveen Surendran, Hua Tang, Jean-Claude Tardif, Mohsen Ghanbari, Uwe Völker, Henry Völzke, Nicholas A. Watkins, Alan B. Zonderman, VA Million Veteran Program, Peter W.F. Wilson, Yun Li, Adam S. Butterworth, Jean-François Gauchat, Charleston W.K. Chiang, Bingshan Li, Ruth J.F. Loos, William J. Astle, Evangelos Evangelou, Vijay G. Sankaran, Yukinori Okada, Nicole Soranzo, Andrew D. Johnson, Alexander P. Reiner, Paul L. Auer, Guillaume Lettre

مصطلحات موضوعية: Blood cell, Genetics, 0303 health sciences, 03 medical and health sciences, 0302 clinical medicine, medicine.anatomical_structure, 030220 oncology & carcinogenesis, medicine, Ethnic group, Genome-wide association study, Biology, 030304 developmental biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f628af808f38d9ca9ae061174848ae3Test
https://doi.org/10.1101/2020.01.17.910497Test

المؤلفون: Nicholas A. Watkins, Julian C. Knight, William J. Astle, Stephan B. Felix, Petra Schubert, Andreas Greinacher, Laura M. Raffield, Guillaume Lettre, Leslie A. Lange, Erwin P. Bottinger, Jonathan D. Rosen, Frank J. A. van Rooij, Tim Kacprowski, Hua Tang, Regina Manansala, Manuel Tardaguila, Mohsen Ghanbari, Tao Jiang, Torben Hansen, Abdou Mousas, Adam S. Butterworth, Yoav Ben-Shlomo, Praveen Surendran, Terho Lehtimäki, Peter W.F. Wilson, Parsa Akbari, Hélène Choquet, Niels Grarup, Girish N. Nadkarni, Jean-Claude Tardif, Jennifer E. Huffman, Dragana Vuckovic, Ruth J. F. Loos, Karyn Megy, Emilie M. Wigdor, Michael Preuss, Alan B. Zonderman, Yukinori Okada, Oluf Pedersen, Arden Moscati, Leo-Pekka Lyytikäinen, Masahiro Kanai, Wei Huang, Andrew D Beswick, Stephen B. Watt, Erik L. Bao, Allan Linneberg, Paul Elliott, Eric Jorgenson, Tõnu Esko, Michael H. Guo, VA Million Veteran Program, Saori Sakaue, Mika Kähönen, Olli T. Raitakari, Stefan Weiss, Traci M. Bartz, Nina Mononen, Jette Bork-Jensen, Willem H. Ouwehand, Linda Broer, John Danesh, Masato Akiyama, James S. Floyd, Scott C. Ritchie, Kjell Nikus, Paul L. Auer, Emanuele Di Angelantonio, Ken Sin Lo, Kelly Cho, Uwe Völker, Ming-Huei Chen, Evangelos Evangelou, David J. Roberts, Na Cai, Benjamin Rodriguez, Savita Karthikeyan, Yoichiro Kamatani, Michael Inouye, Yoshinori Murakami, Yongmei Liu, Alexander P. Reiner, Koichi Matsuda, Jingzhong Ding, Kumaraswamy Naidu Chitrala, Niki Dimou, Andrew D. Johnson, Nathan Pankratz, Jeffrey Haessler, Vijay G. Sankaran, Oliver Stegle, Qi Guo, Karen L. Mohlke, Jennifer A. Brody, Michele K. Evans, Fotios Koskeridis, Cassandra N. Spracklen, Jerome I. Rotter, Ani Manichaikul, Patrick K. Albers, Caleb A. Lareau, Michel Georges, Hannes Ponstingl, Stephen S. Rich, Nicole Soranzo, Bruce M. Psaty, Yun Li, Klaudia Walter, Huijun Qian, Henry Völzke, Christopher J. Penkett, J. M. M. Howson, Kousik Kundu

المساهمون: Epidemiology, Internal Medicine

المصدر: 1231.e11
Cell, 182(5), 1214-1231.e11. Cell Press
Cell
Vuckovic, D, Ben-Shlomo, Y, Sankaran, V G & Soranzo, N 2020, ' The Polygenic and Monogenic Basis of Blood Traits and Diseases ', Cell, vol. 182, no. 5, pp. 1214-1231 E11 . https://doi.org/10.1016/j.cell.2020.08.008Test
Vuckovic, D, Bao, E L, Akbari, P, Lareau, C A, Mousas, A, Jiang, T, Chen, M-H, Raffield, L M, Tardaguila, M, Huffman, J E, Ritchie, S C, Megy, K, Ponstingl, H, Penkett, C J, Albers, P K, Wigdor, E M, Sakaue, S, Moscati, A, Manansala, R, Lo, K S, Qian, H, Akiyama, M, Bartz, T M, Ben-Shlomo, Y, Beswick, A, Bork-Jensen, J, Bottinger, E P, Brody, J A, van Rooij, F J A, Chitrala, K N, Wilson, P W F, Choquet, H, Danesh, J, Di Angelantonio, E, Dimou, N, Ding, J, Elliott, P, Esko, T, Evans, M K, Felix, S B, Floyd, J S, Broer, L, Grarup, N, Guo, M H, Guo, Q, Greinacher, A, Hansen, T, Linneberg, A, Pedersen, O, Loos, R J F & VA Million Veteran Program 2020, ' The Polygenic and Monogenic Basis of Blood Traits and Diseases ', Cell, vol. 182, no. 5, pp. 1214-1231 . https://doi.org/10.1016/j.cell.2020.08.008Test

مصطلحات موضوعية: Gene regulatory network, LOCI, EFFICIENT, Genome-wide association study, VARIANTS, Blood cell, 0302 clinical medicine, RARE, genetics, 11 Medical and Health Sciences, 0303 health sciences, rare diseases, Biobank, ddc, medicine.anatomical_structure, fine-mapping, VA Million Veteran Program, symbols, Life Sciences & Biomedicine, Biochemistry & Molecular Biology, UK Biobank, polygenic risk, rare disease, Computational biology, Biology, Article, General Biochemistry, Genetics and Molecular Biology, GENETIC ARCHITECTURE, 03 medical and health sciences, symbols.namesake, splicing, blood, medicine, CELL, Allele, GENOME-WIDE ASSOCIATION, COMMON, 030304 developmental biology, Science & Technology, COMPLEX, Oxygen transport, Cell Biology, 06 Biological Sciences, Genetic architecture, hematopoiesis, INTERROGATION, Mendelian inheritance, chromatin, omnigenic, 030217 neurology & neurosurgery, Developmental Biology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::141ceeacddd8287d8205b27678ae67a9Test

المؤلفون: Jeffrey R. O'Connell, L. Adrienne Cupples, Alan R. Shuldiner, Braxton D. Mitchell, Ali R. Keramati, Lisa R. Yanek, Lewis C. Becker, Brady Gaynor, Kanika Kanchan, Achilleas N. Pitsillides, Joshua P. Lewis, Ming-Huei Chen, Kai Kammers, Nauder Faraday, Rasika A. Mathias, Kruthika R. Iyer, Madeline H. Kowalski, Benjamin Rodriguez, Jennifer A. Brody, Margaret A. Taub, Andrew D. Johnson, Nhlbi TOPMed Hematology, Kathleen A. Ryan

مصطلحات موضوعية: Whole genome sequencing, 0303 health sciences, Regulator, Locus (genetics), Computational biology, 030204 cardiovascular system & hematology, Biology, DNA sequencing, 3. Good health, 03 medical and health sciences, 0302 clinical medicine, Super-enhancer, Expression quantitative trait loci, Epigenetics, Gene, 030304 developmental biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdbdd69b3c5101017553fd77f51d3b3fTest

المؤلفون: James L. Januzzi, Kai C. Wollert, Lars Lind, Erik Ingelsson, Thomas J. Wang, Cecilia M. Lindgren, Elizabeth L. McCabe, Jennifer E. Ho, Andrew P. Morris, Susan Cheng, Tibor Kempf, Anahita Ghorbani, Anubha Mahajan, Ming-Huei Chen, Martin G. Larson, Andrew D. Johnson, Ramachandran S. Vasan

المصدر: Clinical Chemistry. 58:1582-1591

مصطلحات موضوعية: Male, medicine.medical_specialty, Growth Differentiation Factor 15, Offspring, Quantitative Trait Loci, Clinical Biochemistry, Locus (genetics), Genome-wide association study, 030204 cardiovascular system & hematology, Quantitative trait locus, Biology, Polymorphism, Single Nucleotide, Article, Cohort Studies, 03 medical and health sciences, 0302 clinical medicine, Risk Factors, Internal medicine, Diabetes mellitus, medicine, Humans, Genetic Predisposition to Disease, Aged, 030304 developmental biology, 0303 health sciences, Framingham Risk Score, Cholesterol, HDL, Biochemistry (medical), Middle Aged, medicine.disease, 3. Good health, Endocrinology, Cardiovascular Diseases, Multivariate Analysis, Female, GDF15, Genome-Wide Association Study, Cohort study

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daec179300e15edf27ffd800174ac971Test
https://doi.org/10.1373/clinchem.2012.190322Test

المؤلفون: Jens Baumert, Gerjan Navis, Shelly G. Smith, Peter J. Grant, Anders Hamsten, Frances M K Williams, Russell P. Tracy, James B. Meigs, Maria Grazia Franzosi, Angela M. Carter, François Cambien, Wiek H. van Gilst, Kent D. Taylor, Folkert W. Asselbergs, Marcus E. Kleber, Kurt Lohman, Scott M. Williams, Saonli Basu, Martina Müller-Nurasyid, Angela Silveira, Pim van der Harst, Rory Collins, Geoffrey H. Tofler, Lasse Folkersen, Wolfgang Koenig, Christa Meisinger, Christopher J. O'Donnell, Qiong Yang, Aaron R. Folsom, John C. Chambers, Muredach P. Reilly, Norman Klopp, Weihong Tang, Ming-Huei Chen, Mahir Karakas, Bernhard R. Winkelmann, John Danesh, Sekar Kathiresan, Tamara B. Harris, Tim D. Spector, Pierre-Emmanuel Morange, John F. Peden, Danish Saleheen, Jaspal S. Kooner, Ann-Christine Syvänen, David-Alexandre Trégouët, Winfried März, Bernhard O. Boehm, Robert Clarke, Tiphaine Oudot-Mellakh, Nicholas L. Smith, Vinh Truong, Mary Cushman, André G. Uitterlinden, Lewis C. Becker, Joshua C. Bis, Udo Seedorf, Bengt Sennblad, Anders Franco-Cereceda, Yongmei Liu, Elisabeth M. C. Schrijvers, Hugh Watkins, Barbara McKnight, Diane M. Becker, Jingzhong Ding, Nicole Soranzo, Bruce M. Psaty, Anuj Goel, Per Eriksson, Mohammad Arfan Ikram, Annette Peters, So-Youn Shin, Abbas Dehghan, Lisa R. Yanek, Albert Hofman, Jason H. Moore, Hans L. Hillege, Per Lundmark, Jie Huang, Günther Silbernagel, Jemma C. Hopewell, John Öhrvik, Nena Matijevic, Alison H. Goodall, Maria Sabater-Lleal, Josyf C. Mychaleckyj, Rona J. Strawbridge, Andrew D. Johnson

المساهمون: Radiology & Nuclear Medicine, Epidemiology, Neurology, Internal Medicine, Life Course Epidemiology (LCE), Cardiovascular Centre (CVC), Lifestyle Medicine (LM), Groningen Kidney Center (GKC), Vascular Ageing Programme (VAP)

المصدر: Blood
Blood, 120(24), 4873-4881. American Society of Hematology
Blood, 120(24), 4873-4881. AMER SOC HEMATOLOGY
Blood; Vol 120

مصطلحات موضوعية: Candidate gene, Genome-wide association study, Coronary Artery Disease, 030204 cardiovascular system & hematology, CIRCADIAN CLOCK, PLASMINOGEN-ACTIVATOR INHIBITOR-1, Biochemistry, TYPE-1 EXPRESSION, Monocytes, Thrombosis and Hemostasis, Cohort Studies, 0302 clinical medicine, Gene Frequency, Genetics, RISK, 0303 health sciences, ARNTL Transcription Factors, GENETIC-VARIATION, Hematology, LIM Domain Proteins, 3. Good health, ARNTL, CORONARY-ARTERY-DISEASE, RNA Interference, Proteasome Endopeptidase Complex, SUSCEPTIBILITY LOCI, Genotype, Immunology, Single-nucleotide polymorphism, Biology, Polymorphism, Single Nucleotide, Cell Line, 03 medical and health sciences, SDG 3 - Good Health and Well-being, Meta-Analysis as Topic, Cell Line, Tumor, Plasminogen Activator Inhibitor 1, SNP, Humans, PLASMA-LEVELS, Allele frequency, 030304 developmental biology, Adaptor Proteins, Signal Transducing, Mucin-3, Gene Expression Profiling, Cell Biology, Molecular biology, Gene expression profiling, PPAR gamma, MYOCARDIAL-INFARCTION, Diabetes Mellitus, Type 2, Gene Expression Regulation, TISSUE, ATPases Associated with Diverse Cellular Activities, Genome-Wide Association Study, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5b86409435b3e3ad600f075d3e1bb70Test

المؤلفون: W. H. Linda Kao, Nicole Probst-Hensch, Florian Ernst, Paul Mitchell, Christa Meisinger, Florian Kronenberg, Sharon L.R. Kardia, Paul M. Ridker, Vilmundur Gudnason, Jeanette S. Andrews, Ming-Huei Chen, Frank B. Hu, Jean-Charles Lambert, Mario Pirastu, Ozren Polasek, Xiaoyi Gao, Sven Bergmann, Catherine Helmer, Wilmar Igl, Jie Jin Wang, Barry I. Freedman, Anke Tönjes, Jacqueline C. M. Witteman, Sheila Ulivi, Conall M. O'Seaghdha, Mika Kähönen, Mariza de Andrade, Daniel I. Chasman, Meredith C. Foster, Rossella Sorice, Mathias Gorski, Eric Boerwinkle, Karlhans Endlich, Maksim Struchalin, Bernhard K. Krämer, Bénédicte Stengel, Caroline Hayward, Giorgio Pistis, Andres Metspalu, Peter Kovacs, Jorma Viikari, Guo Li, Cristian Pattaro, Adrienne Tin, Igor Rudan, Christian Gieger, Mary F. Feitosa, Stephen T. Turner, Gary C. Curhan, Shamika Ketkar, Ian Ford, Peter Vollenweider, Wolfgang Koenig, Madhumathi Rao, Iris M. Heid, Stuart K. Kim, Heather E. Wheeler, Matthias Olden, Hinco J. Gierman, Alex S. F. Doney, Lenore J. Launer, Mladen Boban, Georg Homuth, Paolo Gasparini, Harshal Deshmukh, Henry Völzke, Daniela Ruggiero, Medea Imboden, Elizabeth J. Atkinson, Ben A. Oostra, Stefan Coassin, Ute Nöthlings, Marilyn C. Cornelis, David S. Siscovick, Yongmei Liu, Gian Andri Thun, Gunnar Jacobs, Franco Giulianini, Uwe Völker, Tõnu Esko, Alexander Teumer, Jeffrey R. O'Connell, Brendan M. Buckley, Heyo K. Kroemer, Albert V. Smith, Ulf Gyllensten, Federico Murgia, Man Li, Harry Campbell, Antonietta Robino, Abbas Dehghan, Inga Prokopenko, Shih-Jen Hwang, Sylvia Stracke, Michael Stumvoll, Alan R. Shuldiner, Christian Fuchsberger, Claudia Hundertmark, Luigi Ferrucci, David Ellinghaus, Laura Portas, Caroline S. Fox, Afshin Parsa, Carsten A. Böger, Toshiko Tanaka, Terho Lehtimäki, Ayse Demirkan, James F. Wilson, Elizabeth G. Holliday, Yurii S. Aulchenko, Murielle Bochud, Helen M. Colhoun, Jingzhong Ding, Nicole L. Glazer, Rainer Rettig, Bernhard Paulweber, Margherita Cavalieri, Andre Franke, Ingrid B. Borecki, Olli T. Raitakari, Josef Coresh, Tamara B. Harris, Sarah H. Wild, Reinhold Schmidt, Ching-Ti Liu, Zoltán Kutalik, André G. Uitterlinden, J. Wouter Jukema, Helena Schmidt, Martin Adam, Audrey Y. Chu, Fernando Rivadeneira, Cornelia M. van Duijn, Braxton D. Mitchell, Gudny Eiriksdottir, Tatijana Zemunik, Andrew D. Johnson, Ghazal Zaboli, Reiner Biffar, Thor Aspelund, Cinzia Sala, Peter P. Pramstaller, Veronique Vitart, Michael A. Province, Anna Köttgen, Nicholas D. Hastie, Daniel Taliun, Marina Ciullo, Cosetta Minelli, Kurt Lohman, Matthias Nauck, Thomas Illig, Alan F. Wright, Albert Hofman, Colin N. A. Palmer, Daniela Toniolo, Qiong Yang, Lina Zgaga, Åsa Johansson, Margot Haun, Stella Trompet, Aaron Isaacs, Reedik Mägi, Tiit Nikopensius

المساهمون: Epidemiology, Erasmus School of Social and Behavioural Sciences, Clinical Genetics, Internal Medicine, Chasman, Di, Fuchsberger, C, Pattaro, C, Teumer, A, Böger, Ca, Endlich, K, Olden, M, Chen, Mh, Tin, A, Taliun, D, Li, M, Gao, X, Gorski, M, Yang, Q, Hundertmark, C, Foster, Mc, O'Seaghdha, Cm, Glazer, N, Isaacs, A, Liu, Ct, Smith, Av, O'Connell, Jr, Struchalin, M, Tanaka, T, Li, G, Johnson, Ad, Gierman, Hj, Feitosa, Mf, Hwang, Sj, Atkinson, Ej, Lohman, K, Cornelis, Mc, Johansson, A, Tönjes, A, Dehghan, A, Lambert, Jc, Holliday, Eg, Sorice, R, Kutalik, Z, Lehtimäki, T, Esko, T, Deshmukh, H, Ulivi, S, Chu, Ay, Murgia, F, Trompet, S, Imboden, M, Coassin, S, Pistis, G, Cardiogram, Consortium, Icbp, Consortium, the CARe, Consortium, Wtccc2, Harris, Tb, Launer, Lj, Aspelund, T, Eiriksdottir, G, Mitchell, Bd, Boerwinkle, E, Schmidt, H, Cavalieri, M, Rao, M, Hu, F, Demirkan, A, Oostra, Ba, de Andrade, M, Turner, St, Ding, J, Andrews, J, Freedman, Bi, Giulianini, F, Koenig, W, Illig, T, Meisinger, C, Gieger, C, Zgaga, L, Zemunik, T, Boban, M, Minelli, C, Wheeler, He, Igl, W, Zaboli, G, Wild, Sh, Wright, Af, Campbell, H, Ellinghaus, D, Nöthlings, U, Jacobs, G, Biffar, R, Ernst, F, Homuth, G, Kroemer, Hk, Nauck, M, Stracke, S, Völker, U, Völzke, H, Kovacs, P, Stumvoll, M, Mägi, R, Hofman, A, Uitterlinden, Ag, Rivadeneira, F, Aulchenko, Y, Polasek, O, Hastie, N, Vitart, V, Helmer, C, Wang, Jj, Stengel, B, Ruggiero, D, Bergmann, S, Kähönen, M, Viikari, J, Nikopensius, T, Province, M, Ketkar, S, Colhoun, H, Doney, A, Robino, Antonietta, Krämer, Bk, Portas, L, Ford, I, Buckley, Bm, Adam, M, Thun, Ga, Paulweber, B, Haun, M, Sala, C, Mitchell, P, Ciullo, M, Kim, Sk, Vollenweider, P, Raitakari, O, Metspalu, A, Palmer, C, Gasparini, Paolo, Pirastu, M, Jukema, Jw, Probst Hensch, Nm, Kronenberg, F, Toniolo, D, Gudnason, V, Shuldiner, Ar, Coresh, J, Schmidt, R, Ferrucci, L, Siscovick, D, van Duijn, Cm, Borecki, Ib, Kardia, Sl, Liu, Y, Curhan, Gc, Rudan, I, Gyllensten, U, Wilson, Jf, Franke, A, Pramstaller, Pp, Rettig, R, Prokopenko, I, Witteman, J, Hayward, C, Ridker, Pm, Parsa, A, Bochud, M, Heid, Im, Kao, Wl, Fox, C, Köttgen, A.

المصدر: Human Molecular Genetics, 21(24), 5329-5343. Oxford University Press
Human Molecular Genetics
Human Molecular Genetics; Vol 21
Human Molecular Genetics, 21(24), 5329-5343
Human Molecular Genetics, 21(24), 5329-43. Oxford University Press

مصطلحات موضوعية: Candidate gene, Amino Acid Transport Systems, Basic/genetics, Genome-wide association study, Gene, Genome, Inhibin-beta Subunits/genetics, GWAS, kidney, eGFR, Genetics (clinical), Inhibin-beta Subunits, Glomerular Filtration Rate/genetics, Genetics, 0303 health sciences, Genetic Predisposition to Disease/genetics, Association Studies Articles, 030305 genetics & heredity, Intracellular Signaling Peptides and Proteins, General Medicine, Low Density Lipoprotein Receptor-Related Protein-2/genetics, Polymorphism, Single Nucleotide/genetics, LRP2, 3. Good health, Low Density Lipoprotein Receptor-Related Protein-2, Genome-Wide Association Study/methods, Single Nucleotide/genetics, Glomerular Filtration Rate, Fusion Regulatory Protein 1, Heavy Chain, Single-nucleotide polymorphism, Biology, Polymorphism, Single Nucleotide, 03 medical and health sciences, Genome-Wide Association Studies, Humans, SNP, Genetic Predisposition to Disease, ddc:610, Membrane Proteins/genetics, Polymorphism, Molecular Biology, 030304 developmental biology, Genetic association, Fusion Regulatory Protein 1, Heavy Chain/genetics, Fusion Regulatory Protein 1, Genes, Kidney Function, Membrane Proteins, ta3121, Amino Acid Transport Systems, Basic, Amino Acid Transport Systems, Basic/genetics, Heavy Chain/genetics, Intracellular Signaling Peptides and Proteins/genetics, Candidate Disease Gene, Genome-Wide Association Study

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c85f6d1aa3bf9ab2abbe237f5fa0e34fTest
http://juuli.fi/Record/0252336712Test

المؤلفون: Geoffrey H. Tofler, Peter M. Visscher, Gail Davies, Brendan M. Buckley, Albert Tenesa, Ann Rumley, John M. Starr, Xiuqing Guo, Veronique Vitart, Nicole Soranzo, Ozren Polasek, Rudi G. J. Westendorp, Jennifer E. Huffman, André G. Uitterlinden, Barbara Thorand, Igor Rudan, Naveed Sattar, Bruce M. Psaty, Ming-Huei Chen, Jens Baumert, Mary Cushman, Qiong Yang, Ian J. Deary, Stella Trompet, Lorna M. Lopez, Mahir Karakas, Drazen Pulanic, Alicja R Rudnicka, Peter J. Grant, So-Youn Shin, Edwin G. Bovill, Thomas Illig, Sarah H. Wild, Abbas Dehghan, Gordon D.O. Lowe, Jacqueline C. M. Witteman, Anton J. M. de Craen, Christian Gieger, Nicholas D. Hastie, Ian Ford, J. Wouter Jukema, Nicholas L. Smith, Wendy L. McArdle, Thomas Lumley, David J. Stott, James F. Wilson, Harry Campbell, Jie Huang, Albert Hofman, Susan Campbell, Annette Peters, Wolfgang Koenig, Barbara McKnight, Michelle Luciano, Angela M. Carter, Christopher J. O'Donnell, Tim D. Spector, David P. Strachan, Alan F. Wright, P. Eline Slagboom, David J. Porteous, Sarah E. Harris, Alan J. Gow, Caroline Hayward, Joshua C. Bis, David C. Liewald

المساهمون: Epidemiology, Internal Medicine

المصدر: Circulation
Smith, N L, Huffman, J E, Strachan, D P, Huang, J, Dehghan, A, Trompet, S, Lopez, L M, Shin, S-Y, Baumert, J, Vitart, V, Bis, J C, Wild, S H, Rumley, A, Yang, Q, Uitterlinden, A G, Stott, D J, Davies, G, Carter, A M, Thorand, B, Polašek, O, McKnight, B, Campbell, H, Rudnicka, A R, Chen, M-H, Buckley, B M, Harris, S E, Peters, A, Pulanic, D, Lumley, T, de Craen, A J M, Liewald, D C, Gieger, C, Campbell, S, Ford, I, Gow, A J, Luciano, M, Porteous, D J, Guo, X, Sattar, N, Tenesa, A, Cushman, M, Slagboom, P E, Visscher, P M, Spector, T D, Illig, T, Rudan, I, Bovill, E G, Wright, A F, McArdle, W L, Tofler, G, Hofman, A, Westendorp, R G J, Starr, J M, Grant, P J, Karakas, M, Hastie, N D, Psaty, B M, Wilson, J F, Lowe, G D O, O'Donnell, C J, Witteman, J C M, Jukema, J W, Deary, I J, Soranzo, N, Koenig, W & Hayward, C 2011, ' Genetic Predictors of Fibrin D-Dimer Levels in Healthy Adults ', Circulation, vol. 123, no. 17, pp. 1864-1872 . https://doi.org/10.1161/circulationaha.110.009480Test
Circulation; Vol 123
Circulation, 123(17), 1864
Circulation, 123(17), 1864-+. Lippincott Williams & Wilkins

مصطلحات موضوعية: Male, Plasmin, Genome-wide association study, 030204 cardiovascular system & hematology, Fibrinogen, polymorphism, 0302 clinical medicine, Reference Values, thr312ala, risk, Genetics, 0303 health sciences, biology, von-willebrand-factor, Factor V, cardiovascular health, Middle Aged, myocardial-infarction, epidemiology fibrin fragment D genome-wide association study hemostasis meta-analysis thrombosis genome-wide association tissue-plasminogen activator coronary heart-disease von-willebrand-factor venous thromboembolism thr312ala polymorphism cardiovascular health myocardial-infarction aging research risk, Female, epidemiology, Cardiology and Cardiovascular Medicine, medicine.drug, Adult, venous thromboembolism, Locus (genetics), Fibrin, White People, Article, Thromboplastin, Fibrin Fibrinogen Degradation Products, 03 medical and health sciences, Physiology (medical), Genetic model, D-dimer, medicine, Humans, Genetic Testing, Blood Coagulation, coronary, thrombosis, 030304 developmental biology, Aged, genome-wide association study, research, fibrin fragment D, business.industry, aging, heart-disease, tissue-plasminogen activator, meta-analysis, Immunology, biology.protein, hemostasis, genome-wide association, business, Genome-Wide Association Study

وصف الملف: application/pdf; text

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac337c57847acf041254fa2f5d29f5f2Test