نتائج البحث - "Type I interferon production"

1

SOCS-1 inhibition of type I interferon restrains Staphylococcus aureus skin host defense

المؤلفون: Sydney Castellanos, Nathan Klopfenstein, C. Henrique Serezani, Matthias Gunzer, Stephanie L. Brandt, Amondrea Blackman

المصدر: PLoS Pathogens, Vol 17, Iss 3, p e1009387 (2021)
PLoS Pathogens

مصطلحات موضوعية: Neutrophils, Staphylococcus, Biopsy, Medizin, Skin infection, medicine.disease_cause, Biochemistry, White Blood Cells, Mice, 0302 clinical medicine, Medical Conditions, Interferon, Animal Cells, Medicine and Health Sciences, Biology (General), Pathology and laboratory medicine, Skin, 0303 health sciences, Phagocytes, Effector, Medical microbiology, Infectious Diseases, Staphylococcus aureus, Interferon Type I, Staphylococcal Skin Infections, medicine.symptom, Pathogens, Cellular Types, medicine.drug, Research Article, Skin Infections, Methicillin-Resistant Staphylococcus aureus, QH301-705.5, Immune Cells, Immunology, Inflammation, Surgical and Invasive Medical Procedures, Dermatology, Biology, Skin Diseases, Microbiology, 03 medical and health sciences, Suppressor of Cytokine Signaling 1 Protein, Virology, Genetics, medicine, otorhinolaryngologic diseases, Animals, Molecular Biology, 030304 developmental biology, Innate immune system, Blood Cells, Biology and life sciences, Bacteria, Suppressor of cytokine signaling 1, Macrophages, Organisms, Proteins, Cell Biology, RC581-607, medicine.disease, Type I interferon production, Microbial pathogens, Mice, Inbred C57BL, Parasitology, Bacterial pathogens, Interferons, Immunologic diseases. Allergy, 030215 immunology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b6ca3bf6e5ea34f9af1269656212964Test
https://doaj.org/article/1779f18dc5e84c0fbac6cebf2508449dTest

2

PPP6C Negatively Regulates STING-Dependent Innate Immune Responses

المؤلفون: Guoxin Ni, Blossom Damania, M. Ben Major, Zhe Ma, Jason P. Wong, Zhigang Zhang, Emily M. Cousins

المصدر: mBio, Vol 11, Iss 4 (2020)
mBio

مصطلحات موضوعية: Herpesvirus 1, Human, KSHV, Biology, Virus Replication, Microbiology, Host-Microbe Biology, PPP6C, phosphatase, 03 medical and health sciences, 0302 clinical medicine, Virology, Chlorocebus aethiops, Phosphoprotein Phosphatases, Animals, Humans, Protein phosphorylation, Vero Cells, 030304 developmental biology, PP6C, 0303 health sciences, Innate immune system, phosphorylation, Membrane Proteins, Signal transducing adaptor protein, Vesiculovirus, interferon, herpes simplex virus, Type I interferon production, HSV-1, Immunity, Innate, QR1-502, eye diseases, Kaposi's sarcoma-associated herpesvirus, protein phosphorylation, Cell biology, interferons, Sting, HEK293 Cells, Gene Expression Regulation, VSV, Stimulator of interferon genes, Host-Pathogen Interactions, Phosphorylation, Interferon Regulatory Factor-3, vesicular stomatitis virus, IRF3, 030217 neurology & neurosurgery, Research Article, STING

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b304d3b5f75e6b4cf19c1d368f783a9Test
https://doi.org/10.1128/mbio.01728-20Test

3

Inhibition of mTORC1 Enhances the Translation of Chikungunya Proteins via the Activation of the MnK/eIF4E Pathway

المؤلفون: Matthew L. Albert, Florence Guivel-Benhassine, Pierre-Emmanuel Joubert, Olivier Schwartz, Kenneth A. Stapleford, Marco Vignuzzi

المساهمون: Immunobiologie des Cellules dendritiques, Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), Populations virales et Pathogenèse - Viral Populations and Pathogenesis, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Virus et Immunité - Virus and immunity, Virus et Immunité, Centre National de la Recherche Scientifique (CNRS)-Institut Pasteur [Paris], Centre d'Immunologie Humaine (CIH), This work was supported by La Ligue Contre le Cancer and L’Agence Nationale de la Recherche. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript., Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Virus et Immunité - Virus and immunity (CNRS-UMR3569), Ziani, Isma

المصدر: PLoS Pathogens
PLoS Pathogens, Public Library of Science, 2015, 11 (8), pp.e1005091. ⟨10.1371/journal.ppat.1005091⟩
PLoS Pathogens, 2015, 11 (8), pp.e1005091. ⟨10.1371/journal.ppat.1005091⟩
PLoS Pathogens, Vol 11, Iss 8, p e1005091 (2015)

مصطلحات موضوعية: [SDV]Life Sciences [q-bio], Gene Knockout Techniques, Mice, Phosphatidylinositol 3-Kinases, 0302 clinical medicine, Protein biosynthesis, RNA, Small Interfering, lcsh:QH301-705.5, 0303 health sciences, TOR Serine-Threonine Kinases, EIF4E, virus diseases, Translation (biology), Flow Cytometry, 3. Good health, Cell biology, [SDV] Life Sciences [q-bio], 030220 oncology & carcinogenesis, Chikungunya virus, Research Article, Signal Transduction, lcsh:Immunologic diseases. Allergy, Blotting, Western, Immunology, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, Mechanistic Target of Rapamycin Complex 1, Biology, Transfection, Microbiology, Host-Parasite Interactions, Viral Proteins, 03 medical and health sciences, Viral life cycle, Virology, Genetics, Animals, Gene silencing, Molecular Biology, [SDV.BC] Life Sciences [q-bio]/Cellular Biology, PI3K/AKT/mTOR pathway, 030304 developmental biology, Blotting, Northern, Type I interferon production, Disease Models, Animal, Eukaryotic Initiation Factor-4E, lcsh:Biology (General), Viral replication, Multiprotein Complexes, Protein Biosynthesis, Chikungunya Fever, Parasitology, lcsh:RC581-607

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8016201c395f38fb56955d18020b675Test
https://hal-pasteur.archives-ouvertes.fr/pasteur-01372397/documentTest

4

Modulation of innate immune signalling by lipid-mediated MAVS transmembrane domain oligomerization

المؤلفون: Luis Nobre, Daniel Wise, David Ron, Romain Volmer

المساهمون: Cambridge Institute for Medical Research (CIMR), University of Cambridge [UK] (CAM), Wellcome Trust, National Institute for Health Research (NHS), Interactions hôtes-agents pathogènes [Toulouse] (IHAP), Institut National de la Recherche Agronomique (INRA)-Ecole Nationale Vétérinaire de Toulouse (ENVT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université de Toulouse (UT), Wellcome Trust Intermediate Clinical Fellowship [093764], Wellcome Trust Principal Research Fellowship [084812], Wellcome Trust [100140], European Project: 277713,EC:FP7:HEALTH,FP7-HEALTH-2011-two-stage,BETABAT(2011), Ron, David [0000-0002-3014-5636], Apollo - University of Cambridge Repository, Nobre, Luis, Wise, Daniel, Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées

المصدر: PLoS ONE
PLoS ONE, 2015, 10 (8), ⟨10.1371/journal.pone.0136883⟩
PLoS ONE, Vol 10, Iss 8, p e0136883 (2015)
Plos One 8 (10), . (2015)
PLoS ONE, Public Library of Science, 2015, 10 (8), ⟨10.1371/journal.pone.0136883⟩

مصطلحات موضوعية: Recombinant Fusion Proteins, [SDV]Life Sciences [q-bio], lcsh:Medicine, Mitochondrion, Biology, Respirovirus Infections, Sendai virus, 03 medical and health sciences, 0302 clinical medicine, Humans, Protein Interaction Domains and Motifs, Lipid bilayer, Inner mitochondrial membrane, lcsh:Science, 030304 developmental biology, Adaptor Proteins, Signal Transducing, 0303 health sciences, Multidisciplinary, Innate immune system, lcsh:R, Signal transducing adaptor protein, Lipid signaling, Type I interferon production, Immunity, Innate, 3. Good health, Cell biology, Mitochondria, Transmembrane domain, HEK293 Cells, lcsh:Q, Lipid Peroxidation, Reactive Oxygen Species, 030217 neurology & neurosurgery, Research Article

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72ed61dd84549b669a013d5b305b15e7Test
https://hal.inrae.fr/hal-02632377Test

5

Intact Type I Interferon Production and IRF7 Function in Sooty Mangabeys

المؤلفون: Guido Silvestri, Tayebeh Hashempour, Perla M. Del Rio Estrada, Kathryn A. Folkner, Nirav B. Patel, Steven E. Bosinger, Simon P. Jochems, John Hiscott, Zachary P. Johnson, Rongtuan Lin, Mirko Paiardini, Thomas H. Vanderford

المصدر: PLoS Pathogens
PLoS Pathogens, Vol 9, Iss 8, p e1003597 (2013)

مصطلحات موضوعية: Male, Interferon Regulatory Factor-7, DNA Mutational Analysis, Simian Acquired Immunodeficiency Syndrome, HIV Infections, medicine.disease_cause, 0302 clinical medicine, Interferon, Biology (General), 0303 health sciences, Imidazoles, Exons, Innate Immunity, 3. Good health, Quinolines, Cytokines, Medicine, Infectious diseases, Female, Simian Immunodeficiency Virus, medicine.drug, Research Article, Signal Transduction, QH301-705.5, Immunology, Retrovirology and HIV immunopathogenesis, Active Transport, Cell Nucleus, Mutation, Missense, Alpha interferon, Viremia, Immunopathology, Viral diseases, Biology, Microbiology, Peripheral blood mononuclear cell, 03 medical and health sciences, Cercocebus atys, Immune system, Virology, Genetics, medicine, Animals, Humans, RNA, Messenger, Molecular Biology, 030304 developmental biology, Inflammation, Cell Nucleus, Immunity, HIV, Interferon-alpha, Dendritic Cells, Interferon-beta, RC581-607, Simian immunodeficiency virus, Type I interferon production, medicine.disease, Amino Acid Substitution, Toll-Like Receptor 7, Immune System, HIV-1, Leukocytes, Mononuclear, IRF7, Parasitology, Immunologic diseases. Allergy, 030215 immunology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::734a5361528cb1b4a4ad81a237bc026eTest
http://europepmc.org/articles/PMC3757038Test

6

CD20 antibody primes B lymphocytes for type I interferon production

المؤلفون: Dongsheng Xu, Luwen Zhang, Andrew Staedman

المصدر: PLoS ONE
PLoS ONE, Vol 8, Iss 6, p e67900 (2013)

مصطلحات موضوعية: Time Factors, Dose-Response Relationship, Immunologic, lcsh:Medicine, 03 medical and health sciences, Antibodies, Monoclonal, Murine-Derived, 0302 clinical medicine, Antigen, immune system diseases, hemic and lymphatic diseases, medicine, Humans, lcsh:Science, skin and connective tissue diseases, B cell, 030304 developmental biology, 030203 arthritis & rheumatology, CD20, 0303 health sciences, B-Lymphocytes, Multidisciplinary, Systemic lupus erythematosus, biology, lcsh:R, Type I interferon production, medicine.disease, Antigens, CD20, Immunity, Innate, 3. Good health, medicine.anatomical_structure, HEK293 Cells, Immunology, Interferon Type I, biology.protein, Rituximab, lcsh:Q, Antibody, Interferon type I, medicine.drug, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3054c7b4286c3dc1ecde20cba52164d2Test
https://pubmed.ncbi.nlm.nih.gov/23874371Test

7

MAVS ubiquitination by the E3 ligase TRIM25 and degradation by the proteasome is involved in type I Interferon production after activation of the antiviral RIG-I-Like receptors

المؤلفون: Alain Portier, Nicolas Bidère, Aimé Vazquez, Dominique Garcin, Naima Zemirli, Damien Arnoult, Céline Castanier

المساهمون: Régulation de la survie cellulaire et des allogreffes, Université Paris-Sud - Paris 11 (UP11)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM), Department of Microbiology and Molecular Medicine, University of Geneva [Switzerland]-School of Medicine, This work was supported by grants from Agence Nationale de La Recherche sur le SIDA (ANRS), La Ligue contre le cancer (équipe labellisée), Association pour la Recherche sur le Cancer (ARC) and the Université Paris Sud XI., BMC, Ed., Université de Genève = University of Geneva (UNIGE)-School of Medicine

المصدر: BMC Biology
BMC Biology, BioMed Central, 2012, 10 (1), pp.44. ⟨10.1186/1741-7007-10-44⟩
BMC Biology, Vol 10, Iss 1, p 44 (2012)
BMC Biology, Vol. 10 (2012) P. 44
BMC biology

مصطلحات موضوعية: Scaffold protein, Interferon Type I/immunology, Physiology, viruses, [SDV]Life Sciences [q-bio], Plant Science, Sendai virus, DEAD-box RNA Helicases, Tripartite Motif Proteins, 0302 clinical medicine, Ubiquitin, Structural Biology, Phosphorylation, lcsh:QH301-705.5, DEAD-box RNA Helicases/immunology/metabolism, ddc:616, 0303 health sciences, biology, Agricultural and Biological Sciences(all), RIG-I, NF-kappa B, I-kappa B Kinase/metabolism, Protein-Serine-Threonine Kinases/metabolism, MAVS, Ubiquitin ligase, Cell biology, I-kappa B Kinase, [SDV] Life Sciences [q-bio], 030220 oncology & carcinogenesis, Interferon Type I, Signal transduction, General Agricultural and Biological Sciences, Biotechnology, Research Article, Signal Transduction, TRIM25, Proteasome Endopeptidase Complex, Interferon Regulatory Factor-3/metabolism, Ubiquitin-Protein Ligases, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, Protein Serine-Threonine Kinases, ubiquitination, Respirovirus Infections, General Biochemistry, Genetics and Molecular Biology, Respirovirus Infections/immunology/metabolism, 03 medical and health sciences, Ubiquitin-Protein Ligases/metabolism, Humans, Transcription Factors/metabolism, [SDV.BC] Life Sciences [q-bio]/Cellular Biology, Ecology, Evolution, Behavior and Systematics, 030304 developmental biology, Adaptor Proteins, Signal Transducing, Sendai virus/immunology/metabolism, Biochemistry, Genetics and Molecular Biology(all), Ubiquitination, Cell Biology, Type I interferon production, Molecular biology, Proteasome Endopeptidase Complex/metabolism, Adaptor Proteins, Signal Transducing/metabolism, HEK293 Cells, lcsh:Biology (General), NF-kappa B/metabolism, biology.protein, RIG-I-like receptors, Interferon Regulatory Factor-3, IRF3, Developmental Biology, Transcription Factors, HeLa Cells