In vitro, in vivo, and clinical tests of a novel flexible ureteroscope for the diagnosis and treatment of kidney and ureteral diseases
| العنوان: | In vitro, in vivo, and clinical tests of a novel flexible ureteroscope for the diagnosis and treatment of kidney and ureteral diseases |
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| المؤلفون: | Choung-Soo Kim, Hyung Keun Park, Dai Hee Kim, Jung Hyun Shin, Dalsan You, Se Young Choi |
| المصدر: | Investigative and Clinical Urology Investigative and Clinical Urology, Vol 59, Iss 5, Pp 328-334 (2018) |
| بيانات النشر: | The Korean Urological Association, 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Clinical tests, Urology, medicine.medical_treatment, 030232 urology & nephrology, Lithotripsy, lcsh:RC870-923, Nephrolithiasis, 03 medical and health sciences, 0302 clinical medicine, medicine, In vitro in vivo, Flexible ureteroscope, Kidney, URETEROSCOPE, business.industry, Ureteral Diseases, lcsh:Diseases of the genitourinary system. Urology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Ureteroscopes, Endourology/Urolithiasis, Original Article, Nuclear medicine, business |
| الوصف: | Purpose Despite advances in flexible ureteroscopy, the high cost and long repair time of ureteroscopes limit their use in the urology. We compared the performance of a novel flexible ureteroscope (fURS) 'HF-EH' with that of the two contemporary fURSs 'URF-P6' and 'COBRA'. Materials and methods We compared in vitro measurements of deflection angle, irrigation flow rate, and image quality between HF-EH and URF-P6 while also inspecting renal collecting systems in five female pigs. For clinical testing, we performed retrograde intrarenal surgeries using HF-EH in four patients. Experienced urologists compared performance parameters (irrigation, convenience, and maneuverability) between the HF-EH and COBRA. Results The flow rate of HF-EH (21.0 mL/min) was worse, and its resolution (1.59 line pairs/mm) was inferior to that of URF-P6 (28.7 mL/min and 3.17 line pairs/mm, respectively). However, HF-EH was superior to URF-P6 in terms of loss of deflection angle with the insertion of accessories (1.8% vs. 12.7%). In vivo and clinical testing revealed that the performance parameters of HF-EH were slightly inferior to those of conventional domestic fURSs. We successfully performed retrograde intrarenal surgeries using HF-EH in four patients and achieved stone-free statuses in two. None of the patients exhibited any procedure-related complications. Conclusions Although we observed that two of the three performance parameters of the novel ureteroscope 'HF-EH' were inferior to those of the conventional ureteroscope, we successfully used HF-EH to perform retrograde intrarenal surgeries in patients. Further studies on performance and durability are warranted for making HF-EH commercially available. |
| اللغة: | English |
| تدمد: | 2466-054X 2466-0493 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9038e2fa4a11ebf14c8b92d1b8c54888Test http://europepmc.org/articles/PMC6121019Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....9038e2fa4a11ebf14c8b92d1b8c54888 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 2466054X 24660493 |
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